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Also-called-like-this: Insulin-like growth factor 1, IGF-1, rh-Oligopeptide-2


Sh-Oligopeptide-2 is also called Insulin-like growth factor 1 and it belongs to the same group of ingredients (Growth Factors) as its better-known sister, Epidermal Growth Factor or Sh-Oligopeptide-1. This guy consists of 70 amino acids and, similar to EGF, it is also claimed to stimulate cell proliferation and wound healing. There is also a study that indicates EGF and IGF1 work in synergy to promote keratinocyte (skin cell) proliferation. 

The topic of Growth Factors in skincare is complex and controversial. If you are new to it, read our shiny explanation on EGF to get a (hopefully) balanced impression about the pros and cons.

Show me some proof

  • Krane, Jeffrey F., et al. "Synergistic effects of epidermal growth factor (EGF) and insulin-like growth factor I/somatomedin C (IGF-I) on keratinocyte proliferation may be mediated by IGF-I transmodulation of the EGF receptor." Journal of investigative dermatology 96.4 (1991): 419-424.

Products with SH-Oligopeptide-2

Toskani Rcpr Eighth Day Regenerative Serum Manyo Factory 4Gf Eye Cream Sidmool Acetyl Ampoule Eighth Day Regenerating Serum Skin Moderne Elementals Bio-placenta CLINERAL SKINPRO Medical Grade Skin Care PRP Growth Factor Facelift - Epidermal Growth Factor, HGF, LGF Facial Serum Larens Face Toner Yuri Pibu Bifida Repair Ampoule AnteAGE Overnight Brows Serum AnteAGE Overnight Lash Serum Be Minimalist Multi-Peptide Serum (7% Matrixyl 3000 + 3% Bio-Placenta) Catherine Jinn Age Gracefully Miamo GF5-GLUTATHIONE Rejuvenating Serum - Siero Anti-rughe – Antiossidante Acure Radically Rejuvenating Whipped Night Cream Acure Radically Rejuvenating Whipped Night Cream Swanicoco Peptine Biome Serum Fusion Eye Sorbet Fusion Lift Sleeping Mask Le Mieux 24 Hour Age Defying Cream Yuri Pibu Cellum Amaid Ampoule Drunk Elephant Protini™ Polypeptide Cream Inked Ritual Anti-Fade Tattoo Serum Isntree Egf Repair Cream Isntree Egf Repair Cream Isagenix Celletoi™ Advanced Youth Serum Kate Somerville Kx Active Concentrates Bio-Mimicking Peptides Serum Sidmool Min Jung Gi Efi Eye Cream Sidmool Royal Honey Peptide Deep Moisture Sleeping Pack Swanicoco Fermentation Peptine Eye Care Cream Conscious Chemist The Defender™️ - Multi Peptide Retinol Night Cream Neulii Cicapepta Repair Serum Neulii Cicapepta Repair Serum Sidmool Dr. Galatok Galatokside Real Peptide Barrier Moisture Cream feelxo How Was It? Black Snail Serum Colibri Cosmetics Hyaluron Konzentrat Elizavecca Vitamin C 21% Ample Mask Murad Nutrient-Charged Water Gel Pixi DetoxifEYE Serum Sidmool Dr.galatok Galatokside Real N.m.f Barrier Serum Sidmool Madagascar Ultra Moisture Cream Swanicoco Peptine Biome Cream Swanicoco Peptine Biome Emulsion body blitz Plump It Up Serum Buona Vita Skin Factor Dermarium The Rescuer Manyo Factory 4GF Ampoule Eye Cream Nurse Jamie EGF Platinum 7 Rejuvenating Facial Cream Sculplla Promoter Repair Eye Cream TOV Beauty Hop+ Plla H2 Promoter Repair Eye Cream