Hyalogy Β
Ingredients overview
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Key Ingredients
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Forlle'd Hyalogy ΒIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.
BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.
It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive.
A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives.
We don't have description for this ingredient yet.
If you see a cosmetic product that claims that it has "Botox-like effect" then two things are almost certain: one, the product overpromises and two, it contains Argireline.
So this one is the famous peptide that's marketed by its manufacturer as the "Botox in a jar". The basis for this claim is that it targets the same wrinkle forming mechanism (wrinkles caused by facial muscle movement) as Botox, but the way it works is very different. In addition, the extent to which it can prevent muscles from contracting (and to smooth wrinkles) is very different (otherwise why would anyone use still Botox?).
The manufacturer did several studies to prove that Argireline really works and it does (just not as well as Botox). In-vivo (made on real people) tests showed that using 10% Argireline solution around the eyes for 15 days decreased wrinkles depth by 17%, while a 5% Argireline formula applied for 28 days did almost the same with a decrease in wrinkle depth by 16.26%. A Spanish University also did some research and found that Argireline increased the level of skin moisturization and decreased both the depth and width of wrinkles "significantly".
This means, Acetyl Hexapeptide-8 does have some ability to smooth wrinkles (but not as well as Botox - sorry, if we sound like a broken record). Also, we have to agree with TruthInAging, that it's not a collagen builder and not a preventer of structural aging (think vitamin C, AHAs or retinol); it's just a quick fix. If you are looking for one, this could be your thing. If you are more of a "let's treat this aging thing properly" type, then it's probably not your thing.
This awfully long named ingredient is, in fact, a pretty small molecule. It's a tripeptide (a three amino acid peptide) with molecular weight less than 500 Da, meaning that it's small enough to penetrate nicely and easily into the skin.
It belongs to the "Botox in a jar" type of peptides (similar to Argireline or Leuphasyl) targeting wrinkles caused by facial movements, like laughter lines or crow’s feet. According to the manufacturer's in-vivo (made on real people) studies, 4% Syn-Ake used for 28 days resulted in 21% smoother and 15-20% less wrinkled skin with max values up to 52%. The smoothing effect was measurable on 80% of the volunteers, while the wrinkle reduction effect was evident on 73%.
A pretty famous and better-researched peptide consisting of five amino acids (the building blocks of all proteins). It was created in a joint effort by the French ingredient supplier, Sederma and the cosmetics industry big shot, Procter&Gamble.
The amino acid sequence of the peptide is lysine–threonine–threonine–lysine–serine (KTTKS). Sometimes, it's also called collagen pentapeptide, as it's a subfragment of skin-structure-giving type I collagen. The KTTKS amino sequence is then attached for better oil solubility and skin penetration to palmitic acid and BOOM; we get Palmitoyl Pentapeptide-4.
Though most research is manufacturer sponsored, the clinical studies about Palmitoyl Pentapeptide-4 are promising. In short, it can reduce fine lines, wrinkles and improve skin texture significantly (and at crazy low concentrations, the studies were done with just 3 ppm that is 0.0003%).
There are also studies comparing Palmitoyl Pentapeptide-4 with anti-aging gold standard, retinol. One of them compared 3ppm Pal-KTTKS with 700 ppm (0.07%) retinol and found that they showed similar wrinkle improving ability with the peptide showing better skin tolerability.
Bottom line, if you are into peptides, this is a good one to try.
Thanks to Nivea, Q10 is a pretty well-known ingredient and the fame and Beiersdorf's (the parent company of Nivea) obsession with it are not for no reason. It's an antioxidant found naturally in human cells where it plays a big role in energy production.
In fact, it's so important for energy production that if taken as an oral supplement it has a caffeine-like effect and if taken at night you will probably not sleep very well (so you should take it in the morning). Q10 supplementation is not a bad idea: it not only gives you energy but research also shows that oral Q10 increases the Q10 level of the skin (of course, it decreases with age like pretty much every good thing in the skin) and may help to reduce wrinkles. If you are not for supplements, dietary sources include fish, spinach, and nuts.
As for skincare, Q10 comes in the form of a yellow, oil-soluble powder that's shown to absorb into the upper layer of the skin and act there like an awesome antioxidant. It not only has preventative effects but might also be able to reduce the depth of wrinkles, though 0.3% Q10 was used in the study that counts as really high (products containing that much should be very yellow!).
It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.
As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution".
In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).
What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists.
