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Also-called-like-this: Insulin-like growth factor 1, IGF-1, rh-Oligopeptide-2


Sh-Oligopeptide-2 is also called Insulin-like growth factor 1 and it belongs to the same group of ingredients (Growth Factors) as its better-known sister, Epidermal Growth Factor or Sh-Oligopeptide-1. This guy consists of 70 amino acids and, similar to EGF, it is also claimed to stimulate cell proliferation and wound healing. There is also a study that indicates EGF and IGF1 work in synergy to promote keratinocyte (skin cell) proliferation. 

The topic of Growth Factors in skincare is complex and controversial. If you are new to it, read our shiny explanation on EGF to get a (hopefully) balanced impression about the pros and cons.

Show me some proof

  • Krane, Jeffrey F., et al. "Synergistic effects of epidermal growth factor (EGF) and insulin-like growth factor I/somatomedin C (IGF-I) on keratinocyte proliferation may be mediated by IGF-I transmodulation of the EGF receptor." Journal of investigative dermatology 96.4 (1991): 419-424.

Products with SH-Oligopeptide-2

Toskani Rcpr Manyo Factory 4Gf Eye Cream Eighth Day Regenerating Serum AnteAGE Overnight Brows Serum AnteAGE Overnight Lash Serum Be Minimalist Multi-Peptide Serum (7% Matrixyl 3000 + 3% Bio-Placenta) Catherine Jinn Age Gracefully Acure Radically Rejuvenating Whipped Night Cream Acure Radically Rejuvenating Whipped Night Cream Le Mieux 24 Hour Age Defying Cream Yuri Pibu Cellum Amaid Ampoule Drunk Elephant Protini™ Polypeptide Cream Isntree Egf Repair Cream Isntree Egf Repair Cream Kate Somerville Kx Active Concentrates Bio-Mimicking Peptides Serum Sidmool Min Jung Gi Efi Eye Cream Sidmool Royal Honey Peptide Deep Moisture Sleeping Pack Swanicoco Fermentation Peptine Eye Care Cream Neulii Cicapepta Repair Serum Neulii Cicapepta Repair Serum Sidmool Dr. Galatok Real Peptide Barrier Moisture Cream Colibri Cosmetics Hyaluron Konzentrat Murad Nutrient-Charged Water Gel Sidmool Madagascar Ultra Moisture Cream Nurse Jamie EGF Platinum 7 Rejuvenating Facial Cream Sidmool Bulgarian Rose Essential Sidmool Idebenone Elastic Ampoule Dr. Brandt Needles No More No More Baggage Plush Bio Contur Intensiv Ochi - Extract Proaspăt De Tei, Oligopeptide, Placentă Sculplla H2 Repair Sun Cushion Spf 50 MEDI-PEEL Naite Thread Neck Cream SeneGence Advanced Seneplex+® Renewal Serum With Retinol AnteAGE MD Serum AnteAGE Md Serum Lamelle Dermaheal Eye Regeneration Plus CELLBN 24K Gold Ampoule Set Natura Bissé Inhibit Exclusive High Definition Serum Saturday Skin Quench Intense Hydration Mask Saturday Skin Spotlight Brightening Mask Rude Serum Of Love Caolion Pore Deep Toner Isntree TW-Real Eye Cream MEDI-PEEL Mezzo Filla, Eye Serum Dr. G Revital Enhancer Emulsion Klairs Midnight Blue Calming Cream Klairs Midnight Blue Calming Cream Saturday Skin Balancing Act Skin-Smoothing Lotion dear Klairs Midnight Blue Calming Cream By Ecom Pure Calming Soothing Gel Cream Missha Super Aqua Cell Renew Snail Ampoule