Follow us on our new Insta page »

Zinc Gluconate

What-it-does: anti-acne, soothing, deodorant


If you are fighting acne and have looked into oral supplements, chances are that zinc gluconate sounds familiar to you. It is a zinc salt that has research proving it to be effective against inflammatory acne, though not quite as effective as the antibiotic minocycline (31.2% vs. 63.4% success rate). However, zinc supplements are easily available, have little-to-no side effects, so supplementing them with a 30mg per day dose can still be a good idea.

As for smearing zinc gluconate all over your face, it is also not a bad idea. Zinc has multiple magic abilities: it is antibacterial (including evil, acne-causing P. acnes) and sebum-regulating (5α-reductase inhibitor), great for acne-prone skin types. It also stimulates antioxidant enzyme systems (mainly superoxide dismutase) and has nice wound healing abilities acting mainly in the first, proliferation phase. So great for skin types in need of healing and soothing.

What about the gluconate part? It is there to promote the absorption and bioavailability of zinc and also plays a role in cellular regeneration (involved in the synthesis of ribose sugars, structural components of DNA and RNA).

Show me some proof

  • Dreno, B., et al. "Low doses of zinc gluconate for inflammatory acne." Acta Derm Venereol 69.6 (1989): 541-3.
  • Dreno, Brigitte, et al. "Multicenter randomized comparative double-blind controlled clinical trial of the safety and efficacy of zinc gluconate versus minocycline hydrochloride in the treatment of inflammatory acne vulgaris." Dermatology 203.2 (2001): 135-140.
  • Tenaud, I., et al. "In vitro modulation of keratinocyte wound healing integrins by zinc, copper and manganese." British Journal of Dermatology 140.1 (1999): 26-34.

Products with Zinc Gluconate

Glowderma Sebonac Gel Goodal Heartleaf Calming Mineral Filter Sun Cream Kerastase Fondant Chromatique Conditioner Levinia Serum Recuperador Novexpert Trio-Zinc Mist Seven Rinzu UV Spray 1STLY Skincare Electrolyte Energetic Serum Clear Skin Collective Peptide Restore Calming Cream Eximia Aqua Mat Micelar Kerastase Reflection Masque Chromatique Fine Hair Modum SOS-gel SEPHORA COLLECTION Clarifying Toner With Niacinamide And Zinc Typology Sensitive Skin Serum 5 Mineral Complex APIS Oxy O2 Terapis Oxygenating Gel Mask Acneed Acne Control Lotion BIO VÉGANE Bio Acai Refine Clay Mask Bioderma Sebium Micellar Water Derma-ceutix Hydrating Vitamin Mist Eau Thermale Avène Cleanance MAT Mattifying Toner Emina Ms. Pimple Exfoliating Toner Erha Acne Act Acne Blemish Toner Witch Hazel & Chamomile Erha Acne Act Witch Hazel And Chamomile Acne Blemish Toner Erhair Scalperfect Allantoin & Silk Protein Scalp Soothing Serum Fundamentals Skincare Rejuvinating Masque Keve Niacinamide 10% Serum MATH scientific Active Serum "Anti-acne SOS" MATH scientific Deep Cleansing Gel Wash To Fight Acne And Blemishes ME+ Niacinamide & Zinc Booster Macrolibrarsi Attivi Puri Niacinamide + Zinco Medihealth Edapil Shampoo Oxynergy Power Infuse Toning Mist Salthouse Natural Minerals Anti Pickel Akut Ice Gel Skindinavia The Post-Makeup Recovery Spray Violette_FR Sérum Superlatif Blemish Rescue (breakout Calming Serum) bioearth Zinc + Niacinamide 11% APIS Hyaluronic Water Oxygenating Mist APIS Oxygenating Body Mist With Hyaluronic Acid AcneFree Retinol Blemish Mark Resurfacing Serum Bioderma Sebium Gel Moussant Actif Bioderma Sébium Gel Moussant Actif Bioderma Sébium Sensitive Soothing Anti-Blemish Care Biotherm Biopur Matifying Astringent Lotion Cosmetic Plant Ser Energy Boost Good Skin Derma-ceutix Hyaluronic Anti-oxidant Mask Dermaceutic Oxybiome Cleansing Micellar Water Dermies Clear Me Acne Care Toner Dove Scalp + Hair Therapy Fullness Restore Scalp Serum Erha Acneact Anti Acne Serum Eximia Hyalu- B Concentré GRAVICH Oily Sebum Reducer First Care Toner