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NIOD Modulating Glucosides

NIOD
Modulating Glucosides

A calming serum that reduces inflammation as it occurs. Part of the NIOD core regimen, use after CAIS and before MMHC.
Uploaded by: pnewelljr on 26/04/2018

Highlights

#alcohol-free
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Ingredient name what-it-does irr., com. ID-Rating
Aqua (Water) solvent
Squalane skin-identical ingredient, emollient 0, 1 goodie
Isodecyl Neopentanoate emollient
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Caprylic/Capric Triglyceride emollient
Pentylene Glycol solvent, moisturizer/​humectant
Propanediol solvent, moisturizer/​humectant
Hexyldecanol emollient
Bisabolol soothing goodie
Butylene Glycol moisturizer/​humectant, solvent 0, 1
Epigallocatechin Gallatyl Glucoside antioxidant, soothing goodie
Rosmarinyl Glucoside antioxidant, soothing goodie
Caffeyl Glucoside antioxidant, soothing goodie
Gallyl Glucoside antioxidant, soothing goodie
Tetrasodium Tetracarboxymethyl Naringeninchalcone soothing goodie
Hydroxymethoxyphenyl Decanone antioxidant, soothing goodie
4-T-Butylcyclohexanol soothing, cell-communicating ingredient goodie
Cetylhydroxyproline Palmitamide emollient goodie
Hydroxyphenyl Propamidobenzoic Acid soothing goodie
Palmitoyl Tripeptide-8 soothing goodie
Superoxide Dismutase antioxidant goodie
Sodium Pca skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Pca skin-identical ingredient, moisturizer/​humectant goodie
Arginine skin-identical ingredient goodie
Glycine skin-identical ingredient goodie
Alanine skin-identical ingredient goodie
Serine skin-identical ingredient goodie
Valine skin-identical ingredient goodie
Isoleucine skin-identical ingredient goodie
Proline skin-identical ingredient goodie
Threonine skin-identical ingredient goodie
Histidine skin-identical ingredient, moisturizer/​humectant goodie
Phenylalanine skin-identical ingredient goodie
Aspartic Acid skin-identical ingredient goodie
Sodium Lactate buffering, moisturizer/​humectant goodie
Mirabilis Jalapa Callus Extract
Tasmannia Lanceolata Fruit/Leaf Extract antioxidant, soothing goodie
Zingiber Officinale (Ginger) Root Extract antioxidant, soothing goodie
Curculigo Orchioides Root Extract soothing goodie
Isochrysis Galbana Extract
Brassica Campestris (Rapeseed) Sterols emollient
Stearic Acid emollient, viscosity controlling 0, 2-3
Dextran viscosity controlling
Isoceteth-20 emulsifying, surfactant/​cleansing
Polyacrylate Crosspolymer-6 viscosity controlling
Xanthan Gum viscosity controlling
Tocopherol antioxidant 0-3, 0-3 goodie
Propyl Gallate antioxidant, perfuming
Tromethamine buffering
Dehydroacetic Acid preservative
1,2-Hexanediol solvent
Benzyl Alcohol preservative, perfuming, solvent, viscosity controlling
Phenoxyethanol preservative
Caprylyl Glycol moisturizer/​humectant, emollient

NIOD Modulating Glucosides
Ingredients explained

Also-called: Water | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

Squalane - goodie
What-it-does: skin-identical ingredient, emollient | Irritancy: 0 | Comedogenicity: 1

It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated  (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life. 

It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy.

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Another advantage of squalane is that it is pretty much compatible with all skin types and skin conditions. It is excellent for acne-prone skin and safe to use even if you have fungi-related skin issues, like seborrhea or fungal acne.

The unsaturated (with double bonds) and hence less stable version of Squalane is Squalene, you can read about it here >> 

What-it-does: emollient

A  low molecular weight dry, silky emollient ester that gives a light and non-greasy feel to the formulas. It's great at reducing the oily or heavy feeling caused by certain ingredients such as sunscreen agents or pigments. It also gives improved emolliency, spreadability and a smooth, elegant feel on the skin.

