Melanonx Dark Spot Ampoule
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MEDIPEEL Melanonx Dark Spot AmpouleIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid).
Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier.
Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.
Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation.
If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.
As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily.
A water-soluble, colorless, odorless humectant liquid that makes your skin nice and smooth (aka emollient) and gives a dry, non-tacky skin feel. It also has great instant and some longer-lasting moisturizing effect and works in synergy with fellow moisturizer, sorbitol.
Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved.
It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
A nice odorless liquid used mainly as a superior solubilizer and efficacy booster for cosmetic active ingredients such as skincare bigshot vitamin C, self-tanning active DHA or the anti-acne gold standard, benzoyl peroxide.
Other than that it can also be used in hair care products where it gives a longer-lasting and more uniform coloring. According to a manufacturer, it might even prevent the formation of split ends.
- A multi-functional skincare superstar with several proven benefits for the skin
- Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
- Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
- Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
- Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
The emollient plant oil coming from the seeds of the white flowering plant called meadowfoam. Meadowfoam Oil has a unique fatty acid composition with 95% of it being long chain fatty acids (eicosenoic acid C20:1 - 61%, docosenoic acid C22:1 - 16% and docosadienoic acid C22:2 - 18%) that make the oil extraordinarily stable. It also contains antioxidant components such as vitamin E as well as phytosterols.
Apart from Meadowfoam Oil's crazy stability, the oil is described as non-greasy, rapidly absorbed and having a similar skin feel to more often used jojoba oil. The oil is ideal for products where a soft, smooth, silky feel is required whether it be on skin or hair.
A corn sugar derived, water-soluble, pale yellow syrup, that nicely moisturizes the skin. It has a light and smooth skin feel, it is non-tacky, and it can improve the after-feel of the formula. It is also mild and gentle, popular in sensitive skin formulas.
A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular.
We don't have description for this ingredient yet.
A clear, colorless liquid that works as a solvent and viscosity decreasing ingredient. It also has great skin-moisturizing abilities.
Unless you live under a rock you must have heard about shea butter. It's probably the most hyped up natural butter in skincare today. It comes from the seeds of African Shea or Karite Trees and used as a magic moisturizer and emollient.
But it's not only a simple emollient, it regenerates and soothes the skin, protects it from external factors (such as UV rays or wind) and is also rich in antioxidants (among others vitamin A, E, F, quercetin and epigallocatechin gallate). If you are looking for rich emollient benefits + more, shea is hard to beat.
A handy multifunctional ingredient that works as a preservative booster, as well as an antioxidant and soothing agent.
We don't have description for this ingredient yet.
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.
BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.
It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive.
It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol.
The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.
A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula. It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.
It's a little helper ingredient that helps to set the pH of the products to be right. It has an alkaline pH and can neutralize acidic ingredients.
A glycerin-derived gentle cleansing agent that is described as being skin and eye-friendly, and not leaving the skin dry or tight. It's also used as a co-emulsifier or solubilizer that helps to blend small amounts of oily things into water-based products.
It's the chemically chopped up version of normal lecithin. Most often it's used to create liposomes and to coat and stabilize other ingredients.
It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version.
According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E.
The extract coming from the root of the traditional medicinal herb, Coptis Japonica or Japanese Goldthread. The plant is used traditionally in East Asia for its anti-inflammatory, antioxidant and antimicrobial abilities.
Other than that, there is also an abstract from the International Journal of Cosmetic Science that found Coptis Japonica Root Extract and its active component called berberine to show potent inhibition of triglyceride (aka fat) accumulation and subcutaneous preadipocytes (the cells that become later fat cells) differentiation meaning that Goldthread Extract might also be useful in slimming and anti-cellulite products.
- Primary fat-soluble antioxidant in our skin
- Significant photoprotection against UVB rays
- Vit C + Vit E work in synergy and provide great photoprotection
- Has emollient properties
- Easy to formulate, stable and relatively inexpensive
An ester that comes from Cetearyl alcohol and the fatty acids of olive oil. It often comes to the formula coupled with Sorbitan Olivate as the two together form the well-known, natural emulsifier trade named Olivem 1000.
Other than helping oil and water to blend, the main thing of Olivem 1000 is generating liquid crystal structures that are similar to the lipid structures of the stratum corneum (the outermost layer of the skin). Thanks to this, Olivem 1000 doubles as an active ingredient with significant moisturizing, barrier-repairing and soothing properties.
