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Dr.ci labo Super White 377Vc

Super White 377Vc

Increased levels of melanin are caused by high levels Tyrosinase activity. Super White 377VC is formulated to especially obstruct the Tyrosinase activity in the skin, making it one of the most efficient whitening treatments available over the counter.
Uploaded by: cindyq on

Ingredients overview

Highlights

#alcohol-free #fragrance & essentialoil-free
Alcohol Free
Fragrance and Essential Oil Free

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Other Ingredients

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Ingredient name what-it-does irr., com. ID-Rating
Water solvent
Neopentyl Glycol Dicaprate emollient
Pentaerythrityl Tetraethylhexanoate emollient, viscosity controlling
Butylene Glycol moisturizer/​humectant, solvent, viscosity controlling 0, 1
Dipropylene Glycol solvent, perfuming, viscosity controlling
Pentylene Glycol solvent, moisturizer/​humectant
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Arachidyl Alcohol emollient, viscosity controlling
Squalane skin-identical ingredient, emollient 0, 1 goodie
Butyrospermum Parkii (Shea) Butter emollient, viscosity controlling goodie
Beeswax emollient, viscosity controlling, emulsifying, perfuming 0, 0-2
Dimethicone emollient 0, 1
Glyceryl Stearate SE emulsifying 2, 3
Behenyl Alcohol emollient, viscosity controlling
Phenylethyl Resorcinol antioxidant, skin brightening goodie
Ammonium Acryloyldimethyltaurate/VP Copolymer viscosity controlling
Arachidyl Glucoside emulsifying, surfactant/​cleansing
Phenoxyethanol preservative
Trisodium Ascorbyl Palmitate Phosphate antioxidant
Inulin Lauryl Carbamate surfactant/​cleansing, emulsifying
Tocopherol antioxidant 0-3, 0-3 goodie
Stearyl Glycyrrhetinate soothing
Cyclodextrin chelating
Xanthan Gum viscosity controlling, emulsifying, surfactant/​cleansing
Caramel colorant
Ethylhexylglycerin preservative
Ascorbic Acid antioxidant, skin brightening, buffering superstar
Larix Sibirica Wood Extract antimicrobial/​antibacterial, antioxidant
Pinus Pinaster Bark Extract antioxidant goodie
Hydrolyzed Hyaluronic Acid moisturizer/​humectant goodie
Glucosyl Hesperidin moisturizer/​humectant
Cellulose Gum viscosity controlling 0, 0
Persea Gratissima (Avocado) Oil antioxidant, emollient 0, 0-3 goodie
Rosa Canina Fruit Oil emollient
Prunus Armeniaca (Apricot) Kernel Oil emollient 0, 1-2 goodie
PVP viscosity controlling 0, 0
Lecithin emollient, emulsifying goodie
Sodium Tocopheryl Phosphate antioxidant, emulsifying, surfactant/​cleansing, viscosity controlling
Resveratrol antioxidant goodie
Sodium Citrate chelating, buffering
Silica viscosity controlling
Glycine Soja (Soybean) Germ Extract emollient
Hydrolyzed Elastin moisturizer/​humectant, emollient
Prunus Mume Fruit Extract moisturizer/​humectant
Chrysanthellum Indicum Extract
Scutellaria Baicalensis Root Extract soothing, antioxidant, antimicrobial/​antibacterial, moisturizer/​humectant goodie
Centella Asiatica Extract soothing, antioxidant, moisturizer/​humectant, surfactant/​cleansing goodie
Rubus Ellipticus Root Extract moisturizer/​humectant
Averrhoa Carambola Leaf Extract moisturizer/​humectant
Passiflora Edulis Fruit Extract
Hydrolyzed Collagen emollient, moisturizer/​humectant goodie
Soluble Proteoglycan
Panthenol soothing, moisturizer/​humectant 0, 0 goodie
Rosa Hybrid Flower Extract
Retinyl Palmitate cell-communicating ingredient 1-3, 1-3
Actinidia Polygama Fruit Extract
Aloe Barbadensis Leaf Extract soothing, emollient, moisturizer/​humectant goodie
Zea Mays (Corn) Oil emulsifying, perfuming 0, 0-3
Lepidium Sativum Sprout Extract
Platinum Powder abrasive/​scrub
Natto Gum
Oligopeptide-34
Fullerenes antimicrobial/​antibacterial
Hexanoyl Dipeptide-3 Norleucine Acetate cell-communicating ingredient goodie

Dr.ci labo Super White 377Vc
Ingredients explained

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

What-it-does: emollient

We don't have description for this ingredient yet.

