Perricone MD Cold Plasma Face Serum Concentrate
Perricone MD

Cold Plasma Face Serum Concentrate

One jar that does it all. A multi-tasking powerhouse, this advanced face serum concentrate promotes the 9 most visible signs of healthy, youthful-looking skin. Targets and dramatically improves loss of [more] [more] radiance, uneven texture, uneven tone, discoloration, redness, enlarged pores, fine lines, wrinkles and loss of firmness [less]
Uploaded by: cassidygxoxo on 29/07/2018

Ingredients overview

Water/Aqua/Eau
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
,
Glycerin
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
,
Isopropyl Palmitate
what‑it‑does emollient
irritancy, com. 1 4
A clear, colorless emollient ester (oily liquid) that makes the skin nice and smooth. [more]
,
Cetearyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling | surfactant/cleansing
irritancy, com. 1 2
A common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products. [more]
,
Glyceryl Stearate
what‑it‑does emollient | emulsifying
Waxy, white, solid stuff that helps water and oil to mix together and leaves the skin feeling soft and smooth. [more]
,
Peg-100 Stearate
what‑it‑does surfactant/cleansing | emulsifying
irritancy, com. 0 1
A commonly used water-soluble surfactant and emulsifier. [more]
,
Butylene Glycol
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
,
Phosphatidylcholine
what‑it‑does emulsifying
,
Tetrahexyldecyl Ascorbate
what‑it‑does antioxidant | skin brightening
A stable, oil-soluble form of Vitamin C, that might have (in-vitro results) all the magic abilities of pure vitamin C (antioxidant, collagen booster, skin brightener). [more]
, [more]
Dimethyl Mea
what‑it‑does buffering
,
Acetyl Hexapeptide-8
what‑it‑does cell-communicating ingredient | moisturizer/humectant
Argireline - famous peptide that's often referred to as "Botox in a jar". In reality, it's nowhere near that powerful, but it can smooth wrinkles to some extent by preventing facial muscles from contracting. [more]
,
Palmitoyl Tripeptide-1
what‑it‑does cell-communicating ingredient
A three amino acid peptide that is part of famous peptide duo, Matrixyl 3000. It's a type I collagen fragment that might be able to trick the skin to think that collagen broke down and it's time to create some new one. [more]
,
Palmitoyl Tetrapeptide-3
what‑it‑does cell-communicating ingredient
The pal of Palmitoyl Tripeptide-1 in Matrixyl 3000. A four amino acid peptide that works by reducing the production of the signal molecule, inteleukin-6 (IL-6) that promotes inflammation in the skin. [more]
,
Tyrosine, Glycolic Acid
what‑it‑does exfoliant
The most researched and well-known AHA exfoliant. It gently lifts off dead skin cells to reveal newer, fresher, smoother skin. In larger concentration (>10%) it's a proven collagen booster. [more]
,
Helianthus Annuus (Sunflower) Seed Oil
what‑it‑does emollient
irritancy, com. 0 0
Sunflower Oil - it's a great emollient that protects & enhances the skin barrier. [more]
,
Magnesium Aspartate, Zinc Gluconate
what‑it‑does anti-acne | soothing
A zinc salt known for its soothing and wound healing properties as well as for its anti-acne properties.  [more]
,
Rosmarinus Officinalis (Rosemary) Leaf Extract
what‑it‑does antioxidant | soothing | antimicrobial/antibacterial
Rosemary leaf extract - Its main active is rosmarinic acid, a potent antioxidant, and anti-inflammatory. It has also anti-bacterial, astringent and toning properties. [more]
,
Copper Gluconate
what‑it‑does soothing
A copper salt that is known to promote cellular regeneration and also has some antioxidant and tan-activating properties. [more]
,
Sodium Hyaluronate
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
,
Retinyl Palmitate
what‑it‑does cell-communicating ingredient
An ester form of vitamin A (retinol + palmitic acid) that is pretty much the least effective member of the retinoid family. Its anti-aging effects are quite questionable as well as its behavior in the presence of UVA light. (Use it at night if possible!) [more]
,
Echium Plantagineum Seed Oil
what‑it‑does solvent
,
Hydrolyzed Myrtus Communis Leaf Extract, Copper Tripeptide-1
what‑it‑does cell-communicating ingredient | soothing | antioxidant
A copper-peptide complex that has unique wound healing and skin remodelling properties. It's also an anti-inflammatory and antioxidant agent. [more]
,
Dimethicone
what‑it‑does emollient
irritancy, com. 0 1
A very common silicone that gives both skin and hair a silky smooth feel. It also forms a protective barrier on the skin and fills in fine lines. Also used for scar treatment. [more]
,
Disodium Edta
what‑it‑does chelating
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. [more]
,
Carbomer
what‑it‑does viscosity controlling
A handy white powder that magically converts a liquid into a nice gel formula. [more]
,
Ceteareth-20
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 3 2
A common functional ingredient that helps to keep the other ingredients together, stabilizes and thickens the products. [more]
,
Cyclopentasiloxane
what‑it‑does emollient | solvent
It's a super commonly used water-thin volatile silicone that gives skin and hair a silky, smooth feel.  [more]
,
Caprylyl Glycol
what‑it‑does moisturizer/humectant | emollient
A handy multi-tasking ingredient that gives the skin a nice, soft feel and also boosts the effectiveness of other preservatives. [more]
,
Cetearyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling | surfactant/cleansing
irritancy, com. 1 2
A common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products. [more]
,
Cyclohexasiloxane
what‑it‑does emollient | solvent
A light-feeling, volatile silicone that gives skin a unique, silky and non-greasy feel. It has excellent spreading properties and leaves no oily residue or build-up. 
,
Polysorbate 20
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0 0
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 
,
Zea Mays (Corn) Oil
what‑it‑does emulsifying | perfuming
,
Phenoxyethanol
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
,
Sorbic Acid
what‑it‑does preservative
A mild, natural preservative that usually comes to the formula together with its other mild preservative friends, such as Benzoic Acid and/or Dehydroacetic Acid. [more]
[less]
Water/Aqua/Eau, Glycerin, Isopropyl Palmitate, Cetearyl Alcohol, Glyceryl Stearate, PEG-100 Stearate, Butylene Glycol, Phosphatidylcholine, Tetrahexyldecyl Ascorbate, Dimethyl MEA, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-3, Tyrosine, Glycolic Acid, Helianthus Annuus (Sunflower) Seed Oil, Magnesium Aspartate, Zinc Gluconate, Rosmarinus Officinalis (Rosemary) Leaf Extract, Copper Gluconate, Sodium Hyaluronate, Retinyl Palmitate, Echium Plantagineum Seed Oil, Hydrolyzed Myrtus Communis Leaf Extract, Copper Tripeptide-1, Dimethicone, Disodium EDTA, Carbomer, Ceteareth-20, Cyclopentasiloxane, Caprylyl Glycol, Cetearyl Alcohol, Cyclohexasiloxane, Polysorbate 20, Zea Mays (Corn) Oil, Phenoxyethanol, Sorbic Acid

