Follow us on our new Insta page »
Neogen Dermalogy White Truffle Ampoule Drop Mist

Dermalogy White Truffle Ampoule Drop Mist

This micro-fine mist has the balancing texture with oil serum and water base essence. So it can be quickly and easily absorbed into your tired and dry skin without greasy and sticky finish on your skin. Containing White Truffle extracts, rich in Vitamins, Amino acid and Minerals, reinforce your skin barrier, brighten skin tone and hydrate from inside skin.
Uploaded by: anini on

Highlights

#alcohol-free
Alcohol Free

Skim through

Ingredient name what-it-does irr., com. ID-Rating
Water solvent
Dipropylene Glycol solvent, perfuming, viscosity controlling
Butylene Glycol moisturizer/​humectant, solvent, viscosity controlling 0, 1
Isononyl Isononanoate emollient
1,2-Hexanediol solvent
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Niacinamide cell-communicating ingredient, skin brightening, anti-acne, moisturizer/​humectant superstar
Betaine moisturizer/​humectant goodie
Ethylhexylglycerin preservative
Olea Europaea (Olive) Fruit Oil antioxidant, emollient, perfuming 0, 0-2 goodie
Adenosine cell-communicating ingredient goodie
Hippophae Rhamnoides Oil antioxidant, emollient goodie
Pelargonium Graveolens Flower Oil perfuming icky
Xanthan Gum viscosity controlling, emulsifying, surfactant/​cleansing
Panthenol soothing, moisturizer/​humectant 0, 0 goodie
Citrus Aurantium Dulcis (Orange) Peel Oil perfuming icky
Mentha Piperita (Peppermint) Oil perfuming icky
Lavandula Hybrida Oil emollient
Citrus Aurantium Bergamia (Bergamot) Fruit Oil perfuming icky
Rose Flower Oil
Chamomilla Recutita (Matricaria) Flower Oil soothing goodie
Hyaluronic Acid skin-identical ingredient, moisturizer/​humectant goodie
Sodium PCA skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Sodium Lactate buffering, moisturizer/​humectant goodie
Macadamia Integrifolia Seed Oil emollient goodie
Arginine skin-identical ingredient goodie
Aspartic Acid skin-identical ingredient goodie
Elaeis Guineensis (Palm) Oil emollient
Pca skin-identical ingredient, moisturizer/​humectant goodie
Ceramide NP skin-identical ingredient goodie
Cholesterol skin-identical ingredient, emollient 0, 0 goodie
Tuber Magnatum Extract(20Ppb)
Adansonia Digitata Seed Oil emollient goodie
Stearic Acid emollient, viscosity controlling 0, 2-3
Persea Gratissima (Avocado) Oil antioxidant, emollient 0, 0-3 goodie
Phytosphingosine skin-identical ingredient, cell-communicating ingredient, anti-acne, antimicrobial/​antibacterial goodie
Hydrolyzed Hyaluronic Acid moisturizer/​humectant goodie
Glycine skin-identical ingredient goodie
Alanine skin-identical ingredient goodie
Sodium Hyaluronate skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Serine skin-identical ingredient goodie
Valine skin-identical ingredient goodie
Isoleucine skin-identical ingredient goodie
Threonine skin-identical ingredient goodie
Proline skin-identical ingredient goodie
Phenylalanine skin-identical ingredient goodie
Histidine skin-identical ingredient, moisturizer/​humectant goodie
Disodium EDTA chelating, viscosity controlling

Neogen Dermalogy White Truffle Ampoule Drop Mist
Ingredients explained

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

A clear, colorless liquid that works as a solvent and viscosity decreasing ingredient. It also has great skin-moisturizing abilities. 

What-it-does: moisturizer/humectant, solvent, viscosity controlling | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive. 

What-it-does: emollient

An emollient ester with a rich and creamy but non-greasy skin feel. It makes skin supple and protects dry skin. 

