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Acetyl Hexapeptide-8

Acetyl Hexapeptide-8

Also-called-like-this: Argireline, Acetyl Hexapeptide-3


If you see a cosmetic product that claims that it has "Botox-like effect" then two things are almost certain: one, the product overpromises and two, it contains Argireline. 

So this one is the famous peptide that's marketed by its manufacturer as the "Botox in a jar". The basis for this claim is that it targets the same wrinkle forming mechanism (wrinkles caused by facial muscle movement) as Botox, but the way it works is very different. In addition, the extent to which it can prevent muscles from contracting (and to smooth wrinkles) is very different (otherwise why would anyone use still Botox?). 

The manufacturer did several studies to prove that Argireline really works and it does (just not as well as Botox). In-vivo (made on real people) tests showed that using 10% Argireline solution around the eyes for 15 days decreased wrinkles depth by 17%, while a 5% Argireline formula applied for 28 days did almost the same with a decrease in wrinkle depth by 16.26%. A Spanish University also did some research and found that Argireline increased the level of skin moisturization and decreased both the depth and width of wrinkles "significantly". 

This means, Acetyl Hexapeptide-8 does have some ability to smooth wrinkles (but not as well as Botox - sorry, if we sound like a broken record). Also, we have to agree with TruthInAging, that it's not a collagen builder and not a preventer of structural aging (think vitamin C, AHAs or retinol); it's just a quick fix. If you are looking for one, this could be your thing. If you are more of a "let's treat this aging thing properly" type, then it's probably not your thing.

Show me some proof

  • Ruiz, M. A., et al. "Evaluation of the anti-wrinkle efficacy of cosmetic formulations with an anti-aging peptide (Argireline®)." Ars pharm 50.4 (2010): 168-176.
  • Wang, Yuan, et al. "The Anti-Wrinkle Efficacy of Argireline, a Synthetic Hexapeptide, in Chinese Subjects." American journal of clinical dermatology 14.2 (2013): 147-153.

Products with Acetyl Hexapeptide-8

Dew and Dew Luxury Cell Collagen Peptide Ampoule Scinic Peptide Ampoule 95 Sidmool Acetyl Ampoule Sidmool Min Jung Gi Efi Eye Cream Borghese Insta Form Platinum CELLBONE Hyper Peptides CRL Peptide Aqua Gel Mask DMK Eye Tone Derm Institute Youth Alchemy Eye Cream Dr's Secret Eye Cream Foresta Pore And Whitening Serum Gravity Skincare 1All™ Serum Her Hyness Bio-peptide Advanced Youth Plus Glow Serum Hyalogic Episilk, Facial Relax Face Serum Image Skincare The Max™ Stem Cell Serum Kirkland Signature Borghese Insta-Firm Platinum Advanced Wrinkle Relaxer Le Mieux Bio Cell Rejuvenating Cream Le Mieux Bio Cell Rejuvenating Cream Le Mieux Bio Cell Rejuvenating Cream Le Mieux Essence Moisturizer Matte Renewal Serum NuGene Eye Serum Recover Antiaging Antiarrugas Intensivo Sharova Pro Anti-wrinkle Facial Line Cream Skin1765 Repair Skinwell Derm (Dr. Ava Khosraviani) Total Eye Spa Salonnepro Anti-aging Serum Suiphar Peptix Summer Fridays Light Aura Vitamin C + Peptide Eye Cream The Skin Collection Argireline 10% The Skin Collection Serum Argireline 10% Theraderm Eternox Peptide Creme TiN5 The Youth Booster Trish McEvoy Instant Solutions Triangle Of Light Eye Mask Trish McEvoy Trish McEvoy Beauty Booster Serum Umoua Advanced Extraction Liposome Tech Peptide Renewal Cream V Magic Magic V Pre-Serum (V-Serum) iQ Natural Line Reducing - Argireline Serum the NewLab. 10% Argireline + Copper Peptide Serum trish mcavoy Beauty Booster® Eye Serum By Trish McEvoy AQ Skin Solutions Eye Serum Aurelia Serum Superhidratante Avya Anti-aging Power Serum Bellirium Serum Botox-Like Complex Bioelements Power Peptide BiteCoCo Redness Neutralizing Color Correcting Cream CeraCode Anti Aging Barrier Serum ClearChoice Age Defying Moisturizer With Clinical Repair Dermexcel Retinol Serum Ecooking Day Cream