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot)
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

What-it-does: emollient

A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, and it’s also easy to formulate with. No wonder it’s popular. 

A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent and a broad spectrum antimicrobial. According to manufacturer info, it's also a moisturizer and helps to make the product feel great on the skin. It works synergistically with preservatives and helps to improve water-resistance of sunscreens. 

Also-called: Zemea | What-it-does: solvent, moisturizer/humectant

Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved. 

It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. 

What-it-does: emollient

A yellowish oily liquid that works as a medium spreading emollient and is suitable for a wide pH range. 

Bisabolol - goodie
Also-called: Alpha-Bisabolol | What-it-does: soothing

It's one of the active parts of Chamomile that contains about 30% of bisabolol. It's a clear oily fluid that is used in skincare as a nice anti-inflammatory and soothing ingredient. 

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

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It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive. 

What-it-does: antioxidant, soothing

It's a "bioengineered" version of superstar green tea polyphenol, EGCG (EGCG attached to a glucose molecule). According to the manufacturer, it's a highly water soluble, stabilized and purified form that's easier to formulate but it keeps the great antioxidant and anti-inflammatory benefits of  regular EGCG. It's  Ecocert approved.

What-it-does: antioxidant, soothing

The water-soluble, stabilized and bio-available version of rosmarinic acid (rosmarinic acid attached to the sugar molecule, glucose), the active super component in Rosemary. It is known for its potent antioxidant and anti-inflammatory properties. 

According to manufacturer's info, it not only inhibits important inflammation pathways, but it also protects important ECM (Extra Cellular Matrix - the gooey stuff between the skin cells) components, such as collagen and hyaluronic acid. Both are done by inhibiting evil enzymes that attack these important skin building blocks, such as famous collagen-destroying enzyme MMP, and HA eating enzyme hyaluronidase. 

What-it-does: antioxidant, soothing

The water-soluble, stabilized, and purified version of the famous antioxidant molecule, caffeic acid (caffeic acid attached to the sugar molecule, glucose), the main phyto-active of green coffee. Caffeyl Glucoside is also claimed to have a strong anti-inflammatory and photoprotective effect.

What-it-does: antioxidant, soothing

Gallyl Glucoside is a glycosylated form of gallic acid (i.e. attaching the sugar molecule, glucose to gallic acid) coming from oak leaves. It is known for its antioxidant and soothing properties and usually comes to the formula combined with other plant-derived glucosides. 

What-it-does: soothing

A water-soluble, stabilized molecule derived from the polyphenol naringenin chalcone, which naturally occurs in the peel of citrus fruits and tomato skin and is known for its potent anti-allergic and anti-inflammatory properties.

According to the Swiss manufacturer's clinical study with 11 people, an emulsion containing 0.1%Tetrasodium Tetracarboxymethyl Naringeninchalcone applied twice daily for 56 days visibly reduces skin redness and improves the signs of rosacea skin

What-it-does: antioxidant, soothing

A nature-identical (but synthetic) molecule that copies a phyto-active found in grains of paradise, a spice from the ginger family. It is claimed to be a 4-in-1 active with potent topical & cellular antioxidant, anti-irritant, and hyaluronic acid booster activity, however, the manufacturer did only some in-vitro and ex-vivo (i.e. nothing done on real people... ) tests to back up these claims.  

Also-called: SymSitive | What-it-does: soothing, cell-communicating ingredient

A soothing molecule whose special feature is to instantly decrease stinging and burning sensations. According to the manufacturer's impressive numbers, it can reduce stinging up to 78% and burning sensation by up to 80% after just 3 minutes. 

