Rejuveon

Pdrn 1000+ Cream

An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.  

It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols.  Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.

A vegetable-based emulsifier that helps the oily and watery parts of the formula to mix nicely together. It is compatible with a bunch of cosmetic oils as well as active ingredients and its specialty is creating emulsions with super high heat and freeze stability (from -25 °C and +50 °C).

A super commonly used 5 unit long, cyclic structured silicone that is water-thin and does not stay on the skin but evaporates from it (called volatile silicone). Similar to other silicones, it gives skin and hair a silky, smooth feel. 

It's often combined with the non-volatile (i.e. stays on the skin) dimethicone as the two together form a water-resistant, breathable protective barrier on the skin without a negative tacky feel.

It's a type of glycol that - according to the manufacturer - is an extremely good replacement for other glycols like propylene or butylene glycol. Its main job is to be a solvent, but it has also very good antimicrobial properties and acts as a true preservative booster. Also helps with skin hydration without stickiness or tacky feel.

• A multi-functional skincare superstar with several proven benefits for the skin
• Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
• Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
• Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
• Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis

A common multi-tasker fatty acid. It makes your skin feel nice and smooth (emollient), gives body to cream type products and helps to stabilize water and oil mixes (aka emulsions).

Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.

As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity. 

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A PEG-modified self-emulsifying crosslinked silicone elastomer surfactant that helps water to mix nicely with silicone oils, aka a water in silicone emulsifier. It creates highly stable micelle structures that break upon application of the product so it is ideal for  “water drop” like cream formulations.

A corn sugar derived, water-soluble, pale yellow syrup, that nicely moisturizes the skin. It has a light and smooth skin feel, it is non-tacky, and it can improve the after-feel of the formula. It is also mild and gentle, popular in sensitive skin formulas.

A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.

Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.

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A very common water-loving surfactant and emulsifier that helps to keep water and oil mixed nicely together. 

It's often paired with glyceryl stearate - the two together form a super effective emulsifier duo that's salt and acid tolerant and works over a wide pH range. It also gives a "pleasing product aesthetics", so no wonder it's popular.

A light-feeling, volatile (meaning it does not absorb into the skin but evaporates from it) silicone that gives skin a unique, silky and non-greasy feel. It has excellent spreading properties and leaves no oily residue or build-up. 

The salt form of one of the main anti-inflammatory ingredients in the licorice plant, monoammonium glycyrrhizinate. It’s a yellowish powder with a nice sweet smell. 

It’s used mainly for its soothing and anti-inflammatory properties, but according to manufacturer info, it’s also sebum regulating so it's a perfect ingredient for problem skin products. 

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A fatty acid that can be found naturally in the skin. In fact, it's the most common saturated fatty acid found in animals and plants.

As for skincare, it can make the skin feel nice and smooth in moisturizers (emollient) or it can act as a foam building cleansing agent in cleansers. It's also a very popular ingredient in shaving foams. 

It's a little helper ingredient that helps to set the pH of the products to be right. It has an alkaline pH and can neutralize acidic ingredients.

A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives. 

It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

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Centella Asiatica - or sometimes also called Gotu Kola or Cica - has been used in folk medicine for hundreds of years. It’s traditionally used to improve small wounds, burns and scratches and it’s also a well known anti-inflammatory agent for eczema.

Recently science has taken an interest in Gotu Kola as well and it turns out it really has many active compounds with several benefits. Just for hard-core geeks, the main biologically active compounds are pentacyclic triterpenoid saponins called asiaticoside, madecassoside, asiatic and madecassic acid (also called centellosides).

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A glycerin-derived gentle cleansing agent that is described as being skin and eye-friendly, and not leaving the skin dry or tight. It's also used as a co-emulsifier or solubilizer that helps to blend small amounts of oily things into water-based products. 

Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.

It is typically used in tiny amounts, around 0.1% or less.

An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid). 

Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier. 

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One of the main biologically active components of the famous medicinal plant, Centella Asiatica, aka Gotu Kola. It has well established wound healing, skin-soothing and antioxidant activities.

There is also a study by La Roche Posay (belongs to L'Oreal) that examined the anti-aging effects of 5% Vitamin C combined with 0.1% Madecassoside. They mention that " Madecassoside is known to induce collagen expression and ⁄ or to modulate inflammatory mediators thus might  prevent and correct some signs of aging." The surprisingly long, 6-month study observed "significant improvement of the clinical score for deep and superficial wrinkles, suppleness, firmness, roughness, and skin hydration", but Vitamin C in itself is already an anti-aging superstar, so it is hard to know how much Madecassoside did. 

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A sugar beet-derived amino acid derivative with nice skin protection and moisturization properties. Betaine's special thing is being an osmolyte, a molecule that helps to control cell-water balance.  It is also a natural osmoprotectant, meaning that it attracts water away from the protein surface and thus protects them from denaturation and increases their thermodynamic stability. 