Highlights

Key Ingredients

Anti-acne: Zinc Gluconate
what‑it‑does anti-acne | soothing
A zinc salt known for its soothing and wound healing properties as well as for its anti-acne properties.  [more]
Antioxidant: Tetrahexyldecyl Ascorbate
what‑it‑does antioxidant | skin brightening
A stable, oil-soluble form of Vitamin C, that might have (in-vitro results) all the magic abilities of pure vitamin C (antioxidant, collagen booster, skin brightener). [more]
,
Rosmarinus Officinalis (Rosemary) Leaf Extract
what‑it‑does antioxidant | soothing | antimicrobial/antibacterial
Rosemary leaf extract - Its main active is rosmarinic acid, a potent antioxidant, and anti-inflammatory. It has also anti-bacterial, astringent and toning properties. [more]
,
Copper Tripeptide-1
what‑it‑does cell-communicating ingredient | soothing | antioxidant
A copper-peptide complex that has unique wound healing and skin remodelling properties. It's also an anti-inflammatory and antioxidant agent. [more]
Cell-communicating ingredient: Acetyl Hexapeptide-8
what‑it‑does cell-communicating ingredient | moisturizer/humectant
Argireline - famous peptide that's often referred to as "Botox in a jar". In reality, it's nowhere near that powerful, but it can smooth wrinkles to some extent by preventing facial muscles from contracting. [more]
,
Palmitoyl Tripeptide-1
what‑it‑does cell-communicating ingredient
A three amino acid peptide that is part of famous peptide duo, Matrixyl 3000. It's a type I collagen fragment that might be able to trick the skin to think that collagen broke down and it's time to create some new one. [more]
,
Palmitoyl Tetrapeptide-3
what‑it‑does cell-communicating ingredient
The pal of Palmitoyl Tripeptide-1 in Matrixyl 3000. A four amino acid peptide that works by reducing the production of the signal molecule, inteleukin-6 (IL-6) that promotes inflammation in the skin. [more]
,
Retinyl Palmitate
what‑it‑does cell-communicating ingredient
An ester form of vitamin A (retinol + palmitic acid) that is pretty much the least effective member of the retinoid family. Its anti-aging effects are quite questionable as well as its behavior in the presence of UVA light. (Use it at night if possible!) [more]
,
Copper Tripeptide-1
what‑it‑does cell-communicating ingredient | soothing | antioxidant
A copper-peptide complex that has unique wound healing and skin remodelling properties. It's also an anti-inflammatory and antioxidant agent. [more]
Exfoliant: Glycolic Acid
what‑it‑does exfoliant
The most researched and well-known AHA exfoliant. It gently lifts off dead skin cells to reveal newer, fresher, smoother skin. In larger concentration (>10%) it's a proven collagen booster. [more]
Skin brightening: Tetrahexyldecyl Ascorbate
what‑it‑does antioxidant | skin brightening
A stable, oil-soluble form of Vitamin C, that might have (in-vitro results) all the magic abilities of pure vitamin C (antioxidant, collagen booster, skin brightener). [more]
Skin-identical ingredient: Glycerin
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
,
Sodium Hyaluronate
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
Soothing: Zinc Gluconate
what‑it‑does anti-acne | soothing
A zinc salt known for its soothing and wound healing properties as well as for its anti-acne properties.  [more]
,
Rosmarinus Officinalis (Rosemary) Leaf Extract
what‑it‑does antioxidant | soothing | antimicrobial/antibacterial
Rosemary leaf extract - Its main active is rosmarinic acid, a potent antioxidant, and anti-inflammatory. It has also anti-bacterial, astringent and toning properties. [more]
,
Copper Gluconate
what‑it‑does soothing
A copper salt that is known to promote cellular regeneration and also has some antioxidant and tan-activating properties. [more]
,
Copper Tripeptide-1
what‑it‑does cell-communicating ingredient | soothing | antioxidant
A copper-peptide complex that has unique wound healing and skin remodelling properties. It's also an anti-inflammatory and antioxidant agent. [more]