It also helps to deliver water-soluble actives such as caffeine more effectively, and can even boost SPF in sunscreen formulas. Its typical use level is 1-5% and has wide compatibility with other actives and oils.
Overall, a real multi-tasker with nice sensorial properties. No wonder it is so popular.
Though its long name does not reveal it, this polymer molecule (big molecule from repeated subunits or monomers) is a relative to the super common, water-loving thickener, Carbomer. Both of them are big molecules that contain acrylic acid units, but Acrylates/C10-30 Alkyl Acrylate Crosspolymer also contains some other monomers that are hydrophobic, i.e. water-hating.
This means that our molecule is part water- and part oil-loving, so it not only works as a thickener but also as an emulsion stabilizer. It is very common in gel-type formulas that also contain an oil-phase as well as in cleansers as it also works with most cleansing agents (unlike a lot of other thickeners).
A kind of polymer (big molecule from repeated subunits) that helps to create beautiful gel-like textures. It's also a texturizer and thickener for oil-in-water emulsions. It gives products a good skin feel and does not make the formula tacky or sticky.
It works over a wide pH range and is used between 0.5-1.2%.
A big polymer (created from repeating subunits) molecule that works as a film former and hair fixative agent.
It is a modified version of the first and classic hair fixative, PVP that alternates the water-loving VP (Vinyl Pyrrolidone) units with water-hating VA (Vinyl Acetate) units to create a film that is less brittle and less sensitive to air humidity.
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
It is typically used in tiny amounts, around 0.1% or less.
A common little helper ingredient that helps water and oil to mix together, aka emulsifier.
An ester coming from sorbitol and the fatty acids of olive oil. It is part of the popular emulsifier trade named Olivem 1000 that is well-known for generating biomimetic liquid crystal structures. We have more info on Olivem 1000 at Cetearyl Olivate >>
Adenosine is an important little compound in our body that has a vital cell-signalling role. Research on smearing it on our face is also promising and shows so far a couple of things:
- It can help with wound healing
- It’s a good anti-inflammatory agent
- It might even help with skin’s own collagen production and improve skin firmness and elasticity
- It helps with barrier repair and protection
- It might be even useful for the hair helping with hair thickness and hair growth
Sunflower does not need a big intro as you probably use it in the kitchen as cooking oil, or you munch on the seeds as a healthy snack or you adore its big, beautiful yellow flower during the summer - or you do all of these and probably even more. And by even more we mean putting it all over your face as sunflower oil is one of the most commonly used plant oils in skincare.
It’s a real oldie: expressed directly from the seeds, the oil is used not for hundreds but thousands of years. According to The National Sunflower Association, there is evidence that both the plant and its oil were used by American Indians in the area of Arizona and New Mexico about 3000 BC. Do the math: it's more than 5000 years – definitely an oldie.
Our intro did get pretty big after all (sorry for that), so let's get to the point finally: sunflower oil - similar to other plant oils - is a great emollient that makes the skin smooth and nice and helps to keep it hydrated. It also protects the surface of the skin and enhances the damaged or irritated skin barrier. Leslie Bauman notes in Cosmetic Dermatology that one application of sunflower oil significantly speeds up the recovery of the skin barrier within an hour and sustains the results 5 hours after using it.
It's also loaded with fatty acids (mostly linoleic (50-74%) and oleic (14-35%)). The unrefined version (be sure to use that on your skin!) is especially high in linoleic acid that is great even for acne-prone skin. Its comedogen index is 0, meaning that it's pretty much an all skin-type oil.
Truth be told, there are many great plant oils and sunflower oil is definitely one of them.
Baobab is a really big, iconic tree native to Africa (here is a nice image of it). It's the largest succulent plant in the world and almost all parts of it have traditional medicinal uses in Africa.
The seed oil, similar to other plant oils, is loaded with things that are good-for-the-skin: it contains skin regenerating vitamin A, antioxidant vitamin E, and vitamin D3 that helps with calcium absorption. It's rich in nourishing fatty acids oleic (30-40%), linoleic (24-34%) and palmitic (18-30%).
Its moisturizing benefits are impressive, it absorbed into the skin quickly and might even improve skin elasticity. A great oil for drier skin types and excellent for eczema and psoriasis.
A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives.
A clear, colorless, low viscosity, volatile (does not absorb into the skin but rather evaporates from it) silicone fluid that has excellent spreadability and leaves a light, silky and smooth feel on the skin.
