UV Protection Cream SPF50+ Pa+++ C-pdrn 0.2%
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Rejuran UV Protection Cream SPF50+ Pa+++ C-pdrn 0.2%Ingredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
The emollient plant oil coming from the seeds of Pomegranate. The red fruit has lots of seeds (100-200 per fruit), but 7 kg of them are needed for 1 kg of oil. Among the many similar plant oils, Pomegranate oil is a really unique one, as its main fatty acid (60%) is a rare one called punic acid, a so-called conjugated fatty acid with three double bonds. It also contains the common linoleic (2-10%) and oleic acids (3-12%), but only in small amounts.
Punic acid is thought to be a biologically active compound, a powerful anti-inflammatory, and antioxidant agent. The oil itself is also claimed to have strong antioxidant properties as well as having excellent nourishing and moisturizing abilities. On top of that, we also found a research that examined Pomegranate as a cosmeceutical source and it concluded that the seed oil can nicely promote the regeneration of the epidermis (the top layer of the skin).
An oil-soluble chemical sunscreen agent that protects the skin from UVB (295-315 nm) with a peak protection at 306 nm. Homosalate is not a strong UV filter in and of itself (gives only SPF 4.3 protection at max. allowed 10% concentration) and it is not photostable (looses 10% of its SPF protection in 45 mins) so it always has to be combined with other sunscreens for proper protection. Its big advantage, though, is that it is a liquid and is excellent for dissolving other hard to solubilize powder sunscreen agents, like the famous Avobenzone.
Regarding Homosalate's safety profile, we do not have the best news. In-vitro (made in the labs) studies have shown that it might have some estrogenic activity. Do not panic, these studies were not conducted on real humans under real world conditions. Still, if you are a 'better safe than sorry' type, be careful when using Homosalate containing sunscreens long-term and full-body.
As of 2020, Homosalate is permitted to be used up to 10% in the EU and 15% in the US, but the EU is currently considering restricting it to only 1.4% (probably taking effect from 2022).
Jojoba is a drought resistant evergreen shrub native to South-western North America. It's known and grown for jojoba oil, the golden yellow liquid coming from the seeds (about 50% of the weight of the seeds will be oil).
At first glance, it seems like your average emollient plant oil: it looks like an oil and it's nourishing and moisturizing to the skin but if we dig a bit deeper, it turns out that jojoba oil is really special and unique: technically - or rather chemically - it's not an oil but a wax ester (and calling it an oil is kind of sloppy).
So what the heck is a wax ester and why is that important anyway? Well, to understand what a wax ester is, you first have to know that oils are chemically triglycerides: one glycerin + three fatty acids attached to it. The fatty acids attached to the glycerin vary and thus we have many kinds of oils, but they are all triglycerides. Mother Nature created triglycerides to be easily hydrolyzed (be broken down to a glycerin + 3 fatty acid molecules) and oxidized (the fatty acid is broken down into small parts) - this happens basically when we eat fats or oils and our body generates energy from it.
Mother Nature also created wax esters but for a totally different purpose. Chemically, a wax ester is a fatty acid + a fatty alcohol, one long molecule. Wax esters are on the outer surface of several plant leaves to give them environmental protection. 25-30% of human sebum is also wax esters to give us people environmental protection.
So being a wax ester results in a couple of unique properties: First, jojoba oil is extremely stable. Like crazy stable. Even if you heat it to 370 C (698 F) for 96 hours, it does not budge. (Many plant oils tend to go off pretty quickly). If you have some pure jojoba oil at home, you should be fine using it for years.
Second, jojoba oil is the most similar to human sebum (both being wax esters), and the two are completely miscible. Acne.org has this not fully proven theory that thanks to this, jojoba might be able to "trick" the skin into thinking it has already produced enough sebum, so it might have "skin balancing" properties for oily skin.
