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Serious Skincare Pure Pep Creme Riche

Serious Skincare
Pure Pep Creme Riche

The 30% Peptide and Neuropeptide cream helps to minimize the appearance of wrinkles and lines for a softer, smoother, younger look and texture
Uploaded by: incieolder on 26/01/2019

Highlights

#alcohol-free
Alcohol Free

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Skim through

Ingredient name what-it-does irr., com. ID-Rating
Water solvent
Acetyl Octapeptide-3 cell-communicating ingredient, moisturizer/​humectant goodie
Caprylic/Capric Triglyceride emollient
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters emulsifying, surfactant/​cleansing
Glyceryl Stearate emollient, emulsifying 0, 1-2
Cetearyl Alcohol emollient, viscosity controlling 1, 2
Sodium Stearoyl Lactylate emulsifying
Palmitoyl Dipeptide-10
Palmitoyl Oligopeptide cell-communicating ingredient goodie
Tetrapeptide-14 cell-communicating ingredient, soothing goodie
Glyceryl Polymethacrylate viscosity controlling
Propylene Glycol moisturizer/​humectant, solvent 0, 0
Octyldodecyl Myristate emollient
Butylene Glycol moisturizer/​humectant, solvent 0, 1
Camellia Sinensis (Tea) Extract antioxidant, soothing, antimicrobial/​antibacterial superstar
Aspalathus Linearis (Rooibos) Extract
Boswellia Serrata Extract soothing
Honey Extract moisturizer/​humectant goodie
Phenoxyethanol preservative
Sodium Benzoate preservative
Dicaprylyl Ether emollient, solvent
Hydrogenated Palm Kernel Glycerides emollient, viscosity controlling
Hydrogenated Palm Glycerides emollient, emulsifying, viscosity controlling
Tetrapeptide-21 cell-communicating ingredient goodie
Tripeptide-1 cell-communicating ingredient goodie
Tetrapeptide-7
Cetyl Alcohol emollient, emulsifying, viscosity controlling 2, 2
Palmitoyl Urea
Glucose moisturizer/​humectant goodie
Guanidine Hcl buffering
Magnesium Aluminum Silicate viscosity controlling 0, 0
Acetyl Tetrapeptide-17
Colloidal Platinum antimicrobial/​antibacterial, antioxidant
Bakuchiol cell-communicating ingredient goodie
Acetyl Glucosamine skin-identical ingredient, skin brightening goodie
Ethylhexylglycerin preservative
Tocopheryl Acetate antioxidant 0, 0
Fragrance perfuming icky
Lactic Acid exfoliant, moisturizer/​humectant superstar
Xanthan Gum viscosity controlling
Caffeine antioxidant goodie
Disodium EDTA chelating
Methylisothiazolinone preservative icky
Sodium Hyaluronate skin-identical ingredient, moisturizer/​humectant 0, 0 goodie

Serious Skincare Pure Pep Creme Riche
Ingredients explained

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

Also-called: SNAP-8, Acetyl Glutamyl Heptapeptide-1 | What-it-does: cell-communicating ingredient, moisturizer/humectant

A newer and, molecule-wise, somewhat bigger version of the famous "Botox-like" peptide called Acetyl Hexapeptide-8 or Argireline. Just like Argireline, Acetyl Octapeptide-3 is also claimed to influence the muscle contraction process that results in a more relaxed and line-free face, especially around the forehead and the eyes.  

While Argireline counts as a pretty well-proven peptide, with multiple studies confirming its anti-wrinkle efficacy, we cannot say the same for Acetyl Octapeptide-3. What we have is the manufacturer's claim that comparing 10% Argireline with 10% SNAP-8 solution (that means 0.005% pure peptide powder) the SNAP-8 peptide did a bit better as it reduced wrinkles by 34.98% vs 27.05% reduction for Argireline (twice a day use for 28 days on 17 women). 

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Other than that, we can write here pretty much the same as at Argireline. Obviously, no peptide works as effectively as real Botox, and the Botox-inspired peptides are quick fixes rather than being collagen builders or real preventers of structural aging. They are nice additions to an anti-aging skincare routine but not the real superstars (think vitamin CAHAs or retinol).

What-it-does: emollient

A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, and it’s also easy to formulate with. No wonder it’s popular. 