What-it-does: solvent

A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot)
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

Niacinamide - superstar
Also-called: vitamin B3, nicotinamide | What-it-does: cell-communicating ingredient, skin brightening, anti-acne, moisturizer/humectant
  • A multi-functional skincare superstar with several proven benefits for the skin
  • Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
  • Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
  • Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
  • Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
Read all the geeky details about Niacinamide here >>

Betaine - goodie
What-it-does: moisturizer/humectant

A sugar beet derived amino acid derivative with nice skin protection and moisturization properties. Betain's special thing is being an osmolyte, a molecule that helps to control cell-water balance.  It is also a natural osmoprotectant, meaning that it attracts water away from the protein surface and thus protects them from denaturation and increases their thermodynamic stability. 

It also gives sensorial benefits to the formula and when used in cleansers, it helps to make them milder and gentler. 

What-it-does: preservative, deodorant

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient

Also-called: Olive Fruit Oil | What-it-does: antioxidant, emollient, perfuming | Irritancy: 0 | Comedogenicity: 0-2

You probably know olive oil from the kitchen as a great and healthy option for salad dressing but it's also a great and healthy option to moisturize and nourish the skin, especially if it's on the dry side. 

Similar to other emollient plant oils, it's loaded with nourishing fatty acids: oleic is the main component (55-83%), and also contains linoleic (3.5-20%) and palmitic acids (7-20%). It also contains antioxidant polyphenols, tocopherols (types of vitamin E) and carotenoids and it's one of the best plant sources of skin-identical emollient, Squalene

Overall, a great option for dry skin but less so for acne-prone or damaged skin.

Adenosine - goodie

Adenosine is an important little compound in our body that has a vital cell-signalling role. Research on smearing it on our face is also promising and shows so far a couple of things:

  • It can help with wound healing
  • It’s a good anti-inflammatory agent
  • It might even help with skin’s own collagen production and improve skin firmness and elasticity
  • It helps with barrier repair and protection
  • It might be even useful for the hair helping with hair thickness and hair growth
Also-called: Sea Buckthorn Berry Oil;Hippophae Rhamnoides Fruit Oil | What-it-does: antioxidant, emollient

The oil coming from the pulp of the sea buckthorn berry. It has a pretty unique fatty acid composition: 65% is a combination of the rare Omega-7, aka palmitoleic acid and the more common palmitic acid. Fatty acids give the oil nice moisturizing and skin-protecting abilities. 

But that's not all the goodness of sea buckthorn oil. It contains antioxidant superstar, Vitamin E (in multiple forms), antioxidant (and orange color giving) pigments beta-carotene and lycopene, as well as skin-soothing and replenishing beta-sitosterol

Btw, used undiluted, it will make your skin orange. 

All in all, a goodie emollient plant oil. 

Also-called: Rose Geranium Flower Essential Oil | What-it-does: perfuming

The fragrant essential oil coming from the flowers of Rose Geranium. Like most essential oils, it contains antioxidant and antimicrobial components, but the main ones are fragrant constituents (like citronellol and geraniol). Be careful with it, if your skin is sensitive. 

It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range. 

Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415). 

Panthenol - goodie
Also-called: Pro-Vitamin B5 | What-it-does: soothing, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid). 

Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier. 

Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.

Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation. 

If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.

As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily. 

Also-called: Sweet Orange Peel Oil, Citrus Sinensis Oil | What-it-does: perfuming

The essential oil coming from the rind of the orange (the sweet one). In general, the main component of citrus peel oils is limonene (83-97% for sweet orange peel), a super common fragrant ingredient that makes everything smell nice (but counts as a frequent skin sensitizer).

Other than that, citrus peel also contains the problematic compound called furanocoumarin that makes them mildly phototoxic. Orange peel contains less of it than some other citruses (like bergamot or lime), but still, be careful with it especially if it is in a product for daytime use.  

