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Hesperidin Methyl Chalcone

Also-called-like-this: Part of Eyeliss
What-it-does: antioxidant


This guy - let's just call it simply HMC - is a so-called flavonoid (flavonoids are natural things found it lots of fruits and vegetables). Hesperidin, in particular, is a flavonone and is found in citrus fruits. The methylation of hesperidin gives HMC, that has well-established blood vessel protecting properties and can be found in drugs that treat problems related to blood vessels.

As for skincare, there is a mouse study showing HMC has very promising abilities in the "treatment of UVB irradiation-induced skin inflammation and oxidative stress", or English translation = it's an antioxidant and anti-inflammatory

HMC is also part of a 3 active ingredient complex called Eyeliss (with Dipeptide-2 and Palmitoyl Tetrapeptide-7), that's supposed to fight under-eye bags. The manufacturer claims that in their ex-vivo test HMC decreased capillary permeability by 25%.

All in all, HMC definitely deserves a goodie status, at least as an antioxidant but it might even do something with under-eye bags.

Show me some proof

  • Chemico-Biological Interactions, 25 February 2015, Protective effects of the flavonoid hesperidin methyl chalcone in inflammation and pain in mice: Role of TRPV1, oxidative stress, cytokines and NF-κB
  • Journal of Photochemistry and Photobiology B: Biology, Jul 1, 2015, Hesperidin methyl chalcone inhibits oxidative stress and inflammation in a mouse model of ultraviolet B irradiation-induced skin damage

Products with Hesperidin Methyl Chalcone

Isomers All-In-One Mesmer-Eyez Tightening Eye Formula AMBI Even And Clear Eye Serum Ari brands Under Eye Serum Dermadoctor Wrinkle Revenge Rescue And Protect Eye Balm Dermapeutics Super Anti-Oxidant Eye Lift Serum UniLipo Peptide Packed Eye Serum tSoS Eye Treatment AQ Skin Solutions Eye Serum Il Makiage Power Rewind NeoGenesis Eye Serum NeoGenesis Eye Serum Eyetitude Fixzer Instant Eye Repair Skin first Contorno Occhi Skoah. Eye Kandy Gel The Image Ageless Total Eye Lift Cream ACM Dépiwhite Eye Contour Gel ACM Laboratoire Dépiwhite Eye Contour Gel Ava Laboratorium Stop Time Rejuvenating Eye Contour Serum Dennis Knudsen Eye Gel ACM Duolys Eye Contour Cream Dermiq Capilite Tx Eva Mulia Eye Serum BB "Baggy Black" Serum FRNCH Eye Serum Natural Kirei Eye Lift Rare Paris Trésor Solaire Facial Mist Skin Authority Dramatic Eye Lift Tree of Life Beauty Vitamin C Eye Gel Eighth Day Eye Renewal Cream Joanna Vargas Bright Eye Hydrating Mask Medik8 Eyelift™ Peptides Ziaja Acai Berry Express Face And Neck Serum Acti labs Eye Contour Concentrate Di Morelli Eye Cream G.M. Collin Bota-Peptide Eye Contour Klorane Thickness & Vitality Leave-In Spray With Essential Olive Extract QMS Medicosmetics Epigen Depuff Pollution Shield Eye Serum REDNESS CARE FIRMING SERUM Renee Rouleau Redness Care Rare Paris Carbone Glacé - Masque Visage Purifiant Renee Rouleau Redness Care Firming Serum Simple Beauty Fine Line Eye Serum Verfons Snake Venom Peptide Brightens Eye Cream Avene Antirougeurs Calm Soothing Repair Mask Dr. Brandt Needles No More No More Baggage Klorane Smoothing And Soothing Eye Patches With Cornflower And Hyaluronic Acid Peter Thomas Roth Instant Firmx® Eye Temporary Eye Tightener Skin Actives Antioxidant Serum Skin Actives Scientific Antioxidant Serum Thin Lizzy Puffy Eye Remover V Magic Bee Venom Age Frozen Eye Cream Avene Antirougeurs Cleansing Milk Bottle