BioHeal BOH

Probioderm Collagen Essence Sun Cream

A nice, multi-functional helper ingredient that's especially useful in sunscreens. It can solubilize some commonly used UV-filters like Oxybenzone or Avobenzone and it can also help to increase the SPF rating of sunscreens. It's also cosmetically elegant, has excellent spreadability and a pleasant, moisturizing skin feel. Oh, and according to Wikipedia, it even helps to stabilize famously unstable UVA-filter, Avobenzone.

Ethylhexyl Triazone is a new generation, chemical sunscreen (not available in the US due to impossible FDA regulations) that gives the highest photo-stable absorption of all available UVB filters today. It protects in the UVB range (280-320nm) with a peak protection of 314nm. It is an oil soluble, odorless, colorless powder that works well in fragrance-free formulas. It can be used up to 5% worldwide except for the US and Canada.

A  L'Oréal-group exclusive sunscreen agent commonly called Mexoryl SX. As opposed to most sunscreen agents, it is water soluble and protects in the UVA range with a peak absorbance at 345 nm. 

Its INCI name is a bit of a mouthful, but Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine is worth recognizing it as it is one of the best sunscreen agents known today. Unfortunately, it's not FDA-approved so you will not find it in sunscreens coming from the US (not because it's not good, but because US regulations make it impossible for newer sunscreen agents to get approved), but it is widely available in other parts of the world like Europe, Australia or Asia. 

It is a broad-spectrum (covers the whole UVB and UVA range, 280-400 nm) chemical sunscreen agent with peak protections at about 310 and 345 nm and unlike older UV filters, it's very photostable. It hardly deteriorates in the presence of UV light and it's also useful in stabilizing other less stable sunscreen agents, like the famous UVA protector, avobenzone.

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• A multi-functional skincare superstar with several proven benefits for the skin
• Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
• Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
• Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
• Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis

It's a little helper ingredient that helps to set the pH of the products to be right. It has an alkaline pH and can neutralize acidic ingredients.

A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives. 

Lactobacillus ferment is an interesting probiotic ingredient with some promising properties. 

First, according to a 2009 Estee Lauder patent, it’s a DNA repair enzyme and it can help to protect the skin against environmental aggressors.

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A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent and a broad spectrum antimicrobial. According to manufacturer info, it's also a moisturizer and helps to make the product feel great on the skin. It works synergistically with preservatives and helps to improve water-resistance of sunscreens. 

Diethylamino Hydroxybenzoyl Hexyl Benzoate is a new generation, chemical sunscreen agent (not available in the US due to impossible FDA regulations) that's designed for high UVA protection and high photostability. It gives sun protection in the whole UVA range (320-400 nm) with peak protection at 354nm. It can be used up to 10% worldwide except for the US and Canada. 

A silicone-based, chemical sunscreen agent that protects the skin in the UVB range (290-320 nm) with a peak absorbance at 312 nm. It is a colorless to pale yellow liquid with nice and non-shiny (at least compared to most other sunscreens) sensorial properties. 

It is a pretty good team player and can stabilize the famously unstable UVA filter, avobenzone and works especially well with Ensulizole to achieve high SPF protection. It is approved up to 10% as a sunscreen filter in the EU and most parts of the world, except for the United States. 

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Portulaca Oleracea is a nice succulent with bright yellow flowers and edible nutritious vegetables. It's a famous plant in Korean traditional medicine to treat infection and irritated skin.

Modern research confirms that it's loaded with skin-goodies: it's the richest green plant source of omega-3 fatty acids (α-linolenic acid), contains NMFs (polysaccharides and amino acids),  vitamins (β-carotene), minerals, and antioxidants (yellow betaxanthins and reddish betacyanins). Thanks to all its beneficial components, Purslane Extract has several magic properties: it's a great anti-inflammatory and antioxidant agent and also has wound healing abilities. 

We don't have description for this ingredient yet.