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot)
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

A natural emulsifier that helps oil and water to nicely mix together. It is claimed to bring a silicone-feel to natural formulations and to give an ultra-soft texture and cushion touch

It is a natural wax derivative (from rice bran, candelilla, and jojoba waxes) that also has some moisturizing properties as it can retain 6 times its own weight in water, forming a water cushion on the skin.

What-it-does: emollient, emulsifying | Irritancy: 0 | Comedogenicity: 1-2

A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.

Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.

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It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".

What-it-does: emollient, viscosity controlling | Irritancy: 1 | Comedogenicity: 2

An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.  

It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols.  Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.

What-it-does: emulsifying

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Also-called: Biopeptide El, pal-VGVAPG, Palmitoyl Oligopeptide (old name);Palmitoyl Hexapeptide-12 | What-it-does: cell-communicating ingredient

A six amino acid peptide that is claimed to improve firmness and skin tone. Its amino acid sequence is Val-Gly-Val-Ala-Pro-Gly that is also called the "spring fragment" and is repeated six times in the important skin protein, elastin molecule.

The manufacturer made a double-blind, one-month long clinical study on 10 women and found that twice a day application of 4%  Biopeptide El improved skin firmness by 33% and skin tone by 20%. 

A peptide designed by a small company (Helix Biomedix) specializing in developing small proteins aka bioactive-peptides. Tetrapeptide-14 is claimed to be a soothing, redness reducing peptide that works by down-regulating a pro-inflammatory signal molecule (called interleukon-6) to prevent inflammation.

The peptide is combined with plant extracts (green tea, boswellia) and honey and is sold under the trade name Granactive AR-1423. According to the manufacturer of the complex, 5% of the active reduced rosacea associated redness by 50% over a 4 weeks study.

What-it-does: viscosity controlling

We don't have description for this ingredient yet.

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 0
  • It's a helper ingredient that improves the freeze-thaw stability of products
  • It's also a solvent, humectant and to some extent a penetration enhancer
  • It has a bad reputation among natural cosmetics advocates but cosmetic scientists and toxicology experts do not agree (read more in the geeky details section)
Read all the geeky details about Propylene Glycol here >>

What-it-does: emollient

We don't have description for this ingredient yet.

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

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It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive. 

Also-called: Green Tea;Camellia Sinensis Leaf Extract | What-it-does: antioxidant, soothing, antimicrobial/antibacterial
  • Green tea is one of the most researched natural ingredients
  • The active parts are called polyphenols, or more precisely catechins (EGCG being the most abundant and most active catechin)
  • There can be huge quality differences between green tea extracts. The good ones contain 50-90% catechins (and often make the product brown and give it a distinctive smell)
  • Green tea is proven to be a great antioxidant, UV protectant, anti-inflammatory, anticarcinogenic and antimicrobial
  • Because of these awesome properties green tea is a great choice for anti-aging and also for skin diseases including rosacea, acne and atopic dermatitis
Read all the geeky details about Camellia Sinensis Leaf Extract here >>

We don't have description for this ingredient yet.

Also-called: Indian Frankincense Extract | What-it-does: soothing

The extract coming from the Indian Frankincense, a medium-sized tree native to India. Mostly the gum-resin is used that is obtained from an incision made on the trunk of the tree.  It contains about 30-60% resin, 5-10% fragrant essential oil,  and the rest is made up of polysaccharides (mostly arabinose, galactose, xylose).

The biologically most active components of the resin are boswellic acids that have anti-inflammatory propertiesAccording to manufacturer info, the boswellic acids rich resin extract is also a potent inhibitor of elastase (an enzyme that breaks down proteins, including collagen) and has antiGAGase activity (protecting the important natural moisturizing factors, glycosaminoglycans in the skin) meaning that it can help the skin to stay firm for a longer time.

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The reason why we did not award Boswellia Serrata Extract a goodie status is that this INCI name is not clear enough on the type of the extract. It might be a boswellic acids rich, anti-inflammatory extract (that is a goodie) or it might be a fragrant essential oil rich extract used in perfumery or aromatherapy that can be a problem for sensitive skin types. 

Honey Extract - goodie
What-it-does: moisturizer/humectant

Usually, a glycerin or glycol based extract of honey that has similar properties to pure honey, i.e. moisturizing, soothing and antibacterial magic properties.

If you wanna know more about honey in cosmetics, we have a shiny explanation here >>

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

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Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10). 

It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.

What-it-does: preservative

A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi. 

It’s pH dependent and works best at acidic pH levels (3-5). It’s not strong enough to be used in itself so it’s always combined with something else, often with potassium sorbate.

