Bioretinol Effect Lifting Anti-wrinkle Cream 50+
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Bielenda Bioretinol Effect Lifting Anti-wrinkle Cream 50+Ingredients explained
The flower water coming from the flowers of the Damask Rose. In general, flower waters (also called hydrosols) are diluted versions of essential oils coming from the same plant. They contain the same components but in much-reduced concentrations.
Similar to its big sister, rose oil, rose water also has a lovely, relaxing scent. It contains some antioxidant and antimicrobial compounds, as well as some fragrant components.
If your skin is super sensitive, it is a good idea to choose products without fragrant floral waters.
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved.
It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula.
When it comes to cosmetic oils and hype, argan oil is for sure leading the way. Dubbed as the "liquid gold of Morocco", we have to admit we have some trouble determining why this oil enjoys such a special miracle status. Not that it's not good, it is good, even great but reading the research about argan and a bunch of other plant oils we just do not see the big, unique differentiating factor (though that might be our fault not reading enough, obvs.)
So, argan oil comes from the kernel of the argan fruit that comes from the argan tree that grows only in Morocco. The tree is slow growing and getting the oil is a hard job. The traditional process is that the ripe argan fruits fall from the tree, then goats eat them up and poop out the seeds. The seeds are collected and smashed with a stone to get the kernels inside. This part is the hard one as the seeds have extremely hard shells. Once the kernels are obtained, the oil is pressed out from them (the kernels contain about 50% oil).
As for skincare, argan oil is loaded with lots of skin goodies (but so are many other plant oils): it contains 80% nourishing and moisturizing unsaturated fatty acids, mainly oleic (38-50%), linoleic (28-38%) and palmitic (10-18%). It also contains a relatively large amount of antioxidant vitamin E (600-900 mg/kg, about twice as much as olive), small amounts of antioxidant phenols (including caffeic acid, ferulic acid, and epicatechin), as well as some rare sterols with soothing and anti-inflammatory properties.
Thanks to all the above goodness in argan oil, it can greatly nourish and moisturize the skin and hair. It's also claimed to be able to neutralize collagen-damaging free radicals, help reduce scars, and revitalize and improve skin elasticity. You can even read that argan might help acne-prone skin, but being a high oleic oil, we would be careful with that.
All in all, argan oil is a real goodie but we do not fully understand the special miracle status it enjoys.
A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular.
It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life.
It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy.
Another advantage of squalane is that it is pretty much compatible with all skin types and skin conditions. It is excellent for acne-prone skin and safe to use even if you have fungi-related skin issues, like seborrhea or fungal acne.
The unsaturated (with double bonds) and hence less stable version of Squalane is Squalene, you can read about it here >>
There is definitely some craze going on for coconut oil both in the healthy eating space (often claimed to be the healthiest oil to cook with but this is a topic for another site) and in the skin and hair care space.
We will talk here about the latter two and see why we might want to smear it all over ourselves. Chemically speaking, coconut oil has a unique fatty acid profile. Unlike many plant oils that mostly contain unsaturated fatty acids (fatty acids with double bonds and kinky structure such as linoleic or oleic), coconut oil is mostly saturated (fatty acids with single bonds only) and its most important fatty acid is Lauric Acid (about 50%). Saturated fatty acids have a linear structure that can stack nice and tight and hence they are normally solid at room temperature. Coconut oil melts around 25 °C so it is solid in the tub but melts on contact with the skin.
The saturated nature of coconut oil also means that it is a heavy-duty-oil ideal for dry skin types. A double-blind research confirmed that extra virgin coconut oil is as effective in treating xerosis (aka very dry skin) as mineral oil. Another study found that coconut oil is more effective than mineral oil in treating mild to moderate atopic dermatitis (aka eczema) in children.
So when it comes to dry skin, coconut oil is a goodie, no question there. The question is if it is good or bad for acne-prone skin. Its main fatty acid, Lauric Acid has some research showing that it is a promising ingredient against evil acne-causing bacteria, P. acnes but at the same time, both Lauric Acid and coconut oil have a very high comedogenic rating (4 out of 5). Though comedogenic ratings are not very reliable, anecdotal evidence (i.e. people commenting in forums) shows that people have mixed experiences. While some claim that it worked wonders on their acne others say that it gave them serious blackheads and zits. Try it at your own risk.
As for hair care, coconut oil has pretty solid research showing that it can penetrate into the hair very well (better than mineral oil and sunflower oil) and it can prevent hair protein loss as well as combing damage. If you have problems with damaged hair, split ends, coconut oil is worth trying as a pre- or/and post-wash treatment. Labmuffin has an awesome blogpost explaining in more detail why coconut oil is good for your hair.
