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BioHeal BOH Panthecell Repair Cicasome Cream

Panthecell Repair Cicasome Cream

Helps with improving skin thickness along with soothing effect.
Uploaded by: moorem23 on

Ingredients overview

Water, Panthenol, Butylene Glycol, Glycerin, Behenyl Alcohol, Butylene Glycol Dicaprylate/​Dicaprate, Propanediol, Arachidyl Alcohol, 1,2-Hexanediol, Cetyl Ethylhexanoate, Pentaerythrityl Tetraethylhexanoate, Squalane, Dicaprylyl Carbonate, Pentylene Glycol, Candida Bombicola/​Glucose/​Methyl Rapeseedate Ferment, Helianthus Annuus (Sunflower) Seed Oil, Centella Asiatica Leaf Vesicles, Macadamia Ternifolia Seed Oil, Sodium Hyaluronate, Centella Asiatica Leaf Extract, Vinyl Dimethicone, Arachidyl Glucoside, Glyceryl Stearate, Polyacrylate Crosspolymer-6, Aminomethyl Propanediol, Polyacrylate-13, C12-20 Alkyl Glucoside, Ceramide NP, Ethylhexylglycerin, Hydrogenated Polyisobutene, Sodium Phytate, Dipropylene Glycol, Polyglyceryl-10 Laurate, Ammonium Acryloyldimethyltaurate/​VP Copolymer, Ethylhexyl Palmitate, Sorbitan Isostearate, Beta-Sitosterol, Sodium Chloride, Tocopherol, Phytosterols, Trehalose, Octyldodecanol, Phosphatidylcholine, Asiaticoside, Asiatic Acid, Glycolipids, Hydrogenated Lecithin, Madecassic Acid, Disodium Phosphate, Caprylyl Glycol, Sodium Hyaluronate Crosspolymer, Potassium Phosphate, Tripeptide-10 Citrulline, Potassium Chloride, Sorbitol, Citric Acid, Acetyl Hexapeptide-8, Ascorbic Acid Polypeptide, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Acetyl Tetrapeptide-3, Acetyl Tetrapeptide-5, Acetyl Tetrapeptide-9, Carnosine, Copper Tripeptide-1, Nonapeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, C14-22 Alcohols, Carbomer, Cetearyl Alcohol

Highlights

#alcohol-free #fragrance & essentialoil-free
Alcohol Free
Fragrance and Essential Oil Free