It is so effective because it works at a cellular level via intercepting the signals caused by the irritation before they can reach the neuro-receptor. This means that we feel stinging and burning sensations much less and the skin's tolerance threshold is increased

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The effectiveness of SymSitive was also backed up by a comparative study. It found that both 4‐t‐Butylcyclohexanol and fellow cell-communicating, soothing molecule acetyl dipeptide‐1 cetyl ester works, but 4‐t‐Butylcyclohexanol works better.

What-it-does: emollient

A pseudo-ceramide that is similar to Ceramide 2 in structure and activity and is claimed to be a great ingredient for a healthy skin barrier or to repair damaged skin or hair. In general, Ceramides are super important lipids in the outer layer of the skin and we have written some more about them here >> 

Also-called: SymCalmin | What-it-does: soothing

An anti-irritant and anti-itch molecule that copies the active ingredient (Avenanthramides) in the well-known soothing plant, oat. 

According to the manufacturer's clinical study (double-blind, 40 people, 4 weeks long), 2% SymCalmin (the trade name of our diluted - 5% - molecule) reduced itchiness significantly by 65% and it also reduced redness by 50%. 

Also-called: Neutrazen | What-it-does: soothing

We don't have description for this ingredient yet.

Also-called: SOD | What-it-does: antioxidant

Superoxide Dismutase - or in short SOD - is the body's smart antioxidant enzyme that protects the cells from highly reactive, cell-damaging superoxide radicals (O2−).

You have probably read the terms "free radicals" and "antioxidants" a thousand times, and you know that free radicals are the evil guys, and antioxidants are the good guys. So superoxide radical is a very common free radical that can cause all kinds of cell damages and superoxide dismutase is an enzyme that catalyzes the conversion of superoxide radicals into molecular oxygen and hydrogen peroxide (btw, this one has to be further converted by other antioxidant enzymes, called catalases).

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The extra nice thing about SOD is that it remains intact during the neutralization process and can continue its magic, while non-enzymatic antioxidants (like vitamin E) are used up during neutralization.

The efficacy studies of topical SOD are promising. In-vitro (made in the lab) tests show that SOD is a more effective antioxidant than vitamin E, green tea extract, and MAP. There is also an in-vivo (made on real people) study that measured how SOD can reduce the redness caused by UV rays and it was much more effective than vitamin E (pure or acetate form) and ascorbyl palmitate

All in all, SOD is a really potent antioxidant and slathering it all over yourself is a great way to give the skin a little extra help in protecting itself from all the bad environmental things out there. 

Sodium Pca - goodie
What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

PCA stands for Pyrrolidone Carboxylic Acid and though it might not sound like it, it is a thing that can be found naturally in our skin. The sodium salt form of PCA is an important skin-identical ingredient and great natural moisturizer that helps the skin to hold onto water and stay nicely hydrated. 

Pca - goodie
Also-called: Pyrrolidone Carboxylic Acid | What-it-does: skin-identical ingredient, moisturizer/humectant

PCA stands for Pyrrolidone Carboxylic Acid and though it might not sound like it, it is a thing that can be found naturally in our skin. In fact, after amino acids, it is the second biggest NMF component of the skin with 12% being PCA of the NMF composition of normal skin.  So similar to other NMFs, it's a skin goodie that helps the skin to hold onto water and stay nicely hydrated. 

Arginine - goodie

A semi-essential (infants cannot synthesize it, but adults can) amino acid that is one of the primary building blocks of hair keratin and skin collagen. It's a natural moisturizing factor, a skin hydrator and might also help to speed up wound healing

Arginine usually has a positive charge (cationic) that makes it substantive to skin and hair (those are more negatively charged surfaces) and an excellent film former.  Thanks to the positive charge, it also creates a complex with AHAs (AHAs like to lose a hydrogen ion and be negatively charged, so the positive and the negative ions attract each other) that causes a "time-release AHA effect" and reduces the irritation associated with AHAs

Glycine - goodie

A non-essential amino acid (the building blocks of skin proteins, like collagen or elastin), that the body can produce itself, but its production decreases with age. When you put it all over your face, it works as a moisturizer and maybe more. 