Also-called: Peppermint Oil | What-it-does: perfuming

The essential oil coming from steam distillation of freshly harvested, flowering peppermint sprigs. Its major component is menthol that gives the oil its well-known refreshing and cooling properties. Peppermint oil is traditionally used as an inhalant for cold and coughs and there is also some clinical data validating its use against headaches by rubbing a peppermint oil cream on the forehead. 

As for skincare, other than the nice grassy-minty smell and the refreshing sensations, we cannot write good things. It can be a skin irritant, so much so that it is a well-known counterirritant for muscle pains creating mild surface irritation to make things better in the deeper layers. But for everyday skincare, counterirritation is not something you wanna do, so we think that peppermint oil is better to avoid, especially if your skin is sensitive. 

What-it-does: emollient

We don't have description for this ingredient yet.

Also-called: Bergamot Fruit Oil | What-it-does: perfuming

The essential oil coming from the fruit (probably the rind) of the bergamot orange.  It's a common top note in perfumes and contains (among others) fragrant compounds limonene (37%), linalyl acetate (30%) and linalool (8.8%). 

A well-known issue with bergamot oil (apart from the fragrance allergens) is that it contains phototoxic compounds called furanocoumarins, but more and more commonly furanocoumarin-free versions are used in cosmetic products. Still, if you have sensitive skin and prefer fragrance-free products, bergamot oil is not for you.

We don't have description for this ingredient yet.

Also-called: German Chamomile Flower Oil | What-it-does: soothing

The essential oil coming from the German Chamomile. It's loaded with the famous anti-inflammatory agent, bisabolol (approx. 50%) and contains 5% of soothing, antiallergic and blue color giving chamazulene. It also contains about 120 other things, including 28 terpenoids and 36 flavonoids (including some antioxidants like quercetin).

As for skincare, the essential oil is used mainly for it's anti-inflammatory and soothing properties

  • It’s naturally in our skin and behaves there like a sponge
  • It can bind up to 1000 times its own weight in water
  • It is a big molecule from repeated subunits (polymer) so different molecular weight versions exist (unfortunately there is no way to determine MW from INCI list only)
  • High-molecular-weight-HA (>500 kDa) is an excellent surface hydrator, skin protectant and can act as an osmotic pump helping water-soluble actives to penetrate deeper into the skin
  • Low-molecular-weight-HA (< 500 kDa) can hydrate the skin somewhat deeper though it is still a big molecule and works mainly in the epidermis (outer layer of the skin)
  • Low-molecular-weight-HA might also help the skin to repair itself by increasing its self-defense (~ 200kDa used in the study)
  • Ultra-low-molecular-weight-HA (<50kDa) is a controversial ingredient and might work as a pro-inflammatory signal molecule
Read all the geeky details about Hyaluronic Acid here >>

Sodium PCA - goodie
Also-called: Sodium Pyrrolidone Carboxylic Acid | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

PCA stands for Pyrrolidone Carboxylic Acid and though it might not sound like it, it is a thing that can be found naturally in our skin. The sodium salt form of PCA is an important skin-identical ingredient and great natural moisturizer that helps the skin to hold onto water and stay nicely hydrated. 

The sodium salt of lactic acid. It's a great skin moisturizer and also used to regulate the pH value of the cosmetic formula. It's a natural ingredient approved by both ECOCERT and COSMOS.

Also-called: Macadamia Oil | What-it-does: emollient

The golden yellow oil coming from the Macadamia nut, a native Australian nut. Similar to other plant oils, it's loaded with emollient and nourishing fatty acids. It's a high oleic acid oil (50-67% oleic acid and only 0-5% linoleic acid) that makes it very emollient and ideal for dry skin types.

Its unique property is that it contains high amounts of a rare fatty acid called palmitoleic acid (12-25%) that give Macadamia oil a "cushiony" feel. It's also easily absorbed and makes the skin soft and supple. 