According to manufacturer info, its big advantage is that it's compatible both with other silicones and with natural plant oils, so it's a great ingredient to formulate products with good-sounding, consumer-pleasing vegetable oils but still maintain a cosmetically elegant, non-greasy and non-tacky feel.
Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.
As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity.
As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types).
A hydrocarbon-based emollient that can come in different viscosities from silky-light through satiny-smooth to luxurious, rich. It forms a non-occlusive film on the surface of the skin and brings gloss without greasiness to the formula. It's a very pure and hypoallergenic emollient that's also ideal for baby care products.
Triethylhexanoin is a colorless to pale yellow liquid ester that makes the skin nice and smooth, aka emollient. It has a pleasant non-sticky, non-greasy feel to it, gives formulas smooth application properties and also helps moisture retention.
One of the many types of ceramides that can be found naturally in the upper layer of the skin. Ceramides make up about 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated. It works even better when combined with its pal, Ceramide 1.
We wrote way more about ceramides at ceramide 1, so click here to know more.
A white, waxy emollient that gives "body" to skincare formulas. Comes from coconut or palm kernel oil.
A creamy solid that helps water and oil to mix, aka emulsifier. Its solid, wax-like nature is useful for oil-based formulas where some rigidity is needed.
We don't have description for this ingredient yet.
It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.
As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution".
In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).
What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists.
If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
If you are reading here, we are pretty sure the words retinoids and retinol ring a bell, but if not, you are seriously missing out, please click here immediately to catch up. The TL;DR version is that retinoids are the royal family of skincare with tretinoin being the king, the only FDA-approved ingredient to treat the signs of photoaging. Retinol is like a grandkid, it has to be converted (through two steps) in the skin to become retinoic acid. The conversion means retinol is both less effective and less harsh on the skin.
So where does our current molecule, Retinal, aka Retinaldehyde fit into the family (btw, here is a nice visual family tree about who is who)? Remember that retinol needed two conversion steps to become retinoic acid? Yes, you are right, Retinal is the intermediate step between retinoic acid and retinol, meaning it needs only one conversion step to become active in the skin. If we go with our royal family analogy, Retinal is Prince William, directly next in line to the throne.
Once retinal is converted, it becomes retinoic acid and does the same things we detailed in our tretinoin description. In a nutshell, it is everything you expect from an anti-aging superstar such as decreased wrinkles, smoother, firmer and more elastic skin.
This sounds good, but how does Retinal compare to retinoic acid? Good question! We found a study (a pretty good one with 125 patients) that compared 0.05% retinal with 0.05% retinoic acid (and vehicle). They concluded that "at week 18, a significant reduction of the wrinkle and roughness features was observed with both retinaldehyde and retinoic acid." and the difference between the two was not statistically significant. (Interestingly, in both groups, the results were less significant at week 44, so it might be a good idea to have a retinoid break from time to time?) Also, our guy, Retinal was much better tolerated than retinoic acid known for its harshness.
The good tolerability of retinal was also confirmed by another study that compared retinol (ROL), retinal (RAL) and retinoic acid (RA). They found that "the natural retinoids ROL and RAL do have a good tolerance profile, in contrast with the irritating potential of RA", meaning retinal is an awesome alternative if you have irritation and flaking issues with prescription products, such as Retin-A.
Last, but not least, we want to mention a pretty big (but subjectively evaluated), Avene (the French pharmacy brand famous for its Retinal products) sponsored study that examined the tolerability and efficacy of a 0.1 Retinal + 6% glycolic acid product in the treatment of acne. The product was added next to the standard anti-acne regimen of 1,709 patients for 90 days and the study concluded that the formula was both very well tolerated as well as effective next to other standard anti-acne medications such as benzoyl peroxide and antibiotics.
Overall, if you are into retinoids, Retinal is a really awesome and well-proven member of the family that is absolutely worth trying.
The salt form of one of the main anti-inflammatory ingredients in the licorice plant, monoammonium glycyrrhizinate. It’s a yellowish powder with a nice sweet smell.
It’s used mainly for its soothing and anti-inflammatory properties, but according to manufacturer info, it’s also sebum regulating so it's a perfect ingredient for problem skin products.
Read more about licorice and why it's a skincare superstar here.
We don't have description for this ingredient yet.
