KyungLab

Ultra Hydrating Cream

• A natural moisturizer that’s also in our skin
• A super common, safe, effective and cheap molecule used for more than 50 years
• Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
• Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
• High-glycerin moisturizers are awesome for treating severely dry skin

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

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• A multi-functional skincare superstar with several proven benefits for the skin
• Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
• Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
• Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
• Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis

We don't have description for this ingredient yet.

A silicone emulsifier that helps water and silicone oils to mix nicely together. It can also be used together with plant oil + silicone oil mixtures. 

A white, elastomeric silicone powder that gives a nice silky and powdery feel to the products. It also has some oil and sebum absorption capabilities. 

A silicone emulsifier that helps water and silicone oils to mix nicely together. 

A sugar beet-derived amino acid derivative with nice skin protection and moisturization properties. Betaine's special thing is being an osmolyte, a molecule that helps to control cell-water balance.  It is also a natural osmoprotectant, meaning that it attracts water away from the protein surface and thus protects them from denaturation and increases their thermodynamic stability. 

It also gives sensorial benefits to the formula and when used in cleansers, it helps to make them milder and gentler. 

Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!). 

If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.  

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Centella Asiatica - or sometimes also called Gotu Kola or Cica - has been used in folk medicine for hundreds of years. It’s traditionally used to improve small wounds, burns and scratches and it’s also a well known anti-inflammatory agent for eczema.

Recently science has taken an interest in Gotu Kola as well and it turns out it really has many active compounds with several benefits. Just for hard-core geeks, the main biologically active compounds are pentacyclic triterpenoid saponins called asiaticoside, madecassoside, asiatic and madecassic acid (also called centellosides).

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We don't have description for this ingredient yet.

A traditional Chinese herbal medicine loaded with potent antioxidant and anti-inflammatory flavonoids such as baicalin, baicalein, and wogonin.

If that would not be enough, Skullcap Root is also claimed to have antimicrobial and antifungal properties (also against P.acnes and Malassezia furfur) as well as some skin-brightening activity. A multi-functional skin-goodie.

• Green tea is one of the most researched natural ingredients
• The active parts are called polyphenols, or more precisely catechins (EGCG being the most abundant and most active catechin)
• There can be huge quality differences between green tea extracts. The good ones contain 50-90% catechins (and often make the product brown and give it a distinctive smell)
• Green tea is proven to be a great antioxidant, UV protectant, anti-inflammatory, anticarcinogenic and antimicrobial
• Because of these awesome properties green tea is a great choice for anti-aging and also for skin diseases including rosacea, acne and atopic dermatitis

You might know licorice as a sweet treat from your childhood, but it's actually a legume that grows around the Mediterranean Sea, the Middle East, central and southern Russia. It's sweet and yellow and not only used for licorice all sorts but it's also a skincare superstar thanks to two magic properties:

Nr. 1 magic property is that it has skin-lightening or to say it another way depigmenting properties. The most active part is called glabridin. The topical application (meaning when you put it on your face) of 0.5% glabridin was shown to inhibit UVB caused pigmentation of guinea pigs. Another study even suggested that licorice is more effective than the gold standard skin-lightening agent hydroquinone. All in all, licorice is considered to be one of the safest skin lightening agents with the fewest side effects.

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Chamomile probably needs no introduction as it's one of the most widely used medicinal herbs. You probably drink it regularly as a nice, calming cup of tea and it's also a regular on skincare ingredient lists.

Cosmetic companies use it mainly for its anti-inflammatory properties. It contains the terpenoids chamazulene and bisabolol both of which show great anti-inflammatory action in animal studies. On top of that chamomile also has some antioxidant activity (thanks to some other active ingredients called matricine, apigenin and luteolin).  

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The extract coming from the lovely herb, rosemary. It contains lots of chemicals, including flavonoids, phenolic acids, and diterpenes. Its main active is rosmarinic acid, a potent antioxidant, and anti-inflammatory. It has also anti-bacterial, astringent and toning properties. 

The leaves contain a small amount of essential oil (1-2%) with fragrant components, so if you are allergic to fragrance, it might be better to avoid it. 

Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved. 

It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. 

A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent and a broad spectrum antimicrobial. According to manufacturer info, it's also a moisturizer and helps to make the product feel great on the skin. It works synergistically with preservatives and helps to improve water-resistance of sunscreens. 

The extract coming from the coconut fruit. It is a similar thing to coconut water and fruit juice and is loaded with sugars, minerals, amino acids. It is also claimed to have vitalizing and energizing effects, and some smoothing, emollient and hydrating props.

If you are into coconut, we have more details at coconut water and coconut oil. 

We don't have description for this ingredient yet.

A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives. 