This awfully long named ingredient is, in fact, a pretty small molecule. It's a tripeptide (a three amino acid peptide)  with molecular weight less than 500 Da, meaning that it's small enough to penetrate nicely and easily into the skin.

It belongs to the "Botox in a jar" type of peptides (similar to Argireline or Leuphasyl) targeting wrinkles caused by facial movements, like laughter lines or crow’s feet. According to the manufacturer's in-vivo (made on real people) studies, 4% Syn-Ake used for 28 days resulted in 21% smoother and 15-20% less wrinkled skin with max values up to 52%. The smoothing effect was measurable on 80% of the volunteers, while the wrinkle reduction effect was evident on 73%.

If you see a cosmetic product that claims that it has "Botox-like effect" then two things are almost certain: one, the product overpromises and two, it contains Argireline. 

So this one is the famous peptide that's marketed by its manufacturer as the "Botox in a jar". The basis for this claim is that it targets the same wrinkle forming mechanism (wrinkles caused by facial muscle movement) as Botox, but the way it works is very different. In addition, the extent to which it can prevent muscles from contracting (and to smooth wrinkles) is very different (otherwise why would anyone use still Botox?). 

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• GHK-Cu is a copper-peptide complex found naturally in yucky bodily fluids (plasma, saliva, and urine)
• It has unique wound healing properties by stimulating the breakdown of unhealthy, too large collagen in scar tissue and stimulating nice and healthy collagen production afterwards
• It stimulates the production of several important skin-identical ingredients (e.g. collagen, elastin, and glycosaminoglycans)
• It has significant anti-inflammatory and antioxidant effect
• There are a few promising studies showing GHK-Cu can improve skin elasticity, clarity, firmness and reduce lines and wrinkles
• It can improve hair growth by enlarging hair follicles (and bigger follicles produce longer, thicker hair)
• There are some urban legends about possible overdosing or facial hair problems (read more in geeky details)

A small, three amino acid (glycine-histidine-lysine or GHK) peptide that is famous for being a type I collagen fragment. The theory behind collagen-fragment peptides is that when collagen naturally breaks down in the skin, the resulting peptide fragments signal to the skin that it should get to work and create some nice, new collagen.

Adding in collagen fragment peptides, like GHK, might trick the skin into thinking that collagen has broken down and it's time to create some more. So Tripeptide-1 is believed to be able to stimulate collagen production in the skin, and more collagen means fewer wrinkles and younger looking skin. FYI; Tripeptide-1 is the same peptide that can be found in the famous Matrixyl 3000, but in Matrixyl a palmitic acid is attached to it to increase its oil solubility and thus skin penetration.

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A four amino acid peptide with the amino sequence of glycine-glutamine-proline-arginine. It is attached to palmitic acid (a fatty acid)  to increase oil solubility and skin penetration. 

It works by reducing the production of the signal molecule, interleukin-6 (IL-6) which promotes inflammation in the skin and less inflammation means slower degradation of important things (like collagen) that results in younger looking skin for a longer time. 

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A really famous peptide that is part of Matrixyl 3000, the most sold peptide complex in the word. Before we go and find out what the big deal with Matrixyl 3000 is, let's just focus on Palmitoyl Tripeptide-1 itself for a bit.

It's a small three amino acid (they are the building blocks of all proteins) peptide with the amino sequence of glycine-histidine-lysine, or GHK. GHK is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration. 

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A tripeptide (three amino acids attached to each other: Lys-Val-Lys) that's claimed to protect and boost collagen and improve skin texture.

The manufacturer did an in-vivo (made on real people) study with 45 volunteers and found that used twice daily for 84 days 1% and 2.5% Syn-Coll reduces the appearance of wrinkles by 7 and 12% respectively. In another study (also by the manufacturer) with 33 female Chinese volunteers, 77% of the participants felt that Syn-Coll visibly improved the firmness and elasticity of the skin after 4 weeks. What's more, 60% of the participants also noticed a reduction in the look of the pore size also after 4 weeks of treatment. 

