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Perricone MD High Potency Classics Firming Eye Lift

High Potency Classics Firming Eye Lift

Perricone MD High Potency Classics: Firming Eye Lift is a featherweight eye serum designed to firm, lift & tighten skin's appearance over time.
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Ingredient name what-it-does irr., com. ID-Rating
Water/Aqua solvent
Tetrahexyldecyl Ascorbate antioxidant, skin brightening goodie
Cetearyl Alcohol emollient, viscosity controlling, emulsifying, surfactant/​cleansing 1, 2
Polysorbate 60 emulsifying, surfactant/​cleansing
Squalane skin-identical ingredient, emollient 0, 1 goodie
Undecylenoyl Phenylalanine skin brightening goodie
Phosphatidylcholine emulsifying
Isopropyl Palmitate emollient 1, 3-4
Benzyl Alcohol preservative, perfuming, solvent, viscosity controlling
Dimethyl Mea buffering
Camellia Oleifera Leaf Extract antioxidant, soothing goodie
Calophyllum Tacamahaca Seed Oil soothing, emollient goodie
Emblica Officinalis Fruit Extract
Sodium Benzoate preservative
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Resveratrol antioxidant goodie
Pinus Pinaster Bark/Bud Extract antimicrobial/​antibacterial, antioxidant
Elaeis Guineensis (Palm) Oil emollient
Tocotrienols
Magnesium Aspartate
Zinc Gluconate anti-acne, soothing goodie
Disodium EDTA chelating
Ascorbyl Palmitate antioxidant 0, 2 icky
Hydroxydecyl Ubiquinone antioxidant
Hesperidin Methyl Chalcone antioxidant goodie
Steareth-20 emulsifying, surfactant/​cleansing 1, 2
Tocopherol antioxidant 0-3, 0-3 goodie
Copper Gluconate soothing goodie
Sodium Hyaluronate skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Astaxanthin antioxidant goodie
Acetyl Tetrapeptide-5 cell-communicating ingredient, moisturizer/​humectant goodie
Dipeptide-2 cell-communicating ingredient goodie
Palmitoyl Tetrapeptide-7 cell-communicating ingredient goodie

Perricone MD High Potency Classics Firming Eye Lift
Ingredients explained

Also-called: Aqua;Water | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

Also-called: Form of Vitamin C, Ascorbyl Isotetrapalmitate, Ascorbyl Tetraisopalmitate, ATIP | What-it-does: antioxidant, skin brightening

Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of skincare big shot Vitamin C. If you do not know, why Vitamin C is such a big deal in skincare, click here and read all about it. We are massive vitamin C fans and have written about it in excruciating detail.

So now, you know that Vitamin C is great and all, but it's really unstable and gives cosmetics companies many headaches. To solve this problem they came up with vitamin C derivatives, and one of them is Tetrahexyldecyl Ascorbate (let's call it ATIP in short).

What-it-does: emollient, viscosity controlling, emulsifying, emulsion stabilising, surfactant/cleansing | Irritancy: 1 | Comedogenicity: 2

An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.  

It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols.  Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.

A common little helper ingredient that helps water and oil to mix together, aka emulsifier.

Squalane - goodie
What-it-does: skin-identical ingredient, emollient | Irritancy: 0 | Comedogenicity: 1

It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated  (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life. 

It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy.

Also-called: Sepiwhite MSH | What-it-does: skin brightening

If you have pigmentation issues, Undecylenoyl Phenylalanine is something to look at. It is an amino acid (Phenylalanine) derived molecule that is thought to hinder the pigmentation process in a unique way by being a so-called MSH-antagonist

MSH stands for Melanocyte Stimulating Hormone, and as you have probably guessed by its name, it is important in the process of melanogenesis, i.e. the generation of melanin pigments. MSH binds to a receptor on the melanocyte (the skin cell that creates melanin) called Melanocortin 1 Receptor (MC1R), which kicks off a bunch of biological processes that result in the formation of pigment. Our guy, Undecylenoyl Phenylalanine can hinder this binding and thus the whole melanin creation process afterward.  

What-it-does: emulsifying

We don't have description for this ingredient yet.

What-it-does: emollient | Irritancy: 1 | Comedogenicity: 3-4

A clear, colorless emollient ester (oily liquid from isopropyl alcohol + palmitic acid) that makes the skin nice and smooth. It has very good spreading properties and gives a silky touch to the products.