Arginine - goodie

A semi-essential (infants cannot synthesize it, but adults can) amino acid that is one of the primary building blocks of hair keratin and skin collagen. It's a natural moisturizing factor, a skin hydrator and might also help to speed up wound healing

Arginine usually has a positive charge (cationic) that makes it substantive to skin and hair (those are more negatively charged surfaces) and an excellent film former.  Thanks to the positive charge, it also creates a complex with AHAs (AHAs like to lose a hydrogen ion and be negatively charged, so the positive and the negative ions attract each other) that causes a "time-release AHA effect" and reduces the irritation associated with AHAs

Aspartic Acid - goodie

A non-essential amino acid  (important building block of collagen and elastin) that hydrates the skin. It is also used to set the pH of the cosmetic product (buffering).

What-it-does: emollient

We don't have description for this ingredient yet.

Pca - goodie
Also-called: Pyrrolidone Carboxylic Acid | What-it-does: skin-identical ingredient, moisturizer/humectant

PCA stands for Pyrrolidone Carboxylic Acid and though it might not sound like it, it is a thing that can be found naturally in our skin. In fact, after amino acids, it is the second biggest NMF component of the skin with 12% being PCA of the NMF composition of normal skin.  So similar to other NMFs, it's a skin goodie that helps the skin to hold onto water and stay nicely hydrated. 

Ceramide NP - goodie
Also-called: Ceramide 3 | What-it-does: skin-identical ingredient

One of the many types of ceramides that can be found naturally in the upper layer of the skin. Ceramides make up about 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated. It works even better when combined with its pal, Ceramide 1.

We wrote way more about ceramides at ceramide 1, so click here to know more.

Cholesterol - goodie
What-it-does: skin-identical ingredient, emollient | Irritancy: 0 | Comedogenicity: 0

It's one of the important lipids that can be found naturally in the outer layer of the skin. About 25% of the goopy stuff between our skin cells consists of cholesterol. Together with ceramides and fatty acids, they play a vital role in having a healthy skin barrier and keeping the skin hydrated. 

Apart from being an important skin-identical ingredient, it's also an emollient and stabilizer

We don't have description for this ingredient yet.

Also-called: Baobab Seed Oil | What-it-does: emollient

Baobab is a really big, iconic tree native to Africa (here is a nice image of it). It's the largest succulent plant in the world and almost all parts of it have traditional medicinal uses in Africa. 

The seed oil, similar to other plant oils, is loaded with things that are good-for-the-skin: it contains skin regenerating vitamin A, antioxidant vitamin E, and vitamin D3 that helps with calcium absorption. It's rich in nourishing fatty acids oleic (30-40%), linoleic (24-34%) and palmitic (18-30%).

Its moisturizing benefits are impressive, it absorbed into the skin quickly and might even improve skin elasticity. A great oil for drier skin types and excellent for eczema and psoriasis

What-it-does: emollient, viscosity controlling | Irritancy: 0 | Comedogenicity: 2-3

A common multi-tasker fatty acid. It makes your skin feel nice and smooth (emollient), gives body to cream type products and helps to stabilize water and oil mixes (aka emulsions).

Also-called: Avocado Oil, Persea Americana Oil | What-it-does: antioxidant, emollient | Irritancy: 0 | Comedogenicity: 0-3

The oil coming from the pulp of one of the most nutritious fruits in the world, the avocado. It's loaded with the nourishing and moisturizing fatty acid, oleic (70%) and contains some others including palmitic (10%) and linoleic acid (8%). It also contains a bunch of minerals and vitamins A, E and D

Avocado oil has extraordinary skin penetration abilities and can nourish different skin layers. It's a very rich, highly moisturizing emollient oil that makes the skin smooth and nourished. Thanks to its vitamin E content it also has some antioxidant properties. As a high-oleic plant oil, it is recommended for dry skin

It's a type of lipid, a so-called sphingoid base that can be found naturally in the upper layer of the skin. It's found both in "free-form" and as part of famous skin lipids, ceramides.

There is emerging research about Phytosphingosine that shows that it has antimicrobial and cell-communicating properties and is considered part of the skin's natural defense system.