Skim through

Ingredient name what-it-does irr., com. ID-Rating
Water solvent
Panthenol soothing, moisturizer/​humectant 0, 0 goodie
Butylene Glycol moisturizer/​humectant, solvent 0, 1
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Behenyl Alcohol emollient, viscosity controlling
Butylene Glycol Dicaprylate/Dicaprate emollient
Propanediol solvent, moisturizer/​humectant
Arachidyl Alcohol emollient, viscosity controlling
1,2-Hexanediol solvent
Cetyl Ethylhexanoate emollient
Pentaerythrityl Tetraethylhexanoate emollient, viscosity controlling
Squalane skin-identical ingredient, emollient 0, 1 goodie
Dicaprylyl Carbonate emollient
Pentylene Glycol solvent, moisturizer/​humectant
Candida Bombicola/Glucose/Methyl Rapeseedate Ferment antimicrobial/​antibacterial, surfactant/​cleansing
Helianthus Annuus (Sunflower) Seed Oil emollient 0, 0 goodie
Centella Asiatica Leaf Vesicles
Macadamia Ternifolia Seed Oil emollient goodie
Sodium Hyaluronate skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Centella Asiatica Leaf Extract soothing, antioxidant, moisturizer/​humectant goodie
Vinyl Dimethicone viscosity controlling
Arachidyl Glucoside emulsifying, surfactant/​cleansing
Glyceryl Stearate emollient, emulsifying 0, 1
Polyacrylate Crosspolymer-6 viscosity controlling
Aminomethyl Propanediol buffering
Polyacrylate-13
C12-20 Alkyl Glucoside emulsifying, surfactant/​cleansing
Ceramide NP skin-identical ingredient goodie
Ethylhexylglycerin preservative
Hydrogenated Polyisobutene emollient, viscosity controlling 2, 1
Sodium Phytate chelating
Dipropylene Glycol solvent
Polyglyceryl-10 Laurate surfactant/​cleansing, emulsifying
Ammonium Acryloyldimethyltaurate/VP Copolymer viscosity controlling
Ethylhexyl Palmitate emollient 0, 2-4
Sorbitan Isostearate emulsifying 0, 1-2
Beta-Sitosterol
Sodium Chloride viscosity controlling
Tocopherol antioxidant 0-3, 0-3 goodie
Phytosterols
Trehalose moisturizer/​humectant goodie
Octyldodecanol emollient, perfuming
Phosphatidylcholine emulsifying
Asiaticoside antioxidant, perfuming goodie
Asiatic Acid goodie
Glycolipids
Hydrogenated Lecithin emollient, emulsifying goodie
Madecassic Acid goodie
Disodium Phosphate buffering
Caprylyl Glycol moisturizer/​humectant, emollient
Sodium Hyaluronate Crosspolymer skin-identical ingredient, antioxidant, moisturizer/​humectant goodie
Potassium Phosphate buffering
Tripeptide-10 Citrulline
Potassium Chloride viscosity controlling
Sorbitol moisturizer/​humectant 0, 0
Citric Acid buffering
Acetyl Hexapeptide-8 cell-communicating ingredient, moisturizer/​humectant goodie
Ascorbic Acid Polypeptide antioxidant
Acetyl Octapeptide-3 cell-communicating ingredient, moisturizer/​humectant goodie
Acetyl Tetrapeptide-2 cell-communicating ingredient goodie
Acetyl Tetrapeptide-3 cell-communicating ingredient goodie
Acetyl Tetrapeptide-5 cell-communicating ingredient, moisturizer/​humectant goodie
Acetyl Tetrapeptide-9
Carnosine antioxidant, cell-communicating ingredient goodie
Copper Tripeptide-1 cell-communicating ingredient, soothing, antioxidant goodie
Nonapeptide-1
Palmitoyl Pentapeptide-4 cell-communicating ingredient goodie
Palmitoyl Tripeptide-1 cell-communicating ingredient goodie
Palmitoyl Tripeptide-5 cell-communicating ingredient goodie
C14-22 Alcohols
Carbomer viscosity controlling 0, 1
Cetearyl Alcohol emollient, viscosity controlling, emulsifying, surfactant/​cleansing 1, 2

BioHeal BOH Panthecell Repair Cicasome Cream
Ingredients explained

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

Panthenol - goodie
Also-called: Pro-Vitamin B5 | What-it-does: soothing, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid). 

Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier. 

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

A fatty alcohol (the non-drying type with a long oil loving chain of 22 carbon atoms) that is used to increase the viscosity of the formula and it also helps the oily and the watery parts to stay nicely mixed together (called emulsion stabilizing). 

What-it-does: emollient

We don't have description for this ingredient yet.

Also-called: Zemea | What-it-does: solvent, moisturizer/humectant

Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved. 

It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. 

A fatty alcohol (the non-drying type with a long oil loving chain of 20 carbon atoms) that is used to increase the viscosity of the formula and it also helps the oily and the watery parts to stay nicely mixed together (called emulsion stabilizing). 

What-it-does: solvent

A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives

What-it-does: emollient

An odorless and colorless emollient ester (cetyl alcohol + ethylhexanoic acid) that gives a velvety and silky feel to the skin. It has great spreadability and a non-oily feel. It's a popular ingredient in makeup removers.

A high-molecular-weight emollient ester that makes your skin nice and smooth. It leaves a non-oily, light, "wet" feel on the skin. 

Squalane - goodie
What-it-does: skin-identical ingredient, emollient | Irritancy: 0 | Comedogenicity: 1

It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated  (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life. 

It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy.

What-it-does: emollient

A clear, colorless, almost odorless oil that spreads nicely and easily and gives a velvet dry skin feel. It is good friends with sunscreen agents and helps to solubilize them. Also, it makes sunscreens feel lighter and spread easier. 