It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It can be naturally found in fruits and teas but can also be made synthetically.

No matter the origin, in small amounts (up to 1%) it’s a nice, gentle preservative. Has to be combined with some other nice preservatives, like potassium sorbate to be broad spectrum enough.  

Also-called: DMAE;Dimethyl MEA | What-it-does: buffering

We don't have description for this ingredient yet.

Also-called: tea oil camellia;Camellia Oleifera Leaf Extract | What-it-does: antioxidant, soothing

Camellia Oleifera is a type of green tea plant that's mostly known for the oil that comes from its seeds. As for the leaves, it has similar properties as the better known and more often used Camellia Sinensis leaves. You can read all the geeky details about green tea  and why it's awesome by clicking here, but in short, it has antioxidants and anti-inflammatory magic properties.

Also-called: Tamanu Oil;Calophyllum Tacamahaca Oil | What-it-does: soothing, emollient

An oil coming from cool places like Tahiti, Bora Bora, and the island of Polynesia. Similar to other more common plant oils, it's loaded with nourishing and moisturizing fatty acids (oleic acid: 40%, linoleic acid: 35%, palmitic acid: 15% and stearic acid: 11%).

Its unique thing is that it contains calophyllic acid that gives the oil extra healing and regenerating effects. A manufacturer even claims that tamanu oil can protect small capillary vessel and is recommended for redness and rosacea-prone skin

We don't have description for this ingredient yet.

What-it-does: preservative

A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi. 

It’s pH dependent and works best at acidic pH levels (3-5). It’s not strong enough to be used in itself so it’s always combined with something else, often with potassium sorbate.

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot)
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

Resveratrol - goodie
What-it-does: antioxidant

If you are looking for a reason why red wine is good for you, good news, you have found it! Resveratrol, aka the "red grape antioxidant" is the thing that's suspected to keep the French from coronary heart disease despite their not so healthy eating habits (such as high saturated fat intake).

So resveratrol, found in the seed and skin of the red grape (and berries), is a pretty well-known and well-studied molecule that has potent antioxidant, anti-inflammatory, and anticarcinogenic abilities. Most of the studies were done examining resveratrol's promising anti-cancer properties, but as for skin care, it shows a potent protective effect against UV-caused oxidative stress as well as promising effects against multiple types of skin cancer including the most severe one, melanoma (as an adjuvant therapy). 

We don't have description for this ingredient yet.

What-it-does: emollient

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

What-it-does: anti-acne, soothing, deodorant

If you are fighting acne and have looked into oral supplements, chances are that zinc gluconate sounds familiar to you. It is a zinc salt that has research proving it to be effective against inflammatory acne, though not quite as effective as the antibiotic minocycline (31.2% vs. 63.4% success rate). However, zinc supplements are easily available, have little-to-no side effects, so supplementing them with a 30mg per day dose can still be a good idea.

As for smearing zinc gluconate all over your face, it is also not a bad idea. Zinc has multiple magic abilities: it is antibacterial (including evil, acne-causing P. acnes) and sebum-regulating (5α-reductase inhibitor), great for acne-prone skin types. It also stimulates antioxidant enzyme systems (mainly superoxide dismutase) and has nice wound healing abilities acting mainly in the first, proliferation phase. So great for skin types in need of healing and soothing.

What-it-does: chelating

Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.

It is typically used in tiny amounts, around 0.1% or less.

Also-called: Form of Vitamin C | What-it-does: antioxidant | Irritancy: 0 | Comedogenicity: 2

A form of skincare superstar, vitamin C. Even though we are massive vitamin C fans,  Ascorbyl Palmitate  (AP) is our least favorite. (Btw, if you do not know what the big deal with vitamin C is then you are missing out. You must go and read our geeky details about it.) 

So, AP is one of the attempts by the cosmetics industry to solve the stability issues with vitamin C while preserving its benefits,  but it seems to fall short on several things.

Also-called: Idebenone | What-it-does: antioxidant

We don't have description for this ingredient yet.

Also-called: Part of Eyeliss | What-it-does: antioxidant

This guy - let's just call it simply HMC - is a so-called flavonoid (flavonoids are natural things found it lots of fruits and vegetables). Hesperidin, in particular, is a flavonone and is found in citrus fruits. The methylation of hesperidin gives HMC, that has well-established blood vessel protecting properties and can be found in drugs that treat problems related to blood vessels.