A high-molecular-weight emollient ester that makes your skin nice and smooth. It leaves a non-oily, light, "wet" feel on the skin. 

What-it-does: moisturizer/humectant, solvent, viscosity controlling | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

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It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive. 

A clear, colorless liquid that works as a solvent and viscosity decreasing ingredient. It also has great skin-moisturizing abilities. 

A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent and a broad spectrum antimicrobial. According to manufacturer info, it's also a moisturizer and helps to make the product feel great on the skin. It works synergistically with preservatives and helps to improve water-resistance of sunscreens. 

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot)
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

A fatty alcohol (the non-drying type with a long oil loving chain of 20 carbon atoms) that is used to increase the viscosity of the formula and it also helps the oily and the watery parts to stay nicely mixed together (called emulsion stabilizing). 

Squalane - goodie
What-it-does: skin-identical ingredient, emollient | Irritancy: 0 | Comedogenicity: 1

It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated  (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life. 

It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy.

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Another advantage of squalane is that it is pretty much compatible with all skin types and skin conditions. It is excellent for acne-prone skin and safe to use even if you have fungi-related skin issues, like seborrhea or fungal acne.

The unsaturated (with double bonds) and hence less stable version of Squalane is Squalene, you can read about it here >> 

Also-called: Shea Butter | What-it-does: emollient, viscosity controlling

Unless you live under a rock you must have heard about shea butter. It's probably the most hyped up natural butter in skincare today. It comes from the seeds of African Shea or Karite Trees and used as a magic moisturizer and emollient.

But it's not only a simple emollient, it regenerates and soothes the skin, protects it from external factors (such as UV rays or wind) and is also rich in antioxidants (among others vitamin A, E, F, quercetin and epigallocatechin gallate). If you are looking for rich emollient benefits + more, shea is hard to beat. 

Also-called: Cera Alba | What-it-does: emollient, viscosity controlling, emulsifying, perfuming | Irritancy: 0 | Comedogenicity: 0-2

It's the yellow, solid stuff that you probably know from beeswax candles. It's a natural material produced by honey bees to build their honeycomb.

As for skincare, it's used as an emollient and thickening agent. It's super common in lip balms and lipsticks. 

What-it-does: emollient | Irritancy: 0 | Comedogenicity: 1

Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.

As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity. 

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As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types). 

What-it-does: emulsifying | Irritancy: 2 | Comedogenicity: 3

An oily kind of ingredient that can magically blend with water all by itself. This is called self-emulsifying and SE in its name stands for that.

The difference between "normal" Glyceryl Stearate and this guy is that the SE grade contains a small amount of water-loving soap molecules, such as sodium stearate. This increases Glyceryl Stearate's affinity for water and gives it stronger emulsifying abilities.    

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Other than that, it’s a nice emollient that gives a smooth and soft appearance to the skin.

You can read some more at Glyceryl Stearate >>

A fatty alcohol (the non-drying type with a long oil loving chain of 22 carbon atoms) that is used to increase the viscosity of the formula and it also helps the oily and the watery parts to stay nicely mixed together (called emulsion stabilizing). 

Also-called: SymWhite | What-it-does: antioxidant, skin brightening

A skin-lightening and antioxidant active ingredient derived from a molecule that exists naturally in Pine tree. According to the clinical results of the manufacturer, 0.5% of phenylethyl resorcinol is more effective than 1% of well-known skin-lightener kojic acid. 

Though the results from the manufacturer sound quite promising, a skin-lightening study from 2013 involving phenylethyl resorcinol shows quite moderate results. In the 80 participants, 12-week study, phenylethyl resorcinol was combined with three other actives (disodium glycerophosphate, L-leucine, and undecylenoyl phenylalanine) and only 57% of the participants showed at least a moderate response and 17% did not improve at all.

Also-called: Aristoflex AVC | What-it-does: viscosity controlling

A kind of polymer (big molecule from repeated subunits) that helps to create beautiful gel-like textures. It's also a texturizer and thickener for oil-in-water emulsions. It gives products a good skin feel and does not make the formula tacky or sticky. 

It works over a wide pH range and is used between 0.5-1.2%.

An ingredient that is created from the attachment of the water-loving sugar molecule, glucose, and an oil-loving 20 carbon long fatty chain. This makes it a partly water- and partly oil-soluble material, meaning it functions as an emulsifier helping oil and water to mix.  

