Anti-aging Night Cream
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MANUFAKTURA Anti-aging Night CreamIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular.
A clear, colorless oil-like liquid that makes the skin feel smooth and nice (aka emollient) and it does so without it being greasy.
What's more, it can even reduce the heavy, greasy feel in products with high oil content. It's also fast-spreading meaning that it gives the formula a good, nice slip. It absorbs quickly into the skin and helps other ingredients to penetrate quicker and deeper.
Thanks to all this, it's one of the most commonly used emollients out there. There is just one little drawback: it has a high comedogenic index (5 out of 5...), so it might clog pores if you're prone to it.
Unless you live under a rock you must have heard about shea butter. It's probably the most hyped up natural butter in skincare today. It comes from the seeds of African Shea or Karite Trees and used as a magic moisturizer and emollient.
But it's not only a simple emollient, it regenerates and soothes the skin, protects it from external factors (such as UV rays or wind) and is also rich in antioxidants (among others vitamin A, E, F, quercetin and epigallocatechin gallate). If you are looking for rich emollient benefits + more, shea is hard to beat.
The emollient plant oil that comes from almonds. Similar to other plant oils, it is loaded with skin-nourishing fatty acids (oleic acid - 55-86% and linoleic acid 7-35%) and contains several other skin goodies such as antioxidant vitamin E and vitamin B versions.
It's a nice, basic oil that is often used due to its great smoothing, softening and moisturizing properties. It's also particularly good at treating dry brittle nails (source).
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
A vegetable-based emulsifier that helps the oily and watery parts of the formula to mix nicely together. It is compatible with a bunch of cosmetic oils as well as active ingredients and its specialty is creating emulsions with super high heat and freeze stability (from -25 °C and +50 °C).
We don't have description for this ingredient yet.
It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life.
It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy.
Another advantage of squalane is that it is pretty much compatible with all skin types and skin conditions. It is excellent for acne-prone skin and safe to use even if you have fungi-related skin issues, like seborrhea or fungal acne.
The unsaturated (with double bonds) and hence less stable version of Squalane is Squalene, you can read about it here >>
A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.
Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.
It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".
An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.
It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols. Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.
Jojoba is a drought resistant evergreen shrub native to South-western North America. It's known and grown for jojoba oil, the golden yellow liquid coming from the seeds (about 50% of the weight of the seeds will be oil).
At first glance, it seems like your average emollient plant oil: it looks like an oil and it's nourishing and moisturizing to the skin but if we dig a bit deeper, it turns out that jojoba oil is really special and unique: technically - or rather chemically - it's not an oil but a wax ester (and calling it an oil is kind of sloppy).
So what the heck is a wax ester and why is that important anyway? Well, to understand what a wax ester is, you first have to know that oils are chemically triglycerides: one glycerin + three fatty acids attached to it. The fatty acids attached to the glycerin vary and thus we have many kinds of oils, but they are all triglycerides. Mother Nature created triglycerides to be easily hydrolyzed (be broken down to a glycerin + 3 fatty acid molecules) and oxidized (the fatty acid is broken down into small parts) - this happens basically when we eat fats or oils and our body generates energy from it.
Mother Nature also created wax esters but for a totally different purpose. Chemically, a wax ester is a fatty acid + a fatty alcohol, one long molecule. Wax esters are on the outer surface of several plant leaves to give them environmental protection. 25-30% of human sebum is also wax esters to give us people environmental protection.
So being a wax ester results in a couple of unique properties: First, jojoba oil is extremely stable. Like crazy stable. Even if you heat it to 370 C (698 F) for 96 hours, it does not budge. (Many plant oils tend to go off pretty quickly). If you have some pure jojoba oil at home, you should be fine using it for years.
Second, jojoba oil is the most similar to human sebum (both being wax esters), and the two are completely miscible. Acne.org has this not fully proven theory that thanks to this, jojoba might be able to "trick" the skin into thinking it has already produced enough sebum, so it might have "skin balancing" properties for oily skin.
Third, jojoba oil moisturizes the skin through a unique dual action: on the one hand, it mixes with sebum and forms a thin, non-greasy, semi-occlusive layer; on the other hand, it absorbs into the skin through pores and hair follicles then diffuses into the intercellular spaces of the outer layer of the skin to make it soft and supple.
On balance, the point is this: in contrast to real plant oils, wax esters were designed by Mother Nature to stay on the surface and form a protective, moisturizing barrier and jojoba oil being a wax ester is uniquely excellent at doing that.
An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid).
Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier.
Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.
Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation.
If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.
As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily.
We don't have description for this ingredient yet.
