Retinol Peptide Lifting Pad
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Dermal Retinol Peptide Lifting PadIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
A clear, colorless liquid that works as a solvent and viscosity decreasing ingredient. It also has great skin-moisturizing abilities.
It's a nice glycerin-based humectant and emollient that gives skin a smooth and luxurious feel.
A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives.
A sugar beet-derived amino acid derivative with nice skin protection and moisturization properties. Betaine's special thing is being an osmolyte, a molecule that helps to control cell-water balance. It is also a natural osmoprotectant, meaning that it attracts water away from the protein surface and thus protects them from denaturation and increases their thermodynamic stability.
It also gives sensorial benefits to the formula and when used in cleansers, it helps to make them milder and gentler.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
Triethylhexanoin is a colorless to pale yellow liquid ester that makes the skin nice and smooth, aka emollient. It has a pleasant non-sticky, non-greasy feel to it, gives formulas smooth application properties and also helps moisture retention.
A spherical texturizing powder that's used as a texture enhancer and soft focus agent. It's claimed to give silicone type softness to the formula and also works as a (temporary) wrinkle filler.
We don't have description for this ingredient yet.
A cellulose (the big molecule found in the cell wall of green plants) derivative that is used as an emulsion stabilizer and thickener.
We don't have description for this ingredient yet.
Super common soothing ingredient. It can be found naturally in the roots & leaves of the comfrey plant, but more often than not what's in the cosmetic products is produced synthetically.
It's not only soothing but it' also skin-softening and protecting and can promote wound healing.
A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula. It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.
A semi-essential (infants cannot synthesize it, but adults can) amino acid that is one of the primary building blocks of hair keratin and skin collagen. It's a natural moisturizing factor, a skin hydrator and might also help to speed up wound healing.
Arginine usually has a positive charge (cationic) that makes it substantive to skin and hair (those are more negatively charged surfaces) and an excellent film former. Thanks to the positive charge, it also creates a complex with AHAs (AHAs like to lose a hydrogen ion and be negatively charged, so the positive and the negative ions attract each other) that causes a "time-release AHA effect" and reduces the irritation associated with AHAs.
Adenosine is an important little compound in our body that has a vital cell-signalling role. Research on smearing it on our face is also promising and shows so far a couple of things:
- It can help with wound healing
- It’s a good anti-inflammatory agent
- It might even help with skin’s own collagen production and improve skin firmness and elasticity
- It helps with barrier repair and protection
- It might be even useful for the hair helping with hair thickness and hair growth
If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.
Also, it's an effective deodorant and a medium spreading emollient.
It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol.
The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.
We don't have description for this ingredient yet.
A glycerin-derived gentle cleansing agent that is described as being skin and eye-friendly, and not leaving the skin dry or tight. It's also used as a co-emulsifier or solubilizer that helps to blend small amounts of oily things into water-based products.
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
It is typically used in tiny amounts, around 0.1% or less.
Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.
BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.
It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive.
At first glance, you could think that Bakuchiol is your average plant extract. It is derived from the seeds of Psoralea Corylifolia, aka Babchi, a plant important in Indian and Chinese medicine. The molecule was first isolated in 1973 and several anti-something properties are known about it: it has anti-inflammatory, antioxidant, anti-tumor, anti-bacterial and hepatoprotective magical abilities like plenty of other Ayurvedic plant extracts.
What makes Bakuchiol a special snowflake is the recent discovery that it behaves on the skin in a way very similar to well-known skincare superstar, retinol. While chemically, it has nothing to do with the vitamin-A family, aka retinoids, comparative gene expression profiling (a fancy way of saying that they compared how retinol and bakuchiol modify the way skin cells behave and produce important skin proteins such as collagen) shows that retinol and bakuchiol regulate skin cell behavior in a similar way.
