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First Lab Probiotic Cream

Probiotic Cream

Maintain a good bacteria on your skin, skin Brightening, pore and wrinkle improvement. Safe for Sensitive Skin and Eczema Friendly.
Uploaded by: dsfvn on

Highlights

#alcohol-free
Alcohol Free

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Ingredient name what-it-does irr., com. ID-Rating
Water solvent
Propanediol solvent, moisturizer/​humectant
Dicaprylyl Carbonate emollient
Caprylic/Capric Triglyceride emollient
Cetearyl Alcohol emollient, viscosity controlling, emulsifying, surfactant/​cleansing 1, 2
Panthenol soothing, moisturizer/​humectant 0, 0 goodie
Lactobacillus Ferment Lysate
Camellia Japonica Seed Oil emollient
Mangifera Indica (Mango) Seed Butter emollient goodie
Niacinamide cell-communicating ingredient, skin brightening, anti-acne, moisturizer/​humectant superstar
Octyldodecyl Myristate emollient
Polysorbate 60 emulsifying, surfactant/​cleansing
1,2-Hexanediol solvent
Cetearyl Glucoside emulsifying, surfactant/​cleansing
Dimethicone emollient 0, 1
Polyglyceryl-3 Methylglucose Distearate emulsifying
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Helianthus Annuus (Sunflower) Seed Oil emollient 0, 0 goodie
Olea Europaea (Olive) Fruit Oil antioxidant, emollient, perfuming 0, 0-2 goodie
Ammonium Acryloyldimethyltaurate viscosity controlling
Hydroxyethyl Urea moisturizer/​humectant goodie
Cetyl Palmitate emollient 0, 0
Sorbitan Olivate emulsifying goodie
Sorbitan Palmitate emulsifying
Hydroxyacetophenone antioxidant
Acrylates/C10-30 Alkyl Acrylate Crosspolymer viscosity controlling
Caprylyl Glycol moisturizer/​humectant, emollient
Argania Spinosa Kernel Oil antioxidant, emollient goodie
Allantoin soothing 0, 0 goodie
Tromethamine buffering
Fragrance(Parfum) perfuming icky
Dipotassium Glycyrrhizate soothing, moisturizer/​humectant goodie
Acetyl Glucosamine skin-identical ingredient, skin brightening goodie
Adenosine cell-communicating ingredient goodie
Lactic Acid exfoliant, moisturizer/​humectant, buffering superstar
Hydrolyzed Hibiscus Esculentus Extract
Moringa Pterygosperma Seed Extract
Lupinus Albus Seed Extract
Ethylhexylglycerin preservative
Sodium Benzoate preservative
Sodium Chloride viscosity controlling
Brassica Campestris (Rapeseed) Seed Oil
Candida Bombicola/Glucose/Methyl Rapeseedate Ferment antimicrobial/​antibacterial, surfactant/​cleansing
Maltodextrin
Raspberry Seed Oil/Tocopheryl Succinate Aminopropanediol Esters moisturizer/​humectant goodie
Bacillus Ferment
Dextrin viscosity controlling, moisturizer/​humectant
Hydrolyzed Vegetable Protein
Lactobacillus Ferment soothing, preservative goodie
Butylene Glycol moisturizer/​humectant, solvent, viscosity controlling 0, 1
Carbomer viscosity controlling 0, 1
Palmitoyl Tripeptide-5 cell-communicating ingredient goodie
Polysorbate 20 emulsifying, surfactant/​cleansing 0, 0
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate cell-communicating ingredient goodie
Tocopherol antioxidant 0-3, 0-3 goodie
Magnesium Chloride viscosity controlling
Palmitoyl Tripeptide-1 cell-communicating ingredient goodie
Palmitoyl Tetrapeptide-7 cell-communicating ingredient goodie

First Lab Probiotic Cream
Ingredients explained

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

Also-called: Zemea | What-it-does: solvent, moisturizer/humectant

Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved. 

It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. 