According to great skincare blog Futurederm, glycine might help with wound healing and tissue repair and when used together with other amino acids, leucine and proline it might improve wrinkles

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BTW, it's also a building block of a bunch of important and famous peptides, including copper-tripeptide-1, palmitoyl tripeptide-1 or palmitoyl hexapeptide-12.

Alanine - goodie

A non-essential amino acid (a building block of skin proteins like collagen or elastin) that hydrates the skin.

Serine - goodie

Serine is an amino acid that most often comes to the formula as part of a moisturizing complex. It's a non-essential amino acid (meaning that our body can synthesize it) and serves as a water-binding ingredient.

In general, amino acids are great skincare ingredients that play an important role in proper skin hydration but there is not much info out there about what specifically serine can do for the skin.

Valine - goodie

An essential amino acid (a building block of skin proteins like collagen) that our body cannot produce itself but has to take from external sources, like diet. 

It's a branched chain amino acid that is claimed to enhance energy, increase endurance and aid in muscle tissue recovery and repair when taken as a supplement. It's not clear what valine does when you put it on the skin, but as all amino acids, it must be at least a great skin hydrator.

Isoleucine - goodie

A branch-chained, essential amino acid that can be found in things like almond, cashew or soy protein. When taken orally it may promote protein synthesis. As for skincare - like all the amino acids - it's a skin-identical ingredient and moisturizer. It also seems to be useful as a barrier repair ingredient.  

Proline - goodie

A non-essential amino acid (meaning that our body can produce it) that's also one of the major building blocks of collagen. According to the Futurederm blog, it might be able to improve wrinkles when combined with other amino acids, glycine and leucine

Threonine - goodie

An essential amino acid that's also a key building block of collagen and elastin. When taken orally, it helps the digestive and intestinal tracts function more smoothly and also helps the absorption of nutrients. As for skincare, it is not clear what it does other than being a skin hydrator

Histidine - goodie

A semi-essential amino acid meaning that enough has to be eaten from it so that the body does not use up essential amino acids (that our body cannot produce itself) to synthesize it. It has an important role in regulating the immune defense, allergic reactions, and inflammatory processes in the body.

As for skincare, it's a skin moisturizer that might also protect from some skin infections

Phenylalanine - goodie

An essential amino acid that the body cannot produce itself but has to take from the diet. Combined with UVA exposure, phenylalanine is used in the treatment of vitiligo (a pigmentation disorder where patches of the skin lose the pigment).

Aspartic Acid - goodie

A non-essential amino acid  (important building block of collagen and elastin) that hydrates the skin. It is also used to set the pH of the cosmetic product (buffering).

The sodium salt of lactic acid. It's a great skin moisturizer and also used to regulate the pH value of the cosmetic formula. It's a natural ingredient approved by both ECOCERT and COSMOS.

We don't have description for this ingredient yet.

Also-called: Tasmanian Pepper Extract | What-it-does: antioxidant, soothing

Tasmanian Pepper is a nice shrub living under hard conditions in the mountains of the Southeastern lands of Australia. It has small, round, purple-black berries that when dried, look like black pepper. Hence the name. 

As for skincare, the berries contain a couple of great actives. The primary one is called polygodial that has potent anti-inflammatory, anti-allergic and antimicrobial activity. According to the manufacturers in-vivo (made on real people) tests, Tasmanian Pepper Extract can relieve itching and burning sensation to a great extent (79% and 58% decrease) almost instantly (after only 5 mins).

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It also contains anthocyanins, that are well-known antioxidants. The berries are claimed to have an antioxidant power 3x greater than blueberries. A third active in the berries is called rutin, an anti-inflammatory agent that can strengthen capillaries. Thanks to this, Tasmanian Pepper might be able to help reduce dark undereye circles

All in all, an interesting plant extract with soothing and antioxidant activity.