A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent and a broad spectrum antimicrobial. According to manufacturer info, it's also a moisturizer and helps to make the product feel great on the skin. It works synergistically with preservatives and helps to improve water-resistance of sunscreens. 

Also-called: Sunflower Oil | What-it-does: emollient | Irritancy: 0 | Comedogenicity: 0

Sunflower does not need a big intro as you probably use it in the kitchen as cooking oil, or you munch on the seeds as a healthy snack or you adore its big, beautiful yellow flower during the summer - or you do all of these and probably even more. And by even more  we mean putting it all over your face as sunflower oil is one of the most commonly used plant oils in skincare.

It’s a real oldie: expressed directly from the seeds, the oil is used not for hundreds but thousands of years. According to The National Sunflower Association, there is evidence that both the plant and its oil were used by American Indians in the area of Arizona and New Mexico about 3000 BC. Do the math: it's more than 5000 years – definitely an oldie.

We don't have description for this ingredient yet.

Also-called: Macadamia Oil | What-it-does: emollient

The golden yellow oil coming from the Macadamia nut, a native Australian nut. Similar to other plant oils, it's loaded with emollient and nourishing fatty acids. It's a high oleic acid oil (50-67% oleic acid and only 0-5% linoleic acid) that makes it very emollient and ideal for dry skin types (and less ideal for acne-prone skin).

Its unique property is that it contains high amounts of a rare fatty acid called palmitoleic acid (12-25%) that give Macadamia oil a "cushiony" feel. It's also easily absorbed and makes the skin soft and supple. 

What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It’s the - sodium form - cousin of the famous NMFhyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

We don't have description for this ingredient yet.

What-it-does: viscosity controlling

We don't have description for this ingredient yet.

An ingredient that is created from the attachment of the water-loving sugar molecule, glucose, and an oil-loving 20 carbon long fatty chain. This makes it a partly water- and partly oil-soluble material, meaning it functions as an emulsifier helping oil and water to mix.  

Most often, it comes to the formula coupled with two fatty alcohol friends, Arachidyl and Behenyl alcohol, to make up an emulsifier trio trade named Montanov 202. As described by its manufacturer, the main thing of Montanonv 202 is that it gives creams a unique evanescent and light feel with a matt finish. It also leaves the skin soft, but not oily, is hypoallergenic and non-comedogenic making it perfect for both oily and sensitive skin formulas. 

What-it-does: emollient, emulsifying | Irritancy: 0 | Comedogenicity: 1

A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.

Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.

It's a helper ingredient that helps to thicken up formulas and form a nice gel texture. It leaves a rich, elegant feel with a velvety finish on the skin and works over a wide pH range.

What-it-does: buffering

We don't have description for this ingredient yet.

A helper ingredient that functions as a film-forming polymer (big molecule from repeated subunits).

It usually comes to the formula as part of a thickener-emulsifier trio paired with Polyisobutene and Polysorbate 20. The three togeather have excellent thickening properties with remarkable emulsifying-stabilising abilities. They also have a nice silicone feel with glide-on spreading. 

A 100% vegetable origin emulsifier that usually comes to the formula with its buddy called C14-22 Alcohols. The duo is called Montanov L and two together help to create ultra-soft light formulas.

Ceramide NP - goodie
Also-called: Ceramide 3 | What-it-does: skin-identical ingredient

One of the many types of ceramides that can be found naturally in the upper layer of the skin. Ceramides make up about 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated. It works even better when combined with its pal, Ceramide 1.

We wrote way more about ceramides at ceramide 1, so click here to know more.

What-it-does: preservative, deodorant

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient

What-it-does: emollient, viscosity controlling | Irritancy: 2 | Comedogenicity: 1

A synthetic liquid oil that can replace mineral oil or silicone oils in the cosmetic formulas. There are different grades depending on the molecular weight ranging from very light, volatile, non-residue leaving ones to more substantial, slight residue leaving ones.

Apart from leaving the skin soft and smooth (emollient), it's also used as a waterproofing agent in sunscreens or makeup products and as a shine enhancer in lip gloss formulas. 

What-it-does: chelating

It’s one of those little helper ingredients that makes sure the product stays the same over time. No color change or anything like that. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. 