What-it-does: emollient

A clear, colorless, almost odorless oil that spreads nicely and easily and gives a velvet dry skin feel. It is good friends with sunscreen agents and helps to solubilize them. Also, it makes sunscreens feel lighter and spread easier. 

What-it-does: emollient

A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular. 

What-it-does: emollient, viscosity controlling, emulsifying, emulsion stabilising, surfactant/cleansing | Irritancy: 1 | Comedogenicity: 2

An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.  

It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols.  Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.

Panthenol - goodie
Also-called: Pro-Vitamin B5 | What-it-does: soothing, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid). 

Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier. 

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Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.

Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation. 

If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.

As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily. 

We don't have description for this ingredient yet.

Also-called: Camellia Oil | What-it-does: emollient

We don't have description for this ingredient yet.

Also-called: Mango Seed Oil, Mango Seed Butter;Mangifera Indica Seed Oil | What-it-does: emollient

The soft solid, off-white to ivory butter or oil coming from the kernel (the seed inside of the seed) of the Mango. Similar to many other plant oils, it's a great moisturizing and nourishing emollient oil. It has medium spreadability and gives skin a creamy-dry feel. 

It's loaded with a bunch of good-for-the-skin stuff: it contains almost all of the essential amino acids, has several antioxidant phenolic compounds (including famous antioxidant ferulic acid) and is a rich source of nourishing fatty acids (like stearic and oleic acid).

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All in all, a skin goodie especially for dry skin types. 

Niacinamide - superstar
Also-called: vitamin B3, nicotinamide | What-it-does: cell-communicating ingredient, skin brightening, anti-acne, moisturizer/humectant
  • A multi-functional skincare superstar with several proven benefits for the skin
  • Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
  • Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
  • Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
  • Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
Read all the geeky details about Niacinamide here >>

What-it-does: emollient

We don't have description for this ingredient yet.

A common little helper ingredient that helps water and oil to mix together, aka emulsifier.

What-it-does: solvent

A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives

A sugar based emulsifier that's especially great for low viscosity lotions or even sprays. It's effective in small amounts, only 1-1.5% is needed to form an emulsion. The resulting cream or lotion has great cosmetic properties with good spreadability and an enhanced soft skin feel. 

What-it-does: emollient | Irritancy: 0 | Comedogenicity: 1

Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.

As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity. 

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As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types). 

What-it-does: emulsifying

A vegetable-based emulsifier that helps the oily and watery parts of the formula to mix nicely together. It is compatible with a bunch of cosmetic oils as well as active ingredients and its specialty is creating emulsions with super high heat and freeze stability (from -25 °C and +50 °C).

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot)
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

Also-called: Sunflower Oil | What-it-does: emollient | Irritancy: 0 | Comedogenicity: 0

Sunflower does not need a big intro as you probably use it in the kitchen as cooking oil, or you munch on the seeds as a healthy snack or you adore its big, beautiful yellow flower during the summer - or you do all of these and probably even more. And by even more  we mean putting it all over your face as sunflower oil is one of the most commonly used plant oils in skincare.

It’s a real oldie: expressed directly from the seeds, the oil is used not for hundreds but thousands of years. According to The National Sunflower Association, there is evidence that both the plant and its oil were used by American Indians in the area of Arizona and New Mexico about 3000 BC. Do the math: it's more than 5000 years – definitely an oldie.

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Our intro did get pretty big after all (sorry for that), so let's get to the point finally: sunflower oil - similar to other plant oils - is a great emollient that makes the skin smooth and nice and helps to keep it hydrated. It also protects the surface of the skin and enhances the damaged or irritated skin barrier. Leslie Bauman notes in Cosmetic Dermatology that one application of sunflower oil significantly speeds up the recovery of the skin barrier within an hour and sustains the results 5 hours after using it.

It's also loaded with fatty acids (mostly linoleic (50-74%)  and oleic (14-35%)). The unrefined version (be sure to use that on your skin!) is especially high in linoleic acid that is great even for acne-prone skin. Its comedogen index is 0, meaning that it's pretty much an all skin-type oil

Truth be told, there are many great plant oils and sunflower oil is definitely one of them.