Third, jojoba oil moisturizes the skin through a unique dual action: on the one hand, it mixes with sebum and forms a thin, non-greasy, semi-occlusive layer; on the other hand, it absorbs into the skin through pores and hair follicles then diffuses into the intercellular spaces of the outer layer of the skin to make it soft and supple.
On balance, the point is this: in contrast to real plant oils, wax esters were designed by Mother Nature to stay on the surface and form a protective, moisturizing barrier and jojoba oil being a wax ester is uniquely excellent at doing that.
Unless you live under a rock you must have heard about shea butter. It's probably the most hyped up natural butter in skincare today. It comes from the seeds of African Shea or Karite Trees and used as a magic moisturizer and emollient.
But it's not only a simple emollient, it regenerates and soothes the skin, protects it from external factors (such as UV rays or wind) and is also rich in antioxidants (among others vitamin A, E, F, quercetin and epigallocatechin gallate). If you are looking for rich emollient benefits + more, shea is hard to beat.
A colorless to light yellowish oily liquid that works as a UVB (280-320nm) sunscreen filter with a peak absorbance at 306 nm. It's not a strong filter in itself, it's always used in combination with other sunscreen agents to further enhance the SPF and to solubilize other solid UV filters.
It has a good safety profile and is allowed to be used at a max concentration of 5% both in the US and in Europe (10% is allowed in Japan).
A chemical sunscreen agent that absorbs UVB and short UVA rays (280-350nm) with its peak protection at 288 nm. Unlike many other chemical sunscreens, it is highly stable but its UV absorbing abilities are weak so it always has to be combined with other sunscreen agents for proper protection. More often than not, it's used as a photostabilizer rather than a proper sunscreen agent as it can protect formulas nicely from UV damage.
Regarding safety, BP-3 is somewhat controversial. First, its molecules are small (228 Da) and very lipophilic (oil loving) and these properties result in very good absorption. The problem is that you want sunscreens on the top of your skin and not in your bloodstream, so for BP-3 this is a problem. In fact, it absorbs so well that 4 hours after application of a sunscreen product with BP-3, it can be detected in urine.
Another concern of BP-3 is that it shows some estrogenic activity, though it's probably not relevant when applied topically to the skin. Estrogenic activity was confirmed only in-vitro (in test tubes) and when taken orally by lab animals, and not when used topically as you would normally. In fact, a 2004 follow-up study to examine the estrogenic effect of sunscreens when used topically on the whole body found that "the endogenous levels of reproductive hormones were unaffected" (even though BP-3 could be detected both in plasma and urine, so its absorption is no doubt too good).
If that was not enough, Wikipedia claims that BP-3 is nowadays the most common allergen found in sunscreens, and the always-trustworthy smartskincare writes that "[benzophenones] have been shown in some studies to promote the generation of potentially harmful free radicals".
On the up side, sunscreens are pretty well regulated in several parts of the world, and BP-3 is considered "safe as used" and is an allowed sunscreen agent everywhere. It can be used in concentrations of up to 10% in the EU and up to 6% in the US.
Overall, BP-3 is probably our least favorite sunscreen agent and we prefer sunscreens without it. However, if you find a formula that you love and contains BP-3, we do not think that you should throw it away. A sunscreen with BP-3 is definitely better than no sunscreen.
The famous Avobenzone. It is a special snowflake as it is the only globally available chemical sunscreen agent that provides proper UVA protection (in the US, new generation sunscreen agents are not approved because of impossible FDA regulations). It is the global gold standard of UVA protection and is the most used UVA sunscreen in the world.
It gives very good protection across the whole UVA range (310-400 nm that is both UVA1 and UVA2) with a peak protection at 360 nm. The problem with it, though, is that it is not photostable and degrades in the sunlight. Wikipedia says that avobenzone loses 36% of its UV-absorption capacity after just one hour of sunlight (yep, this is one of the reasons why sunscreens have to be reapplied after a few hours).
