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NUO Derm Retinol Cream

Retinol Cream

Prevents, smoothes and treats wrinkles and fine lines, stimulating skin cell renewal improves skin texture and minimizes the appearance of enlarged pores combats and prevents the appearance of acne gives uniformity and brightness to the skin
Uploaded by: rockbgd on

Highlights

#alcohol-free #fragrance & essentialoil-free
Alcohol Free
Fragrance and Essential Oil Free

Skim through

Ingredient name what-it-does irr., com. ID-Rating
Rosa Damascena Flower Water
Caprylic/Capric Triglyceride emollient
Butylene Glycol moisturizer/​humectant, solvent 0, 1
Propanediol solvent, moisturizer/​humectant
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Bakuchiol cell-communicating ingredient, antioxidant, antimicrobial/​antibacterial goodie
Niacinamide cell-communicating ingredient, skin brightening, anti-acne, moisturizer/​humectant superstar
1,2-Hexanediol solvent
Cetearyl Alcohol emollient, viscosity controlling, emulsifying, surfactant/​cleansing 1, 2
Rosa Canina Seed Oil emollient goodie
Polyacrylate-13
Leontopodium Alpinum Callus Culture Extract antioxidant, soothing, moisturizer/​humectant goodie
Sodium Hyaluronate skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Copper Tripeptide-1 cell-communicating ingredient, soothing, antioxidant goodie
Galloyl Pentapeptide-33 antioxidant
Centella Asiatica Extract soothing, antioxidant, moisturizer/​humectant goodie
Houttuynia Cordata Extract antioxidant, soothing goodie
Betula Platyphylla Japonica Juice
Dioscorea Japonica Root Extract
Anthemis Nobilis Flower Extract soothing, perfuming goodie
Calendula Officinalis Flower Extract soothing, antioxidant, perfuming goodie
Retinol cell-communicating ingredient superstar
Ceramide NP skin-identical ingredient goodie
Cetearyl Olivate emulsifying goodie
Sorbitan Olivate emulsifying goodie
Sucrose Palmitate emollient, emulsifying, surfactant/​cleansing
Hydrogenated Lecithin emollient, emulsifying goodie
Tocopheryl Acetate antioxidant 0, 0
Alpha-Bisabolol soothing goodie
Asiaticoside antioxidant, perfuming goodie
Asiatic Acid goodie
Madecassic Acid goodie
Madecassoside antioxidant, soothing goodie

NUO Derm Retinol Cream
Ingredients explained

Also-called: Damask Rose Flower Water, Rose Hydrosol

The flower water coming from the flowers of the Damask Rose. In general, flower waters (also called hydrosols) are diluted versions of essential oils coming from the same plant. They contain the same components but in much-reduced concentrations.

Similar to its big sister, rose oil, rose water also has a lovely, relaxing scent. It contains some antioxidant and antimicrobial compounds, as well as some fragrant components

What-it-does: emollient

A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular. 

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

Also-called: Zemea | What-it-does: solvent, moisturizer/humectant

Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved. 

It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. 

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

Bakuchiol - goodie
Also-called: Sytenol A, Phyto Retinol | What-it-does: cell-communicating ingredient, antioxidant, antimicrobial/antibacterial

At first glance, you could think that Bakuchiol is your average plant extract. It is derived from the seeds of Psoralea Corylifolia, aka Babchi, a plant important in Indian and Chinese medicine. The molecule was first isolated in 1973 and several anti-something properties are known about it: it has anti-inflammatory, antioxidant, anti-tumor, anti-bacterial and hepatoprotective magical abilities like plenty of other Ayurvedic plant extracts.

What makes Bakuchiol a special snowflake is the recent discovery that it behaves on the skin in a way very similar to well-known skincare superstar, retinol. While chemically, it has nothing to do with the vitamin-A family, aka retinoids, comparative gene expression profiling (a fancy way of saying that they compared how retinol and bakuchiol modify the way  skin cells behave and produce important skin proteins such as collagen) shows that retinol and bakuchiol regulate skin cell behavior in a similar way. 