Also-called: Ginger Root Extract | What-it-does: antioxidant, soothing

The extract coming from ginger, the lovely spice that we all know from the kitchen. It is also a medicinal plant used both in Chinese and Ayurvedic medicine for pretty much everything you can imagine (muscular pain, sore throat, nausea, fever or cramps,  just to give a few examples).

As for ginger and skincare, the root extract contains the biologically active component called gingerol that has potent antioxidant and anti-inflammatory properties. Combined with Bisabololthe duo works synergistically to sooth the skin and take down redness. 

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Other than that, ginger also contains moisturizing polysaccharides, amino acids, and sugars, and it is also quite well known to increase blood circulation and have a toning effect.

Last but not least, Ginger also has some volatile, essential oil compounds (1-3%). Those are mostly present in ginger oil, but small amounts might be in the extract as well (around 0.5% based on manufacturer info). 

Also-called: Curculigo Root Extract, Golden Eye-Grass Root Extract | What-it-does: soothing

A plant extract coming from a nice yellow flower from the shady forests of Asia. It's a traditional medicinal plant with a bunch of magic properties: it's claimed to be aphrodisiac, anti-inflammatory, sedative, antioxidant, hepatoprotective, and even anticancer. 

As for skincare, the root extract is loaded with sugars and a phenolic glycoside called curculigosides. According to manufacturer info, Golden Eye-Grass can modulate the internal mechanism of skin's pH control. The right pH of the skin (slightly acidic SC) is really important for lipid-processing enzymes to work correctly and thus to maintain a strong and healthy skin barrier. And a good skin barrier means less sensitive, less reactive and more healthy skin

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Definitely an interesting plant and goodie if you have sensitive skin. 

We don't have description for this ingredient yet.

What-it-does: emollient

We don't have description for this ingredient yet.

What-it-does: emollient, viscosity controlling | Irritancy: 0 | Comedogenicity: 2-3

A common multi-tasker fatty acid. It makes your skin feel nice and smooth (emollient), gives body to cream type products and helps to stabilize water and oil mixes (aka emulsions).

What-it-does: viscosity controlling

We don't have description for this ingredient yet.

A handy helper ingredient that works as an emulsifier or solubilizer to include oil-loving ingredients (such as fragrance) into water-based products. 

What-it-does: viscosity controlling

It's a helper ingredient that helps to thicken up formulas and form a nice gel texture. It leaves a rich, elegant feel with a velvety finish on the skin and works over a wide pH range.

It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little of xanthan gum will make it more gel-like.  Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). 

Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415). 

Tocopherol - goodie
Also-called: Vitamin E | What-it-does: antioxidant | Irritancy: 0-3 | Comedogenicity: 0-3
  • Primary fat-soluble antioxidant in our skin
  • Significant photoprotection against UVB rays
  • Vit C + Vit E work in synergy and provide great photoprotection
  • Has emollient properties
  • Easy to formulate, stable and relatively inexpensive
Read all the geeky details about Tocopherol here >>

What-it-does: antioxidant, perfuming

We don't have description for this ingredient yet.

What-it-does: buffering

It's a little helper ingredient that helps to set the pH of the products to be right. It has an alkaline pH and can neutralize acidic ingredients.

Also-called: Geogard 111A | What-it-does: preservative

A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi and has only milder effect against bacteria. 

It is Ecocert and Cosmos approved, works quite well at low concentrations (0.1-0.6%) and is popular in natural products.

What-it-does: solvent

A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives

It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It can be naturally found in fruits and teas but can also be made synthetically.

No matter the origin, in small amounts (up to 1%) it’s a nice, gentle preservative. Has to be combined with some other nice preservatives, like potassium sorbate to be broad spectrum enough.  

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In high amounts, it can be a skin irritant, but don’t worry, it’s never used in high amounts.

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

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Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10). 

It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.

