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Ceramide EOP

Ceramide EOP

Also-called-like-this: Ceramide 1


Ceramides get quite a lot of hype recently and good news: there is a reason for that. But before we go into the details, let's just quickly define what the heck ceramides are:

They are waxy lipids that can be found naturally in the outer layer of the skin (called stratum corneum - SC). And they are there in big amounts! The goopy stuff between our skin cells is called extracellular matrix that consists mainly of lipids. And ceramides are about 50% of those lipids (the other important ones are cholesterol with 25% and fatty acids with 15%). 

Ok, so now we know what ceramides are, let's see what they do in our skin: research shows clearly that they play a super important role in keeping the skin barrier healthy and the skin hydrated. If ceramides in the skin are decreased, more water can evaporate from the skin and there is less water remaining in the skin. So ceramides form kind of a "water-proof" protecting layer and make sure that our skin remains nice and hydrated. 

Now the question is only this: If we put ceramides all over our face do they work as well as ceramides already naturally in our skin? Well, the answer is probably a no, but they do work to some extent. The BeautyBrains blog made a fantastic article about ceramides and they have listed a couple of examples about studies showing that ceramides - especially when used in certain ratios with cholesterol and fatty acids  - do hydrate the skin and can help to repair the skin barrier.

So far we were writing about ceramides in plural. It's because there are lots of different ceramides, a 2014 article writes that currently 12 base classes of ceramides are known with over 340 specific species. Chemically speaking, ceramides are the connection of a fatty acid and a sphingoid base and both parts can have different variations that result in the different types of ceramides. 

Our current one, Ceramide 1, or more recently called Ceramide EOP, was the first one that was identified in 1982 and it's a special snowflake. It contains the essential fatty acid, linoleic acid and has a unique structure. It's believed that ceramide 1 plays a "binding role" in the lipid layers of the extracellular matrix. Along with ceramides 4 and 7, they also play a vital role in epidermal integrity and serve as the main storage areas for linoleic acid (a fatty acid that's also very important for barrier repair).  

Oh, and one more thing: alkaline pH inhibits enzymes that help ceramide synthesis in our skin. So if you use a soap and you notice your skin is becoming dry, now you know why. 

Show me some proof

  • Meckfessel, Matthew H., and Staci Brandt. "The structure, function, and importance of ceramides in skin and their use as therapeutic agents in skin-care products." Journal of the American Academy of Dermatology 71.1 (2014): 177-184.
  • Leslie Baumann, MD, Cosmetic Dermatology, 2nd edition, Ceramides p85-86
  • Choi, Myeong Jun, and Howard I. Maibach. "Role of ceramides in barrier function of healthy and diseased skin." American journal of clinical dermatology 6.4 (2005): 215-223.
  • Huang, Huey‐Chun, and Tsong‐Min Chang. "Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate‐irritated skin." International journal of dermatology 47.8 (2008): 812-819.

Products with Ceramide EOP

CeraVe Makeup Removing Cleansing Cloths Eighteen B Hydrate + Restore Rich Cream Le Mieux Bio Cell Rejuvenating Cream Le Mieux Essence Moisturizer Meishoku Ceracolla Perfect Gel CeraVe Baby Healing Ointment TÖRLÉS CeraVe Hydrating Cleanser Cezanne Skin Conditioner High Moist Paula's Choice Hyaluronic Acid Booster Peter Thomas Roth Professional Strength 3% Retinoid Plus CeraVe Healing Ointment CeraVe Pm Facial Moisturizing Lotion Matsuyama Hadauru Moisturizing Infusion Moist Rich CeraVe Baby Moisturizing Lotion CeraVe Baby Wash & Shampoo Paula's Choice Calm Redness Relief Repairing Serum Peter Thomas Roth Water Drench Hyaluronic Cloud Cream Rodan and fields Soothe Gentle Cream Wash Skin Inc. Ceramide Serum CeraVe Daily Moisturizing Lotion Dr Dennis Gross Hyaluronic Marine Hydration Booster Elizabeth Arden Advanced Ceramide Capsules Daily Youth Restoring Serum Holika Holika Good Cera Super Ceramide Foaming Wash Kiku-masamune Sake Emulsion Paula's Choice Resist Omega+ Complex Serum Rosette Aqua Ceramide Gel l'amore beauty Intensive Eye Repair Serum CeraVe Baby Moisturizing Cream CeraVe Hydrating Hyaluronic Acid Serum CeraVe Moisturizing Cream Dr. Jart+ Ceramidin Liquid Elizabeth Arden Ceramide Youth Restoring Essence Kate Somerville Kx Active Concentrates Ceramides + Omegas Serum Rodan and fields Active Hydration Serum Apothaka Barrier Support Serum With Niacinamide & Ceramides Bioclarity Hydrate CeraVe Foaming Facial Cleanser CeraVe Renewing Sa Cleanser CeraVe Skin Renewing Vitamin C Serum Murad Nutrient-Charged Water Gel Rodan and fields Unblemish Dual Intensive Acne Treatment CeraVe Skin Renewing Gel Oil CeraVe Ultra-Light Moisturizing Face Lotion With Sunscreen Spf 30 Paula's Choice Resist Perfectly Balanced Foaming Cleanser CeraVe Am Facial Moisturizing Lotion Spf30 CeraVe Eczema Soothing Creamy Oil Elta MD Barrier Renewal Complex Medik8 Advanced Night Restore Paula's Choice Clinical Ultra-Rich Moisturizer CeraVe Repair Eye Cream