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Madecassoside

goodie
What-it-does: antioxidant, soothing

Details

One of the main biologically active components of the famous medicinal plant, Centella Asiatica, aka Gotu Kola. It has pretty well established wound healing, skin soothing and antioxidant activities.

There is also a study by La Roche Posay (belongs to L'Oreal) that examined the anti-aging effects of 5% Vitamin C combined with 0.1% Madecassoside. They mention that " Madecassoside is known to induce collagen expression
and ⁄ or to modulate inflammatory mediators thus might  prevent and correct some signs of aging.
" The surprisingly long, 6-month study observed "significant improvement of the clinical score for deep and superficial wrinkles, suppleness, firmness, roughness, and skin hydration", but Vitamin C in itself is already an anti-aging superstar, so it is hard to know how much Madecassoside did. 

If you are into Gotu Kola, read more here >> 

Show me some proof

  • Liu, Mei, et al. "Madecassoside isolated from Centella asiatica herbs facilitates burn wound healing in mice." Planta medica 74.08 (2008): 809-815.
  • Haftek, Marek, et al. "Clinical, biometric and structural evaluation of the long‐term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin." Experimental dermatology 17.11 (2008): 946-952.
  • Sasmita, Andrew Octavian, et al. "Madecassoside activates anti‑neuroinflammatory mechanisms by inhibiting lipopolysaccharide‑induced microglial inflammation." International journal of molecular medicine 41.5 (2018): 3033-3040.

Products with Madecassoside

2Sol Elixir Propolis Serum Etude House Soonjung 5-Panthensoside Cica Balm Etude House Soonjung Ph5.5 Relief Toner Sidmool Madagascar Centella Asiatica Toner A'pieu Madecassoside Fluid Etude House Cica Balance 5.5 Gel Cleanser Etude House Soon Jung 10 Free Moist Emulsion Purito Snail Repair Advanced Serum Sidmool Good Spot Cream innisfree Aloe Revital Sleeping Mask Etude House Soonjung Ph 6.5 Whip Cleanser Olivarrier Dual Moist Hyaluron Essence Olivarrier Dual Moist Toning Lotion Olivarrier Dual Moist Toning Lotion innisfree Bija Cica Balm CNP Laboratory 2-Step Propolis Energy Ampule Mask CNP Laboratory Mugener Ampule CNP Laboratory Propolis Energy Ampule Chemist Confessions Aquafix Neogen Dermalogy Real Cica Pad Neogen Real Cica Micellar Cleansing Water Sioris A Calming Day Ampoule Etude House Soon Jung 2X Barrier Intensive Cream Etude House Soon Jung Moist Relief All In One Gel IOPE Derma Repair Cica Cream La Roche-Posay Cicaplast Gel B5 Pro-Recovery Skincare La Roche-Posay Cicaplast Pro-Recovery Skincare La Roche-Posay Hyalu B5 Hyaluronic Acid Serum Natural Pacific Greenpair Plus Clear Serum Peach and Lily Glass Skin Refining Serum Torriden Cellmazing Centellareal Toner A'pieu Madecassoside Cica Gel Etude House Cica Balance 5.5 Lip And Eye Remover La Roche-Posay Cicaplast Baume B5 La Roche-Posay Cicaplast Baume B5 Nacific Green Pair Plus Clear Toner Sidmool Madagascar Real Moisture Cream innisfree Minimum For Sensitive Skin Cleansing Milk innisfree Truecare Cica Intensive Balm Sidmool Dr. Galatok Galatokside Real N.M.F Barrier Serum Atopalm Real Barrier Aqua Soothing Toner Benton Cacao Moist And Mild Cream Benton Goodbye Redness Centella Mask Pack 23G CNP Laboratory Green Propolis Anti-Oxidant Ampule Healgel Intensive Olivarrier Gentle Glow Seed Polishing Mask Atopalm Real Barrier Aqua Soothing Ampoule Dr Dennis Gross Hyaluronic Marine Dew It All Eye Gel Allies of Skin Bright Future Overnight Facial COSRX Cooling Aqua Facial Mist