What-it-does: solvent

A clear, colorless liquid that works as a solvent and viscosity decreasing ingredient. It also has great skin-moisturizing abilities. 

A glycerin-derived gentle cleansing agent that is described as being skin and eye-friendly, and not leaving the skin dry or tight. It's also used as a co-emulsifier or solubilizer that helps to blend small amounts of oily things into water-based products. 

Also-called: Aristoflex AVC | What-it-does: viscosity controlling

A kind of polymer (big molecule from repeated subunits) that helps to create beautiful gel-like textures. It's also a texturizer and thickener for oil-in-water emulsions. It gives products a good skin feel and does not make the formula tacky or sticky. 

It works over a wide pH range and is used between 0.5-1.2%.

What-it-does: emollient | Irritancy: 0 | Comedogenicity: 2-4

A super common, medium-spreading emollient ester that gives richness to the formula and a mild feel during rubout. It can be a replacement for mineral oil and is often combined with other emollients to achieve different sensorial properties.

What-it-does: emulsifying | Irritancy: 0 | Comedogenicity: 1-2

A handy helper ingredient that helps water and oil to mix nicely together, aka emulsifier. It is especially recommended for protective, baby care and general purpose emollient creams. 

It also helps to disperse insoluble particles (think color pigments or zinc/titanium dioxide sunscreen) nice and even in cosmetic formulas. 

What-it-does: emulsion stabilising

We don't have description for this ingredient yet.

Also-called: Salt | What-it-does: viscosity controlling

Sodium chloride is the fancy name of salt. Normal, everyday table salt

If (similar to us) you are in the weird habit of reading the label on your shower gel while taking a shower, you might have noticed that sodium chloride is almost always on the ingredient list. The reason for this is that salt acts as a fantastic thickener in cleansing formulas created with ionic cleansing agents (aka surfactants) such as Sodium Laureth Sulfate. A couple of percents (typically 1-3%) turns a runny surfactant solution into a nice gel texture.

Tocopherol - goodie
Also-called: Vitamin E | What-it-does: antioxidant | Irritancy: 0-3 | Comedogenicity: 0-3
  • Primary fat-soluble antioxidant in our skin
  • Significant photoprotection against UVB rays
  • Vit C + Vit E work in synergy and provide great photoprotection
  • Has emollient properties
  • Easy to formulate, stable and relatively inexpensive
Read all the geeky details about Tocopherol here >>

We don't have description for this ingredient yet.

Trehalose - goodie
What-it-does: moisturizer/humectant

A type of sugar that has water-binding properties and helps to keep your skin hydrated

What-it-does: emollient, perfuming

A clear, slightly yellow, odorless oil  that's a very common, medium-spreading emollient. It makes the skin feel nice and smooth and works in a wide range of formulas.

What-it-does: emulsifying

We don't have description for this ingredient yet.

Asiaticoside - goodie
What-it-does: antioxidant, perfuming

One of the main biologically active components of the famous medicinal plant, Centella Asiatica, aka Gotu Kola. It has well established wound healing and antioxidant activities.  

In-vitro (made in the lab) studies also show that Asiaticoside stimulates GAGs (glycosaminoglycans - polysaccharides that are part of the liquidy stuff between our skin cells) production as well as collagen I synthesis.  Read more at Gotu Kola >>

Asiatic Acid - goodie

One of the biologically active components of Gotu Kola. It's a bit less prominent than its sister component, Asiaticoside, but in-vitro (made in the lab) studies show that Asiatic Acid also stimulates GAGs (glycosaminoglycans - polysaccharides that are part of the liquidy stuff between our skin cells) production as well as collagen I synthesis.

English translation equals that it probably contributes to the well-established moisturizing and wound healing abilities of Gotu Kola

We don't have description for this ingredient yet.

What-it-does: emollient, emulsifying

It's the chemically chopped up version of normal lecithin. Most often it's used to create liposomes and to coat and stabilize other ingredients. 

One of the biologically active components of Gotu Kola that is thought to contribute to the plant extract's well-documented skin regenerating, wound healing, and moisturizing properties

If you are into Gotu Kola we have some more info at Centella Asiatica Extract and its other biologically active components MadecassosideAsiaticoside and Asiatic Acid.