A 2007 study showed that Phytosphingosine even works against evil acne-causing bacteria, Propionibacterium acnes and shows promise as a complementing active ingredient in treating acne-prone skin thanks to its anti-inflammatory and antimicrobial activities.  

A nice one to spot in the ingredient list. :)

What-it-does: moisturizer/humectant

Hydrolyzed Hyaluronic Acid is a low molecular weight, chemically chopped up version of the naturally big molecule and current IT-moisturizer, Hyaluronic Acid (HA). The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to retain water, making it plump and elastic. As HA is a polymer, the subunits can be repeated many times (as a high-molecular-weight version), or just a few times (as a low-molecular-weight version).

We wrote in detail at HA about how different molecular weight versions do different things both as a component of the skin and as a skincare ingredient, so click here and read about all the details. Hydrolyzed Hyaluronic Acid can also come in different molecular-weight versions with different properties:

  • 100-300 kDa version: apart from moisturizing, this size might also help the skin to repair itself by increasing its self-defense. It is also claimed to boost the wound healing process and is especially helpful for sensitive skin types (acne, rosacea, inflammation-related skin diseases). 
  • 50k Da version: this is the size that is claimed to be able to absorb into the skin and plump up wrinkles, so it is used mainly as an "anti-aging ingredient" 
  • below 50k, around 10k Da version: there is a Japanese version trade named Hyalo-Oligo that has only a 10k molecular weight and is claimed to penetrate the skin very well, have a unique touch and give deep and long-lasting moisturization. Based on the Evonik-research and the natural role of LMW-HA in the body working as a pro-inflammatory signal molecule, this ultra-low molecular weight version is a controversial ingredient

If you wanna become a real HA-and-the-skin expert, you can read much more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).

Glycine - goodie

A non-essential amino acid (the building blocks of skin proteins, like collagen or elastin), that the body can produce itself, but its production decreases with age. When you put it all over your face, it works as a moisturizer and maybe more. 

According to great skincare blog Futurederm, glycine might help with wound healing and tissue repair and when used together with other amino acids, leucine and proline it might improve wrinkles

BTW, it's also a building block of a bunch of important and famous peptides, including copper-tripeptide-1, palmitoyl tripeptide-1 or palmitoyl hexapeptide-12.

Alanine - goodie

A non-essential amino acid (a building block of skin proteins like collagen or elastin) that hydrates the skin.

What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It’s the - sodium form - cousin of the famous NMFhyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).

What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists. 

If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).

Serine - goodie

Serine is an amino acid that most often comes to the formula as part of a moisturizing complex. It's a non-essential amino acid (meaning that our body can synthesize it) and serves as a water-binding ingredient.

In general, amino acids are great skincare ingredients that play an important role in proper skin hydration but there is not much info out there about what specifically serine can do for the skin.

Valine - goodie

An essential amino acid (a building block of skin proteins like collagen) that our body cannot produce itself but has to take from external sources, like diet. 

It's a branched chain amino acid that is claimed to enhance energy, increase endurance and aid in muscle tissue recovery and repair when taken as a supplement. It's not clear what valine does when you put it on the skin, but as all amino acids, it must be at least a great skin hydrator.

Isoleucine - goodie

A branch-chained, essential amino acid that can be found in things like almond, cashew or soy protein. When taken orally it may promote protein synthesis. As for skincare - like all the amino acids - it's a skin-identical ingredient and moisturizer. It also seems to be useful as a barrier repair ingredient.  

Threonine - goodie

An essential amino acid that's also a key building block of collagen and elastin. When taken orally, it helps the digestive and intestinal tracts function more smoothly and also helps the absorption of nutrients. As for skincare, it is not clear what it does other than being a skin hydrator

Proline - goodie

A non-essential amino acid (meaning that our body can produce it) that's also one of the major building blocks of collagen. According to the Futurederm blog, it might be able to improve wrinkles when combined with other amino acids, glycine and leucine

Phenylalanine - goodie

An essential amino acid that the body cannot produce itself but has to take from the diet. Combined with UVA exposure, phenylalanine is used in the treatment of vitiligo (a pigmentation disorder where patches of the skin lose the pigment).

