Follow us on our new Insta page »

Superoxide Dismutase

Also-called-like-this: SOD
What-it-does: antioxidant

Official CosIng Information


Superoxide Dismutase - or in short SOD - is the body's smart antioxidant enzyme that protects the cells from highly reactive, cell-damaging superoxide radicals (O2−).

You have probably read the terms "free radicals" and "antioxidants" a thousand times, and you know that free radicals are the evil guys, and antioxidants are the good guys. So superoxide radical is a very common free radical that can cause all kinds of cell damages and superoxide dismutase is an enzyme that catalyzes the conversion of superoxide radicals into molecular oxygen and hydrogen peroxide (btw, this one has to be further converted by other antioxidant enzymes, called catalases).

The extra nice thing about SOD is that it remains intact during the neutralization process and can continue its magic, while non-enzymatic antioxidants (like vitamin E) are used up during neutralization.

The efficacy studies of topical SOD are promising. In-vitro (made in the lab) tests show that SOD is a more effective antioxidant than vitamin E, green tea extract, and MAP. There is also an in-vivo (made on real people) study that measured how SOD can reduce the redness caused by UV rays and it was much more effective than vitamin E (pure or acetate form) and ascorbyl palmitate

All in all, SOD is a really potent antioxidant and slathering it all over yourself is a great way to give the skin a little extra help in protecting itself from all the bad environmental things out there. 

Show me some proof

  • International Journal of Cosmetic Science, Apr 1, 2000, The future of enzymes in cosmetics

Products with Superoxide Dismutase

Le Mieux Pomegranate Massage Cream NIOD Superoxide Dismutase Saccharide Mist (SDSM2) Image Skincare Vital C Hydrating Repair Crème NIOD Ethylated L-Ascorbic Acid 30% Network NOID Ethylated L-Ascorbic Acid 30% Network Le Mieux TGF-B Booster Serum LeMieux Tgf-B Booster Organys Eye Cream Allies of Skin Triple Hyaluronic Antioxidant Hydration Serum Cosmedix Pure Enzymes Cranberry Exfoliating Mask Klur Brilliant Light Stubborn Cosmetics Skin Mercy Antioxidant Face Mist TRUE BOTANICALS Renew Repair Serum Le Mieux Collagen Peptide Serum Allies of Skin Vitamin C 35% Collagen Rebuilding Serum Framesi Color Lover Moisture Rich Conditioner Framesi Color Lover Moisture Rich Masque Le Mieux Stemcell EGF NIOD Survival 0 Natura Siberica Age-Delay Eye Serum TRUE BOTANICALS Clear Cellular Repair Serum Your Best Face (YBF-Skincare) Refresh Eye Cream Zelens Intense Defence Antioxidant Serum Farmec gerovital Fiole Acid Hialuronic Hylamide Glow Booster Le Mieux Collagen Peptide Serum Pestle & Mortar Renew Gel Cleanser Stubborn Cosmetics Face Tickle Dr Dennis Gross C+ Collagen Mist Perfect Skin Set & Refresh MD Formulations Moisture Defense Antioxidant Spray Derma E Ultra Hydrating Alkaline Gel Booster Framesi Color Lover Smooth Shine Shampoo Garden of Wisdom Anti-Aging Multipeptide Serum Image Vital C Hydrating Enzyme Masque Skin Actives Redness Reduction Serum The Chemistry Brand Glow Oil Allies of Skin Mandelic Pigmentation Corrector Night Serum Andalou Naturals Cannacell D.Puff Eye Cream Cosmedix Radiance Age Restorative Serum Framesi Color Lover Volume Boost Shampoo Le Mieux Rx Complex Serum Stubborn Cosmetics Face Smooch Moisturizer (Green Ingredients) Arcona Booster Defense Serum® Dr. Dennis Gross Skincare C + Collagen Brighten & Firm Vitamin C Serum Framesi Color Lover Moisture Rich Shampoo Kristina Holey + Marie Veronique Pure + E.O. Free Oil Cleanser Le Mieux Essence Moisturizer Stubborn Cosmetics Face Smooch Moisturizer (White Ingredients) Arcona Youth Serum™ NCN PRO SKINCARE Ncn Eye Fix