What-it-does: buffering

We don't have description for this ingredient yet.

It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol

The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.

It's a special "cross-linked" from of IT-moisturizer, hyaluronic acid (HA). Cross-linked means that "normal" HA pieces (1-2 million Da molecular weight) are chemically bound togeather to create a big, "infinite" mesh.

The special HA mesh has a remarkable water-binding capacity, 5 times more than the already crazy water-binding capacity of "normal" HA. This water filled crosslinked HA gel forms a smooth film on the skin and continuously delivers the bound water, so it gives long-term moisturizing benefits.

What-it-does: buffering

It’s a little helper ingredient that helps to set the pH of a cosmetic formulation to be just right.

We don't have description for this ingredient yet.

What-it-does: viscosity controlling

We don't have description for this ingredient yet.

What-it-does: moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It's a sweet tasting sugar substitute that helps your skin to hold onto water when used in cosmetic products. It also helps to thicken up products and give them a bit more slip. 

What-it-does: buffering

Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA. 

So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh. 

Also-called: Argireline, Acetyl Hexapeptide-3 | What-it-does: cell-communicating ingredient, moisturizer/humectant

If you see a cosmetic product that claims that it has "Botox-like effect" then two things are almost certain: one, the product overpromises and two, it contains Argireline. 

So this one is the famous peptide that's marketed by its manufacturer as the "Botox in a jar". The basis for this claim is that it targets the same wrinkle forming mechanism (wrinkles caused by facial muscle movement) as Botox, but the way it works is very different. In addition, the extent to which it can prevent muscles from contracting (and to smooth wrinkles) is very different (otherwise why would anyone use still Botox?). 

What-it-does: antioxidant

We don't have description for this ingredient yet.

Also-called: SNAP-8, Acetyl Glutamyl Heptapeptide-1 | What-it-does: cell-communicating ingredient, moisturizer/humectant

A newer and, molecule-wise, somewhat bigger version of the famous "Botox-like" peptide called Acetyl Hexapeptide-8 or Argireline. Just like Argireline, Acetyl Octapeptide-3 is also claimed to influence the muscle contraction process that results in a more relaxed and line-free face, especially around the forehead and the eyes.  

While Argireline counts as a pretty well-proven peptide, with multiple studies confirming its anti-wrinkle efficacy, we cannot say the same for Acetyl Octapeptide-3. What we have is the manufacturer's claim that comparing 10% Argireline with 10% SNAP-8 solution (that means 0.005% pure peptide powder) the SNAP-8 peptide did a bit better as it reduced wrinkles by 34.98% vs 27.05% reduction for Argireline (twice a day use for 28 days on 17 women). 

Also-called: Thymulen 4 | What-it-does: cell-communicating ingredient

A four amino acid peptide that is claimed to mimic the youth hormone called thymopoietin. It works by compensating the loss of thymic factors that come with age and is thought to stimulate the skin immune defenses and to help the skin regenerate

A relatively new, four amino acid peptide that promises to help combat hair loss alongside red clover extract as part of the trademarked technology Capixyl

The main thing of  Acetyl Tetrapeptide-3 is to stimulate the synthesis of key Extra Cellular Matrix (aka ECM, the gooey stuff between cells that make up the framework of our skin) components in the scalp.  According to the manufacturer’s lab studies, the expression of type III collagen increased by 65% and the expression of laminins (anchoring proteins found in the ECM) was up a massive 285%, resulting in a stronger ECM bed for hair anchoring.

Also-called: EYESERYL | What-it-does: cell-communicating ingredient, moisturizer/humectant

A four amino acid peptide that is claimed to improve puffy eye bags via its anti-oedema and anti-glycation effects.

To back this claim up, the manufacturer created an in-vivo study with 20 volunteers using 10% of EYESERYL (that comes down to 0.01% (!) of the pure peptide) and found that by day 15, 70% of the volunteers improved, while 95% of the volunteers improved by the end of the study (60 days). About third of them improved only slightly, third of them showed an ok improvement and third showed a good improvement. They also have pretty convincing before and after photos, so we can tell you that for the lucky ones, the improvement can be real and visible.