It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.
As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution".
In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).
What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists.
If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
An anti-aging peptide that can visibly reduce the length and depth of wrinkles, at least according to its manufacturer. In vitro (meaning it was done in the lab, not on real people) studies show that it enhances epidermal regeneration, collagen type I and III synthesis as well as the synthesis of other important skin proteins.
Sunflower does not need a big intro as you probably use it in the kitchen as cooking oil, or you munch on the seeds as a healthy snack or you adore its big, beautiful yellow flower during the summer - or you do all of these and probably even more. And by even more we mean putting it all over your face as sunflower oil is one of the most commonly used plant oils in skincare.
It’s a real oldie: expressed directly from the seeds, the oil is used not for hundreds but thousands of years. According to The National Sunflower Association, there is evidence that both the plant and its oil were used by American Indians in the area of Arizona and New Mexico about 3000 BC. Do the math: it's more than 5000 years – definitely an oldie.
Our intro did get pretty big after all (sorry for that), so let's get to the point finally: sunflower oil - similar to other plant oils - is a great emollient that makes the skin smooth and nice and helps to keep it hydrated. It also protects the surface of the skin and enhances the damaged or irritated skin barrier. Leslie Bauman notes in Cosmetic Dermatology that one application of sunflower oil significantly speeds up the recovery of the skin barrier within an hour and sustains the results 5 hours after using it.
It's also loaded with fatty acids (mostly linoleic (50-74%) and oleic (14-35%)). The unrefined version (be sure to use that on your skin!) is especially high in linoleic acid that is great even for acne-prone skin. Its comedogen index is 0, meaning that it's pretty much an all skin-type oil.
Truth be told, there are many great plant oils and sunflower oil is definitely one of them.
- Primary fat-soluble antioxidant in our skin
- Significant photoprotection against UVB rays
- Vit C + Vit E work in synergy and provide great photoprotection
- Has emollient properties
- Easy to formulate, stable and relatively inexpensive
Beta-Glucan is a nice big molecule composed of many smaller sugar molecules (called polysaccharide). It’s in the cell walls of yeast, some mushrooms, seaweeds, and cereals.
It’s a real goodie no matter if you eat it or put it on your face. Eating it is anti-diabetic, anti-cancer, and even lowers blood cholesterol.
Putting it on your face also does a bunch of good things: it‘s shown to have intensive skin repairing & wound healing properties, it’s a mild antioxidant, a great skin soother, and moisturizer, and it even shows promising anti-aging benefits.
The manufacturer of the ingredient did a published study with 27 people and examined the effect of 0.1% beta-glucan. They found that despite the large molecular size the smaller factions of beta-glucan penetrate into the skin, even into the dermis (the middle layer of the skin where wrinkles form). After 8 weeks there was a significant reduction of wrinkle depth and height and skin roughness has also improved greatly.
Bottom line: Beta-glucan is a great ingredient, especially for sensitive or damaged skin. It soothes, moisturizes, and has some anti-aging magic properties.
It's a little helper ingredient coming from corn, rice or potato starch that can help to keep skin mat (absorbent), to stabilise emulsions, and to keep the product together (binding).
We don't have description for this ingredient yet.
Squalene is an oily liquid that originally comes from shark liver but luckily it can also be found in a couple of plant oils. Olive (0.6%), peanut (0.1%) and pumpkin (0.35%) oils contain it, though not in huge amounts.
What contains more of it, is the sebum (the oily stuff) that our skin produces. About 13% of human sebum is squalene, which means that it’s an important skin-identical ingredient and NMF (natural moisturizing factor).
Chemically speaking, it is an unsaturated (has double bonds) hydrocarbon (contains only carbon and hydrogen) molecule, that can undergo oxidation. On the pro side, this means that squalene can act as an antioxidant (while its no-double-bond version sister, squalane cannot), but on the con side, squalene is less stable and has a shorter shelf life.
This is probably the main reason why its no-double bond and hence more stable sister, squalane shows up more often on ingredient lists. Read about squalane here >>
Super common soothing ingredient. It can be found naturally in the roots & leaves of the comfrey plant, but more often than not what's in the cosmetic products is produced synthetically.
It's not only soothing but it' also skin-softening and protecting and can promote wound healing.
The sodium salt of lactic acid. It's a great skin moisturizer and also used to regulate the pH value of the cosmetic formula. It's a natural ingredient approved by both ECOCERT and COSMOS.
PCA stands for Pyrrolidone Carboxylic Acid and though it might not sound like it, it is a thing that can be found naturally in our skin. The sodium salt form of PCA is an important skin-identical ingredient and great natural moisturizer that helps the skin to hold onto water and stay nicely hydrated.