Show all ingredients by function

Other Ingredients

Antimicrobial/antibacterial: Rosmarinus Officinalis (Rosemary) Leaf Extract
what‑it‑does antioxidant | soothing | antimicrobial/antibacterial
Rosemary leaf extract - Its main active is rosmarinic acid, a potent antioxidant, and anti-inflammatory. It has also anti-bacterial, astringent and toning properties. [more]
Buffering: Dimethyl Mea
what‑it‑does buffering
Chelating: Disodium Edta
what‑it‑does chelating
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. [more]
Emollient: Isopropyl Palmitate
what‑it‑does emollient
irritancy, com. 1 4
A clear, colorless emollient ester (oily liquid) that makes the skin nice and smooth. [more]
,
Cetearyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling | surfactant/cleansing
irritancy, com. 1 2
A common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products. [more]
,
Glyceryl Stearate
what‑it‑does emollient | emulsifying
Waxy, white, solid stuff that helps water and oil to mix together and leaves the skin feeling soft and smooth. [more]
,
Helianthus Annuus (Sunflower) Seed Oil
what‑it‑does emollient
irritancy, com. 0 0
Sunflower Oil - it's a great emollient that protects & enhances the skin barrier. [more]
,
Dimethicone
what‑it‑does emollient
irritancy, com. 0 1
A very common silicone that gives both skin and hair a silky smooth feel. It also forms a protective barrier on the skin and fills in fine lines. Also used for scar treatment. [more]
,
Cyclopentasiloxane
what‑it‑does emollient | solvent
It's a super commonly used water-thin volatile silicone that gives skin and hair a silky, smooth feel.  [more]
,
Caprylyl Glycol
what‑it‑does moisturizer/humectant | emollient
A handy multi-tasking ingredient that gives the skin a nice, soft feel and also boosts the effectiveness of other preservatives. [more]
,
Cetearyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling | surfactant/cleansing
irritancy, com. 1 2
A common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products. [more]
,
Cyclohexasiloxane
what‑it‑does emollient | solvent
A light-feeling, volatile silicone that gives skin a unique, silky and non-greasy feel. It has excellent spreading properties and leaves no oily residue or build-up. 
Emulsifying: Cetearyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling | surfactant/cleansing
irritancy, com. 1 2
A common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products. [more]
,
Glyceryl Stearate
what‑it‑does emollient | emulsifying
Waxy, white, solid stuff that helps water and oil to mix together and leaves the skin feeling soft and smooth. [more]
,
Peg-100 Stearate
what‑it‑does surfactant/cleansing | emulsifying
irritancy, com. 0 1
A commonly used water-soluble surfactant and emulsifier. [more]
,
Phosphatidylcholine
what‑it‑does emulsifying
,
Ceteareth-20
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 3 2
A common functional ingredient that helps to keep the other ingredients together, stabilizes and thickens the products. [more]
,
Cetearyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling | surfactant/cleansing
irritancy, com. 1 2
A common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products. [more]
,
Polysorbate 20
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0 0
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 
,
Zea Mays (Corn) Oil
what‑it‑does emulsifying | perfuming
Moisturizer/humectant: Glycerin
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
,
Butylene Glycol
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
,
Acetyl Hexapeptide-8
what‑it‑does cell-communicating ingredient | moisturizer/humectant
Argireline - famous peptide that's often referred to as "Botox in a jar". In reality, it's nowhere near that powerful, but it can smooth wrinkles to some extent by preventing facial muscles from contracting. [more]
,
Sodium Hyaluronate
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
,
Caprylyl Glycol
what‑it‑does moisturizer/humectant | emollient
A handy multi-tasking ingredient that gives the skin a nice, soft feel and also boosts the effectiveness of other preservatives. [more]
Preservative: Phenoxyethanol
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
,
Sorbic Acid
what‑it‑does preservative
A mild, natural preservative that usually comes to the formula together with its other mild preservative friends, such as Benzoic Acid and/or Dehydroacetic Acid. [more]
Solvent: Water/Aqua/Eau
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
,
Butylene Glycol
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
,
Echium Plantagineum Seed Oil
what‑it‑does solvent
,
Cyclopentasiloxane
what‑it‑does emollient | solvent
It's a super commonly used water-thin volatile silicone that gives skin and hair a silky, smooth feel.  [more]
,
Cyclohexasiloxane
what‑it‑does emollient | solvent
A light-feeling, volatile silicone that gives skin a unique, silky and non-greasy feel. It has excellent spreading properties and leaves no oily residue or build-up. 
Surfactant/cleansing: Cetearyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling | surfactant/cleansing
irritancy, com. 1 2
A common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products. [more]
,
Peg-100 Stearate
what‑it‑does surfactant/cleansing | emulsifying
irritancy, com. 0 1
A commonly used water-soluble surfactant and emulsifier. [more]
,
Ceteareth-20
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 3 2
A common functional ingredient that helps to keep the other ingredients together, stabilizes and thickens the products. [more]
,
Cetearyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling | surfactant/cleansing
irritancy, com. 1 2
A common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products. [more]
,
Polysorbate 20
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0 0
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 
Viscosity controlling: Cetearyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling | surfactant/cleansing
irritancy, com. 1 2
A common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products. [more]
,
Carbomer
what‑it‑does viscosity controlling
A handy white powder that magically converts a liquid into a nice gel formula. [more]
,
Cetearyl Alcohol
what‑it‑does emollient | emulsifying | viscosity controlling | surfactant/cleansing
irritancy, com. 1 2
A common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products. [more]

