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Also-called-like-this: Acidic Fibroblast growth factor, FGF1, rh-Polypeptide-11

Official CosIng Information


Sh-Polypeptide-11 is a medium sized cell signaling molecule also called Acidic Fibroblast Growth Factor. It belongs to the same group of ingredients (Growth Factors) as its better-known sister, Epidermal Growth Factor or Sh-Oligopeptide-1. As its name suggests, FGF can stimulate the growth and proliferation of fibroblast cells (VIP cells that produce among other things collagen). According to manufacturer info, it also stimulates skin regeneration, wound healing and collagen and elastin synthesis. 

As for research, we could find an in-vitro study that proved that "Recombinant FGF-1 strongly stimulated fibroblast and keratinocyte proliferation. However, the transition of this protein through the SC required an appropriate carrier system - lipid spheres." 

It's also good to know that slathering mitogenic (= stimulates cell proliferation) ingredients on yourself is somewhat controversial. If you are new to the "Growth Factors and skincare" topic, we have a more detailed explanation of Epidermal Growth Factor, so click here and read all about it.

Show me some proof

  • Żerańska, Justyna, et al. "A study of the activity and effectiveness of recombinant fibroblast growth factor (Q40P/S47I/H93G rFGF-1) in anti-aging treatment." Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii 33.1 (2016): 28.

Products with SH-Polypeptide-11