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Acetyl Dipeptide-1 Cetyl Ester

Also-called-like-this: Calmosensine


 A soothing dipeptide (tyrosine + arginine) based molecule that functions as a "messenger of tranquility and muscle relaxation". It works via stimulating the skin nerve cells to release met-enkephalin, which is an opioid (i.e. relaxing, pain-relieving) messenger molecule. 

This means that Acetyl Dipeptide-1 Cetyl Ester can "signal" our skin cells to "relax" and it can instantly decrease skin irritations coming from heat, chemical stinging or mechanical stresses. It is also claimed to be able to prevent the onset of wrinkles and expression lines thanks to its muscle relaxation properties.

Regarding the research, we could find one study that compared the calming effects of our guy with the soothing molecule called 4-T-Butylcyclohexanol. They irritated the skin with Capsaicin (the active in chili peppers) and examined how the test products relieved the burning/stinging sensation. They found that both molecules worked, but 4-t-Butylcyclohexanol worked somewhat better. 

Show me some proof

  • Schoelermann, A. M., et al. "Comparison of skin calming effects of cosmetic products containing 4‐t‐butylcyclohexanol or acetyl dipeptide‐1 cetyl ester on capsaicin‐induced facial stinging in volunteers with sensitive skin." Journal of the European Academy of Dermatology and Venereology 30.S1 (2016): 18-20.

Products with Acetyl Dipeptide-1 Cetyl Ester

Marcelle Newage 8-In-1 Power Serum Beverly Hills MD Lift + Firm Sculpting Cream HSBCC Neck Firming Cream Stripped Calm Down For Face Ecoforia Aqua Moist Leave-In Conditioning Spray Ahava Beauty Before Age Uplift Night Cream Ecoforia Keratin Repair Conditioner Ecoforia Loss Control Conditioner Ecoforia Loss Control Scalp Mask Ecoforia Volume Maker Conditioner Gundry MD Polyphenol Firm + Sculpt Cream Karine Joncas Collagen SN-8 Sesderma Acnises Tea Tree Peel-Off Mask Sesderma Salises Charcoal Peel-Off Mask Skoah. Kontrol Serum Ahava Beauty Before Age Uplift Day Cream Spf20 Ecoforia Aqua Moist Shampoo Ecoforia Color Protect Conditioner Ecoforia Color Protect Shampoo Ecoforia Keratin Repair Shampoo Ecoforia Loss Control Shampoo Ecoforia Volume Maker Shampoo Farmona Herbal Care Siberian Iris Founder's Formula Centipeda Australian Clay Mask Glymed Plus Daily Lift Serum L'Oreal Revitalift Laser X3 Triple Action Cream Mask Ecoforia 3-Phase Recovery Face Elixir Ecoforia Aqua Moist Conditioner Ecoforia Keratin Repair 15 in 1 Leave-In Cream ISOMERS Skincare Shave Cream & Cleanser Optaderm Integrity Facial Lotion Perlier Black Rice Multi Peptide Concentrate Prai Ageless Eye Tight Uplift Serum Absolute Care Vitamin A & E Retinol Face Serum Cellular Skin Rx Stress Recovery Complex Ecoforia Duo Retreat Eye Cream Ecoforia Glow Infusion Peel-Off Face Mask Ecoforia Keratin Repair Hair Mask Ecoforia Lamellar Relax Night Face Cream Founder's Formula Post-workout Australian Clay Detox Mask For Clear Skin - With Muslin Cleansing Cloth L'Oreal Revitalift Laser Pressed-cream night L'Oreal Revitalift Laser Retinol + Niacinamide Pressed Night Cream L'Oreal Paris Revitalift Derm Intensives Vitamin C + Vitamin E+ Salicylic Acid Serum Optaderm Serenity Facial Serum Plush Bio Triple Hyal 23H Ecoforia Color Protect Hair Mask Ecoforia Lamellar Illuminating Day Face Cream Farmona Professional Anti Pollution Revitalizing And Refreshing Eye Roll-On Cream L'Oreal Revitalift Yaşlanma Karşıtı Hızlı Etki Serumu La Roche-Posay Toleriane Ultra Dermallergo Sheet Mask