Niacinamide - superstar
Also-called: vitamin B3, nicotinamide | What-it-does: cell-communicating ingredient, skin brightening, anti-acne, moisturizer/humectant
  • A multi-functional skincare superstar with several proven benefits for the skin
  • Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
  • Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
  • Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
  • Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
Read all the geeky details about Niacinamide here >>

What-it-does: solvent

A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives

What-it-does: emollient, viscosity controlling, emulsifying, emulsion stabilising, surfactant/cleansing | Irritancy: 1 | Comedogenicity: 2

An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.  

It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols.  Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.

Also-called: Dog-Rose Seed Oil, Rosehip Seed Oil | What-it-does: emollient

The oil coming from the seeds of dog-rose, a wild rose species native to Europe, northwest Africa and western Asia. It's a nice emollient, moisturizing plant oil loaded with skin-nourishing fatty acids (linoleic acid - 51%, linolenic acid - 19% and oleic acid - 20%). 

If you start to dig a bit deeper into the rosehip oil topic, you will soon see that there are lots of species of rose, and it's all a bit confusing to know what the differences and similarities between the oils of the different roses are. As far as our research can tell, here is the gist.

A helper ingredient that functions as a film-forming polymer (big molecule from repeated subunits).

It usually comes to the formula as part of a thickener-emulsifier trio paired with Polyisobutene and Polysorbate 20. The three togeather have excellent thickening properties with remarkable emulsifying-stabilising abilities. They also have a nice silicone feel with glide-on spreading. 

Also-called: Majestem, Edelweiss Stem Cell Extract | What-it-does: antioxidant, soothing, moisturizer/humectant

A plant stem cell extract derived from the famous mountain flower, Edelweiss. It goes by the trade name Majestem and the manufacturer claims that it has a visible lifting action on the neck and face.

In their in-vivo (made on real people) tests, the sagging skin on the neck was tightened by -10.6% up to -56% in three weeks. After six weeks, the cheeks were also lifted and the crow’s feet wrinkles were smoothed out (surface -11% up to -75%).

What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It’s the - sodium form - cousin of the famous NMFhyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

Also-called: GHK-Cu, Copper Peptide | What-it-does: cell-communicating ingredient, soothing, antioxidant
  • GHK-Cu is a copper-peptide complex found naturally in yucky bodily fluids (plasma, saliva, and urine)
  • It has unique wound healing properties by stimulating the breakdown of unhealthy, too large collagen in scar tissue and stimulating nice and healthy collagen production afterwards
  • It stimulates the production of several important skin-identical ingredients (e.g. collagen, elastin, and glycosaminoglycans)
  • It has significant anti-inflammatory and antioxidant effect
  • There are a few promising studies showing GHK-Cu can improve skin elasticity, clarity, firmness and reduce lines and wrinkles
  • It can improve hair growth by enlarging hair follicles (and bigger follicles produce longer, thicker hair)
  • There are some urban legends about possible overdosing or facial hair problems (read more in geeky details)
Read all the geeky details about Copper Tripeptide-1 here >>

What-it-does: antioxidant

We don't have description for this ingredient yet.

Also-called: Gotu Kola, Tiger Grass | What-it-does: soothing, antioxidant, moisturizer/humectant

Centella Asiatica - or sometimes also called Gotu Kola or Cica - has been used in folk medicine for hundreds of years. It’s traditionally used to improve small wounds, burns and scratches and it’s also a well known anti-inflammatory agent for eczema.

Recently science has taken an interest in Gotu Kola as well and it turns out it really has many active compounds with several benefits. Just for hard-core geeks, the main biologically active compounds are pentacyclic triterpenoid saponins called asiaticoside, madecassoside, asiatic and madecassic acid (also called centellosides).

What-it-does: antioxidant, soothing

Houttuynia cordata is a flowering plant native to Southeast Asia. It is eaten as a leaf vegetable, and also has a long history of use in traditional Chinese medicine, including as an attempted treatment for SARS (it didn’t really work). Regarding cosmetics, however, houttuynia cordata extract has a good bit of potential! 