Skim through

Ingredient name what-it-does irr., com. ID-Rating
Water/Aqua/Eau solvent
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Isopropyl Palmitate emollient 1, 4
Cetearyl Alcohol emollient, emulsifying, viscosity controlling, surfactant/​cleansing 1, 2
Glyceryl Stearate emollient, emulsifying
Peg-100 Stearate surfactant/​cleansing, emulsifying 0, 1
Butylene Glycol moisturizer/​humectant, solvent 0, 1
Phosphatidylcholine emulsifying
Tetrahexyldecyl Ascorbate antioxidant, skin brightening goodie
Dimethyl Mea buffering
Acetyl Hexapeptide-8 cell-communicating ingredient, moisturizer/​humectant goodie
Palmitoyl Tripeptide-1 cell-communicating ingredient goodie
Palmitoyl Tetrapeptide-3 cell-communicating ingredient goodie
Tyrosine
Glycolic Acid exfoliant superstar
Helianthus Annuus (Sunflower) Seed Oil emollient 0, 0 goodie
Magnesium Aspartate
Zinc Gluconate anti-acne, soothing goodie
Rosmarinus Officinalis (Rosemary) Leaf Extract antioxidant, soothing, antimicrobial/​antibacterial goodie
Copper Gluconate soothing goodie
Sodium Hyaluronate skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Retinyl Palmitate cell-communicating ingredient
Echium Plantagineum Seed Oil solvent
Hydrolyzed Myrtus Communis Leaf Extract
Copper Tripeptide-1 cell-communicating ingredient, soothing, antioxidant goodie
Dimethicone emollient 0, 1
Disodium Edta chelating
Carbomer viscosity controlling
Ceteareth-20 emulsifying, surfactant/​cleansing 3, 2
Cyclopentasiloxane emollient, solvent
Caprylyl Glycol moisturizer/​humectant, emollient
Cetearyl Alcohol emollient, emulsifying, viscosity controlling, surfactant/​cleansing 1, 2
Cyclohexasiloxane emollient, solvent
Polysorbate 20 emulsifying, surfactant/​cleansing 0, 0
Zea Mays (Corn) Oil emulsifying, perfuming
Phenoxyethanol preservative
Sorbic Acid preservative

Ingredients explained

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

Glycerin - goodie
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • Super common, used for more than 50 years
  • Not only a simple moisturizer but plays an important role in keeping the stuff between our skin cells healthy
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

What-it-does: emollient | Irritancy: 1 | Comedogenicity: 4

A clear, colorless emollient ester (oily liquid from isopropyl alcohol + palmitic acid) that makes the skin nice and smooth. It has very good spreading properties and gives a silky touch to the products.