A couple of other things worth mentioning: coconut oil might help with wound healing (promising animal study), it has some antifungal activity (against dermatophytes that cause the thing known as ringworm) and it also works as an insect repellent against black flies.
Overall, coconut oil is definitely a goodie for the hair and dry skin. If that warrants for the magic oil status it enjoys, we don't know.
An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.
It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols. Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.
A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.
Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.
It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".
A glycerin and stearic acid based ingredient that helps oil and water to mix nicely together, aka emulsifier. It is PEG-free and based on renewable raw materials.
It usually comes to the formula with its emulsifier buddy, Polyglyceryl-6 Behenate, and the duo is especially recommended for formulating low-viscous serums, lotions, and sprays. As an added bonus, the duo is also described as providing "outstanding moisturization properties".
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version.
According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E.
At first glance, you could think that Bakuchiol is your average plant extract. It is derived from the seeds of Psoralea Corylifolia, aka Babchi, a plant important in Indian and Chinese medicine. The molecule was first isolated in 1973 and several anti-something properties are known about it: it has anti-inflammatory, antioxidant, anti-tumor, anti-bacterial and hepatoprotective magical abilities like plenty of other Ayurvedic plant extracts.
What makes Bakuchiol a special snowflake is the recent discovery that it behaves on the skin in a way very similar to well-known skincare superstar, retinol. While chemically, it has nothing to do with the vitamin-A family, aka retinoids, comparative gene expression profiling (a fancy way of saying that they compared how retinol and bakuchiol modify the way skin cells behave and produce important skin proteins such as collagen) shows that retinol and bakuchiol regulate skin cell behavior in a similar way.
To be more specific, both Bakuchiol and retinol upregulate collagen I, III and IV production and downregulate MMP, the evil collagen attacking enzyme in our skin. This means more collagen stays in our skin and we all know that more collagen equals firmer, more wrinkle-free skin. A 12-week clinical study using a 0.5% Bakuchiol formula with 17 people using it twice a day confirmed a significant improvement in lines and wrinkles, elasticity, firmness and an overall reduction in photo-damage. Also, the test formula was very well tolerated, without any retinol-like side effects.
What's more, a 2018 double-blind study with 44 people compared 0.5% Bakuchiol with 0.5% retinol cream and found that "bakuchiol is comparable to retinol in its ability to improve photoaging and is better tolerated than retinol". A super promising result after 12 weeks.
If you are not a daredevil-type who doesn't want to stop using a super well-proven retinol for a newbie like Bakuchiol, we have good news. The two also work very nicely together and Bakuchiol can actually help to stabilize the otherwise unstable and hard to formulate retinol.
And we are still not done, as Bakuchiol shows not only anti-aging properties but also nice anti-acne effects. 1% Bakuchiol seems to be very effective in itself (57% reduction in acne after 6 weeks treatment) and even better when combined with 2% salicylic acid (67% reduction in acne after 6 weeks). We like that Bakuchiol is such a good team player! The molecule works against acne in multiple ways: It downregulates 5α-reductase (a sebum-controlling enzyme), it is antibacterial (including P. acnes), anti-inflammatory and it inhibits lipid-peroxidation, an evil oxidative process that is recently thought to be a very early trigger in the acne process.
We feel that this description is becoming very long so we will just mention that Bakuchiol also seems to positively regulate hydration-related genes such as Aquaporin 3 and also shows some melanin-inhibiting properties.
Overall, we think Bakuchiol is an awesome molecule with lots of promise both for anti-aging and anti-acne. But the proof compared to the well-established superstars is far from solid, so in a skincare routine, we would rather add Bakuchiol next to retinol than straight up replace it. Unless you are a gimme-the-newest-shiny-thing-under-the-sun-type.
We don't have description for this ingredient yet.
The emollient plant oil coming from the seeds of the cactus commonly called Prickly Pear or Nopal Fig. It is a native to Mexico cactus with large, sweet fruits that are used to create jam and jellies. About 18–20% of the peeled fruits are seeds, and the seeds contain only about 3-5% oil. This means that the oil is rare and expensive as a ton of fruit (and it is literally a ton) is needed to yield 1 liter of it.
As for its composition, its three main fatty acids are barrier-repairing linoleic (60-70%), nourishing oleic (9-26%), and saturated fatty acid, palmitic (8-18%). It is also rich in antioxidant vitamin E (110mg/100g) and in anti-inflammatory sterols (beta-sitosterol, campesterol). As a high-linoleic oil, it has a light skin feeling, absorbs easily into the top layer of the skin and gives a velvety skin feel.