The main active components in the plant are these fancy chemicals called flavonoids. Houttuynia cordata specifically has a good amount of polyphenolic flavonoids, four common ones being quercetin, quercitrin, hyperoside, and rutin. All of these exhibit anti-inflammatory, antioxidant, and antibacterial properties. Quercitrin has also been shown to decrease damage from UVB rays, which is an added bonus. One thing to keep in mind, though, is that the flavonoid content of this extract can depend on if the extract is taken from the roots or the leaves, as well as if it’s a water extraction or an alcohol extraction.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Also-called: Roman Chamomile Flower Extract | What-it-does: soothing, perfuming

There are two primary types of Chamomile, the German and the Roman. Both has soothing properties, but the German one contains more anti-inflammatory actives (like chamazulene). The anti-inflammatory action of the Roman Chamomile is due to phenolic compounds and -  according to manufacturer info- it also has some nice skin toning properties.

Also-called: Calendula Extract, Marigold Extract | What-it-does: soothing, antioxidant, perfuming

The extract coming from the popular garden plant Calendula or Marigold. According to manufacturer info, it's used  for many centuries for its exceptional healing powers and is particularly remarkable in the treatment of wounds. It contains flavonoids that give the plant anti-inflammatory and antioxidant properties. 

Retinol - superstar
Also-called: Vitamin A, Form of Retinoids | What-it-does: cell-communicating ingredient
  • Retinol (pure Vitamin A) is probably the most proven anti-aging ingredient available OTC
  • It has to be converted in the skin to retinoic acid to work its magic
  • Once converted, it has the same effect as all-trans-retinoic acid, aka tretinoin
  • A generally accepted ballpark number is that retinol is 10-to-20 times less potent than retinoic acid
  • It makes skin less wrinkled, smoother, firmer and tighter
  • It might also be helpful for acne prone skin as it normalizes keratinization and makes the pores produce less sebum
  • Possible side effects and irritation are also much less than with retinoic acid
  • Do not use whilst pregnant
Read all the geeky details about Retinol here >>

Ceramide NP - goodie
Also-called: Ceramide 3 | What-it-does: skin-identical ingredient

One of the many types of ceramides that can be found naturally in the upper layer of the skin. Ceramides make up about 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated. It works even better when combined with its pal, Ceramide 1.

We wrote way more about ceramides at ceramide 1, so click here to know more.

Also-called: Part of Olivem 1000 | What-it-does: emulsifying

An ester that comes from Cetearyl alcohol and the fatty acids of olive oil. It often comes to the formula coupled with Sorbitan Olivate as the two together form the well-known, natural emulsifier trade named Olivem 1000. 

Other than helping oil and water to blend, the main thing of Olivem 1000 is generating liquid crystal structures that are similar to the lipid structures of the stratum corneum (the outermost layer of the skin). Thanks to this, Olivem 1000 doubles as an active ingredient with significant moisturizing, barrier-repairing and soothing properties.

Also-called: Part of Olivem 1000 | What-it-does: emulsifying

An ester coming from sorbitol and the fatty acids of olive oil. It is part of the popular emulsifier trade named Olivem 1000 that is well-known for generating biomimetic liquid crystal structures. We have more info on Olivem 1000 at Cetearyl Olivate >>

A sugar ester (sucrose + palmitic acid) that works as a natural emulsifier (helps oil and water to mix). According to the manufacturer, it has a great skin-feel, improves smoothness, emolliency and even hydrates the skin.

Combined with another sugar ester, sucrose stearate, it can improve high temperature stability of Sucragel based oily gel cleansers.

What-it-does: emollient, emulsifying

It's the chemically chopped up version of normal lecithin. Most often it's used to create liposomes and to coat and stabilize other ingredients. 

Also-called: Vitamin E Acetate | What-it-does: antioxidant | Irritancy: 0 | Comedogenicity: 0

It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version. 

