Follow us on our new Insta page »


Also-called-like-this: Acidic Fibroblast growth factor, FGF1, rh-Polypeptide-11


Sh-Polypeptide-11 is a medium sized cell signaling molecule also called Acidic Fibroblast Growth Factor. It belongs to the same group of ingredients (Growth Factors) as its better-known sister, Epidermal Growth Factor or Sh-Oligopeptide-1. As its name suggests, FGF can stimulate the growth and proliferation of fibroblast cells (VIP cells that produce among other things collagen). According to manufacturer info, it also stimulates skin regeneration, wound healing and collagen and elastin synthesis. 

As for research, we could find an in-vitro study that proved that "Recombinant FGF-1 strongly stimulated fibroblast and keratinocyte proliferation. However, the transition of this protein through the SC required an appropriate carrier system - lipid spheres." 

It's also good to know that slathering mitogenic (= stimulates cell proliferation) ingredients on yourself is somewhat controversial. If you are new to the "Growth Factors and skincare" topic, we have a more detailed explanation of Epidermal Growth Factor, so click here and read all about it.

Show me some proof

  • Żerańska, Justyna, et al. "A study of the activity and effectiveness of recombinant fibroblast growth factor (Q40P/S47I/H93G rFGF-1) in anti-aging treatment." Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii 33.1 (2016): 28.

Products with SH-Polypeptide-11

Eighth Day Regenerating Serum AnteAGE Overnight Brows Serum AnteAGE Overnight Lash Serum Caolion P-Tox® Recovery Essence Interfarmac s.r.l. Remize Siero Be Minimalist Multi-Peptide Serum (7% Matrixyl 3000 + 3% Bio-Placenta) Catherine Jinn Age Gracefully Sidmool Min Jung Gi Efi Eye Cream Sidmool Royal Honey Peptide Deep Moisture Sleeping Pack Swanicoco Fermentation Peptine Eye Care Cream Acure Radically Rejuvenating Whipped Night Cream Acure Radically Rejuvenating Whipped Night Cream Sidmool Dr. Galatok Real Peptide Barrier Moisture Cream Sidmool Dr. Galatok Galatokside Real N.M.F Barrier Serum Drunk Elephant Protini™ Polypeptide Cream Kate Somerville Kx Active Concentrates Bio-Mimicking Peptides Serum Sidmool Bulgarian Rose Essential Sidmool Madagascar Ultra Moisture Cream Colibri Cosmetics Hyaluron Konzentrat Neulii Cicapepta Repair Serum Murad Nutrient-Charged Water Gel Sidmool Idebenone Elastic Ampoule Nurse Jamie EGF Platinum 7 Rejuvenating Facial Cream BONAJOUR Elf Skin (Toner) Dr. Brandt Needles No More No More Baggage SeneGence Advanced Seneplex+® Renewal Serum With Retinol CELLBN 24K Gold Ampoule Set Rude Serum Of Love Caolion Pore Deep Toner Natura Bissé Inhibit Exclusive High Definition Serum Soroci Spot-Light Eye Cream RevivSerums Telomerase Serum Klairs Midnight Blue Calming Cream Klairs Midnight Blue Calming Cream dear Klairs Midnight Blue Calming Cream Sensilis Origin Pro Egf-5 Cream MEDI-PEEL Bio Intense Gluthione 600 White Ampoule Klairs Freshly Juiced Vitamin C Serum dear Klairs Freshly Juiced Vitamin Drop Bondichic Four Seasons Envi Hydrating Moisturiser-Night Caolion P-Tox® Neck Recovery Cream AHC Pepta Active Real Eye Cream For Face AHC Ageless Real Eye Cream For Face AHC Time Rewind Real Eye Cream For Face