Most often, it comes to the formula coupled with two fatty alcohol friends, Arachidyl and Behenyl alcohol, to make up an emulsifier trio trade named Montanov 202. As described by its manufacturer, the main thing of Montanonv 202 is that it gives creams a unique evanescent and light feel with a matt finish. It also leaves the skin soft, but not oily, is hypoallergenic and non-comedogenic making it perfect for both oily and sensitive skin formulas. 

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

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Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10). 

It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.

What-it-does: antioxidant

We don't have description for this ingredient yet.

polymeric (big molecule from repeated subunits) emulsifier that comes from Inulin, a naturally occurring polysaccharide found in the roots and rhizomes of several plants. The emulsifier is obtained by adding oil-loving chains onto inulin. The resulting copolymer can emulsify high amounts of oil and can stabilize oil droplets or non-water soluble particles so that they do not clump together in the formula. 

Tocopherol - goodie
Also-called: Vitamin E | What-it-does: antioxidant | Irritancy: 0-3 | Comedogenicity: 0-3
  • Primary fat-soluble antioxidant in our skin
  • Significant photoprotection against UVB rays
  • Vit C + Vit E work in synergy and provide great photoprotection
  • Has emollient properties
  • Easy to formulate, stable and relatively inexpensive
Read all the geeky details about Tocopherol here >>

What-it-does: soothing

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range. 

Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415). 

What-it-does: colorant

The caramel in cosmetics is pretty much the same one that you know from the kitchen. It is derived by controlled heat treatment of food-grade carbohydrates (sugars) and works as a brown colorant

What-it-does: preservative, deodorant

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient

Ascorbic Acid - superstar
Also-called: Vitamin C, L-ascorbic acid | What-it-does: antioxidant, skin brightening, buffering
  • Works best between a concentration of 5-20%
  • Boosts the skin’s own collagen production
  • Fades pigmentation and brown spots
  • If used under sunscreen it boosts its UV protection
  • Extremely unstable and oxidizes very easily in presence of light or air
  • Stable in solutions with water only if pH is less than 3.5 or in waterless formulations
  • Vit E + C work in synergy and provide superb photoprotection
  • Ferulic acid doubles the photoprotection effect of Vit C+E and helps to stabilize Vit C
  • Potent Vit. C serums might cause a slight tingling on sensitive skin
Read all the geeky details about Ascorbic Acid here >>

We don't have description for this ingredient yet.

Also-called: Pycnogenol | What-it-does: antioxidant

A natural plant extract coming from the bark of the maritime pine that grows along the coast of southwest France. The extract contains potent antioxidant molecules, mainly procyanidins and phenolic acids.  Horphag Research trademarked the name 'Pycnogenol', which refers to a standardized, high-active content version of the pine bark extract. 

Pycnogenol is a very well researched ingredient with more than 370 published studies and review articles. Most of these are in-vitro (made in the lab, not on real people) or analyse Pycnogenol when taken orally. It's clear from them that Pycnogenol has a load of health benefits including antioxidant, anti-inflammatory, and anticarcinogenic magical properties (and a bunch of other things such as improving cognitive function, relieving premenstrual symptoms, or enhancing microcirculation). 

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Regarding Pycnogenol and the skin, we found a study from 2012 that examined its effect on the skin when taken as a supplement. After 12 weeks, Pycnogenol supplements resulted in increased skin hydration and elasticity. The researchers thought this was due to the increased synthesis of extracellular matrix molecules such as hyaluronic acid and perhaps collagen. 

As for topical application, the studies are also promising. A 2003 research paper, conducted on mice, showed that topical Pycnogenol (used at 0.05-0.2%) has the potential to provide photoprotection for humans in a complementary role to sunscreens. Meanwhile, a 2004 study concluded,  "pine bark extract is readily absorbed by human skin and can be used for topical application".

Overall, Pycnogenol, or Pinus Pinaster Bark Extract, as it will be listed on the product label, is a well-researched and potent antioxidant that is a welcome addition to any ingredient list. 

What-it-does: moisturizer/humectant

Hydrolyzed Hyaluronic Acid is a low molecular weight, chemically chopped up version of the naturally big molecule and current IT-moisturizer, Hyaluronic Acid (HA). The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to retain water, making it plump and elastic. As HA is a polymer, the subunits can be repeated many times (as a high-molecular-weight version), or just a few times (as a low-molecular-weight version).