According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E. 

Also-called: Bisabolol | What-it-does: soothing

It's one of the active parts of Chamomile that contains about 30% of bisabolol. It's a clear oily fluid that is used in skincare as a nice anti-inflammatory and soothing ingredient. 

Asiaticoside - goodie
What-it-does: antioxidant, perfuming

One of the main biologically active components of the famous medicinal plant, Centella Asiatica, aka Gotu Kola. It has well established wound healing and antioxidant activities.  

In-vitro (made in the lab) studies also show that Asiaticoside stimulates GAGs (glycosaminoglycans - polysaccharides that are part of the liquidy stuff between our skin cells) production as well as collagen I synthesis.  Read more at Gotu Kola >>

Asiatic Acid - goodie

One of the biologically active components of Gotu Kola. It's a bit less prominent than its sister component, Asiaticoside, but in-vitro (made in the lab) studies show that Asiatic Acid also stimulates GAGs (glycosaminoglycans - polysaccharides that are part of the liquidy stuff between our skin cells) production as well as collagen I synthesis.

English translation equals that it probably contributes to the well-established moisturizing and wound healing abilities of Gotu Kola

One of the biologically active components of Gotu Kola that is thought to contribute to the plant extract's well-documented skin regenerating, wound healing, and moisturizing properties

If you are into Gotu Kola we have some more info at Centella Asiatica Extract and its other biologically active components MadecassosideAsiaticoside and Asiatic Acid.

Madecassoside - goodie
What-it-does: antioxidant, soothing

One of the main biologically active components of the famous medicinal plant, Centella Asiatica, aka Gotu Kola. It has well established wound healing, skin-soothing and antioxidant activities.

There is also a study by La Roche Posay (belongs to L'Oreal) that examined the anti-aging effects of 5% Vitamin C combined with 0.1% Madecassoside. They mention that " Madecassoside is known to induce collagen expression and ⁄ or to modulate inflammatory mediators thus might  prevent and correct some signs of aging." The surprisingly long, 6-month study observed "significant improvement of the clinical score for deep and superficial wrinkles, suppleness, firmness, roughness, and skin hydration", but Vitamin C in itself is already an anti-aging superstar, so it is hard to know how much Madecassoside did. 

You may also want to take a look at...