Also-called: Olive Fruit Oil | What-it-does: antioxidant, emollient, perfuming | Irritancy: 0 | Comedogenicity: 0-2

You probably know olive oil from the kitchen as a great and healthy option for salad dressing but it's also a great and healthy option to moisturize and nourish the skin, especially if it's on the dry side. 

Similar to other emollient plant oils, it's loaded with nourishing fatty acids: oleic is the main component (55-83%), and also contains linoleic (3.5-20%) and palmitic acids (7-20%). It also contains antioxidant polyphenols, tocopherols (types of vitamin E) and carotenoids and it's one of the best plant sources of skin-identical emollient, Squalene

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Overall, a great option for dry skin but less so for acne-prone or damaged skin.

Also-called: Aristoflex AVC;Ammonium Acryloyldimethyltaurate/VP Copolymer | What-it-does: viscosity controlling

A kind of polymer (big molecule from repeated subunits) that helps to create beautiful gel-like textures. It's also a texturizer and thickener for oil-in-water emulsions. It gives products a good skin feel and does not make the formula tacky or sticky. 

It works over a wide pH range and is used between 0.5-1.2%.

What-it-does: moisturizer/humectant

A derivative of Urea, that works as a strong moisturizer and humectant meaning that it helps the skin to cling onto water and thus to make it hydrated and elastic.

According to manufacturer's data,  Hydroxyethyl Urea has a similar moisturizing ability to glycerin (measured at 5%), but it feels nicer on the skin as it is non-sticky and non-tacky and gives a lubricous and moist feeling to the skin.

What-it-does: emollient | Irritancy: 0 | Comedogenicity: 0

A white, waxy emollient that gives "body" to skincare formulas. Comes from coconut or palm kernel oil. 

Also-called: Part of Olivem 1000 | What-it-does: emulsifying

An ester coming from sorbitol and the fatty acids of olive oil. It is part of the popular emulsifier trade named Olivem 1000 that is well-known for generating biomimetic liquid crystal structures. We have more info on Olivem 1000 at Cetearyl Olivate >>

What-it-does: emulsifying

A creamy solid that helps water and oil to mix, aka emulsifier. Its solid, wax-like nature is useful for oil-based formulas where some rigidity is needed.

What-it-does: antioxidant

A handy multifunctional ingredient that works as a preservative booster, as well as an antioxidant and soothing agent

Though its long name does not reveal it, this polymer molecule (big molecule from repeated subunits or monomers) is a relative to the super common, water-loving thickener, Carbomer. Both of them are big molecules that contain acrylic acid units, but Acrylates/C10-30 Alkyl Acrylate Crosspolymer also contains some other monomers that are hydrophobic, i.e. water-hating. 

This means that our molecule is part water- and part oil-loving, so it not only works as a thickener but also as an emulsion stabilizer. It is very common in gel-type formulas that also contain an oil-phase as well as in cleansers as it also works with most cleansing agents (unlike a lot of other thickeners). 

It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol

The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.

Also-called: Argan Oil | What-it-does: antioxidant, emollient

When it comes to cosmetic oils and hype, argan oil is for sure leading the way. Dubbed as the "liquid gold of Morocco", we have to admit we have some trouble determining why this oil enjoys such a special miracle status. Not that it's not good, it is good, even great but reading the research about argan and a bunch of other plant oils we just do not see the big, unique differentiating factor (though that might be our fault not reading enough, obvs.)

So, argan oil comes from the kernel of the argan fruit that comes from the argan tree that grows only in Morocco. The tree is slow growing and getting the oil is a hard job. The traditional process is that the ripe argan fruits fall from the tree, then goats eat them up and poop out the seeds. The seeds are collected and smashed with a stone to get the kernels inside. This part is the hard one as the seeds have extremely hard shells. Once the kernels are obtained, the oil is pressed out from them (the kernels contain about 50% oil).