What-it-does: emollient, solvent

A clear, colorless and odorless oily liquid that works as a fast-spreading emollient with a dry skin feel

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

A four amino acid (Glycine – Glutamic acid – Lysine – Glycine) peptide that belongs to the group of signal peptides that mimic skin-protein breakdown products to trick the skin into creating some nice new skin proteins, such as collagen (if this sentence is not clear, here is a bit longer and nicer explanation). 

According to its manufacturer, Tetrapeptide-21 shows superior collagen, hyaluronic acid and fibronectin (all nice and important skin elements) boosting activity, and can smooth and minimize all kinds of wrinkles. Their in-vivo (made on real people) tests confirmed that the peptide improves skin elasticity after 8 weeks of use, and they also have some nice before and after pictures showing visible-to-the-naked-eye wrinkle reduction around the eye area. 

Tripeptide-1 - goodie
Also-called: GHK, Kollaren | What-it-does: cell-communicating ingredient

A small, three amino acid (glycine-histidine-lysine or GHK) peptide that is famous for being a type I collagen fragment. The theory behind collagen-fragment peptides is that when collagen naturally breaks down in the skin, the resulting peptide fragments signal to the skin that it should get to work and create some nice, new collagen.

Adding in collagen fragment peptides, like GHK, might trick the skin into thinking that collagen has broken down and it's time to create some more. So Tripeptide-1 is believed to be able to stimulate collagen production in the skin, and more collagen means fewer wrinkles and younger looking skin. FYI; Tripeptide-1 is the same peptide that can be found in the famous Matrixyl 3000, but in Matrixyl a palmitic acid is attached to it to increase its oil solubility and thus skin penetration.

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Another reason why Tripeptide-1 is especially famous is that it is not only a signal peptide but also a so-called carrier peptide that helps to stabilize and deliver copper in the skin. It has a high affinity for copper ions and likes to form a complex with them called Copper-Tripeptide-1 or GHK-Cu. GHK-Cu is a famous and well-researched peptide that does a bunch of things in the skin and we have a shiny explanation about it here

As for Tripeptide-1 in and of itself, without a palmitic acid or copper attached to it, it goes by the trade name Kollaren and according to the manufacturer, it not only stimulates collagen but also other essential skin proteins such as fibronectin, elastin, and laminin. Kollaren is also claimed to be beneficial for acne-prone skin as it can boost tissue repair and thus help acne scars to heal faster. 

We don't have description for this ingredient yet.

What-it-does: emollient, emulsifying, viscosity controlling | Irritancy: 2 | Comedogenicity: 2

A so-called fatty (the good, non-drying kind of) alcohol that does all kinds of things in a skincare product: it makes your skin feel smooth and nice (emollient), helps to thicken up products and also helps water and oil to blend (emulsifier). Can be derived from coconut or palm kernel oil.

This ingredient name is not according to the INCI-standard. :( What, why?!

Glucose - goodie
What-it-does: moisturizer/humectant

A fancy name for sugar. Luckily when you put it on your skin it's good for you not like when you eat it. :) It has water-binding properties, which means that it helps to keep your skin nice and hydrated

What-it-does: buffering

We don't have description for this ingredient yet.

What-it-does: viscosity controlling, absorbent/mattifier | Irritancy: 0 | Comedogenicity: 0

A type of clay mineral that works as a nice helper ingredient to thicken and stabilize formulas. As a clay, it consists of platelets that have a negative charge on the surface (face) and a positive on the edge. So the face of one platelet attracts the edge of the other and this builds a so-called "house of card" structure meaning that Magnesium Aluminum Silicate (MAS) thickens up products and helps to suspend non-soluble particles such as color pigments or inorganic sunscreens (zinc oxide and titanium dioxide).

As the "house of card" structure takes some time to form but collapses quickly if the formula is stirred, products thickened with MAS can be thick in the jar but become easily spreadable upon application (called thixotropy). MAS also gives nice sensory properties, it is not tacky or sticky and gives a rich, creamy skin feel. Also a good team player and works in synergy with other thickeners such as Cellulose Gum or Xanthan Gum

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Bakuchiol - goodie
Also-called: Sytenol A, Phyto Retinol | What-it-does: cell-communicating ingredient

At first glance, you could think that Bakuchiol is your average plant extract. It is derived from the seeds of Psoralea Corylifolia, aka Babchi, a plant important in Indian and Chinese medicine. The molecule was first isolated in 1973 and several anti-something properties are known about it: it has anti-inflammatory, antioxidant, anti-tumor, anti-bacterial and hepatoprotective magical abilities like plenty of other Ayurvedic plant extracts.