As for skincare, there is a mouse study showing HMC has very promising abilities in the "treatment of UVB irradiation-induced skin inflammation and oxidative stress", or English translation = it's an antioxidant and anti-inflammatory

What-it-does: emulsifying, surfactant/cleansing | Irritancy: 1 | Comedogenicity: 2

A waxy solid material that helps oil and water to mix together, aka emulsifier. It is derived from the fatty alcohol called stearyl alcohol by ethoxylating it and thus making the molecule more water-soluble.

The end result is a mostly water-loving emulsifier, also called solubilizer that can help to dissolve small amounts of oil-loving ingredients into water-based products. Or it can be combined with more oil-loving emulsifiers (such as its sister, Steareth-2) to create stable emulsions. 

Tocopherol - goodie
Also-called: Vitamin E | What-it-does: antioxidant | Irritancy: 0-3 | Comedogenicity: 0-3
  • Primary fat-soluble antioxidant in our skin
  • Significant photoprotection against UVB rays
  • Vit C + Vit E work in synergy and provide great photoprotection
  • Has emollient properties
  • Easy to formulate, stable and relatively inexpensive
Read all the geeky details about Tocopherol here >>

What-it-does: soothing

A copper salt (copper cation + gluconate anion) probably best known for promoting cellular regeneration and wound healing. It works mainly in the final healing phase that complements nicely with the wound healing abilities of its mineral salt sister, zinc gluconate

Other than that, copper is also involved in several enzyme systems: it is a cofactor for the antioxidant enzyme, superoxide dismutase and also a cofactor for the melanin stimulating enzyme, tyrosinase. This means that copper has some tan activating properties, though we think you should not be into tanning at all, as UV is so bad for the skin

What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It’s the - sodium form - cousin of the famous NMFhyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

Astaxanthin - goodie
What-it-does: antioxidant

An oil-loving, red-orange colored pigment that is becoming more and more well-known as a potent antioxidant.

If being an orange-colored pigment reminds you of beta-carotene from carrots, that is no coincidence: astaxanthin also belongs to the chemical group called carotenoids known for giving yellow, orange, or red color to plants. Our guy comes mostly from microalgae, a well-known and often used source is Haematococcus Pluvialis

Also-called: EYESERYL | What-it-does: cell-communicating ingredient, moisturizer/humectant

A four amino acid peptide that is claimed to improve puffy eye bags via its anti-oedema and anti-glycation effects.

To back this claim up, the manufacturer created an in-vivo study with 20 volunteers using 10% of EYESERYL (that comes down to 0.01% (!) of the pure peptide) and found that by day 15, 70% of the volunteers improved, while 95% of the volunteers improved by the end of the study (60 days). About third of them improved only slightly, third of them showed an ok improvement and third showed a good improvement. They also have pretty convincing before and after photos, so we can tell you that for the lucky ones, the improvement can be real and visible.

Dipeptide-2 - goodie
Also-called: Part of Eyeliss | What-it-does: cell-communicating ingredient

A tiny peptide with only two amino acids (amino acids are the building block of proteins, and peptides are a few amino acids attached together), Valine and Tryptophan. It's part of a 3 actives complex called Eyeliss (with HMC and Palmitoyl Tetrapeptide-7) that's supposed to fight under-eye bags

The manufacturer claims that this dipeptide in Eyeliss can increase lymphatic circulation and the three actives together represent a "global approach to treating puffy eyes". The clinical study of the manufacturer with 20 people and 3% Eyeliss showed improvement after 56 days for 70% of the participants.

Also-called: Part of Matrixyl 3000, Pal-GQPR, Previously Palmitoyl Tetrapeptide-3 | What-it-does: cell-communicating ingredient

A four amino acid peptide with the amino sequence of glycine-glutamine-proline-arginine. It is attached to palmitic acid (a fatty acid)  to increase oil solubility and skin penetration. 

It works by reducing the production of the signal moleculeinterleukin-6 (IL-6) which promotes inflammation in the skin and less inflammation means slower degradation of important things (like collagen) that results in younger looking skin for a longer time. 