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

The extract created from the leaves of the hazelnut-bush-like-magic-tree, commonly called Witch Hazel. We have gone into detail about Witch Hazel in cosmetic products here (it's astringent, soothing, antioxidant and antibacterial), but the important part to know about the leaves is that they contain much, much less active components than the bark. In fact, it contains hardly any tannins (only 0.04%) and the most active component in the leaves is the antibacterial gallic acid. 

Too many tannins can be very astringent and irritating to the skin, so this is not necessarily a bad thing. Even the small amount of active components in the leaves seem to give it nice soothing, astringent, and antibacterial properties. 

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The extract coming from the popular garden plant Calendula or Marigold. According to manufacturer info, it's used  for many centuries for its exceptional healing powers and is particularly remarkable in the treatment of wounds. It contains flavonoids that give the plant anti-inflammatory and antioxidant properties. 

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Sodium Acetylated Hyaluronate is a variation of current IT moisturizer, Hyaluronic acid, where some water-loving -OH groups are replaced by amphipathic (partly water-loving and partly water-hating) acetyl groups. The modified molecule is claimed to have even better moisture retention ability than normal HA and better affinity to the skin surface. 

The better affinity comes from the acetyl groups that act as tiny "anchors" to attach the HA molecule to the skin. Staying on top of the skin better and longer means longer-lasting surface hydration and improved elasticity. It is also less sticky and more cosmetically elegant than normal HA, so no wonder the nickname of this molecule is super hyaluronic acid. 

Hydrolyzed Hyaluronic Acid is a low molecular weight, chemically chopped up version of the naturally big molecule and current IT-moisturizer, Hyaluronic Acid (HA). The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to retain water, making it plump and elastic. As HA is a polymer, the subunits can be repeated many times (as a high-molecular-weight version), or just a few times (as a low-molecular-weight version).

We wrote in detail at HA about how different molecular weight versions do different things both as a component of the skin and as a skincare ingredient, so click here and read about all the details. Hydrolyzed Hyaluronic Acid can also come in different molecular-weight versions with different properties:

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We don't have description for this ingredient yet.

Sh-Oligopeptide-1 is the famous molecule, which is also called Epidermal Growth Factor or EGF. Chemically speaking, Growth Factors are largish peptides or smallish proteins, or to put it in another way, medium-length amino acid sequences (EGF consists of 53 amino acids).  Biologically speaking, Growth Factors are cellular signal molecules that can stimulate cell growth, proliferation, healing and/or differentiation. 

There are lots of Growth Factors and EGF is just one of them. The topic of "Growth Factors and skincare" is a big, confusing and controversial one and we will try our best to summarize the story for you, including the pros and the cons. 

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Sh-Polypeptide-1 is a cell signaling protein also called Basic Fibroblast Growth Factor and is twin sister to Acidic Fibroblast Growth Factor. We can write here pretty much the same things as we did on aFGF: it is a mitogenic (= stimulates cell proliferation) ingredient that stimulates fibroblast cell growth and proliferation. According to manufacturer info, it also stimulates the synthesis of collagen and other extracellular-matrix (the gooey stuff between cells) components. 

Growth Factors and skincare is a big, complicated and controversial topic, so if you wanna know more, we have a more detailed explanation on Epidermal Growth Factor, the most common one used in skincare.

We don't have description for this ingredient yet.

If you see a cosmetic product that claims that it has "Botox-like effect" then two things are almost certain: one, the product overpromises and two, it contains Argireline. 

So this one is the famous peptide that's marketed by its manufacturer as the "Botox in a jar". The basis for this claim is that it targets the same wrinkle forming mechanism (wrinkles caused by facial muscle movement) as Botox, but the way it works is very different. In addition, the extent to which it can prevent muscles from contracting (and to smooth wrinkles) is very different (otherwise why would anyone use still Botox?). 

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Acetyl Hexapeptide-1 is a bit of a special snowflake among peptides as it's not a wrinkle-smoothing, anti-aging active like most of the other ones but it can stimulate pigmentation and melanin production (by interacting with a skin cell receptor called MC1R).

As melanin not only gives the skin its nice tanned color but also works as a natural protection factor, Acetyl Hexapeptide-1, aka Melitane does the same.  It not only boosts a natural or an artificial tan but gives extra protection against UV-induced DNA and free radical damage and protects the skin against UV-caused redness. 

We don't have description for this ingredient yet.

A four amino acid peptide that is claimed to mimic the youth hormone called thymopoietin. It works by compensating the loss of thymic factors that come with age and is thought to stimulate the skin immune defenses and to help the skin regenerate. 

A relatively new, four amino acid peptide that promises to help combat hair loss alongside red clover extract as part of the trademarked technology Capixyl. 

