Mesoprotech Melan 130+ Pigment Control Spf50+
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Mesoestetic Mesoprotech Melan 130+ Pigment Control Spf50+Ingredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
A clear, colorless, odorless oily liquid that makes the formula easily spreadable and also makes the skin nice and smooth (emollient). It's especially helpful in sunscreens as it can help to solubilize UV filters.
An oil-soluble chemical sunscreen agent that protects skin in the UVB and somewhat in the UVA II range with a peak absorption of 304 nm. Its protection is not strong enough on its own but it is quite photostable (loses 10% of SPF protection in 95 mins) and is often used to stabilize other photo-unstable UV-filters, for example, Avobenzone. It is also often used to improve the water resistance of the products.
Octocrylene's safety profile is generally quite good, though a review study in Contact Dermatitis reports an "increasing number of patients with photo contact allergy to octocrylene." Mainly adults with ketoprofen-sensitivity and children with sensitive skin are affected, so if you have a small kid, it is probably better to use octocrylene-free sunscreens.
A super commonly used 5 unit long, cyclic structured silicone that is water-thin and does not stay on the skin but evaporates from it (called volatile silicone). Similar to other silicones, it gives skin and hair a silky, smooth feel.
It's often combined with the non-volatile (i.e. stays on the skin) dimethicone as the two together form a water-resistant, breathable protective barrier on the skin without a negative tacky feel.
An oil-soluble chemical sunscreen agent that protects the skin from UVB (295-315 nm) with a peak protection at 306 nm. Homosalate is not a strong UV filter in and of itself (gives only SPF 4.3 protection at max. allowed 10% concentration) and it is not photostable (looses 10% of its SPF protection in 45 mins) so it always has to be combined with other sunscreens for proper protection. Its big advantage, though, is that it is a liquid and is excellent for dissolving other hard to solubilize powder sunscreen agents, like the famous Avobenzone.
Regarding Homosalate's safety profile, we do not have the best news. In-vitro (made in the labs) studies have shown that it might have some estrogenic activity. Do not panic, these studies were not conducted on real humans under real world conditions. Still, if you are a 'better safe than sorry' type, be careful when using Homosalate containing sunscreens long-term and full-body.
As of 2020, Homosalate is permitted to be used up to 10% in the EU and 15% in the US, but the EU is currently considering restricting it to only 1.4% (probably taking effect from 2022).
Its INCI name is a bit of a mouthful, but Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine is worth recognizing it as it is one of the best sunscreen agents known today. Unfortunately, it's not FDA-approved so you will not find it in sunscreens coming from the US (not because it's not good, but because US regulations make it impossible for newer sunscreen agents to get approved), but it is widely available in other parts of the world like Europe, Australia or Asia.
It is a broad-spectrum (covers the whole UVB and UVA range, 280-400 nm) chemical sunscreen agent with peak protections at about 310 and 345 nm and unlike older UV filters, it's very photostable. It hardly deteriorates in the presence of UV light and it's also useful in stabilizing other less stable sunscreen agents, like the famous UVA protector, avobenzone.
It's a new generation sunscreen agent that was specifically designed for high SPF and good UVA protection and based on a 2007 study that compared 18 sunscreen agents available in the EU it really had the best SPF protection (they used the highest concentration allowed by EU regulations from each 18 sunscreens and Trinosorb S gave an SPF 20 all by itself).
It is an oil-soluble, slightly yellowish powder that is not absorbed into the skin too much. This is good news for a sunscreen agent as it needs to be on the surface of the skin to do its job properly. Regarding Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine side effects, we have good news here as well: it has a great safety profile and unlike a couple of other chemical sunscreens, Trinosorb S (and M) does not show estrogenic activity.
Overall, we think Trinosorb S is one of the best sunscreen options available today.
Are you into sunscreen agents? We have shiny explanations (along with product lists) about others as well:
- Methylene Bis-Benzotriazolyl Tetramethylbutylphenol, aka Tinosorb M, the good buddy of our current molecule Tinosorb S
- Tris-Biphenyl Triazine, aka Tinosorb A2B, the newest addition to the Tinosorb family that protects strongly in an in-between wavelength that most other filters miss
- Ethylhexyl Triazone, aka Uvinul T 150, another new generation sunscreen agent with super-high UVB protection
- Diethylamino Hydroxybenzoyl Hexyl Benzoate, aka Uvinul A Plus, a new generation sunscreen for UVA protection
Simply alcohol refers to ethanol and it's a pretty controversial ingredient. It has many instant benefits: it's a great solvent, penetration enhancer, creates cosmetically elegant, light formulas, great astringent and antimicrobial. No wonder it's popular in toners and oily skin formulas.