A pretty famous and better-researched peptide consisting of five amino acids (the building blocks of all proteins). It was created in a joint effort by the French ingredient supplier, Sederma and the cosmetics industry big shot, Procter&Gamble.

The amino acid sequence of the peptide is lysine–threonine–threonine–lysine–serine (KTTKS). Sometimes, it's also called collagen pentapeptide, as it's a subfragment of skin-structure-giving type I collagen. The KTTKS amino sequence is then attached for better oil solubility and skin penetration to palmitic acid and BOOM; we get Palmitoyl Pentapeptide-4. 

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A six amino acid peptide that is claimed to improve firmness and skin tone. Its amino acid sequence is Val-Gly-Val-Ala-Pro-Gly that is also called the "spring fragment" and is repeated six times in the important skin protein, elastin molecule.

The manufacturer made a double-blind, one-month long clinical study on 10 women and found that twice a day application of 4%  Biopeptide El improved skin firmness by 33% and skin tone by 20%. 

We don't have description for this ingredient yet.

An anti-aging peptide that can visibly reduce the length and depth of wrinkles, at least according to its manufacturer. In vitro (meaning it was done in the lab, not on real people) studies show that it enhances epidermal regeneration, collagen type I and III synthesis as well as the synthesis of other important skin proteins. 

A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.

Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.

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One of the many types of ceramides that can be found naturally in the upper layer of the skin. Ceramides make up about 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated. It works even better when combined with its pal, Ceramide 1.

We wrote way more about ceramides at ceramide 1, so click here to know more.

An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid). 

Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier. 

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We don't have description for this ingredient yet.

It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

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It's the chemically chopped up version of normal lecithin. Most often it's used to create liposomes and to coat and stabilize other ingredients. 

A sugar beet-derived amino acid derivative with nice skin protection and moisturization properties. Betaine's special thing is being an osmolyte, a molecule that helps to control cell-water balance.  It is also a natural osmoprotectant, meaning that it attracts water away from the protein surface and thus protects them from denaturation and increases their thermodynamic stability. 

It also gives sensorial benefits to the formula and when used in cleansers, it helps to make them milder and gentler. 

It's one of the important lipids that can be found naturally in the outer layer of the skin. About 25% of the goopy stuff between our skin cells consists of cholesterol. Together with ceramides and fatty acids, they play a vital role in having a healthy skin barrier and keeping the skin hydrated. 

Apart from being an important skin-identical ingredient, it's also an emollient and stabilizer. 

A biocompatible copolymer (a big molecule that consists of more than one type of building blocks) that has the same structure as important cell membrane ingredient, phospholipid. Polyquaternium-51 is a good skin moisturizer, leaves a silky, smooth feel on the skin and can help to reduce irritation caused by some not-so-nice ingredients (like surfactants).

Beta-Glucan is a nice big molecule composed of many smaller sugar molecules (called polysaccharide). It’s in the cell walls of yeast, some mushrooms, seaweeds, and cereals.

It’s a real goodie no matter if you eat it or put it on your face. Eating it is anti-diabetic, anti-cancer, and even lowers blood cholesterol. 

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• Primary fat-soluble antioxidant in our skin
• Significant photoprotection against UVB rays
• Vit C + Vit E work in synergy and provide great photoprotection
• Has emollient properties
• Easy to formulate, stable and relatively inexpensive

When you hear oatmeal, you probably think of breakfast, but the finely ground version of whole oat kernels, aka colloidal oatmeal, can do good things for your skin, especially if it's dry, itchy or prone to skin-rashes or eczema.

Oat is loaded with compounds good for the body, inside or outside, such as soothing agent beta-glucan (5%),  lipids (3-11%) including barrier repairing omega-3 and 6 fatty acids or phenolic antioxidant and anti-inflammatory agents (avenanthramides). 

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We don't have description for this ingredient yet.