What-it-does: emollient, emulsifying, viscosity controlling, surfactant/cleansing | Irritancy: 1 | Comedogenicity: 2

A super common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products

It’s a so-called fatty alcohol (a mix of cetyl and stearyl alcohol - other two emollient fatty alcohols).  Though alcohol is in its name, its properties are totally different from the properties of “normal” alcohol, or denat. alcohol. It’s not drying and not irritating and totally ok for the skin.

What-it-does: emollient, emulsifying

A super common, waxy, white, solid stuff that helps water and oil to mix together and leaves the skin feeling soft and smooth.

It can be produced from most vegetable oils in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.

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It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".

What-it-does: surfactant/cleansing, emulsifying | Irritancy: 0 | Comedogenicity: 1

A very common water-loving surfactant and emulsifier that helps to keep water and oil mixed nicely together. 

It's often paired with glyceryl stearate - the two together form a super effective emulsifier duo that's salt and acid tolerant and works over a wide pH range. It also gives a "pleasing product aesthetics", so no wonder it's popular.

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

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It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive. 

What-it-does: emulsifying

We don't have description for this ingredient yet.

Also-called: Form of Vitamin C, Ascorbyl Isotetrapalmitate, Ascorbyl Tetraisopalmitate, ATIP | What-it-does: antioxidant, skin brightening

Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of skincare big shot Vitamin C. If you do not know, why Vitamin C is such a big deal in skincare, click here and read all about it. We are massive vitamin C fans and have written about it in excruciating detail.

So now, you know that Vitamin C is great and all but, it's really unstable and gives cosmetics companies many headaches. To solve this problem they came up with vitamin C derivatives, and one of them is Tetrahexyldecyl Ascorbate (let's call it ATIP in short).

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It's a really promising candidate (see below), but while reading all the goodness about it in a minute, do not forget that derivatives not only have to be absorbed into the skin but also have to be converted to pure vitamin C (ascorbic acid or AA) and the efficacy of the conversion is often unknown. In addition, vitamin C's three magic properties (antioxidant, collagen booster, skin brightener) are all properly proven in-vivo (on real people), but for the derivatives, it's mostly in-vitro studies or in the case of ATIP, it's in-vitro and done by an ingredient supplier.

With this context in mind let's see what ATIP might be able to do. First, it is stable (if pH < 5), easy to formulate and a joy to work with for a cosmetic chemist.

Second, because it's oil-soluble, its skin penetration abilities seem to be great. So great in fact, that it surpasses the penetration of pure vitamin C threefold at the same concentration and it penetrates successfully into the deeper layers of the skin (that is usually important to do some anti-aging work). There is also in-vitro data showing that it converts to AA in the skin. 

Third, ATIP seems to have all three magic abilities of pure vitamin C: it gives antioxidant protection from both UVB and UVA rays, it increases collagen synthesis (even more than AA) and it has a skin brightening effect by reducing melanogenesis by more than 80% in human melanoma cell cultures.

So this all sounds really great, but these are only in-vitro results at this point. We could find Tetrahexyldecyl Ascorbate mentioned only in one published in-vivo study that examined the anti-aging properties of a silicone formula containing 10% AA and 7% ATIP. The authors theorized that the 10% AA is released slowly from the silicon delivery system and probably stays in the upper layer of the skin to give antioxidant benefits, while ATIP penetrates more rapidly and deeply and gives some wrinkle-reducing benefits. The study was a small (10 patients), double-blind experiment, and the formula did show some measurable anti-aging results. However, it is hard to know how much pure vitamin C or ATIP can be thanked.

Bottom line: a really promising, but not well-proven vitamin C derivative that can be worth a try especially if you like experimenting (but if you like the tried and true, pure vitamin C will be your best bet).

Also-called: DMAE | What-it-does: buffering

We don't have description for this ingredient yet.

Also-called: Argireline, Acetyl Hexapeptide-3 | What-it-does: cell-communicating ingredient, moisturizer/humectant

If you see a cosmetic product that claims that it has "Botox-like effect" then two things are almost certain: one, the product overpromises and two, it contains Argireline. 