If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
If you are fighting acne and have looked into oral supplements, chances are that zinc gluconate sounds familiar to you. It is a zinc salt that has research proving it to be effective against inflammatory acne, though not quite as effective as the antibiotic minocycline (31.2% vs. 63.4% success rate). However, zinc supplements are easily available, have little-to-no side effects, so supplementing them with a 30mg per day dose can still be a good idea.
As for smearing zinc gluconate all over your face, it is also not a bad idea. Zinc has multiple magic abilities: it is antibacterial (including evil, acne-causing P. acnes) and sebum-regulating (5α-reductase inhibitor), great for acne-prone skin types. It also stimulates antioxidant enzyme systems (mainly superoxide dismutase) and has nice wound healing abilities acting mainly in the first, proliferation phase. So great for skin types in need of healing and soothing.
What about the gluconate part? It is there to promote the absorption and bioavailability of zinc and also plays a role in cellular regeneration (involved in the synthesis of ribose sugars, structural components of DNA and RNA).
We don't have description for this ingredient yet.
It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life.
It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy.
Another advantage of squalane is that it is pretty much compatible with all skin types and skin conditions. It is excellent for acne-prone skin and safe to use even if you have fungi-related skin issues, like seborrhea or fungal acne.
The unsaturated (with double bonds) and hence less stable version of Squalane is Squalene, you can read about it here >>
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula.
The salt form of one of the main anti-inflammatory ingredients in the licorice plant, monoammonium glycyrrhizinate. It’s a yellowish powder with a nice sweet smell.
It’s used mainly for its soothing and anti-inflammatory properties, but according to manufacturer info, it’s also sebum regulating so it's a perfect ingredient for problem skin products.
Read more about licorice and why it's a skincare superstar here.
You might know licorice as a sweet treat from your childhood, but it's actually a legume that grows around the Mediterranean Sea, the Middle East, central and southern Russia. It's sweet and yellow and not only used for licorice all sorts but it's also a skincare superstar thanks to two magic properties:
Nr. 1 magic property is that it has skin-lightening or to say it another way depigmenting properties. The most active part is called glabridin. The topical application (meaning when you put it on your face) of 0.5% glabridin was shown to inhibit UVB caused pigmentation of guinea pigs. Another study even suggested that licorice is more effective than the gold standard skin-lightening agent hydroquinone. All in all, licorice is considered to be one of the safest skin lightening agents with the fewest side effects.
There is just one catch regarding glabridin and licorice: the amount of glabridin in commercial licorice extracts can vary a lot. We have seen extracts with only 4% glabridin as well as 40% glabridin. The latter one is a very-very expensive ingredient, so if you are after the depigmenting properties try to choose a product that boasts its high-quality licorice extract.
Nr. 2 magic property is that licorice is a potent anti-inflammatory. Glabridin has also some soothing properties but the main active anti-inflammatory component is glycyrrhizin. It’s used to treat several skin diseases that are connected to inflammation including atopic dermatitis, rosacea or eczema.
Oh, and one more thing: glabridin seems to be also an antioxidant, which is just one more reason to be happy about licorice root extract on an ingredient list.
Bottom line: Licorice is a great skincare ingredient with significant depigmenting, anti-inflammatory and even some antioxidant properties. Be happy if it's on the ingredient list. :)
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
Sodium chloride is the fancy name of salt. Normal, everyday table salt.
If (similar to us) you are in the weird habit of reading the label on your shower gel while taking a shower, you might have noticed that sodium chloride is almost always on the ingredient list. The reason for this is that salt acts as a fantastic thickener in cleansing formulas created with ionic cleansing agents (aka surfactants) such as Sodium Laureth Sulfate. A couple of percents (typically 1-3%) turns a runny surfactant solution into a nice gel texture.
If you are into chemistry (if not, we understand, just skip this paragraph), the reason is that electrolytes (you know, the Na+ and Cl- ions) screen the electrostatic repulsion between the head groups of ionic surfactants and thus support the formation of long shaped micelles (instead of spherical ones) that entangle like spaghetti, and viola, a gel is formed. However, too much of it causes the phenomenon called "salting out", and the surfactant solution goes runny again.
Other than that, salt also works as an emulsion stabilizer in water-in-oil emulsions, that is when water droplets are dispersed in the outer oil (or silicone) phase. And last but not least, when salt is right at the first spot of the ingredient list (and is not dissolved), the product is usually a body scrub where salt is the physical exfoliating agent.