The downside is that it can be very drying if it's in the first few ingredients on an ingredient list.
Some experts even think that regular exposure to alcohol damages skin barrier and causes inflammation though it's a debated opinion. If you wanna know more, we wrote a more detailed explanation about what's the deal with alcohol in skincare products at alcohol denat. (it's also alcohol, but with some additives to make sure no one drinks it).
The famous Avobenzone. It is a special snowflake as it is the only globally available chemical sunscreen agent that provides proper UVA protection (in the US, new generation sunscreen agents are not approved because of impossible FDA regulations). It is the global gold standard of UVA protection and is the most used UVA sunscreen in the world.
It gives very good protection across the whole UVA range (310-400 nm that is both UVA1 and UVA2) with a peak protection at 360 nm. The problem with it, though, is that it is not photostable and degrades in the sunlight. Wikipedia says that avobenzone loses 36% of its UV-absorption capacity after just one hour of sunlight (yep, this is one of the reasons why sunscreens have to be reapplied after a few hours).
The cosmetic's industry is trying to solve the problem by combining avobenzone with other UV filters that enhance its stability (like octocrylene, Tinosorb S or Ensulizole) or by encapsulating it and while both solutions help, neither is perfect. Interestingly, the combination of avobenzone with mineral sunscreens (that is titanium dioxide and zinc oxide) is not a good idea. In the US, it is flat out prohibited as avobenzone becomes unstable when combined with mineral sunscreens.
As for safety, avobenzone has a pretty good safety profile. It counts as non-irritating, and unlike some other chemical sunscreens, it shows no estrogenic effect. The maximum concentration of avobenzone permitted is 5% in the EU and 3% in the US.
Titanium Dioxide is one of the two members of the elite sunscreen group called physical sunscreens (or inorganic sunscreens if you’re a science geek and want to be precise).
Traditionally, UV-filters are categorized as either chemical or physical. The big difference is supposed to be that chemical agents absorb UV-light while physical agents reflect it like a bunch of mini umbrellas on top of the skin. While this categorization is easy and logical it turns out it's not true. A recent, 2016 study shows that inorganic sunscreens work mostly by absorption, just like chemical filters, and only a little bit by reflection (they do reflect the light in the visible spectrum, but mostly absorb in the UV spectrum).
Anyway, it doesn't matter if it reflects or absorbs, Titanium Dioxide is a pretty awesome sunscreen agent for two main reasons: it gives a nice broad spectrum coverage and it's highly stable. Its protection is very good between 290 - 350 nm (UVB and UVA II range), and less good at 350-400 nm (UVA I) range. Regular sized Titanium Dioxide also has a great safety profile, it's non-irritating and is pretty much free from any health concerns (like estrogenic effect worries with some chemical filters).
The disadvantage of Titanium Dioxide is that it's not cosmetically elegant, meaning it's a white, "unspreadable" mess. Sunscreens containing Titanium Dioxide are often hard to spread on the skin and they leave a disturbing whitish tint. The cosmetic industry is, of course, really trying to solve this problem and the best solution so far is using nanoparticles. The itsy-bitsy Nano-sized particles improve both spreadability and reduce the whitish tint a lot, but unfortunately, it also introduces new health concerns.
The main concern with nanoparticles is that they are so tiny that they are absorbed into the skin more than we want them (ideally sunscreen should remain on the surface of the skin). Once absorbed they might form unwanted complexes with proteins and they might promote the formation of evil free radicals. But do not panic, these are concerns under investigation. A 2009 review article about the safety of nanoparticles summarizes this, "to date, in-vivo and in-vitro studies have not demonstrated percutaneous penetration of nanosized particles in titanium dioxide and zinc oxide sunscreens". The English translation is, so far it looks like sunscreens with nanoparticles do stay on the surface of the skin where they should be.
All in all, Titanium Dioxide is a famous sunscreen agent and for good reason, it gives broad spectrum UV protection (best at UVB and UVA II), it's highly stable, and it has a good safety profile. It's definitely one of the best UV-filter agents we have today, especially in the US where new-generation Tinosorb filters are not (yet) approved.