We wrote in detail at HA about how different molecular weight versions do different things both as a component of the skin and as a skincare ingredient, so click here and read about all the details. Hydrolyzed Hyaluronic Acid can also come in different molecular-weight versions with different properties:

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  • 100-300 kDa version: apart from moisturizing, this size might also help the skin to repair itself by increasing its self-defense. It is also claimed to boost the wound healing process and is especially helpful for sensitive skin types (acne, rosacea, inflammation-related skin diseases). 
  • 50k Da version: this is the size that is claimed to be able to absorb into the skin and plump up wrinkles, so it is used mainly as an "anti-aging ingredient" 
  • below 50k, around 10k Da version: there is a Japanese version trade named Hyalo-Oligo that has only a 10k molecular weight and is claimed to penetrate the skin very well, have a unique touch and give deep and long-lasting moisturization. Based on the Evonik-research and the natural role of LMW-HA in the body working as a pro-inflammatory signal molecule, this ultra-low molecular weight version is a controversial ingredient

If you wanna become a real HA-and-the-skin expert, you can read much more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).

What-it-does: moisturizer/humectant

We don't have description for this ingredient yet.

Also-called: Carboxymethyl Cellulose | What-it-does: viscosity controlling, emulsion stabilising | Irritancy: 0 | Comedogenicity: 0

A cellulose (the big molecule found in the cell wall of green plants) derivative that is used as an emulsion stabilizer and thickener

Also-called: Avocado Oil, Persea Americana Oil | What-it-does: antioxidant, emollient | Irritancy: 0 | Comedogenicity: 0-3

The oil coming from the pulp of one of the most nutritious fruits in the world, the avocado. It's loaded with the nourishing and moisturizing fatty acid, oleic (70%) and contains some others including palmitic (10%) and linoleic acid (8%). It also contains a bunch of minerals and vitamins A, E and D

Avocado oil has extraordinary skin penetration abilities and can nourish different skin layers. It's a very rich, highly moisturizing emollient oil that makes the skin smooth and nourished. Thanks to its vitamin E content it also has some antioxidant properties. As a high-oleic plant oil, it is recommended for dry skin

Also-called: Rosehip Oil | What-it-does: emollient

Though it says fruit oil in its name, the rosehip fruit contains the seeds that contain the oil. So this one is the same as Rosa Canina Seed Oil,  or Rosehip Oil, known for its high omega fatty acid content (linoleic acid - 51%, linolenic acid - 19% and oleic acid - 20%) and skin-regenerative properties

There is a common misconception that rosehip oil contains vitamin C as the fruit itself does, but vitamin C is a water-soluble vitamin hence it is not contained in the oil. The antioxidant and regenerative properties of the oil probably come from the oil-soluble tocopherols (vitamin E) and carotenoids (pro-vitamin A). Read more here

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Also-called: Apricot Kernel Oil | What-it-does: emollient | Irritancy: 0 | Comedogenicity: 1-2

The emollient plant oil coming from the kernel (the seed of the seed) of the delicious apricot fruit. Like other plant oils, it contains antioxidant vitamin E and nourishing fatty acids (mostly oleic acid 54-74%, linoleic acid 12-35%).

It's a nice general purpose emollient, has nourishing and moisturizing properties (as a high oleic oil it's ideal for dry skin types) and is quite easily absorbed into the skin.

Also-called: Poly Vinyl Pyrollidone | What-it-does: viscosity controlling, emulsion stabilising | Irritancy: 0 | Comedogenicity: 0

These three letters stand for Poly Vinyl Pyrollidone, a big molecule created from repeated units of Vinyl Pyrrolidone, aka VP. Its main thing is being an important film former. It was the first synthetic polymer introduced as a hair fixative in the 1950s instead of insect-derived Shellac. 

So PVP likes to attach itself to surfaces such as the hair and the skin and forms a nice, thin, even film there. The film is useful for holding a hairstyle or extending the wear of color cosmetics and sunscreens. The disadvantage of PVP is that the film is a bit brittle and that PVP loves water (hygroscopic) that tends to destroy the film. This is the reason why hair styled with a PVP based product loses its style in high humidity. To fix this problem, there are now several versions of VP containing film formers that are less sensitive to humidity, for example, the molecule called VP/VA Copolymer

Lecithin - goodie
What-it-does: emollient, emulsifying

A very common ingredient that can be found in all cell membranes. In cosmetics it's quite the multi-tasker: it's an emollient and water-binding ingredient but it's also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes

We don't have description for this ingredient yet.