Adenosine is an important little compound in our body that has a vital cell-signalling role. Research on smearing it on our face is also promising and shows so far a couple of things:

• It can help with wound healing
• It’s a good anti-inflammatory agent
• It might even help with skin’s own collagen production and improve skin firmness and elasticity
• It helps with barrier repair and protection
• It might be even useful for the hair helping with hair thickness and hair growth

• A natural moisturizer that’s also in our skin
• A super common, safe, effective and cheap molecule used for more than 50 years
• Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
• Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
• High-glycerin moisturizers are awesome for treating severely dry skin

Glyceryl stearate citrate is similar to the super common skincare ingredient glyceryl stearate, and is similarly used to help combine waters and oils (emulsifier) and to make your skin feel nice and soft (emollient). 

The main difference between glyceryl stearate citrate and its cousin glyceryl stearate is that this one has a citric acid molecule also attached to its glycerin. This makes it what chemists call a diacylglycerol, which is a fancy word for two acids (in this case, citric acid and stearic acid) attached together with a glycerin bridge. But when it comes to cosmetics, all you need to know is that both glyceryl stearate citrate and glyceryl stearate are safe, tried and true emulsifiers. Expect to see them in formulas with both water-based and oil-based ingredients (think moisturizers and lotions).

An oily kind of ingredient that can magically blend with water all by itself. This is called self-emulsifying and SE in its name stands for that.

The difference between "normal" Glyceryl Stearate and this guy is that the SE grade contains a small amount of water-loving soap molecules, such as sodium stearate. This increases Glyceryl Stearate's affinity for water and gives it stronger emulsifying abilities.    

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We don't have description for this ingredient yet.

A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula.  It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.

A kind of polymer (big molecule from repeated subunits) that helps to create beautiful gel-like textures. It's also a texturizer and thickener for oil-in-water emulsions. It gives products a good skin feel and does not make the formula tacky or sticky. 

It works over a wide pH range and is used between 0.5-1.2%.

A polymeric (big molecule from repeated subunits) emulsifier that comes from Inulin, a naturally occurring polysaccharide found in the roots and rhizomes of several plants. The emulsifier is obtained by adding oil-loving chains onto inulin. The resulting copolymer can emulsify high amounts of oil and can stabilize oil droplets or non-water soluble particles so that they do not clump together in the formula. 

Though its long name does not reveal it, this polymer molecule (big molecule from repeated subunits or monomers) is a relative to the super common, water-loving thickener, Carbomer. Both of them are big molecules that contain acrylic acid units, but Acrylates/C10-30 Alkyl Acrylate Crosspolymer also contains some other monomers that are hydrophobic, i.e. water-hating. 

This means that our molecule is part water- and part oil-loving, so it not only works as a thickener but also as an emulsion stabilizer. It is very common in gel-type formulas that also contain an oil-phase as well as in cleansers as it also works with most cleansing agents (unlike a lot of other thickeners). 

An amino acid-based emulsifier that helps water and oil to mix and stay that way. It is considered as natural, environmentally friendly, and hypoallergenic. 

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient. 

It's a type of glycol that - according to the manufacturer - is an extremely good replacement for other glycols like propylene or butylene glycol. Its main job is to be a solvent, but it has also very good antimicrobial properties and acts as a true preservative booster. Also helps with skin hydration without stickiness or tacky feel.

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A fatty alcohol (the non-drying type with a long oil loving chain of 22 carbon atoms) that is used to increase the viscosity of the formula and it also helps the oily and the watery parts to stay nicely mixed together (called emulsion stabilizing). 

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

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An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.  

It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols.  Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.

We don't have description for this ingredient yet.

Biosaccharide Gum-1 is a pretty interesting kind of sugar ingredient that is created from sorbitol via bacterial fermentation. 

According to the manufacturer it’s a “S.M.A.R.T.” sugar: it has Soothing, Moisturizing, Anti-aging, Restructuring and Touch properties. Let’s look at them quickly one by one.

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A naturally occurring fructose polysaccharide found in the roots and rhizomes of several plants, for example, chicory. It is used in skincare for its prebiotic activity, meaning that it reduces the growth of bad bacteria in favor of friendly microorganisms naturally present on the skin.