The main thing of  Acetyl Tetrapeptide-3 is to stimulate the synthesis of key Extra Cellular Matrix (aka ECM, the gooey stuff between cells that make up the framework of our skin) components in the scalp.  According to the manufacturer’s lab studies, the expression of type III collagen increased by 65% and the expression of laminins (anchoring proteins found in the ECM) was up a massive 285%, resulting in a stronger ECM bed for hair anchoring.

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A four amino acid peptide that is claimed to mimic the youth hormone called thymopoietin. It works by compensating the loss of thymic factors that come with age and is thought to stimulate the skin immune defenses and to help the skin regenerate. 

We don't have description for this ingredient yet.

Though its name does not reveal it, Carnosine is a peptide, a small, two amino acid (β-Ala-His) one. It is naturally present in high concentrations in muscle and brain tissues, but the one used in cosmetic products is biomimetic, meaning that it is synthetically produced in a lab to copy the natural thing. 

A 2017 review paper on topical peptides writes about Carnosine that it is a "well-documented aqueous antioxidant with wound healing activity".  

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• GHK-Cu is a copper-peptide complex found naturally in yucky bodily fluids (plasma, saliva, and urine)
• It has unique wound healing properties by stimulating the breakdown of unhealthy, too large collagen in scar tissue and stimulating nice and healthy collagen production afterwards
• It stimulates the production of several important skin-identical ingredients (e.g. collagen, elastin, and glycosaminoglycans)
• It has significant anti-inflammatory and antioxidant effect
• There are a few promising studies showing GHK-Cu can improve skin elasticity, clarity, firmness and reduce lines and wrinkles
• It can improve hair growth by enlarging hair follicles (and bigger follicles produce longer, thicker hair)
• There are some urban legends about possible overdosing or facial hair problems (read more in geeky details)

A tiny peptide with only two amino acids (amino acids are the building block of proteins, and peptides are a few amino acids attached together), Valine and Tryptophan. It's part of a 3 actives complex called Eyeliss (with HMC and Palmitoyl Tetrapeptide-7) that's supposed to fight under-eye bags. 

The manufacturer claims that this dipeptide in Eyeliss can increase lymphatic circulation and the three actives together represent a "global approach to treating puffy eyes". The clinical study of the manufacturer with 20 people and 3% Eyeliss showed improvement after 56 days for 70% of the participants.

An anti-aging peptide that can visibly reduce the length and depth of wrinkles, at least according to its manufacturer. In vitro (meaning it was done in the lab, not on real people) studies show that it enhances epidermal regeneration, collagen type I and III synthesis as well as the synthesis of other important skin proteins. 

We don't have description for this ingredient yet.

A pretty famous and better-researched peptide consisting of five amino acids (the building blocks of all proteins). It was created in a joint effort by the French ingredient supplier, Sederma and the cosmetics industry big shot, Procter&Gamble.

The amino acid sequence of the peptide is lysine–threonine–threonine–lysine–serine (KTTKS). Sometimes, it's also called collagen pentapeptide, as it's a subfragment of skin-structure-giving type I collagen. The KTTKS amino sequence is then attached for better oil solubility and skin penetration to palmitic acid and BOOM; we get Palmitoyl Pentapeptide-4. 

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A four amino acid peptide with the amino sequence of glycine-glutamine-proline-arginine. It is attached to palmitic acid (a fatty acid)  to increase oil solubility and skin penetration. 

It works by reducing the production of the signal molecule, interleukin-6 (IL-6) which promotes inflammation in the skin and less inflammation means slower degradation of important things (like collagen) that results in younger looking skin for a longer time. 

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A really famous peptide that is part of Matrixyl 3000, the most sold peptide complex in the word. Before we go and find out what the big deal with Matrixyl 3000 is, let's just focus on Palmitoyl Tripeptide-1 itself for a bit.

It's a small three amino acid (they are the building blocks of all proteins) peptide with the amino sequence of glycine-histidine-lysine, or GHK. GHK is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration. 

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A tripeptide (three amino acids attached to each other: Lys-Val-Lys) that's claimed to protect and boost collagen and improve skin texture.

The manufacturer did an in-vivo (made on real people) study with 45 volunteers and found that used twice daily for 84 days 1% and 2.5% Syn-Coll reduces the appearance of wrinkles by 7 and 12% respectively. In another study (also by the manufacturer) with 33 female Chinese volunteers, 77% of the participants felt that Syn-Coll visibly improved the firmness and elasticity of the skin after 4 weeks. What's more, 60% of the participants also noticed a reduction in the look of the pore size also after 4 weeks of treatment. 

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

A small, three amino acid (glycine-histidine-lysine or GHK) peptide that is famous for being a type I collagen fragment. The theory behind collagen-fragment peptides is that when collagen naturally breaks down in the skin, the resulting peptide fragments signal to the skin that it should get to work and create some nice, new collagen.