The cosmetic's industry is trying to solve the problem by combining avobenzone with other UV filters that enhance its stability (like octocrylene, Tinosorb S or Ensulizole) or by encapsulating it and while both solutions help, neither is perfect. Interestingly, the combination of avobenzone with mineral sunscreens (that is titanium dioxide and zinc oxide) is not a good idea. In the US, it is flat out prohibited as avobenzone becomes unstable when combined with mineral sunscreens.
As for safety, avobenzone has a pretty good safety profile. It counts as non-irritating, and unlike some other chemical sunscreens, it shows no estrogenic effect. The maximum concentration of avobenzone permitted is 5% in the EU and 3% in the US.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
An oil-soluble chemical sunscreen agent that protects skin in the UVB and somewhat in the UVA II range with a peak absorption of 304 nm. Its protection is not strong enough on its own but it is quite photostable (loses 10% of SPF protection in 95 mins) and is often used to stabilize other photo-unstable UV-filters, for example, Avobenzone. It is also often used to improve the water resistance of the products.
Octocrylene's safety profile is generally quite good, though a review study in Contact Dermatitis reports an "increasing number of patients with photo contact allergy to octocrylene." Mainly adults with ketoprofen-sensitivity and children with sensitive skin are affected, so if you have a small kid, it is probably better to use octocrylene-free sunscreens.
Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.
As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity.
As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types).
An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid).
Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier.
Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.
Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation.
If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.
As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
Aloe Vera is one of today’s magic plants. It does have some very nice properties indeed, though famous dermatologist Leslie Baumann warns us in her book that most of the evidence is anecdotal and the plant might be a bit overhyped.
What research does confirm about Aloe is that it’s a great moisturizer and has several anti-inflammatory (among others contains salicylates, polysaccharides, magnesium lactate and C-glucosyl chromone) as well as some antibacterial components. It also helps wound healing and skin regeneration in general. All in all definitely a goodie.
- Green tea is one of the most researched natural ingredients
- The active parts are called polyphenols, or more precisely catechins (EGCG being the most abundant and most active catechin)
- There can be huge quality differences between green tea extracts. The good ones contain 50-90% catechins (and often make the product brown and give it a distinctive smell)
- Green tea is proven to be a great antioxidant, UV protectant, anti-inflammatory, anticarcinogenic and antimicrobial
- Because of these awesome properties green tea is a great choice for anti-aging and also for skin diseases including rosacea, acne and atopic dermatitis
When you hear oatmeal, you probably think of breakfast, but the finely ground version of whole oat kernels, aka colloidal oatmeal, can do good things for your skin, especially if it's dry, itchy or prone to skin-rashes or eczema.
Oat is loaded with compounds good for the body, inside or outside, such as soothing agent beta-glucan (5%), lipids (3-11%) including barrier repairing omega-3 and 6 fatty acids or phenolic antioxidant and anti-inflammatory agents (avenanthramides).
The soothing, antioxidant and skin-protecting abilities of oat are so well-established that it is an active natural ingredient covered by the FDA OTC Skin Protectant monograph in the US, meaning that colloidal oatmeal can be claimed as an active ingredient on the INCI list and Aveeno is a mass-market brand built around oat-containing products.
If your skin is dry, irritated, inflamed or eczema-prone, colloidal oatmeal is something to try.
A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular.
Squalene is an oily liquid that originally comes from shark liver but luckily it can also be found in a couple of plant oils. Olive (0.6%), peanut (0.1%) and pumpkin (0.35%) oils contain it, though not in huge amounts.
What contains more of it, is the sebum (the oily stuff) that our skin produces. About 13% of human sebum is squalene, which means that it’s an important skin-identical ingredient and NMF (natural moisturizing factor).
Chemically speaking, it is an unsaturated (has double bonds) hydrocarbon (contains only carbon and hydrogen) molecule, that can undergo oxidation. On the pro side, this means that squalene can act as an antioxidant (while its no-double-bond version sister, squalane cannot), but on the con side, squalene is less stable and has a shorter shelf life.