We don't have description for this ingredient yet.

Carnosine - goodie

Though its name does not reveal it, Carnosine is a peptide, a small, two amino acid (β-Ala-His) one. It is naturally present in high concentrations in muscle and brain tissues, but the one used in cosmetic products is biomimetic, meaning that it is synthetically produced in a lab to copy the natural thing. 

A 2017 review paper on topical peptides writes about Carnosine that it is a "well-documented aqueous antioxidant with wound healing activity".  

Also-called: GHK-Cu, Copper Peptide | What-it-does: cell-communicating ingredient, soothing, antioxidant
  • GHK-Cu is a copper-peptide complex found naturally in yucky bodily fluids (plasma, saliva, and urine)
  • It has unique wound healing properties by stimulating the breakdown of unhealthy, too large collagen in scar tissue and stimulating nice and healthy collagen production afterwards
  • It stimulates the production of several important skin-identical ingredients (e.g. collagen, elastin, and glycosaminoglycans)
  • It has significant anti-inflammatory and antioxidant effect
  • There are a few promising studies showing GHK-Cu can improve skin elasticity, clarity, firmness and reduce lines and wrinkles
  • It can improve hair growth by enlarging hair follicles (and bigger follicles produce longer, thicker hair)
  • There are some urban legends about possible overdosing or facial hair problems (read more in geeky details)
Read all the geeky details about Copper Tripeptide-1 here >>

We don't have description for this ingredient yet.

Also-called: Matrixyl, Pal-KTTKS, Formerly Palmitoyl Pentapeptide-3 | What-it-does: cell-communicating ingredient

A pretty famous and better-researched peptide consisting of five amino acids (the building blocks of all proteins). It was created in a joint effort by the French ingredient supplier, Sederma and the cosmetics industry big shot, Procter&Gamble.

The amino acid sequence of the peptide is lysine–threonine–threonine–lysine–serine (KTTKS). Sometimes, it's also called collagen pentapeptide, as it's a subfragment of skin-structure-giving type I collagen. The KTTKS amino sequence is then attached for better oil solubility and skin penetration to palmitic acid and BOOM; we get Palmitoyl Pentapeptide-4. 

Also-called: Part of Matrixyl 3000, Pal-GHK, Formerly also Palmitoyl Oligopeptide | What-it-does: cell-communicating ingredient

A really famous peptide that is part of Matrixyl 3000, the most sold peptide complex in the word. Before we go and find out what the big deal with Matrixyl 3000 is, let's just focus on Palmitoyl Tripeptide-1 itself for a bit.

It's a small three amino acid (they are the building blocks of all proteins) peptide with the amino sequence of glycine-histidine-lysine, or GHK. GHK is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration. 

Also-called: Syn-Coll | What-it-does: cell-communicating ingredient

A tripeptide (three amino acids attached to each other: Lys-Val-Lys) that's claimed to protect and boost collagen and improve skin texture.

The manufacturer did an in-vivo (made on real people) study with 45 volunteers and found that used twice daily for 84 days 1% and 2.5% Syn-Coll reduces the appearance of wrinkles by 7 and 12% respectively. In another study (also by the manufacturer) with 33 female Chinese volunteers, 77% of the participants felt that Syn-Coll visibly improved the firmness and elasticity of the skin after 4 weeks. What's more, 60% of the participants also noticed a reduction in the look of the pore size also after 4 weeks of treatment. 

What-it-does: emulsion stabilising

A 100% vegetable origin emulsifier that usually comes to the formula with its buddy called C12-20 Alkyl Glucoside. The duo is trade-named Montanov L and works as an effective oil in water emulsifier. It creates ultra-soft, light texture, has excellent dermo-compatibility and is readily biodegradable.

Chemically speaking, it is a mixture of fatty alcohols with 14 to 22 carbon atoms in their fatty chains. 

What-it-does: viscosity controlling, emulsion stabilising | Irritancy: 0 | Comedogenicity: 1

A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula.  It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.

What-it-does: emollient, viscosity controlling, emulsifying, emulsion stabilising, surfactant/cleansing | Irritancy: 1 | Comedogenicity: 2

An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.  

It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols.  Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.

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