A kind of salt that's used as a thickener in cosmetic products.
A copper salt (copper cation + gluconate anion) probably best known for promoting cellular regeneration and wound healing. It works mainly in the final healing phase that complements nicely with the wound healing abilities of its mineral salt sister, zinc gluconate.
Other than that, copper is also involved in several enzyme systems: it is a cofactor for the antioxidant enzyme, superoxide dismutase and also a cofactor for the melanin stimulating enzyme, tyrosinase. This means that copper has some tan activating properties, though we think you should not be into tanning at all, as UV is so bad for the skin.
The gluconate part is there to promote the bioavailability of copper and it also plays a role in cellular regeneration (involved in the synthesis of ribose sugars, structural components of DNA and RNA).
Malic acid comes from apple and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA.
So malic acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh.
There is not much research out there about malic acid itself. We could find one comparative study, that compared the effectiveness of glycolic acid, lactic acid, citric acid and malic acid. The first two ones were the winners while malic and citric acid were less effective.
A sugar beet-derived amino acid derivative with nice skin protection and moisturization properties. Betaine's special thing is being an osmolyte, a molecule that helps to control cell-water balance. It is also a natural osmoprotectant, meaning that it attracts water away from the protein surface and thus protects them from denaturation and increases their thermodynamic stability.
It also gives sensorial benefits to the formula and when used in cleansers, it helps to make them milder and gentler.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
A light-feeling, volatile (meaning it does not absorb into the skin but evaporates from it) silicone that gives skin a unique, silky and non-greasy feel. It has excellent spreading properties and leaves no oily residue or build-up.
A super commonly used 5 unit long, cyclic structured silicone that is water-thin and does not stay on the skin but evaporates from it (called volatile silicone). Similar to other silicones, it gives skin and hair a silky, smooth feel.
It's often combined with the non-volatile (i.e. stays on the skin) dimethicone as the two together form a water-resistant, breathable protective barrier on the skin without a negative tacky feel.
Triethylhexanoin is a colorless to pale yellow liquid ester that makes the skin nice and smooth, aka emollient. It has a pleasant non-sticky, non-greasy feel to it, gives formulas smooth application properties and also helps moisture retention.
A castor oil derived, white, lard-like helper ingredient that is used as a solubilizer to put fragrances (those are oil loving things) into water-based products such as toners.
A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula. It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent and a broad spectrum antimicrobial. According to manufacturer info, it's also a moisturizer and helps to make the product feel great on the skin. It works synergistically with preservatives and helps to improve water-resistance of sunscreens.
It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol.
The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.
It's a very alkaline stuff that helps to set the pH of the cosmetic formula to be just right. It's similar to the more often used sodium hydroxide and pretty much the same of what we wrote there applies here too.
The sodium salt of lactic acid. It's a great skin moisturizer and also used to regulate the pH value of the cosmetic formula. It's a natural ingredient approved by both ECOCERT and COSMOS.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
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| what‑it‑does | solvent |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | moisturizer/humectant | solvent |
| irritancy, com. | 0, 1 |
| what‑it‑does | solvent |
| what‑it‑does | cell-communicating ingredient | moisturizer/humectant |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | antioxidant |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | anti-acne | soothing |
| what‑it‑does | skin-identical ingredient | emollient |
| irritancy, com. | 0, 1 |
| what‑it‑does | emulsifying | surfactant/cleansing |
| irritancy, com. | 0, 0 |
| what‑it‑does | soothing | moisturizer/humectant |
| what‑it‑does | soothing | skin brightening |
| what‑it‑does | viscosity controlling |
| what‑it‑does | viscosity controlling |
| what‑it‑does | viscosity controlling |
| what‑it‑does | soothing |
| what‑it‑does | viscosity controlling |
| what‑it‑does | viscosity controlling |
| what‑it‑does | soothing |
| what‑it‑does | exfoliant | buffering |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | solvent |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | emollient | solvent |
| what‑it‑does | emollient | solvent |
| what‑it‑does | emollient | perfuming |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | viscosity controlling |
| irritancy, com. | 0, 1 |
| what‑it‑does | viscosity controlling |
| what‑it‑does | solvent | moisturizer/humectant |
| what‑it‑does | moisturizer/humectant | emollient |
| what‑it‑does | buffering |
| what‑it‑does | buffering | moisturizer/humectant |
| what‑it‑does | preservative |