So this one is the famous peptide that's marketed by its manufacturer as the "Botox in a jar". The basis for this claim is that it targets the same wrinkle forming mechanism (wrinkles caused by facial muscle movement) as Botox, but the way it works is very different. In addition, the extent to which it can prevent muscles from contracting (and to smooth wrinkles) is very different (otherwise why would anyone use still Botox?). 

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The manufacturer did several studies to prove that Argireline really works and it does (just not as well as Botox). In-vivo (made on real people) tests showed that using 10% Argireline solution around the eyes for 15 days decreased wrinkles depth by 17%. A Spanish University also did some research and found that Argireline increased the level of skin moisturization and decreased both the depth and width of wrinkles "significantly". 

This means, Acetyl Hexapeptide-8 does have some ability to smooth wrinkles (but not as well as Botox - sorry, if we sound like a broken record). Also, we have to agree with TruthInAging, that it's not a collagen builder and not a preventer of structural aging (think vitamin C, AHAs or retinol); it's just a quick fix. If you are looking for one, this could be your thing. If you are more of a "let's treat this aging thing properly" type, then it's probably not your thing.

Also-called: Part of Matrixyl 3000, Pal-GHK, Formerly also Palmitoyl Oligopeptide | What-it-does: cell-communicating ingredient

A really famous peptide that is part of Matrixyl 3000, the most sold peptide complex in the word. Before we go and find out what the big deal with Matrixyl 3000 is, let's just focus on Palmitoyl Tripeptide-1 itself for a bit.

It's a small three amino acid (they are the building blocks of all proteins) peptide with the amino sequence of glycine-histidine-lysine, or GHK. GHK is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration. 

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The GHK part is the important one as it's a type I collagen fragment. When collagen naturally breaks down in the skin, the resulting peptide fragments signal to the skin that it should get to work and create some nice, new collagen. Adding in collagen fragment peptides, like GHK, might trick the skin into thinking that collagen has broken down and it's time to create some more.

Therefore, Palmitoyl Tripeptide-1 is believed to be able to stimulate collagen production in the skin, and more collagen means fewer wrinkles and younger looking skin. 

In Matrixyl 3000, Palmitoyl Tripeptide-1 is coupled with Palmitoyl Tetrapeptide-7  and the duo works in synergy to reduce wrinkles and give younger looking skin. According to the manufacturer's in-vivo (made on real people) test, applying 3% Matrixyl 3000 twice a day for 2 months resulted in all of the following things:

  • 39.4% reduction in surface occupied by deep wrinkles
  • 32.9% reduction in main wrinkle density
  • 19.9% reduction in main wrinkle average depth
  • 16% improvement in roughness
  • 16.2% in lifting effect
  • 5.5% improvement in elasticity
  • 15.5% improvement in skin tone

Manufacturer results, of course, always have to be taken with a pinch of salt, but if you like peptides, the Matryxil 3000 duo is one of the best-proven and most well-known ones and it's something that is worth trying.

Also-called: Part of Matrixyl 3000, Pal-GQPR, Previously Palmitoyl Tetrapeptide-3 | What-it-does: cell-communicating ingredient

A four amino acid peptide with the amino sequence of glycine-glutamine-proline-arginine. It is attached to palmitic acid (a fatty acid)  to increase oil solubility and skin penetration. 

It works by reducing the production of the signal moleculeinteleukin-6 (IL-6) which promotes inflammation in the skin and less inflammation means slower degradation of important things (like collagen) that results in younger looking skin for a longer time. 

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It works in synergy with its pal, Palmitoyl Tripeptide-1 in the famous Matrixyl 3000 complex. You can read some more about the famous duo here.

We don't have description for this ingredient yet.

Glycolic Acid - superstar
What-it-does: exfoliant
  • It’s the most researched AHA with the most proven skin benefits
  • It gently lifts off dead skin cells to reveal newer, fresher, smoother skin
  • It can help skin’s own collagen production that results in firmer, younger skin
  • It can fade brown spots caused by sun damage or PIH
  • Choose a product where you know the concentration and pH value because these two greatly influence effectiveness
  • Don’t forget to use your sunscreen (in any case but especially so next to an AHA product)
  • Slight stinging or burning with a stronger AHA product is normal
  • If your skin is very sensitive, rosacea prone choose rather a BHA or PHA product
Read all the geeky details about Glycolic Acid here >>

Also-called: Sunflower Oil | What-it-does: emollient | Irritancy: 0 | Comedogenicity: 0

Sunflower does not need a big intro as you probably use it in the kitchen as cooking oil, or you munch on the seeds as a healthy snack or you adore its big, beautiful yellow flower during the summer - or you do all of these and probably even more. And by even more  we mean putting it all over your face as sunflower oil is one of the most commonly used plant oils in skincare.

