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What-it-does: antioxidant, soothing


One of the main biologically active components of the famous medicinal plant, Centella Asiatica, aka Gotu Kola. It has pretty well established wound healing, skin soothing and antioxidant activities.

There is also a study by La Roche Posay (belongs to L'Oreal) that examined the anti-aging effects of 5% Vitamin C combined with 0.1% Madecassoside. They mention that " Madecassoside is known to induce collagen expression
and ⁄ or to modulate inflammatory mediators thus might  prevent and correct some signs of aging.
" The surprisingly long, 6-month study observed "significant improvement of the clinical score for deep and superficial wrinkles, suppleness, firmness, roughness, and skin hydration", but Vitamin C in itself is already an anti-aging superstar, so it is hard to know how much Madecassoside did. 

If you are into Gotu Kola, read more here >> 

Show me some proof

  • Liu, Mei, et al. "Madecassoside isolated from Centella asiatica herbs facilitates burn wound healing in mice." Planta medica 74.08 (2008): 809-815.
  • Haftek, Marek, et al. "Clinical, biometric and structural evaluation of the long‐term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin." Experimental dermatology 17.11 (2008): 946-952.
  • Sasmita, Andrew Octavian, et al. "Madecassoside activates anti‑neuroinflammatory mechanisms by inhibiting lipopolysaccharide‑induced microglial inflammation." International journal of molecular medicine 41.5 (2018): 3033-3040.

Products with Madecassoside

A'pieu Madecassoside Ampoule innisfree Aloe Revital Skin Mist innisfree Aloe Revital Soothing Gel Vice Reversa Micro-Needling Pimple Patches 2Sol Elixir Propolis Serum Etude House Soon Jung Ph 5.5 Relief Toner PACKage Don't Worry Healing Mask Etude House Soonjung 5-Panthensoside Cica Balm Etude House Soonjung Ph5.5 Relief Toner Sidmool Madagascar Centella Asiatica Toner Umoua Skin Revitalization Anti-Acne Skin Balancing System A'pieu Madecassoside Fluid Etude House Cica Balance 5.5 Gel Cleanser Etude House Soon Jung 10 Free Moist Emulsion Neulii Cicapepta Repair Serum Purito Snail Repair Advanced Serum Sidmool Good Spot Cream innisfree Aloe Revital Sleeping Mask Etude House Soonjung Ph 6.5 Whip Cleanser Olivarrier Dual Moist Hyaluron Essence Olivarrier Dual Moist Toning Lotion Olivarrier Dual Moist Toning Lotion The Face Shop Dr.Belmeur Cica Peptite Ampoule innisfree Bija Cica Balm A'pieu Madecassoside Cica Gel CNP Laboratory 2-Step Propolis Energy Ampule Mask CNP Laboratory Mugener Ampule CNP Laboratory Propolis Energy Ampule Etude House Ac Clean Up Pink Powder Spot Neogen A-Clear Aid Soothing Pink Eraser BANOBAGI Milk Thistle Repair Toner CN Formulator Curcumin Essence Chemist Confessions Aquafix Neogen Dermalogy Real Cica Pad Neogen Real Cica Micellar Cleansing Water Sidmool Macenna 115 Ampoule Sioris A Calming Day Ampoule The Inkey List Snow Mushroom innisfree The Minimum Facial Cleanser For Sensitive Skin Benton Cacao Moist And Mild Toner Etude House Soon Jung 2X Barrier Intensive Cream Etude House Soon Jung Moist Relief All In One Gel IOPE Derma Repair Cica Cream La Roche-Posay Cicaplast Gel B5 Pro-Recovery Skincare La Roche-Posay Cicaplast Pro-Recovery Skincare La Roche-Posay Hyalu B5 Hyaluronic Acid Serum Natural Pacific Greenpair Plus Clear Serum Peach and Lily Glass Skin Refining Serum Torriden Cellmazing Centellareal Toner A'pieu Madecassoside Cica Gel