What makes Bakuchiol a special snowflake is the recent discovery that it behaves on the skin in a way very similar to well-known skincare superstar, retinol. While chemically, it has nothing to do with the vitamin-A family, aka retinoids, comparative gene expression profiling (a fancy way of saying that they compared how retinol and bakuchiol modify the way  skin cells behave and produce important skin proteins such as collagen) shows that retinol and bakuchiol regulate skin cell behavior in a similar way. 

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To be more specific, both Bakuchiol and retinol upregulate collagen I, III and IV production and downregulate MMP, the evil collagen attacking enzyme in our skin. This means more collagen stays in our skin and we all know that more collagen equals firmer, more wrinkle-free skin.  A 12-week clinical study using a 0.5% Bakuchiol formula with 17 people using it twice a day confirmed a significant improvement in lines and wrinkles, elasticity, firmness and an overall reduction in photo-damage. Also, the test formula was very well tolerated, without any retinol-like side effects. 

What's more, a 2018 double-blind study with 44 people compared 0.5% Bakuchiol with 0.5% retinol cream and found that "bakuchiol is comparable to retinol in its ability to improve photoaging and is better tolerated than retinol". A super promising result after 12 weeks. 

If you are not a daredevil-type who doesn't want to stop using a super well-proven retinol for a newbie like Bakuchiol, we have good news. The two also work very nicely together and Bakuchiol can actually help to stabilize the otherwise unstable and hard to formulate retinol.

And we are still not done, as Bakuchiol shows not only anti-aging properties but also nice anti-acne effects. 1% Bakuchiol seems to be very effective in itself (57% reduction in acne after 6 weeks treatment) and even better when combined with 2% salicylic acid (67% reduction in acne after 6 weeks). We like that Bakuchiol is such a good team player!  The molecule works against acne in multiple ways: It downregulates 5α-reductase (a sebum-controlling enzyme), it is antibacterial (including P. acnes), anti-inflammatory and it inhibits lipid-peroxidation, an evil oxidative process that is recently thought to be a very early trigger in the acne process. 

We feel that this description is becoming very long so we will just mention that Bakuchiol also seems to positively regulate hydration-related genes such as Aquaporin 3 and also shows some melanin-inhibiting properties

Overall, we think Bakuchiol is an awesome molecule with lots of promise both for anti-aging and anti-acne. But the proof compared to the well-established superstars is far from solid, so in a skincare routine, we would rather add Bakuchiol next to retinol than straight up replace it. Unless you are a gimme-the-newest-shiny-thing-under-the-sun-type. 

An amino acid sugar that can be found in the skin and does there good and important things. One of them is that it's a precursor for the biosynthesis of superstar moisturizer, hyaluronic acid. So acetyl glucosamine itself is also an important skin-identical ingredient and natural moisturizing factor.

But that is not all, acetyl glucosamine has two other great properties proved by double-blind clinical trials. First, it's a promising ingredient against wrinkles:  2% can improve wrinkles, particularly in the eye area.

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Second, the same amount can also fade - always stubborn - brown spots. (Do not expect magic, though - the photos from the study show the difference after 8 weeks of daily use. The difference is visible, but not that big. It's always good to have realistic expectations. :))  Combined with skincare superstar niacinamide the duo is synergistic and is more effective at improving hyperpigmentation, so if you are after the skin-lightening benefit look out for products that contain both. 

What-it-does: preservative

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient

Also-called: Vitamin E Acetate | What-it-does: antioxidant | Irritancy: 0 | Comedogenicity: 0

It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version. 

According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E. 

Fragrance - icky
Also-called: Fragrance, Parfum;Parfum/Fragrance | What-it-does: perfuming

Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!). 

If you are someone who likes to know what you put on your face than fragrance is not your best friend - no way to know what’s really in it.  

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Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!). 

Lactic Acid - superstar
  • It’s the second most researched AHA after glycolic acid
  • It gently lifts off dead skin cells to reveal newer, fresher, smoother skin
  • It also has amazing skin hydrating properties
  • In higher concentration (10% and up) it improves skin firmness, thickness and wrinkles
  • Choose a product where you know the concentration and pH value because these two greatly influence effectiveness
  • Don’t forget to use your sunscreen (in any case but especially so next to an AHA product)
Read all the geeky details about Lactic Acid here >>

It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little of xanthan gum will make it more gel-like.  Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). 

Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415). 

Caffeine - goodie
What-it-does: antioxidant

Hello, our favorite molecule that helps us wake up in the morning and then keeps us going through the day. As a super well-known stimulant from coffee, tea and plenty of other soft drinks, Caffeine needs no introduction. So we will skip right to the part where we talk about what the hell it does in so-so many cosmetic products.

Looking at the research, we were surprised to find how versatile Caffeine is. It is a small, water-loving molecule with pretty good skin penetration abilties. Once in the skin, it has nice antioxidant properties, meaning that it reduces the formation of evil free radicals and it might even be useful in preventing UV-induced skin cancers. 

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A well-known thing about Caffeine is that it improves the microcirculation of the blood vessels. Though conventional wisdom and anecdotal evidence says that this property is helpful for dark under-eye circles and puffy eyes, we have to mention that the double-blind research we have found about a 3% caffeine gel concluded that "the overall efficacy of the selected caffeine gel in reducing puffy eyes was not significantly different from that of its gel base."  But you know, the proof is in the pudding.

Another thing Caffeine is used for in body care products is its anti-cellulite effects. In theory, it can speed up the lipolysis process (the "fat burning"  by our cells) and stimulate the draining lymph system that might lead to the improvement of cellulite. But here again, the evidence that it actually makes a measurable, let alone visible,  improvement on actual human beings is limited (we could find only some animal skin studies or caffeine being combined with other actives). 

Last, but not least, we have to write about caffeine and hair growth. The theory is that it can inhibit the activity of the 5-α-reductase enzyme that plays an important role in hair loss and allows a renewed growth phase of the hair. We have found some recent and promising research to back this up. A 2017 study compared a 0.2% caffeine liquid with a 5% Minoxidil  (an FDA approved active to treat baldness) solution and found that  "a caffeine-based topical liquid should be considered as not inferior to minoxidil 5% solution in men with androgenetic alopecia", or English translation means that the caffeine liquid was pretty much as good as the FDA-approved Minoxidil stuff. Not bad!

Overall, we think that caffeine is a very versatile and biologically active ingredient. Even though some of its effects are more hyped up than backed up, it is still a nice to have on many ingredient lists. 

What-it-does: chelating

Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.

What-it-does: preservative

As you may guess, if something is only recommended in products that you rinse off (cleansers and shampoos), then it’s probably not the best ingredient for the skin.

Methylisothiazolinone (MI) is a preservative that' super efficient against bacteria at surprisingly low concentrations. The problem with it though is that it can also sensitize and irritate the skin quite easily when it comes in leave-on formulas.

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Currently, some countries are considering to ban it entirely (like Denmark) and the permitted use level is very low (under 0.01%). Luckily there are plenty of products on the market with other preservative options so if you are a better safe than sorry type it's probably best to avoid it. 

What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It’s the - sodium form - cousin of the famous NMFhyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

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In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).

What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists. 

