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Also-called-like-this: Insulin-like growth factor 1, IGF-1, rh-Oligopeptide-2


Sh-Oligopeptide-2 is also called Insulin-like growth factor 1 and it belongs to the same group of ingredients (Growth Factors) as its better-known sister, Epidermal Growth Factor or Sh-Oligopeptide-1. This guy consists of 70 amino acids and, similar to EGF, it is also claimed to stimulate cell proliferation and wound healing. There is also a study that indicates EGF and IGF1 work in synergy to promote keratinocyte (skin cell) proliferation. 

The topic of Growth Factors in skincare is complex and controversial. If you are new to it, read our shiny explanation on EGF to get a (hopefully) balanced impression about the pros and cons.

Show me some proof

  • Krane, Jeffrey F., et al. "Synergistic effects of epidermal growth factor (EGF) and insulin-like growth factor I/somatomedin C (IGF-I) on keratinocyte proliferation may be mediated by IGF-I transmodulation of the EGF receptor." Journal of investigative dermatology 96.4 (1991): 419-424.

Products with SH-Oligopeptide-2

Toskani Rcpr Eighth Day Regenerative Serum Manyo Factory 4Gf Eye Cream Sidmool Acetyl Ampoule Cellderma Gf5 Growth Factor Serum Eighth Day Regenerating Serum Skin Moderne Elementals Bio-placenta carrot & stick The Repair Serum hamel Double Shot 12gf Core Glow Mist Serum CLINERAL SKINPRO Medical Grade Skin Care PRP Growth Factor Facelift - Epidermal Growth Factor, HGF, LGF Facial Serum Ekseption Ice Cream Repair Larens Face Toner Yuri Pibu Bifida Repair Ampoule AnteAGE Overnight Brows Serum AnteAGE Overnight Lash Serum Be Minimalist Multi-Peptide Serum (7% Matrixyl 3000 + 3% Bio-Placenta) Catherine Jinn Age Gracefully Miamo GF5-GLUTATHIONE Rejuvenating Serum - Siero Anti-rughe – Antiossidante minimalist Multi-peptides 10% Acure Radically Rejuvenating Whipped Night Cream Acure Radically Rejuvenating Whipped Night Cream Swanicoco Peptine Biome Serum APLB Vitamin C Propolis Lotion Fusion Eye Sorbet Fusion Lift Sleeping Mask Le Mieux 24 Hour Age Defying Cream Yuri Pibu Cellum Amaid Ampoule Cellderma Youth Restore Drunk Elephant Protini™ Polypeptide Cream Drunk Elephant Protini™ Polypeptide Moisturizer Inked Ritual Anti-Fade Tattoo Serum Isntree Egf Repair Cream Isntree Egf Repair Cream Eighth Day Intensive Moisturizer Isagenix Celletoi™ Advanced Youth Serum Kate Somerville Kx Active Concentrates Bio-Mimicking Peptides Serum SID Systems Hair Growth Activator Sidmool Min Jung Gi Efi Eye Cream Sidmool Royal Honey Peptide Deep Moisture Sleeping Pack Swanicoco Fermentation Peptine Eye Care Cream Conscious Chemist The Defender™️ - Multi Peptide Retinol Night Cream May Island 7 Days Secret Peptide 8 Plus Toner Neulii Cicapepta Repair Serum Neulii Cicapepta Repair Serum Sidmool Dr. Galatok Galatokside Real Peptide Barrier Moisture Cream feelxo How Was It? Black Snail Serum APLB Bee Pollen Propolis Essence APLB Premium Lifting Ampoule Serum APLB Premium Rebooting Eye Cream Colibri Cosmetics Hyaluron Konzentrat