Histidine - goodie

A semi-essential amino acid meaning that enough has to be eaten from it so that the body does not use up essential amino acids (that our body cannot produce itself) to synthesize it. It has an important role in regulating the immune defense, allergic reactions, and inflammatory processes in the body.

As for skincare, it's a skin moisturizer that might also protect from some skin infections

Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.

It is typically used in tiny amounts, around 0.1% or less.

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does solvent | perfuming | viscosity controlling
A clear, colorless liquid that works as a solvent and viscosity decreasing ingredient. It also has great skin-moisturizing abilities.  [more]
what‑it‑does moisturizer/humectant | solvent | viscosity controlling
irritancy, com. 0, 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
what‑it‑does emollient
An emollient ester with a rich and creamy but non-greasy skin feel. [more]
what‑it‑does solvent
A multi-functional helper ingredient that acts as a humectant and emollient. It's also a solvent and can boost the effectiveness of preservatives. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
what‑it‑does cell-communicating ingredient | skin brightening | anti-acne | moisturizer/humectant
A multi-functional skincare superstar that has clinically proven anti-aging, skin lightening, anti-inflammatory and barrier repair properties. [more]
what‑it‑does moisturizer/humectant
A sugar beet derived amino acid derivative with nice skin protection and moisturization properties. Its special thing is being an osmolyte, a molecule that helps to control cell-water balance.  [more]
what‑it‑does preservative
It can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too. [more]
what‑it‑does antioxidant | emollient | perfuming
irritancy, com. 0, 0-2
Olive oil - an oleic acid-rich (55-83%) emollient plant oil that can moisturize dry skin. Also, it contains antioxidant polyphenols and vitamin E. [more]
what‑it‑does cell-communicating ingredient
An important compound in our body that has a vital cell-signalling role. It is wound healing, anti-inflammatory and can help with barrier repair. [more]
what‑it‑does antioxidant | emollient
Sea buckthorn berry oil - contains rare omega-7 fatty acid, antioxidants, and skin-soothing plant sterols. A nice moisturising and skin protecting oil. [more]
what‑it‑does perfuming
The essential oil coming from the flowers of Rose Geranium. Like most essential oils, it contains antioxidant and antimicrobial components, but the main ones are fragrant constituents. [more]
what‑it‑does viscosity controlling | emulsifying | surfactant/cleansing
A super commonly used thickener and emulsion stabilizer. [more]
what‑it‑does soothing | moisturizer/humectant
irritancy, com. 0, 0
Pro-Vitamin B5 is a goodie that moisturises the skin, has anti-inflammatory, skin protecting and wound healing properties. [more]
what‑it‑does perfuming
The essential oil coming from the rind of the orange. Its main component (83-97%) is limonene, the super common fragrant ingredient. [more]
what‑it‑does perfuming
The essential oil coming from steam distillation of freshly harvested, flowering peppermint sprigs. Its major component is menthol that gives the oil its well-known refreshing and cooling properties. [more]
what‑it‑does emollient
what‑it‑does perfuming
The essential oil coming from the fruit (probably the rind) of the bergamot orange.  It's a common top note in perfumes and contains (among others) fragrant compounds limonene (37%), linalyl acetate (30%) and linalool (8.8%).  A well-known issue with bergamot oil (apart from the fragrance allergens) is that it contains phototoxic  [more]
what‑it‑does soothing
The essential oil from the German Chamomile. It's loaded with the famous anti-inflammatory agent, bisabolol (about 50%). Used for its anti-inflammatory and soothing properties. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
A famous natural moisturizing factor that can bind up to 1000 times its own weight in water. Works as an excellent surface hydrator in skincare. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
It's an important skin-identical ingredient and great natural moisturizer that helps the skin to hold onto water and stay nicely hydrated. [more]
what‑it‑does buffering | moisturizer/humectant
