Derm-a-renew
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Vivant Skin Care Derm-a-renewIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
- It's a helper ingredient that improves the freeze-thaw stability of products
- It's also a solvent, humectant and to some extent a penetration enhancer
- It has a bad reputation among natural cosmetics advocates but cosmetic scientists and toxicology experts do not agree (read more in the geeky details section)
A mainly oil loving molecule that helps water and oil to mix nicely, aka emulsifier. In itself, it can create water-in-oil emulsions (when water droplets are dispersed in oil), but it is used mostly next to water-loving emulsifiers to create nice and smooth oil-in-water creams. It can also function as a wetting and dispersing agent helping insoluble particles such as color pigments or inorganic sunscreens (zinc/titanium dioxide) to disperse nice and even in liquids.
Chemically speaking, this molecule is "halfway" between Sorbitan Oleate and Sorbitan Trioleate, meaning that it is also an attachment of sorbitan (a dehydrated sorbitol (sugar) molecule) with the unsaturated fatty acid Oleic Acid, but in a ratio of 2:3 hence the "Sesqui" part in the molecule's name.
Ethylhexyl Dimethyl PABA is a chemical sunscreen agent that protects in the UVB range (290-320 nm) with a peak absorbance at 312nm. Other than that, we struggle to write anything positive about this guy, as it is photo unstable (looses 10% efficacy in 20 mins and 50% in 85 mins), not an unfrequent allergen in sunscreens and shows some endocrine effect in animal studies.
All this does not mean that it is not considered safe as used, it is (and is approved up to 8% in the EU and US and up to 3% in Japan), but we do think that there are plenty of other and better UV filters out there.
- A multi-functional skincare superstar with several proven benefits for the skin
- Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
- Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
- Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
- Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
Retinyl Propionate (RP) is a less well-known, but pretty interesting member of the retinoids, aka the "royal family of skincare". You can read the who's who here but the TL;DR version is that tretinoin is the king himself (the FDA-proven anti-aging active molecule), retinol is like Prince George (two conversion steps needed to be active) and Retinyl Palmitate is like Prince Charlotte (George's little sister), 3 steps away from the throne.
Similar to Retinyl Palmitate, Retinyl Propionate is also a retinol ester with retinol and propionic acid being attached together. This puts our molecule in the place of little Princess Charlotte on the family tree, quite far away from the throne. However, not all retinol ester molecules are made equal when it comes to being transformed and being effective on the skin.
As Dr. Fulton (the scientist behind both Retin-A and RP) puts it in his patent paper, "Other esters of vitamin A obtained from, for example, palmitic acid and acetic acid do not have the therapeutic advantages found with vitamin A propionate ..... Presumably, the [Retinyl Palmitate] molecule is so large, it is not able to transdermally reach the necessary part of the skin for activity. Similarly, vitamin A acetate is too small molecularly and therefore easily recrystallizes from any solution.....vitamin A propionate is the appropriate molecular weight and configuration to both remain in a stable solution and to be transdermally delivered to a site where it is active." So while the effectiveness of other retinol esters is highly questionable, Retinyl Propionate seems to be the most effective retinol ester molecule, and it "unexpectedly provides all the benefits of vitamin A acid but minimizes the negative side effects", at least according to Dr. Fulton, the inventor of the molecule.
We know what you are thinking! This sounds great and all, but what about some proof? Some backup data not from the inventor himself? We looked into it and found three studies working with Retinyl Propionate.
In a 2007 study by Dr. Draelos, she references a 12-week, double-blind, placebo-controlled clinical trial that compared the effectiveness of 0.15% retinol with 0.3% Retinyl Propionate. Both actives were effective in reducing the appearance of facial wrinkles and hyperpigmentation and the 0.3% RP worked a bit better.
Another research that was done by Procter & Gamble combined multiple anti-aging actives including niacinamide, peptides and 0.3% of Retinyl Propionate and they compared this regimen with a 0.02% tretinoin regimen. They found that the cosmetic regimen was tolerated better, worked faster and gave comparable results. All this sounds very promising for RP, however, it is hard to know how much the other actives contributed to the positive results.
Last, but not least there is a study from 1998 that tested a 0.15% Retinyl Propionate cream and after 24 weeks found no statistically significant difference between the effects of the retinyl propionate cream and the placebo preparation for any of the clinical parameters of skin photoaging. However, after 48 weeks, the 0.15% RP worked wonders for actinic keratoses, a rough, scaly patch caused by UV damage (its name contains actinic, but it is not acne, has nothing to do with it (!)).
So, it seems that the minimum effective dose of Retinyl Propionate is larger than 0.15% which is not surprising given that it has to do three conversion steps to reach the active form, retinoic acid. But 0.3% RP (or more, obvs) seems to be an effective dose, and even though the proof is not as solid as it is for retinol itself, if you are looking for a more gentle alternative, or if you are in the mood for experimentation, Retinyl Propionate looks like a noteworthy alternative and the most promising option among retinol esters.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
A waxy solid material that helps oil and water to mix together, aka emulsifier. It is derived from the fatty alcohol called stearyl alcohol by ethoxylating it and thus making the molecule more water-soluble.
The end result is a mostly water-loving emulsifier, also called solubilizer that can help to dissolve small amounts of oil-loving ingredients into water-based products. Or it can be combined with more oil-loving emulsifiers (such as its sister, Steareth-2) to create stable emulsions.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
A six amino acid peptide that is claimed to improve firmness and skin tone. Its amino acid sequence is Val-Gly-Val-Ala-Pro-Gly that is also called the "spring fragment" and is repeated six times in the important skin protein, elastin molecule.