Adding in collagen fragment peptides, like GHK, might trick the skin into thinking that collagen has broken down and it's time to create some more. So Tripeptide-1 is believed to be able to stimulate collagen production in the skin, and more collagen means fewer wrinkles and younger looking skin. FYI; Tripeptide-1 is the same peptide that can be found in the famous Matrixyl 3000, but in Matrixyl a palmitic acid is attached to it to increase its oil solubility and thus skin penetration.

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A three amino acid peptide where the famous collagen fragment, Tripeptide-1, aka GHK is combined with Biotin, the well-known supplement for stronger nails and hairs. The result of the combination is Biotinoyl Tripeptide-1, a peptide claimed to be helpful for reducing hair loss and for making the eyelashes appear longer, fuller, and stronger.

As for proof, the manufacturer did some in-vitro (made in test tubes) studies that show that our molecule can promote hair bulb keratinocyte proliferation and also helps optimal hair anchorage by stimulating the synthesis and organization of the adhesion molecules laminin 5 and collagen IV. This means that our peptide might help the hair to be stronger and to stay longer in its place, though these are only in vitro results that might or might not translate to real-world use. 

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A four amino acid peptide (Proline – Lysine – Glutamic Acid – Lysine; PKEK) whose main magic power is to fade hyperpigmentation (aka age spots) and even out the skin tone. 

According to its German manufacturer, Tetrapeptide-30 has a nice anti-inflammatory function that leads to a dual action in hindering the pigmentation process. It acts as a tyrosinase inhibitor (the famous enzyme needed to create melanin), and it also blocks the transfer of the melanin up into the top layers of the skin. 

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A newer and, molecule-wise, somewhat bigger version of the famous "Botox-like" peptide called Acetyl Hexapeptide-8 or Argireline. Just like Argireline, Acetyl Octapeptide-3 is also claimed to influence the muscle contraction process that results in a more relaxed and line-free face, especially around the forehead and the eyes.  

While Argireline counts as a pretty well-proven peptide, with multiple studies confirming its anti-wrinkle efficacy, we cannot say the same for Acetyl Octapeptide-3. What we have is the manufacturer's claim that comparing 10% Argireline with 10% SNAP-8 solution (that means 0.005% pure peptide powder) the SNAP-8 peptide did a bit better as it reduced wrinkles by 34.98% vs 27.05% reduction for Argireline (twice a day use for 28 days on 17 women). 

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We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

A four amino acid (Glycine – Glutamic acid – Lysine – Glycine) peptide that belongs to the group of signal peptides that mimic skin-protein breakdown products to trick the skin into creating some nice new skin proteins, such as collagen (if this sentence is not clear, here is a bit longer and nicer explanation). 

According to its manufacturer, Tetrapeptide-21 shows superior collagen, hyaluronic acid and fibronectin (all nice and important skin elements) boosting activity, and can smooth and minimize all kinds of wrinkles. The in-vitro data (made on human dermal fibroblast culture) showed that compared to Matrixyl (the first-generation Matrixyl peptide called Palmitoyl Pentapeptide-4), the collagen production in the presence of Tetrapeptide-21 was almost 2-fold higher (and about 2.5-fold vs the control). This data was confirmed by an in-vivo study that compared on 60 volunteers 0.5% Tego Pep 4-17 (10ppm of Tetrapeptide-21), 5% Tego Pep 4-17 (100ppm of Tetrapeptide-21) and 10% Matrixyl (10ppm of Palmitoyl Pentapeptide-4) and found that Tetrapeptide-21 performed better after 8 weeks for skin volume, roughness and elasticity. 

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A small, three-amino acid peptide (Glycine-Proline-Hydroxyproline) found naturally in our collagen structure.

The theory behind Tripeptide-29 is the following: Collagen is a long sequence of amino acids and breaking it down produces short amino acid sequences, aka peptides. These peptides "signal" to the skin that collagen was lost and that new collagen should be produced. So putting collagen-fragment-identical peptides on the skin might trick it into thinking that new collagen is needed. 

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We don't have description for this ingredient yet.

Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.

As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity. 

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Adenosine is an important little compound in our body that has a vital cell-signalling role. Research on smearing it on our face is also promising and shows so far a couple of things:

• It can help with wound healing
• It’s a good anti-inflammatory agent
• It might even help with skin’s own collagen production and improve skin firmness and elasticity
• It helps with barrier repair and protection
• It might be even useful for the hair helping with hair thickness and hair growth

Sodium chloride is the fancy name of salt. Normal, everyday table salt. 

If (similar to us) you are in the weird habit of reading the label on your shower gel while taking a shower, you might have noticed that sodium chloride is almost always on the ingredient list. The reason for this is that salt acts as a fantastic thickener in cleansing formulas created with ionic cleansing agents (aka surfactants) such as Sodium Laureth Sulfate. A couple of percents (typically 1-3%) turns a runny surfactant solution into a nice gel texture.

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