If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does cell-communicating ingredient | moisturizer/humectant
A newer and molecule-wise somewhat bigger version of famous "Botox-like" peptide, Argireline. It is also claimed to influence the muscle contraction process that results in a more relaxed and line-free face. [more]
what‑it‑does emollient
A very common emollient that makes your skin feel nice and smooth. Comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
what‑it‑does emulsifying | surfactant/cleansing
A natural emulsifier that helps oil and water to nicely mix together. It is claimed to bring a silicone-feel to natural formulations and to give an ultra-soft texture and cushion touch. It is a natural wax derivative (from rice bran, candelilla, and jojoba waxes) that also has some moisturizing properties as it can retain 6 times its own weight in water, forming a water cus [more]
what‑it‑does emollient | emulsifying
irritancy, com. 0, 1-2
Waxy, white, solid stuff that helps water and oil to mix together and leaves the skin feeling soft and smooth. [more]
what‑it‑does emollient | viscosity controlling
irritancy, com. 1, 2
A super common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams. [more]
what‑it‑does emulsifying
what‑it‑does cell-communicating ingredient
Biopeptide El - A six amino acid peptide that is claimed to improve firmness (by 33% in one month) and skin tone (by 20%). [more]
what‑it‑does cell-communicating ingredient | soothing
A soothing, redness reducing peptide that works by down-regulating a pro-inflammatory signal molecule (called interleukon-6) to prevent inflammation. [more]
what‑it‑does viscosity controlling
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0, 0
A common glycol that improves the freeze-thaw stability of products. It's also a solvent, humectant and to some extent a penetration enhancer. [more]
what‑it‑does emollient
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0, 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
what‑it‑does antioxidant | soothing | antimicrobial/antibacterial
Green Tea - one of the most researched natural ingredients that contains the superstar actives called catechins. It has proven antioxidant, anti-inflammatory, antimicrobial and anticarcinogenic properties. [more]
what‑it‑does soothing
The extract coming from the Indian Frankincense - usually the gum resin is used that contains boswellic acid, a potent anti-inflammatory agent. Might also contain fragrant essential oils (depending on the type of the extract). [more]
what‑it‑does moisturizer/humectant
Usually, a glycerin or glycol based extract of honey that has similar properties to pure honey, i.e. moisturizing, soothing and antibacterial magic properties.If you wanna know more about honey in cosmetics, we have a shiny explanation here >> [more]
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
what‑it‑does preservative
A preservative that works mainly against fungi. Has to be combined with other preservatives. [more]
what‑it‑does emollient | solvent
A clear, colorless and odorless oily liquid that works as a fast-spreading emollient with a dry skin feel. 
what‑it‑does emollient | viscosity controlling
what‑it‑does emollient | emulsifying | viscosity controlling
what‑it‑does cell-communicating ingredient
A four amino acid (Glycine – Glutamic acid – Lysine – Glycine) peptide that belongs to the group of signal peptides that mimic skin-protein breakdown products to trick the skin into creating some nice new skin proteins, such as collagen (if this sentence is not clear, here is a bit longer and nicer explanation). [more]
what‑it‑does cell-communicating ingredient
A small, three amino acid (glycine-histidine-lysine or GHK) peptide that is famous for being a type I collagen fragment. The theory behind collagen-fragment peptides is that when collagen naturally breaks down in the skin, the resulting peptide fragments signal to the skin that it should get to work and create some nice, new collagen. [more]
what‑it‑does emollient | emulsifying | viscosity controlling
irritancy, com. 2, 2
A fatty (the good, non-drying kind of) alcohol that makes your skin feel smooth and nice (emollient), helps to thicken up products and also helps water and oil to blend (emulsifier).
what‑it‑does moisturizer/humectant
Sugar - as a skincare ingredient it has water-binding properties, which means that it helps to keep your skin nice and hydrated.  [more]
what‑it‑does buffering
what‑it‑does viscosity controlling
irritancy, com. 0, 0
A type of clay mineral that works as a nice helper ingredient to thicken and stabilize formulas. As a clay, it consists of platelets that have a negative charge on the surface (face) and a positive on the edge. [more]
what‑it‑does antimicrobial/antibacterial | antioxidant
what‑it‑does cell-communicating ingredient
At first glance, you could think that Bakuchiol is your average plant extract. It is derived from the seeds of Psoralea Corylifolia, aka Babchi, a plant important in Indian and Chinese medicine. [more]
what‑it‑does skin-identical ingredient | skin brightening
An amino sugar that helps the skin to stay hydrated, is also promising against wrinkles and can help to fade brown spots particularly when combined with niacinamide. [more]
what‑it‑does preservative
It can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too. [more]
what‑it‑does antioxidant
irritancy, com. 0, 0
A form of vitamin E that works as an antioxidant. Compared to the pure form it's more stable, has longer shelf life, but it's also more poorly absorbed by the skin. [more]
what‑it‑does perfuming
The generic term for nice smelling stuff put into cosmetic products so that the end product also smells nice. It is made up of 30 to 50 chemicals on average. [more]
what‑it‑does exfoliant | moisturizer/humectant
A superstar AHA that not only exfoliates skin but is also a very good moisturizer. In higher concentration (10% and up) it can even improve skin firmness, thickness, and wrinkles. [more]
what‑it‑does viscosity controlling
A super commonly used thickener and emulsion stabilizer. [more]
what‑it‑does antioxidant
The well-known stimulant from coffee. It has nice antioxidant properties and can improve the microcirculation. Might be helpful for dark circles, puffy eyes, as well as cellulite and hair loss. [more]
what‑it‑does chelating
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. [more]
what‑it‑does preservative
Preservative with relatively high irritation risk that is used mainly in rinse-off products. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]