The manufacturer made a double-blind, one-month long clinical study on 10 women and found that twice a day application of 4% Biopeptide El improved skin firmness by 33% and skin tone by 20%.
A four amino acid peptide with the amino sequence of glycine-glutamine-proline-arginine. It is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration.
It works by reducing the production of the signal molecule, interleukin-6 (IL-6) which promotes inflammation in the skin and less inflammation means slower degradation of important things (like collagen) that results in younger looking skin for a longer time.
It works in synergy with its pal, Palmitoyl Tripeptide-1 in the famous Matrixyl 3000 complex. You can read some more about the famous duo here.
A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula. It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.
It's the acronym for Butylated Hydroxy Toluene. It's a common synthetic antioxidant that's used as a preservative.
There is some controversy around BHT. It's not a new ingredient, it has been used both as a food and cosmetics additive since the 1970s. Plenty of studies tried to examine if it's a carcinogen or not. This Truth in Aging article details the situation and also writes that all these studies examine BHT when taken orally.
As for cosmetics, the CIR (Cosmetic Ingredient Review) concluded that the amount of BHT used in cosmetic products is low (usually around 0.01-0.1%), it does not penetrate skin far enough to be absorbed into the bloodstream and it is safe to use in cosmetics.
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
It is typically used in tiny amounts, around 0.1% or less.
The sodium salt of lactic acid. It's a great skin moisturizer and also used to regulate the pH value of the cosmetic formula. It's a natural ingredient approved by both ECOCERT and COSMOS.
PCA stands for Pyrrolidone Carboxylic Acid and though it might not sound like it, it is a thing that can be found naturally in our skin. The sodium salt form of PCA is an important skin-identical ingredient and great natural moisturizer that helps the skin to hold onto water and stay nicely hydrated.
A non-essential amino acid (the building blocks of skin proteins, like collagen or elastin), that the body can produce itself, but its production decreases with age. When you put it all over your face, it works as a moisturizer and maybe more.
According to great skincare blog Futurederm, glycine might help with wound healing and tissue repair and when used together with other amino acids, leucine and proline it might improve wrinkles.
BTW, it's also a building block of a bunch of important and famous peptides, including copper-tripeptide-1, palmitoyl tripeptide-1 or palmitoyl hexapeptide-12.
Fancy name for fruit sugar. It has nice water-binding properties and helps to keep skin hydrated.
Yes, it's the thing that can be found naturally in pee. And in the skin. It is an awesome natural moisturizing factor, aka NMF. NMFs are important components that help the skin to hold onto water and keep it plump, elastic and hydrated. Urea makes up about 7% of NMFs next to other things such as amino acids (40%), PCA (12%) or Lactate (12%).
What makes urea special, is that it is not only a simple moisturizer, but it is thought to be a "small-molecule regulator of epidermal structure and function" meaning that it has a bunch of extra biological activities. It acts as a mild keratolytic agent (some of its moisturizing action is thought to come from urea's ability to break down bonds in the protein called filaggrin and thus freeing up amino acids in the skin), enhances antimicrobial peptide expression and improves skin barrier function.
Being a mild keratolytic agent and strong moisturizer means that high-percentage (10-40%) urea treatments are found effective in a bunch of skin disorders connected to excessive dryness and malfunctioning skin barrier such as ichthyosis, xerosis, psoriasis, eczema and seborrheic dermatitis.
Overall, just like glycerin, urea is a real oldie but a goodie, a nice ingredient in any moisturizer.
- A multi-functional skincare superstar with several proven benefits for the skin
- Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
- Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
- Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
- Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi.
It’s pH dependent and works best at acidic pH levels (3-5). It’s not strong enough to be used in itself so it’s always combined with something else, often with potassium sorbate.
- It’s the second most researched AHA after glycolic acid
- It gently lifts off dead skin cells to reveal newer, fresher, smoother skin
- It also has amazing skin hydrating properties
- In higher concentration (10% and up) it improves skin firmness, thickness and wrinkles
- Choose a product where you know the concentration and pH value because these two greatly influence effectiveness
- Don’t forget to use your sunscreen (in any case but especially so next to an AHA product)
If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.
Also, it's an effective deodorant and a medium spreading emollient.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
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| what‑it‑does | solvent |
| what‑it‑does | moisturizer/humectant | solvent |
| irritancy, com. | 0, 0 |
| what‑it‑does | emulsifying |
| irritancy, com. | 0, 0-1 |
| what‑it‑does | sunscreen |
| what‑it‑does | cell-communicating ingredient | skin brightening | anti-acne | moisturizer/humectant |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | emulsifying | surfactant/cleansing |
| irritancy, com. | 1, 2 |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | viscosity controlling |
| irritancy, com. | 0, 1 |
| what‑it‑does | antioxidant | preservative |
| what‑it‑does | emollient |
| what‑it‑does | chelating |
| what‑it‑does | buffering | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| what‑it‑does | cell-communicating ingredient | skin brightening | anti-acne | moisturizer/humectant |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | preservative |
| what‑it‑does | exfoliant | moisturizer/humectant | buffering |
| what‑it‑does | preservative |
| what‑it‑does | preservative |