It’s a real oldie: expressed directly from the seeds, the oil is used not for hundreds but thousands of years. According to The National Sunflower Association, there is evidence that both the plant and its oil were used by American Indians in the area of Arizona and New Mexico about 3000 BC. Do the math: it's more than 5000 years – definitely an oldie.

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Our intro did get pretty big after all (sorry for that), so let's get to the point finally: sunflower oil - similar to other plant oils - is a great emollient that makes the skin smooth and nice and helps to keep it hydrated. It also protects the surface of the skin and enhances the damaged or irritated skin barrier. Leslie Bauman notes in Cosmetic Dermatology that one application of sunflower oil significantly speeds up the recovery of the skin barrier within an hour and sustains the results 5 hours after using it.

It's also loaded with fatty acids (mostly linoleic (50-74%)  and oleic (14-35%)). The unrefined version (be sure to use that on your skin!) is especially high in linoleic acid that is great even for acne-prone skin. Its comedogen index is 0, meaning that it's pretty much an all skin-type oil

Truth be told, there are many great plant oils and sunflower oil is definitely one of them.

We don't have description for this ingredient yet.

Zinc Gluconate - goodie
What-it-does: anti-acne, soothing

If you are fighting acne and have looked into oral supplements, chances are that zinc gluconate sounds familiar to you. It is a zinc salt that has research proving it to be effective against inflammatory acne, though not quite as effective as the antibiotic minocycline (31.2% vs. 63.4% success rate). However, zinc supplements are easily available, have little-to-no side effects, so supplementing them with a 30mg per day dose can still be a good idea.

As for smearing zinc gluconate all over your face, it is also not a bad idea. Zinc has multiple magic abilities: it is antibacterial (including evil, acne-causing P. acnes) and sebum-regulating (5α-reductase inhibitor), great for acne-prone skin types. It also stimulates antioxidant enzyme systems (mainly superoxide dismutase) and has nice wound healing abilities acting mainly in the first, proliferation phase. So great for skin types in need of healing and soothing.

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What about the gluconate part? It is there to promote the absorption and bioavailability of zinc and also plays a role in cellular regeneration (involved in the synthesis of ribose sugars, structural components of DNA and RNA).

Also-called: Rosemary Leaf Extract | What-it-does: antioxidant, soothing, antimicrobial/antibacterial

The extract coming from the lovely herb, rosemary. It contains lots of chemicals, including flavonoids, phenolic acids, and diterpenes. Its main active is rosmarinic acid, a potent antioxidant, and anti-inflammatory. It has also anti-bacterial, astringent and toning properties. 

The leaves contain a small amount of essential oil (1-2%) with fragrant components, so if you are allergic to fragrance, it might be better to avoid it. 

Copper Gluconate - goodie
What-it-does: soothing

A copper salt (copper cation + gluconate anion) probably best known for promoting cellular regeneration and wound healing. It works mainly in the final healing phase that complements nicely with the wound healing abilities of its mineral salt sister, zinc gluconate

Other than that, copper is also involved in several enzyme systems: it is a cofactor for the antioxidant enzyme, superoxide dismutase and also a cofactor for the melanin stimulating enzyme, tyrosinase. This means that copper has some tan activating properties, though we think you should not be into tanning at all, as UV is so bad for the skin

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The gluconate part is there to promote the bioavailability of copper and it also plays a role in cellular regeneration (involved in the synthesis of ribose sugars, structural components of DNA and RNA).

What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It’s the - sodium form - cousin of the famous NMFhyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

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In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).

What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists. 

If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).

Also-called: Form of Retinoids | What-it-does: cell-communicating ingredient

It's an ester form of vitamin A (retinol + palmitic acid) that belongs to the "retinoid family". The retinoid family is pretty much the royal family of skincare, with the queen being the FDA-approved anti-aging ingredient tretinoin. Retinol is also a very famous member of the family, but it's like Prince William, two steps away from the throne. Retinyl palmitate will be then little Prince George, quite far (3 steps) away from the throne. 

By steps, we mean metabolic steps. Tretinoin, aka retinoic acid, is the active ingredient our skin cells can understand and retinyl palmitate (RP) has to be converted by our metabolic machinery to actually do something. The conversion is a 3 step one and looks like this:

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retinyl palmitate --> retinol -- > retinaldehyde --> all-trans-retinoic acid

As we wrote in our lengthy retinol description the problem is that the conversion is not terribly effective. The evidence that RP is still an effective anti-aging ingredient is not very strong, in fact, it's weak. Dr. Leslie Baumann in her fantastic Cosmetic Dermatology book writes that RP is topically ineffective

What's more, the anti-aging effectiveness is not the only questionable thing about RP. It also exibits questionable behaviour in the presence of UV light and was the center of a debate between the non-profit group, EWG (whose intentions are no doubt good, but its credibility is often questioned by scientists) and a group of scientists and dermatologists lead by Steven Q. Wang, MD,  director of dermatologic surgery at Memorial-Sloan Kettering Cancer Centre. 