It also gives sensorial benefits to the formula and when used in cleansers, it helps to make them milder and gentler. 

Super common soothing ingredient. It can be found naturally in the roots & leaves of the comfrey plant, but more often than not what's in the cosmetic products is produced synthetically. 

It's not only soothing but it' also skin-softening and protecting and can promote wound healing.

The chemically chopped up version of the big protein molecule, collagen. It is often derived from fish or bovine sources and works as a nice moisturizer and humectant that helps the skin to hold onto water.  

To understand a bit more what Hydrolyzed Collagen is, you have to know that proteins are large chains of amino acids connected with so-called peptide bonds. These bonds can be broken up when a water molecule is added and the resulting thing is a mix of shorter length amino acids, also called peptides. So Hydrolyzed Collagen is not really collagen, it is rather an undefined and varying mix of largish peptides. Based on a manufacturer's data, the whole, soluble collagen has an average molecular weight of 300 000 Da, while this chopped up mixture has an average MW of 12 000 Da (still pretty big). 

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Cellulose is an important component of the cell walls of green plants and it's the most abundant natural polymer (big molecule from repeated subunits) on Earth. If the polymer structure is not too big (less than 200 repeated units), cellulose becomes microcrystalline cellulose.

In skin care, it comes as a fine or less fine white powder. The less fine (bigger particle size) version is used as a gentle scrubbing agent (a nice natural, biodegradable alternative to now banned plastic polyethylene) and the ultra fine version is used as a helper ingredient that gives a super-silky, soft touch, reduces tackiness or greasiness and can also be used as a mattifying agent.

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A 100% plant derived, natural (Ecocert approved) multi-functional ingredient that has emollient and moisturizing properties, can work as a co-emulsifier (meaning that next to other emulsifiers it can help water and oil to mix)  and even more importantly has a strong antimicrobial activity. 

Thanks to this last thing, it allows a lower percentage of traditional preservative or it might even be able to completely replace them. 

A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula.  It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.

A semi-essential (infants cannot synthesize it, but adults can) amino acid that is one of the primary building blocks of hair keratin and skin collagen. It's a natural moisturizing factor, a skin hydrator and might also help to speed up wound healing. 

Arginine usually has a positive charge (cationic) that makes it substantive to skin and hair (those are more negatively charged surfaces) and an excellent film former.  Thanks to the positive charge, it also creates a complex with AHAs (AHAs like to lose a hydrogen ion and be negatively charged, so the positive and the negative ions attract each other) that causes a "time-release AHA effect" and reduces the irritation associated with AHAs. 

A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent and a broad spectrum antimicrobial. According to manufacturer info, it's also a moisturizer and helps to make the product feel great on the skin. It works synergistically with preservatives and helps to improve water-resistance of sunscreens. 

It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol. 

The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.

It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated  (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life. 

It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy.

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You probably know yeast from the kitchen where you put it into milk with a little sugar and then after a couple of minutes brownish bubbles form. That is the fungi fermenting the sugar. 

As for skin care, yeast contains beta-glucan that is a great soothing ingredient and also a mild antioxidant.  The yeast extract itself is a silky clear liquid that has some great moisturizing, skin protecting and film-forming properties on the skin. 

A clear, colorless liquid that works as a solvent and viscosity decreasing ingredient. It also has great skin-moisturizing abilities. 

The big brother of glycerin. It's also a natural moisturizing factor that reduces water evaporation from the upper layer of the skin and helps to keep water in the skin so that it stays nicely hydrated.

Compared to glycerin, it has a larger molecular structure (kind of a double glycerin). Thanks to this, it penetrates slower into the skin but gives longer lasting moisture and less sticky, better skin-feel.

Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved. 

It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. 

Lactobacillus ferment is an interesting probiotic ingredient with some promising properties. 

First, according to a 2009 Estee Lauder patent, it’s a DNA repair enzyme and it can help to protect the skin against environmental aggressors.

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The flower water coming from the flowers of the Damask Rose. In general, flower waters (also called hydrosols) are diluted versions of essential oils coming from the same plant. They contain the same components but in much-reduced concentrations.

Similar to its big sister, rose oil, rose water also has a lovely, relaxing scent. It contains some antioxidant and antimicrobial compounds, as well as some fragrant components. 

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We don't have description for this ingredient yet.

The sodium salt form of skincare superstar, vitamin C. If you do not know what the big fuss about vitamin C is, you are missing out and you have to click here and read all the geeky details about it.