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does antioxidant | skin brightening
A stable, oil-soluble form of Vitamin C, that might have (in-vitro results) all the magic abilities of pure vitamin C (antioxidant, collagen booster, skin brightener). [more]
what‑it‑does emollient | viscosity controlling | emulsifying | surfactant/cleansing
irritancy, com. 1, 2
A super common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams. [more]
what‑it‑does emulsifying | surfactant/cleansing
A common little helper ingredient that helps water and oil to mix together, aka emulsifier.
what‑it‑does skin-identical ingredient | emollient
irritancy, com. 0, 1
An emollient and natural moisturizer that can be found also in the sebum (oily stuff our skin produces). It leaves a nice non-greasy, non-heavy feeling on the skin. [more]
what‑it‑does skin brightening
If you have pigmentation issues, Undecylenoyl Phenylalanine is something to look at. It is an amino acid (Phenylalanine) derived molecule that is thought to hinder the pigmentation process in a unique way by being a so-called MSH-antagonist. MSH stands for Melanocyte Stimulating Hormone, and as you have probably guessed by its name, it is  [more]
what‑it‑does emulsifying
what‑it‑does emollient
irritancy, com. 1, 3-4
A clear, colorless emollient ester (oily liquid) that makes the skin nice and smooth. [more]
what‑it‑does preservative | perfuming | solvent | viscosity controlling
It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It can be naturally found in fruits and teas but can also be made synthetically. No matter the origin, in small amounts (up to 1%) it’s a nice, gentle preservative. [more]
what‑it‑does buffering
what‑it‑does antioxidant | soothing
A type of green tea that has antioxidants and anti-inflammatory properties. [more]
what‑it‑does soothing | emollient
Tamanu oil - a nourishing and moisturizing oil rich in fatty acids. Contains calophyllic acid that makes the oil extra healing and regenerating. [more]
what‑it‑does preservative
A preservative that works mainly against fungi. Has to be combined with other preservatives. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
what‑it‑does antioxidant
A pretty well-known antioxidant that can be found in the skin and seeds of grapes, berries, and peanuts. It also has anti-inflammatory and anti-cancer (including skin cancer) magic properties. [more]
what‑it‑does antimicrobial/antibacterial | antioxidant
what‑it‑does emollient
what‑it‑does anti-acne | soothing
A zinc salt known for its soothing and wound healing properties as well as for its anti-acne properties.  [more]
what‑it‑does chelating
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. [more]
what‑it‑does antioxidant
irritancy, com. 0, 2
An oil soluble vitamin C derivative that has mixed data about its effectiveness. [more]
what‑it‑does antioxidant
what‑it‑does antioxidant
This guy - let's just call it simply HMC - is a so-called flavonoid (flavonoids are natural things found it lots of fruits and vegetables). Hesperidin, in particular, is a flavonone and is found in citrus fruits. [more]
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 1, 2
A waxy solid material that helps oil and water to mix together, aka emulsifier. It is derived from the fatty alcohol called stearyl alcohol by ethoxylating it and thus making the molecule more water-soluble.The end result is a mostly water-loving emulsifier, also called solubilizer that can help to dissolve small amounts of oil-loving ingredients into water-based  [more]
what‑it‑does antioxidant
irritancy, com. 0-3, 0-3
Pure Vitamin E. Great antioxidant that gives significant photoprotection against UVB rays. Works in synergy with Vitamin C. [more]
what‑it‑does soothing
A copper salt that is known to promote cellular regeneration and also has some antioxidant and tan-activating properties. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
what‑it‑does antioxidant
An oil-loving, red-orange colored pigment known for being a potent antioxidant. [more]
what‑it‑does cell-communicating ingredient | moisturizer/humectant
A four amino acid peptide that is claimed to improve puffy eye bags via its anti-oedema and anti-glycation effects.To back this claim up, the manufacturer created an in-vivo study with 20 volunteers using 10% of EYESERYL (that comes down to 0.01% (!) of the pure peptide) and found that by day 15, 70% of the volunteers improved, while 95% of the volunteers improved by the end of the study (60 d [more]
what‑it‑does cell-communicating ingredient
A tiny peptide with only two amino acids (amino acids are the building block of proteins, and peptides are a few amino acids attached together), Valine and Tryptophan. [more]
what‑it‑does cell-communicating ingredient
The pal of Palmitoyl Tripeptide-1 in Matrixyl 3000. A four amino acid peptide that works by reducing the production of the signal molecule, inteleukin-6 (IL-6) that promotes inflammation in the skin. [more]