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A four amino acid (Glycine – Glutamic acid – Lysine – Glycine) peptide that belongs to the group of signal peptides that mimic skin-protein breakdown products to trick the skin into creating some nice new skin proteins, such as collagen (if this sentence is not clear, here is a bit longer and nicer explanation). 

According to its manufacturer, Tetrapeptide-21 shows superior collagen, hyaluronic acid and fibronectin (all nice and important skin elements) boosting activity, and can smooth and minimize all kinds of wrinkles. Their in-vivo (made on real people) tests confirmed that the peptide improves skin elasticity after 8 weeks of use, and they also have some nice before and after pictures showing visible-to-the-naked-eye wrinkle reduction around the eye area. 

Products with Tetrapeptide-21

Perricone MD No:Rinse Intensive Pore Minimizing Toner TAHNYC Contour Concentrated 10 Peptide Serum NeoCutis Micro Gel Seratopical Revolution Adoring Advanced Eye Formulation Serum TAHNYC Complex B5 ISOMERS Skincare Glutathiosome Booster ISOMERS Skincare Ultimate Super Skin Booster Vials Cyberderm H2O Hydration Pearlessence Retinol + Collagen Truefitt & Hill Authentic No. 10 Sensitive Moisturiser TAHNYC Illume Dr Dennis Gross Triple C Firming Peptide Oil NeoCutis Bio Serum Firm Peter Thomas Roth Un-Wrinkle Turbo Line Smoothing Toning Lotion Beauty Counter Countertime Tetrapeptide Supreme Cream Dr Dennis Gross Firming Peptide Milk Dr Dennis Gross Hydra-Pure Oil-Free Moisturiser Isomers All-In-One The Cream NeoCutis Micro Night Pearlessence Works Like Magic | All-in-one Cream ACO Face Anti Age 40+ Lift & Fill Hydrating Serum ACO Face Age Delay Night Cream Normal Skin NeoCutis Biocream Firm ACO Face Anti Age 40+ Lift & Fill Night Cream Normal Skin Algenist Concentrated Reconstruting Serum Azarine Revitalizing Anti Aging Serum Biodermal Anti age 40+ night cream Cliniderm Age Correct Day Cream Medik8 Liquid Peptides Rodan + Fields Restorative Lotion ACO Face Anti Age 40+ Lift & Fill Firming Eye Cream Algenist Power Advanced Wrinkle Fighter Serum Cliniderm by ACO Cliniderm Age Correct Night Cream Eubos IN A SECOND Wow Now Lift Boost Melina Organics Intimate Whitening Gel NeoCutis Micro Day NeoCutis Micro Serum NeoCutis Neo Firm Neck & Decollete Tightening Cream Rodan + Fields Redefine Triple Defense Treatment Spf 30 Zo skin health Hydrating Creme ACO Face Anti Age 40+ Lift & Fill Day Cream Normal Skin Spf15 Algenist Regenerative Anti-Aging Moisturizer Biodermal Anti age 40+ day cream Biodermal Anti age 50+ day cream NeoCutis Lumière® Firm Riche Extra Moisturizing Illuminating Tightening Eye Cream NeoCutis Micro Eyes By Lumiere - Tightening Cream ACO Anti-Age Filling Night Cream Dry Skin Biodermal Anti age 50+ night cream Dr Dennis Gross Ferulic + Retinol Triple Correction Eye Serum ACO Age Delay Night Dry Skin