Dr. Leslie Baumann wrote a great review of the debate and summarized the research available about retinyl palmitate here.  It seems that there is a study showing RP being photo protective against UVB rays but there is also a study showing RP causing DNA damage and cytotoxicity in association with UVA. 

We think that the truth lies somewhere in the middle, and we agree with Dr. Baumann's conclusion: "sufficient evidence to establish a causal link between RP and skin cancer has not been produced. Nor, I’m afraid, are there any good reasons to recommend the use of RP". We would add especially during the day!

Bottom line: If you wanna get serious about retinoids, RP is not your ingredient (retinol or tretinoin is!). However, if you use a product that you like and it also contains RP, there is no reason to throw it away. If possible use it at night, just to be on the safe side.

What-it-does: solvent

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Also-called: GHK-Cu | What-it-does: cell-communicating ingredient, soothing, antioxidant
  • GHK-Cu is a copper-peptide complex found naturally in yucky bodily fluids (plasma, saliva, and urine)
  • It has unique wound healing properties by stimulating the breakdown of unhealthy, too large collagen in scar tissue and stimulating nice and healthy collagen production afterwards
  • It stimulates the production of several important skin-identical ingredients (e.g. collagen, elastin, and glycosaminoglycans)
  • It has significant anti-inflammatory and antioxidant effect
  • There are a few promising studies showing GHK-Cu can improve skin elasticity, clarity, firmness and reduce lines and wrinkles
  • It can improve hair growth by enlarging hair follicles (and bigger follicles produce longer, thicker hair)
  • There are some urban legends about possible overdosing or facial hair problems (read more in geeky details)
Read all the geeky details about Copper Tripeptide-1 here >>

What-it-does: emollient | Irritancy: 0 | Comedogenicity: 1

Probably the cheapest and most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.

As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier. Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity. 

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As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types). 

What-it-does: chelating

Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.

What-it-does: viscosity controlling

A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula. If you see gel in the name of a moisturizer type thing, chances are carbomer will be in the ingredient list. 

What-it-does: emulsifying, surfactant/cleansing | Irritancy: 3 | Comedogenicity: 2

A common functional ingredient that helps to keep the other ingredients together, stabilizes and thickens the products. It also helps water to mix with oils and dirt - a useful thing for cleaning the skin and hair.

If you are a chemist geek you might want to know that it’s made from the mixture of Cetearyl alcohol (a fatty alcohol - the nice type of alcohols) and ethylene oxide. The numerical value at the end of the ingredient name marks the average number of ethylene oxide molecules added. 20 seems to be a common choice.

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It’s normally used at 1-3% concentration.

What-it-does: emollient, solvent

A super commonly used 5 unit long, cyclic structured silicone that is water-thin and does not stay on the skin but evaporates from it (called volatile silicone). Similar to other silicones, it gives skin and hair a silky, smooth feel

It's often combined with the non-volatile (aka stays on the skin) dimethicone as the two together form a water-resistant, breathable protective barrier on the skin without a negative tacky feel.

It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol

The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.

What-it-does: emollient, emulsifying, viscosity controlling, surfactant/cleansing | Irritancy: 1 | Comedogenicity: 2

A super common multitasker ingredient that gives your skin a nice soft feel (emollient). It also helps water and oil to blend (emulsifier) and to thicken up products

It’s a so-called fatty alcohol (a mix of cetyl and stearyl alcohol - other two emollient fatty alcohols).  Though alcohol is in its name, its properties are totally different from the properties of “normal” alcohol, or denat. alcohol. It’s not drying and not irritating and totally ok for the skin.

What-it-does: emollient, solvent

A light-feeling, volatile (meaning it does not absorb into the skin but evaporates from it) silicone that gives skin a unique, silky and non-greasy feel. It has excellent spreading properties and leaves no oily residue or build-up. 

What-it-does: emulsifying, surfactant/cleansing | Irritancy: 0 | Comedogenicity: 0

It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 

Also-called: Corn Oil | What-it-does: emulsifying, perfuming

We don't have description for this ingredient yet.

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

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Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10). 

It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.

What-it-does: preservative

A mild, natural preservative that usually comes to the formula together with its other mild preservative friends, such as Benzoic Acid and/or Dehydroacetic Acid. Btw, it's also used as a food preservative.

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