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As for skincare, argan oil is loaded with lots of skin goodies (but so are many other plant oils): it contains 80% nourishing and moisturizing unsaturated fatty acids, mainly oleic (38-50%), linoleic (28-38%) and palmitic (10-18%). It also contains a relatively large amount of antioxidant vitamin E (600-900 mg/kg, about twice as much as olive), small amounts of antioxidant phenols (including caffeic acid, ferulic acid, and epicatechin), as well as some rare sterols with soothing and anti-inflammatory properties. 

Thanks to all the above goodness in argan oil, it can greatly nourish and moisturize the skin and hair. It's also claimed to be able to neutralize collagen-damaging free radicals, help reduce scars, and revitalize and improve skin elasticity. You can even read that argan might help acne-prone skin, but being a high oleic oil, we would be careful with that

All in all, argan oil is a real goodie but we do not fully understand the special miracle status it enjoys.

Allantoin - goodie
What-it-does: soothing | Irritancy: 0 | Comedogenicity: 0

Super common soothing ingredient. It can be found naturally in the roots & leaves of the comfrey plant, but more often than not what's in the cosmetic products is produced synthetically. 

It's not only soothing but it' also skin-softening and protecting and can promote wound healing.

What-it-does: buffering

It's a little helper ingredient that helps to set the pH of the products to be right. It has an alkaline pH and can neutralize acidic ingredients.

Also-called: Fragrance, Parfum;Parfum/Fragrance | What-it-does: perfuming

Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!). 

If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.  

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Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!). 

Also-called: Licorice | What-it-does: soothing, moisturizer/humectant

The salt form of one of the main anti-inflammatory ingredients in the licorice plant, monoammonium glycyrrhizinate. It’s a yellowish powder with a nice sweet smell. 

It’s used mainly for its soothing and anti-inflammatory properties, but according to manufacturer info, it’s also sebum regulating so it's a perfect ingredient for problem skin products. 

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Read more about licorice and why it's a skincare superstar here. 

An amino acid sugar that can be found in the skin and does there good and important things. One of them is that it's a precursor for the biosynthesis of superstar moisturizer, hyaluronic acid. So acetyl glucosamine itself is also an important skin-identical ingredient and natural moisturizing factor.

But that is not all, acetyl glucosamine has two other great properties proved by double-blind clinical trials. First, it's a promising ingredient against wrinkles:  2% can improve wrinkles, particularly in the eye area.

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Second, the same amount can also fade - always stubborn - brown spots. (Do not expect magic, though - the photos from the study show the difference after 8 weeks of daily use. The difference is visible, but not that big. It's always good to have realistic expectations. :))  Combined with skincare superstar niacinamide the duo is synergistic and is more effective at improving hyperpigmentation, so if you are after the skin-lightening benefit look out for products that contain both. 

Adenosine - goodie

Adenosine is an important little compound in our body that has a vital cell-signalling role. Research on smearing it on our face is also promising and shows so far a couple of things:

  • It can help with wound healing
  • It’s a good anti-inflammatory agent
  • It might even help with skin’s own collagen production and improve skin firmness and elasticity
  • It helps with barrier repair and protection
  • It might be even useful for the hair helping with hair thickness and hair growth
Lactic Acid - superstar
  • It’s the second most researched AHA after glycolic acid
  • It gently lifts off dead skin cells to reveal newer, fresher, smoother skin
  • It also has amazing skin hydrating properties
  • In higher concentration (10% and up) it improves skin firmness, thickness and wrinkles
  • Choose a product where you know the concentration and pH value because these two greatly influence effectiveness
  • Don’t forget to use your sunscreen (in any case but especially so next to an AHA product)
Read all the geeky details about Lactic Acid here >>

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

What-it-does: preservative, deodorant

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient

What-it-does: preservative

A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi. 

It’s pH dependent and works best at acidic pH levels (3-5). It’s not strong enough to be used in itself so it’s always combined with something else, often with potassium sorbate.