It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol

The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does skin-identical ingredient | emollient
irritancy, com. 0, 1
An emollient and natural moisturizer that can be found also in the sebum (oily stuff our skin produces). It leaves a nice non-greasy, non-heavy feeling on the skin. [more]
what‑it‑does emollient
A  low molecular weight dry, silky emollient ester that gives a light and non-greasy feel to the formulas. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
what‑it‑does emollient
A very common emollient that makes your skin feel nice and smooth. Comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. [more]
what‑it‑does solvent | moisturizer/humectant
A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent, and a broad spectrum antimicrobial. [more]
what‑it‑does solvent | moisturizer/humectant
A natural corn sugar derived glycol. It can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. [more]
what‑it‑does emollient
A yellowish oily liquid that works as a medium spreading emollient and is suitable for a wide pH range.  [more]
what‑it‑does soothing
One of the active parts of Chamomile that is used in skincare as a nice anti-inflammatory and soothing ingredient. [more]
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0, 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
what‑it‑does antioxidant | soothing
A bioengineered version of superstar green tea polyphenol, EGCG. It's claimed to be a stabilized and purified form that keeps the great antioxidant and anti-inflammatory benefits of regular EGCG. [more]
what‑it‑does antioxidant | soothing
The bioengineered version of rosmarinic acid, the potent antioxidant, and anti-inflammatory active in Rosemary. [more]
what‑it‑does antioxidant | soothing
The derivative of the antioxidant caffeic acid, the phyto-active of green coffee. It is also thought to be a strong anti-inflammatory and photoprotective. [more]
what‑it‑does antioxidant | soothing
Gallyl Glucoside is a glycosylated form of gallic acid (i.e. attaching the sugar molecule, glucose to gallic acid) coming from oak leaves. It is known for its antioxidant and soothing properties and usually comes to the formula combined with other plant-derived glucosides.  [more]
what‑it‑does soothing
A water-soluble, stabilized molecule derived from the polyphenol naringenin chalcone, which naturally occurs in the peel of citrus fruits and tomato skin and is known for its potent anti-allergic and anti-inflammatory properties.According to the Swiss manufacturer's clinical study with 11 people, an emulsion containing 0. [more]
what‑it‑does antioxidant | soothing
A nature-identical (but synthetic) molecule that copies a phyto-active found in grains of paradise, a spice from the ginger family. It is claimed to be a 4-in-1 active with potent topical & [more]
what‑it‑does soothing | cell-communicating ingredient
A soothing molecule whose special feature is to instantly decrease stinging and burning sensations. According to the manufacturer's impressive numbers, it can reduce stinging up to 78% and burning sensation by up to 80% after just 3 minutes. It is so effective because it works at a cellular level  [more]
what‑it‑does emollient
A pseudo-ceramide that is similar to Ceramide 2 in structure and activity and is claimed to be a great ingredient for a healthy skin barrier or to repair damaged skin or hair.  [more]
what‑it‑does soothing
An anti-irritant and anti-itch molecule that copies the active ingredient in the well-known soothing plant, oat.  [more]
what‑it‑does soothing
what‑it‑does antioxidant
Superoxide Dismutase - or in short SOD - is the body's smart antioxidant enzyme that protects the cells from highly reactive, cell-damaging superoxide radicals (O2−). You have probably read the terms "free radicals" [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
It's an important skin-identical ingredient and great natural moisturizer that helps the skin to hold onto water and stay nicely hydrated. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
PCA stands for Pyrrolidone Carboxylic Acid and though it might not sound like it, it is a thing that can be found naturally in our skin. In fact, after amino acids, it is the second biggest NMF component of the skin with 12% being PCA of the NMF composition of normal skin.  So similar to other NMFs, it's a skin goodie that  [more]
what‑it‑does skin-identical ingredient
An amino acid that is one of the primary building blocks of hair keratin and skin collagen. It's a natural moisturizing factor and might also help to speed up wound healing.  [more]
what‑it‑does skin-identical ingredient