This is probably the main reason why its no-double bond and hence more stable sister, squalane shows up more often on ingredient lists. Read about squalane here >>
A so-called fatty (the good, non-drying kind of) alcohol that does all kinds of things in a skincare product: it makes your skin feel smooth and nice (emollient), helps to thicken up products and also helps water and oil to blend (emulsifier). Can be derived from coconut or palm kernel oil.
An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.
It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols. Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.
It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version.
According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E.
A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.
Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.
It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".
You might know licorice as a sweet treat from your childhood, but it's actually a legume that grows around the Mediterranean Sea, the Middle East, central and southern Russia. It's sweet and yellow and not only used for licorice all sorts but it's also a skincare superstar thanks to two magic properties:
Nr. 1 magic property is that it has skin-lightening or to say it another way depigmenting properties. The most active part is called glabridin. The topical application (meaning when you put it on your face) of 0.5% glabridin was shown to inhibit UVB caused pigmentation of guinea pigs. Another study even suggested that licorice is more effective than the gold standard skin-lightening agent hydroquinone. All in all, licorice is considered to be one of the safest skin lightening agents with the fewest side effects.
There is just one catch regarding glabridin and licorice: the amount of glabridin in commercial licorice extracts can vary a lot. We have seen extracts with only 4% glabridin as well as 40% glabridin. The latter one is a very-very expensive ingredient, so if you are after the depigmenting properties try to choose a product that boasts its high-quality licorice extract.
Nr. 2 magic property is that licorice is a potent anti-inflammatory. Glabridin has also some soothing properties but the main active anti-inflammatory component is glycyrrhizin. It’s used to treat several skin diseases that are connected to inflammation including atopic dermatitis, rosacea or eczema.
Oh, and one more thing: glabridin seems to be also an antioxidant, which is just one more reason to be happy about licorice root extract on an ingredient list.
Bottom line: Licorice is a great skincare ingredient with significant depigmenting, anti-inflammatory and even some antioxidant properties. Be happy if it's on the ingredient list. :)
If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.
Also, it's an effective deodorant and a medium spreading emollient.
It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol.
The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.
It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.
As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution".
In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).
What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists.
If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
We don't have description for this ingredient yet.
A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi.
It’s pH dependent and works best at acidic pH levels (3-5). It’s not strong enough to be used in itself so it’s always combined with something else, often with potassium sorbate.
Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!).
If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.
Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!).
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| what‑it‑does | solvent |
| what‑it‑does | antioxidant | emollient |
| what‑it‑does | sunscreen |
| what‑it‑does | emollient |
| irritancy, com. | 0, 0-2 |
| what‑it‑does | emollient |
| what‑it‑does | sunscreen |
| irritancy, com. | 0, 0 |
| what‑it‑does | sunscreen |
| irritancy, com. | 0, 0 |
| what‑it‑does | sunscreen |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | sunscreen |
| what‑it‑does | emollient |
| irritancy, com. | 0, 1 |
| what‑it‑does | soothing | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | soothing | moisturizer/humectant |
| what‑it‑does | antioxidant | soothing |
| what‑it‑does | antioxidant | soothing | emollient | abrasive/scrub |
| what‑it‑does | emollient |
| what‑it‑does | skin-identical ingredient | antioxidant | emollient |
| what‑it‑does | emollient | viscosity controlling |
| irritancy, com. | 2, 2 |
| what‑it‑does | emollient | viscosity controlling | emulsifying | surfactant/cleansing |
| irritancy, com. | 1, 2 |
| what‑it‑does | antioxidant |
| irritancy, com. | 0, 0 |
| what‑it‑does | emollient | emulsifying |
| irritancy, com. | 0, 1 |
| what‑it‑does | soothing | skin brightening |
| what‑it‑does | preservative |
| what‑it‑does | moisturizer/humectant | emollient |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | preservative |
| what‑it‑does | preservative |
| what‑it‑does | perfuming |