Rose flower water that has a lovely relaxing scent. Contains some antioxidant and antimicrobial compounds, as well as some fragrant components.  [more]
what‑it‑does emollient
A very common emollient that makes your skin feel nice and smooth. Comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. [more]
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0, 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
what‑it‑does solvent | moisturizer/humectant
A natural corn sugar derived glycol. It can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
what‑it‑does cell-communicating ingredient | antioxidant | antimicrobial/antibacterial
At first glance, you could think that Bakuchiol is your average plant extract. It is derived from the seeds of Psoralea Corylifolia, aka Babchi, a plant important in Indian and Chinese medicine. [more]
what‑it‑does cell-communicating ingredient | skin brightening | anti-acne | moisturizer/humectant
A multi-functional skincare superstar that has clinically proven anti-aging, skin lightening, anti-inflammatory and barrier repair properties. [more]
what‑it‑does solvent
A multi-functional helper ingredient that acts as a humectant and emollient. It's also a solvent and can boost the effectiveness of preservatives. [more]
what‑it‑does emollient | viscosity controlling | emulsifying | surfactant/cleansing
irritancy, com. 1, 2
A super common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams. [more]
what‑it‑does emollient
The oil coming from dog-rose. A nice emollient, moisturizing plant oil loaded with skin-nourishing fatty acids (linoleic acid - 51%, linolenic acid - 19% and oleic acid - 20%). [more]
A film forming polymer that usually comes to the formula as part of a thickener-emulsifier trio paired with Polyisobutene and Polysorbate 20. [more]
what‑it‑does antioxidant | soothing | moisturizer/humectant
Edelweiss Stem Cell Extract that's claimed to have a visible lifting action on the neck and face. It also contains leontopodic acid that's a potent anti-inflammatory agent. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
what‑it‑does cell-communicating ingredient | soothing | antioxidant
A copper-peptide complex that has unique wound healing and skin remodelling properties. It's also an anti-inflammatory and antioxidant agent. [more]
what‑it‑does antioxidant
what‑it‑does soothing | antioxidant | moisturizer/humectant
Centella Asiatica - or sometimes also called Gotu Kola or Cica - has been used in folk medicine for hundreds of years. It’s traditionally used to improve small wounds, burns and scratches and it’s also a well known anti-inflammatory agent for eczema. Recently science has taken an interest in Gotu Kola as well and it turns out it really has many active compounds with several benefits. [more]
what‑it‑does antioxidant | soothing
A flavonoid-rich plant extract known mainly for its soothing and antioxidant properties. [more]
what‑it‑does soothing | perfuming
Roman Chamomile - thanks to its phenolic compound had some nice soothing and skin toning properties. It contains less anti-inflammatory actives than the German Chamomile. [more]
what‑it‑does soothing | antioxidant | perfuming
Marigold extract - contains flavonoids that give the plant anti-inflammatory and antioxidant properties. [more]
what‑it‑does cell-communicating ingredient
Vitamin A - the most proven anti-aging ingredient available OTC that can smooth wrinkles and make skin firmer. It might also be useful for acne-prone skin as it normalizes keratinization. [more]
what‑it‑does skin-identical ingredient
Ceramides make up 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated.  [more]
what‑it‑does emulsifying
Part of Olivem 1000, a natural emulsifier duo that is known for forming biomimetic liquid crystal structures. It doubles as an active ingredient with barrier repairing and soothing properties. [more]
what‑it‑does emulsifying
An ester coming from sorbitol and the fatty acids of olive oil. It often comes to the formula coupled with Cetearyl Olivate and the two together help water and oil to blend (emulsifier). It's a natural and Ecocert approved duo.
what‑it‑does emollient | emulsifying | surfactant/cleansing
A sugar ester (sucrose + palmitic acid) that works as a natural emulsifier. It also has a great skin-feel, improves smoothness, emolliency and even hydrates the skin. [more]
what‑it‑does emollient | emulsifying
It's the chemically chopped up version of normal lecithin. Most often it's used to create liposomes and to coat and stabilize some other ingredient. 
what‑it‑does antioxidant
irritancy, com. 0, 0
A form of vitamin E that works as an antioxidant. Compared to the pure form it's more stable, has longer shelf life, but it's also more poorly absorbed by the skin. [more]
what‑it‑does soothing
One of the active parts of Chamomile that is used in skincare as a nice anti-inflammatory and soothing ingredient. [more]
what‑it‑does antioxidant | perfuming
One of the main biologically active components of the famous medicinal plant, Centella Asiatica, aka Gotu Kola. It has well established wound healing and antioxidant activities.  In-vitro (made in the lab) studies also show that Asiaticoside stimulates GAGs (glycosaminoglycans - polysaccharides that are part of the liquidy stuff between our skin cells) production as well as coll [more]
One of the biologically active components of Gotu Kola. It's a bit less prominent than its sister component, Asiaticoside, but in-vitro (made in the lab) studies show that Asiatic Acid also stimulates GAGs (glycosaminoglycans - polysaccharides that are part of the liquidy stuff between our skin cells) production as well as collagen I synthesis. [more]
One of the biologically active components of Gotu Kola that is thought to contribute to the plant extract's well-documented skin regenerating, wound healing, and moisturizing properties. If you are into Gotu Kola we have some more info at Centella Asiatica Extract and its other biologically active components  [more]
what‑it‑does antioxidant | soothing
One of the main biologically active components of the famous medicinal plant, Centella Asiatica, aka Gotu Kola. It has well established wound healing, skin-soothing and antioxidant activities. There is also a study by La Roche Posay (belongs to L'Oreal) that examined the anti-aging effects of 5% Vitamin C combined with 0. [more]