It's a special "cross-linked" from of IT-moisturizer, hyaluronic acid (HA). Cross-linked means that "normal" HA pieces (1-2 million Da molecular weight) are chemically bound togeather to create a big, "infinite" mesh.
The special HA mesh has a remarkable water-binding capacity, 5 times more than the already crazy water-binding capacity of "normal" HA. This water filled crosslinked HA gel forms a smooth film on the skin and continuously delivers the bound water, so it gives long-term moisturizing benefits.
Btw, crosslinking HA was developed for dermal fillers (as crosslinking helps their longevity), and this guy is the topical version of FDA approved dermal filler called Hylan B gel. Smearing crosslinked version all over ourselves is a newish thing, and incoming evidence so far suggests that it's a great idea, even better than normal HA.
A very recent, 2016 research article compared the topical moisturizing effect of crosslinked HA (not Hylan B gel specifically, but something called Resilient HA or RHA), HMW-HA and LMW-HA and found that "TEWL (that is trans-epidermal water loss, the water that evaporates from the skin) was reduced by 27.8% with RHA, and by 15.6% with HMW HA, but increased by 55.5% with LMW HA." (You can read much more about HMW and LMW HA here in the geeky details section.)
All in all, we think Sodium Hyaluronate Crosspolymer is an awesome version of HA, probably superior to traditional versions, so be happy to spot it on the ingredient list.
It's an ester form of vitamin A (retinol + palmitic acid) that belongs to the "retinoid family". The retinoid family is pretty much the royal family of skincare, with the king being the FDA-approved anti-aging ingredient tretinoin. Retinol is also a very famous member of the family, but it's like Prince George, two steps away from the throne. Retinyl palmitate will be then Prince Charlotte (George's little sister), quite far (3 steps) away from the throne.
By steps, we mean metabolic steps. Tretinoin, aka retinoic acid, is the active ingredient our skin cells can understand and retinyl palmitate (RP) has to be converted by our metabolic machinery to actually do something. The conversion is a 3 step one and looks like this:
retinyl palmitate --> retinol -- > retinaldehyde --> all-trans-retinoic acid
As we wrote in our lengthy retinol description the problem is that the conversion is not terribly effective. The evidence that RP is still an effective anti-aging ingredient is not very strong, in fact, it's weak. Dr. Leslie Baumann in her fantastic Cosmetic Dermatology book writes that RP is topically ineffective.
What's more, the anti-aging effectiveness is not the only questionable thing about RP. It also exibits questionable behaviour in the presence of UV light and was the center of a debate between the non-profit group, EWG (whose intentions are no doubt good, but its credibility is often questioned by scientists) and a group of scientists and dermatologists lead by Steven Q. Wang, MD, director of dermatologic surgery at Memorial-Sloan Kettering Cancer Centre.
Dr. Leslie Baumann wrote a great review of the debate and summarized the research available about retinyl palmitate here. It seems that there is a study showing RP being photo protective against UVB rays but there is also a study showing RP causing DNA damage and cytotoxicity in association with UVA.
We think that the truth lies somewhere in the middle, and we agree with Dr. Baumann's conclusion: "sufficient evidence to establish a causal link between RP and skin cancer has not been produced. Nor, I’m afraid, are there any good reasons to recommend the use of RP". We would add especially during the day!
Bottom line: If you wanna get serious about retinoids, RP is not your ingredient (retinol or tretinoin is!). However, if you use a product that you like and it also contains RP, there is no reason to throw it away. If possible use it at night, just to be on the safe side.
Hydrolyzed Hyaluronic Acid is a low molecular weight, chemically chopped up version of the naturally big molecule and current IT-moisturizer, Hyaluronic Acid (HA). The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to retain water, making it plump and elastic. As HA is a polymer, the subunits can be repeated many times (as a high-molecular-weight version), or just a few times (as a low-molecular-weight version).
We wrote in detail at HA about how different molecular weight versions do different things both as a component of the skin and as a skincare ingredient, so click here and read about all the details. Hydrolyzed Hyaluronic Acid can also come in different molecular-weight versions with different properties:
- 100-300 kDa version: apart from moisturizing, this size might also help the skin to repair itself by increasing its self-defense. It is also claimed to boost the wound healing process and is especially helpful for sensitive skin types (acne, rosacea, inflammation-related skin diseases).