To be more specific, both Bakuchiol and retinol upregulate collagen I, III and IV production and downregulate MMP, the evil collagen attacking enzyme in our skin. This means more collagen stays in our skin and we all know that more collagen equals firmer, more wrinkle-free skin. A 12-week clinical study using a 0.5% Bakuchiol formula with 17 people using it twice a day confirmed a significant improvement in lines and wrinkles, elasticity, firmness and an overall reduction in photo-damage. Also, the test formula was very well tolerated, without any retinol-like side effects.
What's more, a 2018 double-blind study with 44 people compared 0.5% Bakuchiol with 0.5% retinol cream and found that "bakuchiol is comparable to retinol in its ability to improve photoaging and is better tolerated than retinol". A super promising result after 12 weeks.
If you are not a daredevil-type who doesn't want to stop using a super well-proven retinol for a newbie like Bakuchiol, we have good news. The two also work very nicely together and Bakuchiol can actually help to stabilize the otherwise unstable and hard to formulate retinol.
And we are still not done, as Bakuchiol shows not only anti-aging properties but also nice anti-acne effects. 1% Bakuchiol seems to be very effective in itself (57% reduction in acne after 6 weeks treatment) and even better when combined with 2% salicylic acid (67% reduction in acne after 6 weeks). We like that Bakuchiol is such a good team player! The molecule works against acne in multiple ways: It downregulates 5α-reductase (a sebum-controlling enzyme), it is antibacterial (including P. acnes), anti-inflammatory and it inhibits lipid-peroxidation, an evil oxidative process that is recently thought to be a very early trigger in the acne process.
We feel that this description is becoming very long so we will just mention that Bakuchiol also seems to positively regulate hydration-related genes such as Aquaporin 3 and also shows some melanin-inhibiting properties.
Overall, we think Bakuchiol is an awesome molecule with lots of promise both for anti-aging and anti-acne. But the proof compared to the well-established superstars is far from solid, so in a skincare routine, we would rather add Bakuchiol next to retinol than straight up replace it. Unless you are a gimme-the-newest-shiny-thing-under-the-sun-type.
The emollient plant oil coming from the soybean. It is considered to be a nice, cost-effective base oil with moisturizing properties. As for its fatty acid profile, it contains 48-59% barrier-repairing linoleic acid, 17-30% nourishing oleic acid and also some (4.5-11%) potentially anti-inflammatory linolenic acid.
Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA.
So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh.
There is also some research showing that citric acid with regular use (think three months and 20% concentration) can help sun-damaged skin, increase skin thickness and some nice hydrating things called glycosaminoglycans in the skin.
But according to a comparative study done in 1995, citric acid has less skin improving magic properties than glycolic or lactic acid. Probably that’s why citric acid is usually not used as an exfoliant but more as a helper ingredient in small amounts to adjust the pH of a formulation.
A little helper ingredient that is used to adjust the pH of the product. It also helps to keep products stay nice longer by neutralizing the metal ions in the formula (they usually come from water).
A non-essential amino acid (the building blocks of skin proteins, like collagen or elastin), that the body can produce itself, but its production decreases with age. When you put it all over your face, it works as a moisturizer and maybe more.
According to great skincare blog Futurederm, glycine might help with wound healing and tissue repair and when used together with other amino acids, leucine and proline it might improve wrinkles.
BTW, it's also a building block of a bunch of important and famous peptides, including copper-tripeptide-1, palmitoyl tripeptide-1 or palmitoyl hexapeptide-12.
- Retinol (pure Vitamin A) is probably the most proven anti-aging ingredient available OTC
- It has to be converted in the skin to retinoic acid to work its magic
- Once converted, it has the same effect as all-trans-retinoic acid, aka tretinoin
- A generally accepted ballpark number is that retinol is 10-to-20 times less potent than retinoic acid
- It makes skin less wrinkled, smoother, firmer and tighter
- It might also be helpful for acne prone skin as it normalizes keratinization and makes the pores produce less sebum
- Possible side effects and irritation are also much less than with retinoic acid
- Do not use whilst pregnant
It's the acronym for Butylated Hydroxy Toluene. It's a common synthetic antioxidant that's used as a preservative.