Resveratrol - goodie
What-it-does: antioxidant

If you are looking for a reason why red wine is good for you, good news, you have found it! Resveratrol, aka the "red grape antioxidant" is the thing that's suspected to keep the French from coronary heart disease despite their not so healthy eating habits (such as high saturated fat intake).

So resveratrol, found in the seed and skin of the red grape (and berries), is a pretty well-known and well-studied molecule that has potent antioxidant, anti-inflammatory, and anticarcinogenic abilities. Most of the studies were done examining resveratrol's promising anti-cancer properties, but as for skin care, it shows a potent protective effect against UV-caused oxidative stress as well as promising effects against multiple types of skin cancer including the most severe one, melanoma (as an adjuvant therapy). 

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When it comes to skincare and antioxidants, "the more the merrier", so resveratrol is definitely a nice addition to any skincare routine.

What-it-does: chelating, buffering

A little helper ingredient that is used to adjust the pH of the product. It also helps to keep products stay nice longer by neutralizing the metal ions in the formula (they usually come from water). 

A white powdery thing that's the major component of glass and sand. In cosmetics, it’s often in products that are supposed to keep your skin matte as it has great oil-absorbing abilities. It’s also used as a helper ingredient to thicken up products or suspend insoluble particles. 

What-it-does: emollient

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

What-it-does: moisturizer/humectant

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Also-called: Skullcap Root Extract | What-it-does: soothing, antioxidant, antimicrobial/antibacterial, astringent, moisturizer/humectant

A traditional Chinese herbal medicine loaded with potent antioxidant and anti-inflammatory flavonoids such as baicalin, baicalein, and wogonin.

If that would not be enough, Skullcap Root is also claimed to have antimicrobial and antifungal properties (also against P.acnes and Malassezia furfur) as well as some skin-brightening activity. A multi-functional skin-goodie.

Also-called: Gotu Kola, Tiger Grass | What-it-does: soothing, antioxidant, moisturizer/humectant, surfactant/cleansing

Centella Asiatica - or gotu kola as normal people call it  - has been used in folk medicine for hundreds of years. It’s traditionally used to improve small wounds, burns and scratches and it’s also a well known anti-inflammatory agent for eczema.

Recently science has taken an interest in Gotu Kola as well and it turns out it really has many active compounds with several benefits. Just for hard-core geeks, the main biologically active compounds are pentacyclic triterpenoid saponins called asiaticoside, madecassoside, asiatic and madecassic acid (also called centellosides).

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One of the biological activities of the centellosides is to be able to stimulate GAGs  (glycosaminoglycans - polysaccharides that are part of the liquidy stuff between our skin cells), and especially hyaluronic acid synthesis in our skin. This is probably one of the reasons why Centella Asiatica Extract has nice skin moisturizing properties that was confirmed by a 25 people, four weeks study along with Centella's anti-inflammatory effects.

Madecassoside can also help in burn wound healing through increasing antioxidant activity and enhancing collagen synthesis. Asiaticoside was shown to increase antioxidant levels on rats skin when applied at 0.2%. 

Centella Asiatica also often shows up in products that try to treat cellulite or striae. Of course, it cannot make a miracle but it might have some effect via regulating microcirculation and normalizing the metabolism in the cells of connective tissues. 

Bottom line: Gotu Kola is a great plant ingredient with proven wound healing, anti-inflammatory, and antioxidant properties. Nice to spot on any ingredient list.  

What-it-does: moisturizer/humectant

We don't have description for this ingredient yet.

What-it-does: moisturizer/humectant

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

The chemically chopped up version of the big protein molecule, collagen. It is often derived from fish or bovine sources and works as a nice moisturizer and humectant that helps the skin to hold onto water.  

To understand a bit more what Hydrolyzed Collagen is, you have to know that proteins are large chains of amino acids connected with so called-peptide bonds. These bonds can be broken up when a water molecule is added and the resulting thing is a mix of shorter length amino acids, also called peptides. So Hydrolyzed Collagen is not really collagen, it is rather an undefined and varying mix of largish peptides. Based on a manufacturer's data, the whole, soluble collagen has an average molecular weight of 300 000 Da, while this chopped up mixture has an average MW of 12 000 Da (still pretty big). 

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The main thing of these largish peptides is to act as water-binding agents, and to make the skin nice and smooth (aka emollient). Hydrolyzed Collagen is also often used in cleansers as it can make harsh surfactants milder and in hair conditioners as it improves the flexibility and manageability of hair. 

If you wanna know more about collagen in cosmetics, we have a shiny explanation about soluble collagen here >> 

We don't have description for this ingredient yet.