- 50k Da version: this is the size that is claimed to be able to absorb into the skin and plump up wrinkles, so it is used mainly as an "anti-aging ingredient"
- below 50k, around 10k Da version: there is a Japanese version trade named Hyalo-Oligo that has only a 10k molecular weight and is claimed to penetrate the skin very well, have a unique touch and give deep and long-lasting moisturization. Based on the Evonik-research and the natural role of LMW-HA in the body working as a pro-inflammatory signal molecule, this ultra-low molecular weight version is a controversial ingredient.
If you wanna become a real HA-and-the-skin expert, you can read much more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.
Also, it's an effective deodorant and a medium spreading emollient.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
A type of ceramide that can be found naturally in the upper layer of the skin. Ceramides make up 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated.
We have written way more about ceramides at ceramide 1, so click here to know more.
Ceramides get quite a lot of hype recently and good news: there is a reason for that. But before we go into the details, let's just quickly define what the heck ceramides are:
They are waxy lipids that can be found naturally in the outer layer of the skin (called stratum corneum - SC). And they are there in big amounts! The goopy stuff between our skin cells is called extracellular matrix that consists mainly of lipids. And ceramides are about 50% of those lipids (the other important ones are cholesterol with 25% and fatty acids with 15%).
Ok, so now we know what ceramides are, let's see what they do in our skin: research shows clearly that they play a super important role in keeping the skin barrier healthy and the skin hydrated. If ceramides in the skin are decreased, more water can evaporate from the skin and there is less water remaining in the skin. So ceramides form kind of a "water-proof" protecting layer and make sure that our skin remains nice and hydrated.
Now the question is only this: If we put ceramides all over our face do they work as well as ceramides already naturally in our skin? Well, the answer is probably a no, but they do work to some extent. The BeautyBrains blog made a fantastic article about ceramides and they have listed a couple of examples about studies showing that ceramides - especially when used in certain ratios with cholesterol and fatty acids - do hydrate the skin and can help to repair the skin barrier.
So far we were writing about ceramides in plural. It's because there are lots of different ceramides, a 2014 article writes that currently 12 base classes of ceramides are known with over 340 specific species. Chemically speaking, ceramides are the connection of a fatty acid and a sphingoid base and both parts can have different variations that result in the different types of ceramides.
Our current one, Ceramide 1, or more recently called Ceramide EOP, was the first one that was identified in 1982 and it's a special snowflake. It contains the essential fatty acid, linoleic acid and has a unique structure. It's believed that ceramide 1 plays a "binding role" in the lipid layers of the extracellular matrix. Along with ceramides 4 and 7, they also play a vital role in epidermal integrity and serve as the main storage areas for linoleic acid (a fatty acid that's also very important for barrier repair).
Oh, and one more thing: alkaline pH inhibits enzymes that help ceramide synthesis in our skin. So if you use a soap and you notice your skin is becoming dry, now you know why.
We don't have description for this ingredient yet.
- Works best between a concentration of 5-20%
- Boosts the skin’s own collagen production
- Fades pigmentation and brown spots
- If used under sunscreen it boosts its UV protection
- Extremely unstable and oxidizes very easily in presence of light or air
- Stable in solutions with water only if pH is less than 3.5 or in waterless formulations
- Vit E + C work in synergy and provide superb photoprotection
- Ferulic acid doubles the photoprotection effect of Vit C+E and helps to stabilize Vit C
- Potent Vit. C serums might cause a slight tingling on sensitive skin
We don't have description for this ingredient yet.
- It’s naturally in our skin and behaves there like a sponge
- It can bind up to 1000 times its own weight in water
- It is a big molecule from repeated subunits (polymer) so different molecular weight versions exist (unfortunately there is no way to determine MW from INCI list only)
- High-molecular-weight-HA (>500 kDa) is an excellent surface hydrator, skin protectant and can act as an osmotic pump helping water-soluble actives to penetrate deeper into the skin
- Low-molecular-weight-HA (< 500 kDa) can hydrate the skin somewhat deeper though it is still a big molecule and works mainly in the epidermis (outer layer of the skin)
- Low-molecular-weight-HA might also help the skin to repair itself by increasing its self-defense (~ 200kDa used in the study)
- Ultra-low-molecular-weight-HA (<50kDa) is a controversial ingredient and might work as a pro-inflammatory signal molecule
Sodium Acetylated Hyaluronate is a variation of current IT moisturizer, Hyaluronic acid, where some water-loving -OH groups are replaced by amphipathic (partly water-loving and partly water-hating) acetyl groups. The modified molecule is claimed to have even better moisture retention ability than normal HA and better affinity to the skin surface.