One of the many types of ceramides that can be found naturally in the upper layer of the skin. Ceramides make up about 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated. It works even better when combined with its pal, Ceramide 1.
We wrote way more about ceramides at ceramide 1, so click here to know more.
Super common soothing ingredient. It can be found naturally in the roots & leaves of the comfrey plant, but more often than not what's in the cosmetic products is produced synthetically.
It's not only soothing but it' also skin-softening and protecting and can promote wound healing.
The oil coming from the pulp of one of the most nutritious fruits in the world, the avocado. It's loaded with the nourishing and moisturizing fatty acid, oleic (70%) and contains some others including palmitic (10%) and linoleic acid (8%). It also contains a bunch of minerals and vitamins A, E and D.
Avocado oil has extraordinary skin penetration abilities and can nourish different skin layers. It's a very rich, highly moisturizing emollient oil that makes the skin smooth and nourished. Thanks to its vitamin E content it also has some antioxidant properties. As a high-oleic plant oil, it is recommended for dry skin.
An emollient plant oil coming from the Sacha Inchi plant from the Colombian Amazon.
Similar to other plant oils, it's loaded with nourishing and moisturizing fatty acids: it's especially rich in α-Linolenic acid (42-49%) and linoleic acid (32-38%) and contains less oleic acid (9-14%). It also contains a decent amount of antioxidant vitamin E (200 mg/kg).
You probably know olive oil from the kitchen as a great and healthy option for salad dressing but it's also a great and healthy option to moisturize and nourish the skin, especially if it's on the dry side.
Similar to other emollient plant oils, it's loaded with nourishing fatty acids: oleic is the main component (55-83%), and also contains linoleic (3.5-20%) and palmitic acids (7-20%). It also contains antioxidant polyphenols, tocopherols (types of vitamin E) and carotenoids and it's one of the best plant sources of skin-identical emollient, Squalene.
Overall, a great option for dry skin but less so for acne-prone or damaged skin.
We don't have description for this ingredient yet.
A glycerin and behenic acid based ingredient that stabilizes oil-water mixes, aka emulsions. It usually comes to the formula with Polyglyceryl-6 Stearate, and the duo is helpful for making light serums and lotions. As an added bonus, they also work as a nice emollient and moisturizer.
A glycerin-derived gentle cleansing agent that is described as being skin and eye-friendly, and not leaving the skin dry or tight. It's also used as a co-emulsifier or solubilizer that helps to blend small amounts of oily things into water-based products.
- Primary fat-soluble antioxidant in our skin
- Significant photoprotection against UVB rays
- Vit C + Vit E work in synergy and provide great photoprotection
- Has emollient properties
- Easy to formulate, stable and relatively inexpensive
We don't have description for this ingredient yet.
Squalene is an oily liquid that originally comes from shark liver but luckily it can also be found in a couple of plant oils. Olive (0.6%), peanut (0.1%) and pumpkin (0.35%) oils contain it, though not in huge amounts.
What contains more of it, is the sebum (the oily stuff) that our skin produces. About 13% of human sebum is squalene, which means that it’s an important skin-identical ingredient and NMF (natural moisturizing factor).
Chemically speaking, it is an unsaturated (has double bonds) hydrocarbon (contains only carbon and hydrogen) molecule, that can undergo oxidation. On the pro side, this means that squalene can act as an antioxidant (while its no-double-bond version sister, squalane cannot), but on the con side, squalene is less stable and has a shorter shelf life.
This is probably the main reason why its no-double bond and hence more stable sister, squalane shows up more often on ingredient lists. Read about squalane here >>
A form of skincare superstar, vitamin C. Even though we are massive vitamin C fans, Ascorbyl Palmitate (AP) is our least favorite. (Btw, if you do not know what the big deal with vitamin C is then you are missing out. You must go and read our geeky details about it.)
So, AP is one of the attempts by the cosmetics industry to solve the stability issues with vitamin C while preserving its benefits, but it seems to fall short on several things.
What's the problem?
Firstly, it's stability is only similar to that of pure ascorbic acid (AA), which means it is not really stable. A great study in the Journal of Cosmetic Dermatology compared a bunch of vitamin C derivatives and this derivative was the only one where the study said in terms of stability that it's "similar to AA". Not really that good.
Second, a study that examined the skin absorption of vitamin C found that ascorbyl palmitate did not increase the skin levels of AA. This does not mean that ascorbyl palmitate cannot penetrate the skin (because it can, it's oil soluble and the skin likes to absorb oil soluble things) but this means that it's questionable if ascorbyl palmitate can be converted into pure Vit C in the skin. Even if it can be converted, the palmitate part of the molecule is more than the half of it, so the efficacy will not be good and we have never seen a serum that contains a decent (and proudly disclosed) amount of AP. We are highly skeptical what effect a tiny amount of AP has in a formula.