The sodium salt of lactic acid. It's a great skin moisturizer and also used to regulate the pH value of the cosmetic formula. [more]
what‑it‑does emollient
The golden yellow oil coming from the Macadamia nut, a native Australian nut. Similar to other plant oils, it's loaded with emollient and nourishing fatty acids. [more]
what‑it‑does skin-identical ingredient
An amino acid that is one of the primary building blocks of hair keratin and skin collagen. It's a natural moisturizing factor and might also help to speed up wound healing.  [more]
what‑it‑does skin-identical ingredient
A non-essential amino acid  (important building block of collagen and elastin) that hydrates the skin. [more]
what‑it‑does emollient
what‑it‑does skin-identical ingredient | moisturizer/humectant
PCA stands for Pyrrolidone Carboxylic Acid and though it might not sound like it, it is a thing that can be found naturally in our skin. In fact, after amino acids, it is the second biggest NMF component of the skin with 12% being PCA of the NMF composition of normal skin.  So similar to other NMFs, it's a skin goodie that  [more]
what‑it‑does skin-identical ingredient
Ceramides make up 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated.  [more]
what‑it‑does skin-identical ingredient | emollient
irritancy, com. 0, 0
It's one of the important lipids that can be found naturally in the outer layer of the skin. About 25% of the goopy stuff between our skin cells consists of cholesterol. [more]
what‑it‑does emollient
A nourishing and moisturizing plant oil coming from the big, iconic Baobab tree. It's loaded with vitamin A, E, and D, as well as fatty acids (oleic 30-40%, linoleic 24-34%). [more]
what‑it‑does emollient | viscosity controlling
irritancy, com. 0, 2-3
A common multi-tasker fatty acid that works as an emollient, thickener and emulsion stabilizer. [more]
what‑it‑does antioxidant | emollient
irritancy, com. 0, 0-3
Avocado oil - a highly moisturizing, rich emollient oil that is loaded with fatty acids (oleic - 70%) and vitamin A, E and D. [more]
what‑it‑does skin-identical ingredient | cell-communicating ingredient | anti-acne | antimicrobial/antibacterial
A type of lipid that can be found naturally in the skin. Has antimicrobial and cell-communicating properties and is considered to be part of the skin's natural defence system. [more]
what‑it‑does moisturizer/humectant
Hydrolyzed Hyaluronic Acid is a low molecular weight, chemically chopped up version of the naturally big molecule and current IT-moisturizer, Hyaluronic Acid (HA). The TL; [more]
what‑it‑does skin-identical ingredient
An amino acid (the building blocks of skin proteins, like collagen) that hydrates the skin and might help wound healing and improve wrinkles. [more]
what‑it‑does skin-identical ingredient
A non-essential amino acid (a building block of skin proteins like collagen or elastin) that hydrates the skin.
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
what‑it‑does skin-identical ingredient
Serine is an amino acid that most often comes to the formula as part of a moisturizing complex. It's a non-essential amino acid (meaning that our body can synthesize it) and serves as a water-binding ingredient.In general, amino acids are great skincare ingredients that play an important role in proper skin hydration but there is not much info out there about what specifically serine can d [more]
what‑it‑does skin-identical ingredient
An essential amino acid (a building block of skin proteins like collagen) that is a skin hydrator. [more]
what‑it‑does skin-identical ingredient
An essential amino acid that hydrates the skin and might be also a barrier repair ingredient. [more]
what‑it‑does skin-identical ingredient
An essential amino acid (important building block of collagen and elastin) that hydrates the skin. [more]
what‑it‑does skin-identical ingredient
A non-essential amino acid (meaning that our body can produce it) that might be able to improve wrinkles combined with other amino acids, glycine and leucine. [more]
what‑it‑does skin-identical ingredient
An essential amino acid that is used in the treatment of vitiligo. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
An amino acid that is important in regulating the immune defense and inflammatory processes in the body. It's a skin moisturizer that might protect from skin infections. [more]
what‑it‑does chelating | viscosity controlling
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. [more]