The long name covers a nice sunscreen agent and quite a special one at that: It's a "hybrid" sunscreen meaning it's half-way between physical (the ones that, at least partly, reflect the sun) and chemical agents (that absorb the rays, which most sunscreens do). It is a new generation UV filter and, just like its sister, Trinosorb S, it is not available in the US.
It gives nice broad-spectrum coverage (280-400 nm, meaning UVB as well as UVA protecion) with peak protection at 305 nm and 360 nm and it is highly photostable. It can also help to stabilize other less stable sunscreens, like Octinoxate and is generally happy to work together with other UV-filters.
Its hybrid nature means that it is organic like the chemical agents, but it is neither water nor oil soluble and works as a suspension of micro fine particles. If the small particles scare you, we have good news: the safety profile of Tinosorb M is great. It is not absorbed into the skin and unlike some other chemical sunscreens, it does not show estrogenic activity.
The downside of its hybrid nature is that - similar to the inorganic sunscreens zinc and titanium dioxide - Tinosorb M also leaves a white cast on the skin that can be bothersome on darker skin tones.
A light-feeling, volatile (meaning it does not absorb into the skin but evaporates from it) silicone that gives skin a unique, silky and non-greasy feel. It has excellent spreading properties and leaves no oily residue or build-up.
PEG-30 Dipolyhydroxystearate is a popular water-in-oil (w/o) emulsifier, meaning that it helps the oily and watery parts of the formula to mix in a way where water droplets are dispersed in the continuous oil phase and not the other way round.
Compared to the more commonly used oil-in-water (o/w) emulsions, w/o emulsions tend to be heavier and less cosmetically elegant, but PEG-30 Dipolyhydroxystearate is claimed to help with this and enables a light and elegant skin feel. It also has a molecular structure that creates large anchors both in the water and in the oil phase making the resulting emulsion not only cosmetically elegant but also very stable.
A silicone-based, chemical sunscreen agent that protects the skin in the UVB range (290-320 nm) with a peak absorbance at 312 nm. It is a colorless to pale yellow liquid with nice and non-shiny (at least compared to most other sunscreens) sensorial properties.
It is a pretty good team player and can stabilize the famously unstable UVA filter, avobenzone and works especially well with Ensulizole to achieve high SPF protection. It is approved up to 10% as a sunscreen filter in the EU and most parts of the world, except for the United States.
A film-forming polymer (big molecule from repeated subunits) to create water-resistant sunscreen formulas. It also improves the SPF value of sunscreen formulas (approx. 11-18% boost in SPF per 1% Styrene/Acrylates Copolymer).
A silicone emulsifier that helps water and silicone oils to mix nicely together. It can also be used together with plant oil + silicone oil mixtures.
A white powdery thing that's the major component of glass and sand. In cosmetics, it’s often in products that are supposed to keep your skin matte as it has great oil-absorbing abilities. It’s also used as a helper ingredient to thicken up products or suspend insoluble particles.
A clear, colorless liquid that gives advanced protection for the skin lipids and truly photostabilizes UV filters, at least according to its manufacturer. It's as effective of an antioxidant as pure Vitamin E, aka tocopherol and as stable as its esterified version tocopheryl acetate.
It's claimed to efficiently and continuously work over 24 hours by a continuous three-phase mechanism: it dims oxidative stress, builds up protection from ROS (evil free radicals) and prevents the formation of further reactive species.
If that would not be enough, it also seems to be a promising ingredient for acne prevention. In an in-vivo test on 22 volunteers, a 2% Bis-Ethylhexyl Hydroxydimethoxy Benzylmalonate formula decreased skin oiliness by 20% after 8 weeks of treatment, and skin inflammation and redness also improved by 25%.
We don't have description for this ingredient yet.
A derivative of clinically proven, superstar ingredient Azelaic Acid and hydrating amino acid Glycine. Azelaic acid is an awesome ingredient with anti-inflammatory, skin lightening and anti-acne effects, but its insolubility (it's soluble neither in water nor in oil) makes it difficult to use it in a cosmetically elegant and versatile way.
The solution is supposed to be Potassium Azeloyl Diglycinate, at least according to the manufacturer. The derivative is very water soluble, easy to use in nice formulas and inherits all the lovely properties of Azelaic acid. It acts as a skin brightening agent via Tyrosinase (a famous enzyme needed to make melanin) inhibition and also has significant sebum normalizing activity.