The better affinity comes from the acetyl groups that act as tiny "anchors" to attach the HA molecule to the skin. Staying on top of the skin better and longer means longer-lasting surface hydration and improved elasticity. It is also less sticky and more cosmetically elegant than normal HA, so no wonder the nickname of this molecule is super hyaluronic acid.
Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!).
If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.
Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!).
A super common and cheap fragrance ingredient. It's in many plants, e.g. rosemary, eucalyptus, lavender, lemongrass, peppermint and it's the main component (about 50-90%) of the peel oil of citrus fruits.
It does smell nice but the problem is that it oxidizes on air exposure and the resulting stuff is not good for the skin. Oxidized limonene can cause allergic contact dermatitis and counts as a frequent skin sensitizer.
Limonene's nr1 function is definitely being a fragrance component, but there are several studies showing that it's also a penetration enhancer, mainly for oil-loving components.
All in all, limonene has some pros and cons, but - especially if your skin is sensitive - the cons probably outweigh the pros.
A common fragrance ingredient that smells like jasmine. It is one of the “EU 26 fragrances” that has to be labelled separately because of allergen potential. Best to avoid if your skin is sensitive.
It’s a common fragrance ingredient that has a light floral smell. It’s one of the “EU 26 fragrances” that has to be labelled separately (and cannot be simply included in the term “fragrance/perfume” on the label) because of allergen potential. Best to avoid if your skin is sensitive.
Linalool is a super common fragrance ingredient. It’s kind of everywhere - both in plants and in cosmetic products. It’s part of 200 natural oils including lavender, ylang-ylang, bergamot, jasmine, geranium and it can be found in 90-95% of prestige perfumes on the market.
The problem with linalool is, that just like limonene it oxidises on air exposure and becomes allergenic. That’s why a product containing linalool that has been opened for several months is more likely to be allergenic than a fresh one.
A study made in the UK with 483 people tested the allergic reaction to 3% oxidised linalool and 2.3% had positive test results.
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| what‑it‑does | solvent |
| what‑it‑does | soothing | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | solvent | moisturizer/humectant | emollient |
| what‑it‑does | solvent | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | solvent | moisturizer/humectant | perfuming |
| irritancy, com. | 0, 0 |
| what‑it‑does | cell-communicating ingredient | skin brightening | anti-acne | moisturizer/humectant |
| what‑it‑does | emollient |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | emollient |
| what‑it‑does | solvent |
| what‑it‑does | emollient |
| what‑it‑does | antioxidant | preservative |
| what‑it‑does | skin brightening | soothing |
| what‑it‑does | viscosity controlling |
| what‑it‑does | moisturizer/humectant | solvent |
| irritancy, com. | 0, 1 |
| what‑it‑does | moisturizer/humectant | emollient |
| what‑it‑does | viscosity controlling |
| irritancy, com. | 0, 1 |
| what‑it‑does | buffering |
| what‑it‑does | surfactant/cleansing | emulsifying |
| what‑it‑does | emollient | emulsifying |
| what‑it‑does | antioxidant |
| irritancy, com. | 0, 0 |
| what‑it‑does | soothing | antioxidant |
| what‑it‑does | antioxidant |
| irritancy, com. | 0-3, 0-3 |
| what‑it‑does | emulsifying |
| what‑it‑does | viscosity controlling |
| what‑it‑does | viscosity controlling |
| what‑it‑does | chelating |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | emulsifying |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | emollient |
| irritancy, com. | 0, 0 |
| what‑it‑does | emollient |
| what‑it‑does | solvent |
| what‑it‑does | emollient |
| what‑it‑does | emollient |
| irritancy, com. | 0, 1 |
| what‑it‑does | emollient | perfuming | solvent |
| what‑it‑does | emollient | perfuming |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | solvent |
| what‑it‑does | emollient |
| irritancy, com. | 0, 0 |
| what‑it‑does | emulsifying |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | soothing | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | antioxidant | moisturizer/humectant |
| what‑it‑does | cell-communicating ingredient |
| irritancy, com. | 1-3, 1-3 |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | preservative |
| irritancy, com. | 0, 2 |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | antioxidant | skin brightening | buffering |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | perfuming |
| what‑it‑does | perfuming | solvent |
| what‑it‑does | perfuming |
| what‑it‑does | perfuming |
| what‑it‑does | perfuming |