Also-called: Salt | What-it-does: viscosity controlling

Sodium chloride is the fancy name of salt. Normal, everyday table salt

If (similar to us) you are in the weird habit of reading the label on your shower gel while taking a shower, you might have noticed that sodium chloride is almost always on the ingredient list. The reason for this is that salt acts as a fantastic thickener in cleansing formulas created with ionic cleansing agents (aka surfactants) such as Sodium Laureth Sulfate. A couple of percents (typically 1-3%) turns a runny surfactant solution into a nice gel texture.

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If you are into chemistry (if not, we understand, just skip this paragraph), the reason is that electrolytes (you know, the Na+ and Cl- ions) screen the electrostatic repulsion between the head groups of ionic surfactants and thus support the formation of long shaped micelles (instead of spherical ones) that entangle like spaghetti, and viola, a gel is formed. However, too much of it causes the phenomenon called "salting out", and the surfactant solution goes runny again. 

Other than that, salt also works as an emulsion stabilizer in water-in-oil emulsions, that is when water droplets are dispersed in the outer oil (or silicone) phase. And last but not least, when salt is right at the first spot of the ingredient list (and is not dissolved), the product is usually a body scrub where salt is the physical exfoliating agent

Also-called: Rapeseed Oil

We don't have description for this ingredient yet.

It's a little helper ingredient coming from corn, rice or potato starch that can help to keep skin mat (absorbent), to stabilise emulsions, and to keep the product together (binding). 

Also-called: Vitaskin E | What-it-does: moisturizer/humectant

This long-named thing comes from the enzymatic biocatalysis of Raspberry Seed Oil and a Vitamin E derivative and is claimed by its manufacturer to be able to repair injured skin and restore a healthy barrier function (so that the skin is healthy and hydrated again). 

The manufacturer did some in-vivo (made on real people) studies to show that 1% Vitaskin-E cream did indeed decrease Trans-Epidermal-Water-Loss and reduced cracks and scales on dry lips better than placebo.

We don't have description for this ingredient yet.

A little helper ingredient that can be a thickener, a humectant, a foam booster, an adhesion promoter and a filler. It's a blend of polysaccharides that helps to moisturize and soften the skin. 

We don't have description for this ingredient yet.

What-it-does: soothing, preservative

Lactobacillus ferment is an interesting probiotic ingredient with some promising properties. 

First, according to a 2009 Estee Lauder patent, it’s a DNA repair enzyme and it can help to protect the skin against environmental aggressors.

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Second, still according to Estee Lauder research but now from 2012 the ingredient has anti-microbial and anti-inflammatory properties and holds promise in the treatment of acne and rosacea. For the former one 5% was needed to show effectiveness, but for reducing skin sensitivity already 1% showed results. 

The anti-acne effect is confirmed also by US manufacturer, Barnet, that says that Lactobacillus ferment is helpful in killing harmful bacteria and creating a healthy balanced microflora. Compared to well-known anti-acne and anti-inflammatory salicylic acid the probiotic worked faster at reducing the size and redness of acne lesions. 

It also goes by the trade name Leucidal Liquid SF and can serve in the formula as a natural preservative. 

Bottom line: It’s not the most proven ingredient (yet) but definitely a very promising one especially if you have sensitive skin, acne or rosacea.  

What-it-does: moisturizer/humectant, solvent, viscosity controlling | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

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It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive. 

What-it-does: viscosity controlling, emulsion stabilising | Irritancy: 0 | Comedogenicity: 1

A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula.  It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.

Also-called: Syn-Coll | What-it-does: cell-communicating ingredient

A tripeptide (three amino acids attached to each other: Lys-Val-Lys) that's claimed to protect and boost collagen and improve skin texture.

The manufacturer did an in-vivo (made on real people) study with 45 volunteers and found that used twice daily for 84 days 1% and 2.5% Syn-Coll reduces the appearance of wrinkles by 7 and 12% respectively. In another study (also by the manufacturer) with 33 female Chinese volunteers, 77% of the participants felt that Syn-Coll visibly improved the firmness and elasticity of the skin after 4 weeks. What's more, 60% of the participants also noticed a reduction in the look of the pore size also after 4 weeks of treatment. 