Pure vitamin C (aka ascorbic acid, AA) is great and all, but its lack of stability is a big challenge for the cosmetics industry. One solution is to create stable derivatives that can be absorbed into the skin, convert there to AA and do all the magic AA is proven to do (which is being an antioxidant, a collagen booster, and a skin brightener).

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We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Glutamic acid is a little molecule and non-essential (our body can synthesize it) amino acid with the important job of being a neurotransmitter in the human body meaning that it helps your nervous system work correctly. 

As for what it's doing in cosmetics, Glutamic acids' main thing (similar to other amino acids) is being a humectant moisturizer and skin-conditioning agent (sidenote: if you attach lots of glutamic acid molecules, you get polyglutamic acid that is claimed to be a better than hyaluronic acid humectant). It also seems to affect skin barrier repair, however, it is not clear-cut in which direction.

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A non-essential amino acid (the building blocks of skin proteins, like collagen or elastin), that the body can produce itself, but its production decreases with age. When you put it all over your face, it works as a moisturizer and maybe more. 

According to great skincare blog Futurederm, glycine might help with wound healing and tissue repair and when used together with other amino acids, leucine and proline it might improve wrinkles. 

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We don't have description for this ingredient yet.

Serine is an amino acid that most often comes to the formula as part of a moisturizing complex. It's a non-essential amino acid (meaning that our body can synthesize it) and serves as a water-binding ingredient.

In general, amino acids are great skincare ingredients that play an important role in proper skin hydration but there is not much info out there about what specifically serine can do for the skin.

A non-essential amino acid (a building block of skin proteins like collagen or elastin) that hydrates the skin.

A non-essential amino acid (meaning that our body can produce it) that's also one of the major building blocks of collagen. According to the Futurederm blog, it might be able to improve wrinkles when combined with other amino acids, glycine and leucine

An essential amino acid that's also a key building block of collagen and elastin. When taken orally, it helps the digestive and intestinal tracts function more smoothly and also helps the absorption of nutrients. As for skincare, it is not clear what it does other than being a skin hydrator. 

An essential amino acid (a building block of skin proteins like collagen) that our body cannot produce itself but has to take from external sources, like diet. 

It's a branched chain amino acid that is claimed to enhance energy, increase endurance and aid in muscle tissue recovery and repair when taken as a supplement. It's not clear what valine does when you put it on the skin, but as all amino acids, it must be at least a great skin hydrator.

A branch-chained, essential amino acid that can be found in things like almond, cashew or soy protein. When taken orally it may promote protein synthesis. As for skincare - like all the amino acids - it's a skin-identical ingredient and moisturizer. It also seems to be useful as a barrier repair ingredient.  

A non-essential amino acid  (important building block of collagen and elastin) that hydrates the skin. It is also used to set the pH of the cosmetic product (buffering).

We don't have description for this ingredient yet.

An essential amino acid that the body cannot produce itself but has to take from the diet. Combined with UVA exposure, phenylalanine is used in the treatment of vitiligo (a pigmentation disorder where patches of the skin lose the pigment).

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

A semi-essential (infants cannot synthesize it, but adults can) amino acid that is one of the primary building blocks of hair keratin and skin collagen. It's a natural moisturizing factor, a skin hydrator and might also help to speed up wound healing. 

Arginine usually has a positive charge (cationic) that makes it substantive to skin and hair (those are more negatively charged surfaces) and an excellent film former.  Thanks to the positive charge, it also creates a complex with AHAs (AHAs like to lose a hydrogen ion and be negatively charged, so the positive and the negative ions attract each other) that causes a "time-release AHA effect" and reduces the irritation associated with AHAs. 

A high-tech, South-Korean peptide that's made synthetically to be identical to the protein called Leu-Enkephalin. It's an 8 amino acid neuropeptide that helps the body to regulate how it responds to harmful things (like heat, cold, cutting or irritation). 

In general, neuropeptides are believed to be important in wound-healing and the manufacturer claims that Sh-Octapeptide-4 has strong anti-aging and anti-wrinkle effect as well as rejuvenating effect on aged hair tissue and follicles. 

We don't have description for this ingredient yet.

If you see a cosmetic product that claims that it has "Botox-like effect" then two things are almost certain: one, the product overpromises and two, it contains Argireline. 

So this one is the famous peptide that's marketed by its manufacturer as the "Botox in a jar". The basis for this claim is that it targets the same wrinkle forming mechanism (wrinkles caused by facial muscle movement) as Botox, but the way it works is very different. In addition, the extent to which it can prevent muscles from contracting (and to smooth wrinkles) is very different (otherwise why would anyone use still Botox?). 

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An anti-aging peptide that can visibly reduce the length and depth of wrinkles, at least according to its manufacturer. In vitro (meaning it was done in the lab, not on real people) studies show that it enhances epidermal regeneration, collagen type I and III synthesis as well as the synthesis of other important skin proteins.