Panthenol - goodie
Also-called: Pro-Vitamin B5 | What-it-does: soothing, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid). 

Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier. 

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Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.

Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation. 

If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.

As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily. 

We don't have description for this ingredient yet.

Also-called: Form of Retinoids | What-it-does: cell-communicating ingredient | Irritancy: 1-3 | Comedogenicity: 1-3

It's an ester form of vitamin A (retinol + palmitic acid) that belongs to the "retinoid family". The retinoid family is pretty much the royal family of skincare, with the queen being the FDA-approved anti-aging ingredient tretinoin. Retinol is also a very famous member of the family, but it's like Prince William, two steps away from the throne. Retinyl palmitate will be then little Prince George, quite far (3 steps) away from the throne. 

By steps, we mean metabolic steps. Tretinoin, aka retinoic acid, is the active ingredient our skin cells can understand and retinyl palmitate (RP) has to be converted by our metabolic machinery to actually do something. The conversion is a 3 step one and looks like this:

Expand to read more

retinyl palmitate --> retinol -- > retinaldehyde --> all-trans-retinoic acid

As we wrote in our lengthy retinol description the problem is that the conversion is not terribly effective. The evidence that RP is still an effective anti-aging ingredient is not very strong, in fact, it's weak. Dr. Leslie Baumann in her fantastic Cosmetic Dermatology book writes that RP is topically ineffective

What's more, the anti-aging effectiveness is not the only questionable thing about RP. It also exibits questionable behaviour in the presence of UV light and was the center of a debate between the non-profit group, EWG (whose intentions are no doubt good, but its credibility is often questioned by scientists) and a group of scientists and dermatologists lead by Steven Q. Wang, MD,  director of dermatologic surgery at Memorial-Sloan Kettering Cancer Centre. 

Dr. Leslie Baumann wrote a great review of the debate and summarized the research available about retinyl palmitate here.  It seems that there is a study showing RP being photo protective against UVB rays but there is also a study showing RP causing DNA damage and cytotoxicity in association with UVA. 

We think that the truth lies somewhere in the middle, and we agree with Dr. Baumann's conclusion: "sufficient evidence to establish a causal link between RP and skin cancer has not been produced. Nor, I’m afraid, are there any good reasons to recommend the use of RP". We would add especially during the day!

Bottom line: If you wanna get serious about retinoids, RP is not your ingredient (retinol or tretinoin is!). However, if you use a product that you like and it also contains RP, there is no reason to throw it away. If possible use it at night, just to be on the safe side.

We don't have description for this ingredient yet.

Also-called: Aloe Leaf Extract | What-it-does: soothing, emollient, moisturizer/humectant

The extract coming from the juice containing leaves of the Aloe vera plant. It's usually a hydroglycolic extract (though  oil extract for the lipid parts also exists) that has similar moisturizing, emollient and anti-inflammatory properties as the juice itself. We have written some more about aloe here.

Also-called: Corn Oil | What-it-does: emulsifying, perfuming | Irritancy: 0 | Comedogenicity: 0-3

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

What-it-does: abrasive/scrub

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

A new tripeptide (meaning that it contains three building blocks called amino acids) that can do all kinds of good things for the skin, at least according to the ingredient's manufacturer. Its modest trade name is simply "PerfectionPeptide P3" :) and it can supposedly reactivate the natural desquamation process of the skin. Better desquamation means better skin quality with fewer irregularities and imperfections and in general fewer signs of aging. 

It also speeds up cell renewal that results in fresh, glowing skin, it intensely hydrates, refines skin texture and reduces wrinkle depth. Hence the name Perfection Peptide. (Don't forget, these are all claims coming from the manufacturer, so maybe take it with a little grain of salt. :))

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what‑it‑does emollient | viscosity controlling
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irritancy, com. 2, 3
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irritancy, com. 0, 0
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what‑it‑does antioxidant
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what‑it‑does chelating | buffering
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what‑it‑does emollient
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what‑it‑does cell-communicating ingredient
irritancy, com. 1-3, 1-3
An ester form of vitamin A (retinol + palmitic acid) that is pretty much the least effective member of the retinoid family. Its anti-aging effects are quite questionable as well as its behavior in the presence of UVA light. (Use it at night if possible!) [more]
what‑it‑does soothing | emollient | moisturizer/humectant
The extract coming from the juice containing leaves of the Aloe vera plant with moisturizing, emollient and anti-inflammatory properties. [more]
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irritancy, com. 0, 0-3
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