What-it-does: emulsifying, surfactant/cleansing | Irritancy: 0 | Comedogenicity: 0

It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 

Also-called: SYN-HYCAN | What-it-does: cell-communicating ingredient

A small, three amino acid synthetic tripeptide with a molecular weight smaller than 500 Da (500 Da is often referred to as the limit for proper skin penetration). 

The manufacturer claims that it can boost the synthesis of hyaluronic acid in the skin (up to 300% based on in-vitro tests) that is important for proper skin hydration and plumpness. It can also improve collagen fiber quality by increasing some structural skin elements (so-called proteoglycans), like decorin and lumican.

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The peptide is suggested for firming and remodelling treatments, as well as against skin sagging. It's also marketed as a "needle-free hyaluronan booster".

Tocopherol - goodie
Also-called: Vitamin E | What-it-does: antioxidant | Irritancy: 0-3 | Comedogenicity: 0-3
  • Primary fat-soluble antioxidant in our skin
  • Significant photoprotection against UVB rays
  • Vit C + Vit E work in synergy and provide great photoprotection
  • Has emollient properties
  • Easy to formulate, stable and relatively inexpensive
Read all the geeky details about Tocopherol here >>

What-it-does: viscosity controlling

A kind of salt that's used as a thickener in cosmetic products. 

Also-called: Part of Matrixyl 3000, Pal-GHK, Formerly also Palmitoyl Oligopeptide | What-it-does: cell-communicating ingredient

A really famous peptide that is part of Matrixyl 3000, the most sold peptide complex in the word. Before we go and find out what the big deal with Matrixyl 3000 is, let's just focus on Palmitoyl Tripeptide-1 itself for a bit.

It's a small three amino acid (they are the building blocks of all proteins) peptide with the amino sequence of glycine-histidine-lysine, or GHK. GHK is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration. 

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The GHK part is the important one as it's a type I collagen fragment. When collagen naturally breaks down in the skin, the resulting peptide fragments signal to the skin that it should get to work and create some nice, new collagen. Adding in collagen fragment peptides, like GHK, might trick the skin into thinking that collagen has broken down and it's time to create some more.

Therefore, Palmitoyl Tripeptide-1 is believed to be able to stimulate collagen production in the skin, and more collagen means fewer wrinkles and younger looking skin. 

In Matrixyl 3000, Palmitoyl Tripeptide-1 is coupled with Palmitoyl Tetrapeptide-7  and the duo works in synergy to reduce wrinkles and give younger looking skin. According to the manufacturer's in-vivo (made on real people) test, applying 3% Matrixyl 3000 twice a day for 2 months resulted in all of the following things:

  • 39.4% reduction in surface occupied by deep wrinkles
  • 32.9% reduction in main wrinkle density
  • 19.9% reduction in main wrinkle average depth
  • 16% improvement in roughness
  • 16.2% in lifting effect
  • 5.5% improvement in elasticity
  • 15.5% improvement in skin tone

Manufacturer results, of course, always have to be taken with a pinch of salt, but if you like peptides, the Matryxil 3000 duo is one of the best-proven and most well-known ones and it's something that is worth trying.

Also-called: Part of Matrixyl 3000, Pal-GQPR, Previously Palmitoyl Tetrapeptide-3 | What-it-does: cell-communicating ingredient

A four amino acid peptide with the amino sequence of glycine-glutamine-proline-arginine. It is attached to palmitic acid (a fatty acid)  to increase oil solubility and skin penetration. 

It works by reducing the production of the signal moleculeinteleukin-6 (IL-6) which promotes inflammation in the skin and less inflammation means slower degradation of important things (like collagen) that results in younger looking skin for a longer time. 

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It works in synergy with its pal, Palmitoyl Tripeptide-1 in the famous Matrixyl 3000 complex. You can read some more about the famous duo here.

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