An amino acid (the building blocks of skin proteins, like collagen) that hydrates the skin and might help wound healing and improve wrinkles. [more]
what‑it‑does skin-identical ingredient
A non-essential amino acid (a building block of skin proteins like collagen or elastin) that hydrates the skin.
what‑it‑does skin-identical ingredient
Serine is an amino acid that most often comes to the formula as part of a moisturizing complex. It's a non-essential amino acid (meaning that our body can synthesize it) and serves as a water-binding ingredient.In general, amino acids are great skincare ingredients that play an important role in proper skin hydration but there is not much info out there about what specifically serine can d [more]
what‑it‑does skin-identical ingredient
An essential amino acid (a building block of skin proteins like collagen) that is a skin hydrator. [more]
what‑it‑does skin-identical ingredient
An essential amino acid that hydrates the skin and might be also a barrier repair ingredient. [more]
what‑it‑does skin-identical ingredient
A non-essential amino acid (meaning that our body can produce it) that might be able to improve wrinkles combined with other amino acids, glycine and leucine. [more]
what‑it‑does skin-identical ingredient
An essential amino acid (important building block of collagen and elastin) that hydrates the skin. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
An amino acid that is important in regulating the immune defense and inflammatory processes in the body. It's a skin moisturizer that might protect from skin infections. [more]
what‑it‑does skin-identical ingredient
An essential amino acid that is used in the treatment of vitiligo. [more]
what‑it‑does skin-identical ingredient
A non-essential amino acid  (important building block of collagen and elastin) that hydrates the skin. [more]
what‑it‑does buffering | moisturizer/humectant
The sodium salt of lactic acid. It's a great skin moisturizer and also used to regulate the pH value of the cosmetic formula. [more]
what‑it‑does antioxidant | soothing
Tasmanian Pepper Extract that has anti-inflammatory, anti-allergenic and antioxidant activity. It's great at relieving itching and burning sensation. [more]
what‑it‑does antioxidant | soothing
Ginger extract that has antioxidant and soothing properties. It is also known to increase blood circulation and thus have a toning effect. [more]
what‑it‑does soothing
A traditional medicinal plant loaded with sugars and a phenolic glycoside called curculigosides. It's claimed to be able to modulate the internal mechanism of skin's pH control that results in better skin barrier and in less sensitive skin. [more]
what‑it‑does emollient
what‑it‑does emollient | viscosity controlling
irritancy, com. 0, 2-3
A common multi-tasker fatty acid that works as an emollient, thickener and emulsion stabilizer. [more]
what‑it‑does viscosity controlling
what‑it‑does emulsifying | surfactant/cleansing
A handy helper ingredient that works as an emulsifier or solubilizer to include oil-loving ingredients (such as fragrance) into water-based products. 
what‑it‑does viscosity controlling
A helper ingredient that helps to thicken up formulas and form a nice gel texture. It leaves a rich, elegant feel with a velvety finish on the skin.
what‑it‑does viscosity controlling
A super commonly used thickener and emulsion stabilizer. [more]
what‑it‑does antioxidant
irritancy, com. 0-3, 0-3
Pure Vitamin E. Great antioxidant that gives significant photoprotection against UVB rays. Works in synergy with Vitamin C. [more]
what‑it‑does antioxidant | perfuming
what‑it‑does buffering
It's a little helper ingredient that helps to set the pH of the products to be right. It has an alkaline pH and can neutralize acidic ingredients.
what‑it‑does preservative
A preservative that works mainly against fungi and has only milder effect against bacteria. Popular in natural products.  [more]
what‑it‑does solvent
A multi-functional helper ingredient that acts as a humectant and emollient. It's also a solvent and can boost the effectiveness of preservatives. [more]
what‑it‑does preservative | perfuming | solvent | viscosity controlling
It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It can be naturally found in fruits and teas but can also be made synthetically. No matter the origin, in small amounts (up to 1%) it’s a nice, gentle preservative. [more]
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
what‑it‑does moisturizer/humectant | emollient
A handy multi-tasking ingredient that gives the skin a nice, soft feel and also boosts the effectiveness of other preservatives. [more]