A non-essential amino acid (the building blocks of skin proteins, like collagen or elastin), that the body can produce itself, but its production decreases with age. When you put it all over your face, it works as a moisturizer and maybe more.
According to great skincare blog Futurederm, glycine might help with wound healing and tissue repair and when used together with other amino acids, leucine and proline it might improve wrinkles.
BTW, it's also a building block of a bunch of important and famous peptides, including copper-tripeptide-1, palmitoyl tripeptide-1 or palmitoyl hexapeptide-12.
Fancy name for fruit sugar. It has nice water-binding properties and helps to keep skin hydrated.
Yes, it's the thing that can be found naturally in pee. And in the skin. It is an awesome natural moisturizing factor, aka NMF. NMFs are important components that help the skin to hold onto water and keep it plump, elastic and hydrated. Urea makes up about 7% of NMFs next to other things such as amino acids (40%), PCA (12%) or Lactate (12%).
What makes urea special, is that it is not only a simple moisturizer, but it is thought to be a "small-molecule regulator of epidermal structure and function" meaning that it has a bunch of extra biological activities. It acts as a mild keratolytic agent (some of its moisturizing action is thought to come from urea's ability to break down bonds in the protein called filaggrin and thus freeing up amino acids in the skin), enhances antimicrobial peptide expression and improves skin barrier function.
Being a mild keratolytic agent and strong moisturizer means that high-percentage (10-40%) urea treatments are found effective in a bunch of skin disorders connected to excessive dryness and malfunctioning skin barrier such as ichthyosis, xerosis, psoriasis, eczema and seborrheic dermatitis.
Overall, just like glycerin, urea is a real oldie but a goodie, a nice ingredient in any moisturizer.
- A multi-functional skincare superstar with several proven benefits for the skin
- Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
- Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
- Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
- Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
- It’s the second most researched AHA after glycolic acid
- It gently lifts off dead skin cells to reveal newer, fresher, smoother skin
- It also has amazing skin hydrating properties
- In higher concentration (10% and up) it improves skin firmness, thickness and wrinkles
- Choose a product where you know the concentration and pH value because these two greatly influence effectiveness
- Don’t forget to use your sunscreen (in any case but especially so next to an AHA product)
Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.
BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.
It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive.
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA.
So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh.
There is also some research showing that citric acid with regular use (think three months and 20% concentration) can help sun-damaged skin, increase skin thickness and some nice hydrating things called glycosaminoglycans in the skin.
But according to a comparative study done in 1995, citric acid has less skin improving magic properties than glycolic or lactic acid. Probably that’s why citric acid is usually not used as an exfoliant but more as a helper ingredient in small amounts to adjust the pH of a formulation.
Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!).
If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.
Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!).
A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi.
It’s pH dependent and works best at acidic pH levels (3-5). It’s not strong enough to be used in itself so it’s always combined with something else, often with potassium sorbate.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.
Also, it's an effective deodorant and a medium spreading emollient.
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| what‑it‑does | solvent |
| what‑it‑does | emollient |
| what‑it‑does | emollient | perfuming |
| irritancy, com. | 3, 3-5 |
| what‑it‑does | emollient |
| what‑it‑does | emollient |
| irritancy, com. | 0, 1-3 |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | emulsifying |
| what‑it‑does | skin-identical ingredient | emollient |
| irritancy, com. | 0, 1 |
| what‑it‑does | emollient | emulsifying |
| irritancy, com. | 0, 1-2 |
| what‑it‑does | emollient | viscosity controlling | emulsifying | surfactant/cleansing |
| irritancy, com. | 1, 2 |
| what‑it‑does | emollient |
| irritancy, com. | 0, 0-2 |
| what‑it‑does | soothing | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | emollient |
| irritancy, com. | 0, 0 |
| what‑it‑does | antioxidant |
| irritancy, com. | 0-3, 0-3 |
| what‑it‑does | soothing | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | antioxidant | emollient |
| what‑it‑does | soothing |
| irritancy, com. | 0, 0 |
| what‑it‑does | buffering | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| what‑it‑does | cell-communicating ingredient | skin brightening | anti-acne | moisturizer/humectant |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | exfoliant | moisturizer/humectant | buffering |
| what‑it‑does | moisturizer/humectant | solvent |
| irritancy, com. | 0, 1 |
| what‑it‑does | viscosity controlling |
| what‑it‑does | buffering |
| what‑it‑does | perfuming |
| what‑it‑does | preservative |
| what‑it‑does | preservative |
| what‑it‑does | preservative |