Regarding research, we could find two studies where Potassium Azeloyl Diglycinate's name popped up. One study examined the management of rosacea and the other one researched the treatment of melasma. Both were successful (we mean people showed improvement :)) but our Azelaic acid derivative was combined with other actives so it's hard to know what to attribute to this guy only.
Overall, a promising multi-function active that's worth checking out if you have pigmentation-prone, acne-prone or rosacea-prone skin.
Jojoba-derived emollient wax esters (fatty acid + fatty alcohol) that make your skin feel nice and smooth. Chemically speaking, pure jojoba oil is also a wax ester (read our shiny explanation here), however, the ingredients called jojoba esters on the ingredient lists are made from jojoba oil and/or hydrogenated jojoba oil via interesterification.
They have multiple versions with variable fatty acid chain length and the ingredient can have a liquid, a creamy, a soft or firm paste, or even a hard wax consistency. The common thing between all versions is, that unlike most normal triglyceride oils, jojoba esters have superior stability, provide non-greasy emolliency and are readily absorbed into the skin.
A fast spreading emollient ester (hexyl alcohol + lauric acid) that's used in water in oil emulsions or in water-free formulas. It gives a light skin feel.
Sunflower does not need a big intro as you probably use it in the kitchen as cooking oil, or you munch on the seeds as a healthy snack or you adore its big, beautiful yellow flower during the summer - or you do all of these and probably even more. And by even more we mean putting it all over your face as sunflower oil is one of the most commonly used plant oils in skincare.
It’s a real oldie: expressed directly from the seeds, the oil is used not for hundreds but thousands of years. According to The National Sunflower Association, there is evidence that both the plant and its oil were used by American Indians in the area of Arizona and New Mexico about 3000 BC. Do the math: it's more than 5000 years – definitely an oldie.
Our intro did get pretty big after all (sorry for that), so let's get to the point finally: sunflower oil - similar to other plant oils - is a great emollient that makes the skin smooth and nice and helps to keep it hydrated. It also protects the surface of the skin and enhances the damaged or irritated skin barrier. Leslie Bauman notes in Cosmetic Dermatology that one application of sunflower oil significantly speeds up the recovery of the skin barrier within an hour and sustains the results 5 hours after using it.
It's also loaded with fatty acids (mostly linoleic (50-74%) and oleic (14-35%)). The unrefined version (be sure to use that on your skin!) is especially high in linoleic acid that is great even for acne-prone skin. Its comedogen index is 0, meaning that it's pretty much an all skin-type oil.
Truth be told, there are many great plant oils and sunflower oil is definitely one of them.
Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.
As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity.
As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types).
If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.
Also, it's an effective deodorant and a medium spreading emollient.
The flower wax coming from Mimosa that has nice skin protecting and film-forming properties. It also has a nice, sweet smell well known to perfumers.
Mimosa wax often comes to the formula together with sunflower and jojoba waxes as the three of them is trade named Acticire and form a natural texture agent that works both as an emollient bringing softness to the formula as well as an active ingredient with skin-repairing, protecting, and moisturizing properties.
Three glycerin molecules attached together. It is a humectant and moisturizer ingredient just like glycerin, but the larger molecular structure penetrates slower into the skin and gives milder, longer lasting moisture.
We don't have description for this ingredient yet.
A silicone emulsifier that helps water and silicone oils to mix nicely together.
We don't have description for this ingredient yet.
Sodium chloride is the fancy name of salt. Normal, everyday table salt.
If (similar to us) you are in the weird habit of reading the label on your shower gel while taking a shower, you might have noticed that sodium chloride is almost always on the ingredient list. The reason for this is that salt acts as a fantastic thickener in cleansing formulas created with ionic cleansing agents (aka surfactants) such as Sodium Laureth Sulfate. A couple of percents (typically 1-3%) turns a runny surfactant solution into a nice gel texture.
If you are into chemistry (if not, we understand, just skip this paragraph), the reason is that electrolytes (you know, the Na+ and Cl- ions) screen the electrostatic repulsion between the head groups of ionic surfactants and thus support the formation of long shaped micelles (instead of spherical ones) that entangle like spaghetti, and viola, a gel is formed. However, too much of it causes the phenomenon called "salting out", and the surfactant solution goes runny again.
Other than that, salt also works as an emulsion stabilizer in water-in-oil emulsions, that is when water droplets are dispersed in the outer oil (or silicone) phase. And last but not least, when salt is right at the first spot of the ingredient list (and is not dissolved), the product is usually a body scrub where salt is the physical exfoliating agent.