Third, another study that wanted to examine the antioxidant properties of AP was surprised to find that even though AP does have nice antioxidant properties; following UVB radiation (the same one that comes from the sun) it also promotes lipid peroxidation and cytotoxicity. It was only an in-vitro study meaning that it was done on cell cultures and not on real people, but still, this also does not support the use of AP too much.
The only good thing we can write about Ascorbyl Palmitate is that there is an in-vitro (made in the lab, not on real people) study showing that it might be able to boost collagen production.
Regarding the skin-brightening properties of pure vitamin C, this is another magic property AP does not have, or at least there is no data, not even in-vitro, about it.
Overall, Ascorbyl Palmitate is our least favorite vitamin C derivative. It is there in lots of products in tiny amounts (honestly, we do not really understand why), however, we do not know about any vitamin C serum featuring AP in high amounts. That is probably no coincidence. If you are into vitamin C, you can take a look at more promising derivatives here.
The emollient plant oil coming from the soybean. It is considered to be a nice, cost-effective base oil with moisturizing properties. As for its fatty acid profile, it contains 48-59% barrier-repairing linoleic acid, 17-30% nourishing oleic acid and also some (4.5-11%) potentially anti-inflammatory linolenic acid.
- It's a helper ingredient that improves the freeze-thaw stability of products
- It's also a solvent, humectant and to some extent a penetration enhancer
- It has a bad reputation among natural cosmetics advocates but cosmetic scientists and toxicology experts do not agree (read more in the geeky details section)
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA.
So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh.
There is also some research showing that citric acid with regular use (think three months and 20% concentration) can help sun-damaged skin, increase skin thickness and some nice hydrating things called glycosaminoglycans in the skin.
But according to a comparative study done in 1995, citric acid has less skin improving magic properties than glycolic or lactic acid. Probably that’s why citric acid is usually not used as an exfoliant but more as a helper ingredient in small amounts to adjust the pH of a formulation.
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
It is typically used in tiny amounts, around 0.1% or less.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.
Also, it's an effective deodorant and a medium spreading emollient.
It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It can be naturally found in fruits and teas but can also be made synthetically.
No matter the origin, in small amounts (up to 1%) it’s a nice, gentle preservative. Has to be combined with some other nice preservatives, like potassium sorbate to be broad spectrum enough.
In high amounts, it can be a skin irritant, but don’t worry, it’s never used in high amounts.
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| what‑it‑does | solvent |
| what‑it‑does | solvent | moisturizer/humectant |
| what‑it‑does | antioxidant | emollient |
| what‑it‑does | emollient |
| what‑it‑does | skin-identical ingredient | emollient |
| irritancy, com. | 0, 1 |
| what‑it‑does | emollient | perfuming |
| irritancy, com. | 0, 4 |
| what‑it‑does | emollient | viscosity controlling | emulsifying | surfactant/cleansing |
| irritancy, com. | 1, 2 |
| what‑it‑does | emollient | emulsifying |
| irritancy, com. | 0, 1-2 |
| what‑it‑does | emollient | emulsifying |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | antioxidant |
| irritancy, com. | 0, 0 |
| what‑it‑does | cell-communicating ingredient | antioxidant | antimicrobial/antibacterial |
| what‑it‑does | emollient |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | soothing |
| irritancy, com. | 0, 0 |
| what‑it‑does | antioxidant | emollient |
| irritancy, com. | 0, 0-3 |
| what‑it‑does | antioxidant | emollient | moisturizer/humectant |
| what‑it‑does | antioxidant | emollient |
| irritancy, com. | 0, 0-2 |
| what‑it‑does | emollient |
| what‑it‑does | surfactant/cleansing | emulsifying |
| what‑it‑does | antioxidant |
| irritancy, com. | 0-3, 0-3 |
| what‑it‑does | skin-identical ingredient | antioxidant | emollient |
| what‑it‑does | antioxidant |
| irritancy, com. | 0, 2 |
| what‑it‑does | emollient | perfuming |
| irritancy, com. | 0, 3 |
| what‑it‑does | moisturizer/humectant | solvent |
| irritancy, com. | 0, 0 |
| what‑it‑does | viscosity controlling |
| what‑it‑does | buffering |
| what‑it‑does | chelating |
| what‑it‑does | preservative |
| what‑it‑does | preservative |
| what‑it‑does | preservative | perfuming | solvent | viscosity controlling |