There is some controversy around BHT. It's not a new ingredient, it has been used both as a food and cosmetics additive since the 1970s. Plenty of studies tried to examine if it's a carcinogen or not. This Truth in Aging article details the situation and also writes that all these studies examine BHT when taken orally.
As for cosmetics, the CIR (Cosmetic Ingredient Review) concluded that the amount of BHT used in cosmetic products is low (usually around 0.01-0.1%), it does not penetrate skin far enough to be absorbed into the bloodstream and it is safe to use in cosmetics.
- GHK-Cu is a copper-peptide complex found naturally in yucky bodily fluids (plasma, saliva, and urine)
- It has unique wound healing properties by stimulating the breakdown of unhealthy, too large collagen in scar tissue and stimulating nice and healthy collagen production afterwards
- It stimulates the production of several important skin-identical ingredients (e.g. collagen, elastin, and glycosaminoglycans)
- It has significant anti-inflammatory and antioxidant effect
- There are a few promising studies showing GHK-Cu can improve skin elasticity, clarity, firmness and reduce lines and wrinkles
- It can improve hair growth by enlarging hair follicles (and bigger follicles produce longer, thicker hair)
- There are some urban legends about possible overdosing or facial hair problems (read more in geeky details)
A pretty famous and better-researched peptide consisting of five amino acids (the building blocks of all proteins). It was created in a joint effort by the French ingredient supplier, Sederma and the cosmetics industry big shot, Procter&Gamble.
The amino acid sequence of the peptide is lysine–threonine–threonine–lysine–serine (KTTKS). Sometimes, it's also called collagen pentapeptide, as it's a subfragment of skin-structure-giving type I collagen. The KTTKS amino sequence is then attached for better oil solubility and skin penetration to palmitic acid and BOOM; we get Palmitoyl Pentapeptide-4.
Though most research is manufacturer sponsored, the clinical studies about Palmitoyl Pentapeptide-4 are promising. In short, it can reduce fine lines, wrinkles and improve skin texture significantly (and at crazy low concentrations, the studies were done with just 3 ppm that is 0.0003%).
There are also studies comparing Palmitoyl Pentapeptide-4 with anti-aging gold standard, retinol. One of them compared 3ppm Pal-KTTKS with 700 ppm (0.07%) retinol and found that they showed similar wrinkle improving ability with the peptide showing better skin tolerability.
Bottom line, if you are into peptides, this is a good one to try.
Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!).
If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.
Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!).
A common fragrance ingredient that smells like jasmine. It is one of the “EU 26 fragrances” that has to be labelled separately because of allergen potential. Best to avoid if your skin is sensitive.
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| what‑it‑does | solvent |
| what‑it‑does | solvent |
| what‑it‑does | moisturizer/humectant | emollient | viscosity controlling |
| irritancy, com. | 0, 0 |
| what‑it‑does | solvent |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | emollient | perfuming |
| what‑it‑does | emollient | emulsifying |
| what‑it‑does | viscosity controlling |
| irritancy, com. | 0, 0 |
| what‑it‑does | soothing |
| irritancy, com. | 0, 0 |
| what‑it‑does | viscosity controlling |
| irritancy, com. | 0, 1 |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | preservative |
| what‑it‑does | moisturizer/humectant | emollient |
| what‑it‑does | surfactant/cleansing | emulsifying |
| what‑it‑does | chelating |
| what‑it‑does | moisturizer/humectant | solvent |
| irritancy, com. | 0, 1 |
| what‑it‑does | cell-communicating ingredient | antioxidant | antimicrobial/antibacterial |
| what‑it‑does | emollient | perfuming |
| irritancy, com. | 0, 3 |
| what‑it‑does | buffering |
| what‑it‑does | chelating | buffering |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | antioxidant | preservative |
| what‑it‑does | cell-communicating ingredient | soothing | antioxidant |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | perfuming |
| what‑it‑does | perfuming |