We don't have description for this ingredient yet.
A vegetable origin (coconut or palm kernel oil and glucose) cleansing agent with great foaming abilities. It's also mild to the skin and readily biodegradable.
An organic derivative of hectorite clay, Disteardimonium Hectorite is used as a viscosity controller - it thickens up formulations to make them less runny.
It’s most popular use in cosmetics is in sunscreens, under the trademarked name Bentone 38 from Elementis. According to the manufacturer info, it is a real multi-tasker, including the ability to prevent pigments settling during storage, stabilizing a formula for longer, creating a light and smooth skin feel and enhancing the water-resistance of sunscreen formulas.
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
It is typically used in tiny amounts, around 0.1% or less.
We don't have description for this ingredient yet.
It's the chemically chopped up version of normal lecithin. Most often it's used to create liposomes and to coat and stabilize other ingredients.
- It's a helper ingredient that improves the freeze-thaw stability of products
- It's also a solvent, humectant and to some extent a penetration enhancer
- It has a bad reputation among natural cosmetics advocates but cosmetic scientists and toxicology experts do not agree (read more in the geeky details section)
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate is an antioxidant molecule used in small amounts (less than 0.8%) to help products stay nice longer. More specifically, it is great at preventing discoloration or other types of oxidative degradation. It is a trendy alternative to often bad-mouthed synthetic antioxidant and stabilizer, BHT.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!).
If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.
Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!).
Yellow Iron Oxide is the super common inorganic (as in no carbon atom in the molecule) pigment that gives the yellow tones in your foundation. Blended with red and black iron oxides, it is essential in all "flesh-toned" makeup products.
Chemically speaking, it is hydrated iron III oxide and depending on the conditions of manufacture, it can range from a light lemon to an orange-yellow shade.
Red Iron Oxide is the super common pigment that gives the familiar, "rust" red color. It is also the one that gives the pink tones in your foundation. Chemically speaking, it is iron III oxide (Fe2O3).
Black Iron Oxide is the super common inorganic (as in no carbon atom in the molecule) pigment that controls the darkness of your foundation or gives the blackness to your mascara. Blended with red and black iron oxides, it is essential in all "flesh-toned" makeup products.
Chemically speaking, it is a mixture of iron II and iron III oxide. Btw, this guy, unlike the yellow and red pigments, is magnetic.
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| what‑it‑does | solvent |
| what‑it‑does | emollient | solvent |
| what‑it‑does | sunscreen |
| what‑it‑does | emollient | solvent |
| what‑it‑does | sunscreen |
| what‑it‑does | sunscreen |
| what‑it‑does | antimicrobial/antibacterial | solvent | viscosity controlling |
| what‑it‑does | sunscreen |
| what‑it‑does | sunscreen | colorant |
| what‑it‑does | sunscreen |
| what‑it‑does | emollient | solvent |
| what‑it‑does | emulsifying |
| what‑it‑does | sunscreen |
| what‑it‑does | emulsifying |
| what‑it‑does | viscosity controlling |
| what‑it‑does | antioxidant |
| what‑it‑does | skin brightening | anti-acne | soothing |
| what‑it‑does | soothing | emollient | moisturizer/humectant |
| what‑it‑does | emollient |
| what‑it‑does | emollient |
| irritancy, com. | 0, 0 |
| what‑it‑does | emollient |
| irritancy, com. | 0, 1 |
| what‑it‑does | preservative |
| what‑it‑does | emollient |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | emulsifying |
| what‑it‑does | viscosity controlling |
| what‑it‑does | viscosity controlling |
| what‑it‑does | surfactant/cleansing |
| what‑it‑does | viscosity controlling |
| what‑it‑does | chelating |
| what‑it‑does | emollient | emulsifying |
| what‑it‑does | moisturizer/humectant | solvent | viscosity controlling |
| irritancy, com. | 0, 0 |
| what‑it‑does | viscosity controlling |
| what‑it‑does | antioxidant | preservative |
| what‑it‑does | preservative |
| what‑it‑does | perfuming |
| what‑it‑does | colorant |
| irritancy, com. | 0, 0 |
| what‑it‑does | colorant |
| irritancy, com. | 0, 0 |
| what‑it‑does | colorant |
| irritancy, com. | 0, 0 |