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Potassium Azeloyl Diglycinate

Potassium Azeloyl Diglycinate



A derivative of clinically proven, superstar ingredient Azelaic Acid and hydrating amino acid Glycine. Azelaic acid is an awesome ingredient with anti-inflammatory, skin lightening and anti-acne effects, but its insolubility (it's soluble neither in water nor in oil) makes it difficult to use it in a cosmetically elegant and versatile way. 

The solution is supposed to be Potassium Azeloyl Diglycinate, at least according to the manufacturer. The derivative is very water soluble, easy to use in nice formulas and inherits all the lovely properties of Azelaic acid. It acts as a skin brightening agent via Tyrosinase (a famous enzyme needed to make melanin) inhibition and also has significant sebum normalizing activity. 

Regarding research, we could find two studies where Potassium Azeloyl Diglycinate's name popped up. One study examined the management of rosacea and the other one researched the treatment of melasma. Both were successful (we mean people showed improvement :)) but our Azelaic acid derivative was combined with other actives so it's hard to know what to attribute to this guy only. 

Overall, a promising multi-function active that's worth checking out if you have pigmentation-prone, acne-prone or rosacea-prone skin.

Show me some proof

  • Berardesca, Enzo, et al. "Clinical and instrumental assessment of the effects of a new product based on hydroxypropyl chitosan and potassium azeloyl diglycinate in the management of rosacea." Journal of cosmetic dermatology 11.1 (2012): 37-41.
  • Viyoch, Jarupa, et al. "Effects of trans-4-(aminomethyl) cyclohexanecarboxylic acid/potassium azeloyl diglycinate/niacinamide topical emulsion in Thai adults with melasma: a single-center, randomized, double-blind, controlled study." Current Therapeutic Research 71.6 (2010): 345-359.
  • Veraldi, Stefano, et al. "Treatment of symptoms of erythemato-telangiectatic rosacea with topical potassium azeloyl diglycinate and hydroxypropyl chitosan: Results of a sponsor-free, multicenter, open study." Journal of Dermatological Treatment 26.2 (2015): 191-192.

Products with a known amount of Potassium Azeloyl Diglycinate

Other products with Potassium Azeloyl Diglycinate

CCSD Rx Brightening Cream e'clat superior Acne Edit – Acne Cleansing Face Wash Avoskin Your Skin Bae Azeclair 10% + Kombucha 3% + Niacinamide 2,5% Vaccine Serum Avoskin Your Skin Bae Azeclair 10% + Kombucha 3% + Niacinamide 2,5% Vaccine Serum Azelique Age Refining Pycnogenol Cream Be Minimalist Minimalist Azeclair 17% + Propolis Bimaio Matte Rescue Ampoule Boots Dermacare Rosacea Treatment Serum Boots Laboratories No7 Derm Solutions Rosacea Treatment CERAGLOW Nuuha Brightening Serum Deconstruct Breakout Control D.s. Serum - 5% Succinic Acid + 8% Pad (Potassium Azeloyl Diglycinate) DermoFuture Normalizing Moisturizing Elixir Dr. Medica Dermatological Anti-Acne Face Serum Ellana Mineral Cosmetics Clear Skin+ Clarifying Serum With 10% Azelaic Acid Elyn’s Lab Acne Care Face Mask Base GH Gema Herrerias 12-Azelaic-N Garden of Wisdom Azelaic Acid 12% Serum (PAD) Garden of Wisdom Azelaic Acid Serum 8% Garden of Wisdom Azeloyl Glycine Serum Geek & Gorgeous aPad 20% Azelaic Acid Derivative Serum Glowing Essence Complete Serum Hedonia 20% (azelaic) Pad+ 5% Panthenol Serum Helia-D Cell Concept Lightening Serum Helia-D Cell Concept Regenerating Serum Helia-D Professional Brightening Serum Kaya Brightening Night Cream Kaya Pigmentation Reducing Complex - Night Cream KisoCare 15% Azelaic Acid Serum Mineraline Spot Treatment Gel Miya Cosmetics Soro Para Problemas De Pele Beauty.Lab Novaclear Whiten Advanced Whitening Serum Novaclear Whiten Whitening Face Mist OMNISKIN Watermelon Glow Serum Pharmaclinix Lightenex Gold Serum Roydermal Benzo 3 SKINMADE AZ & Salicylic Acid + Licorice Root Serum Skin Actives T-Zone Serum Snow Fox Skincare True Luminosity Serum Umoua Anti-Acne Gel Weeduri Multibright Dark Spot Serum doa kozmetik Gözaltı Bakım Kremi doa kozmetik Kızarıklık Karşıtı Krem doa kozmetik Leke Karşıtı Krem doa kozmetik Leke Karşıtı Krem the Cocoon Winter Melon Acne Drops the bath box Kombucha Gentle Multi-acid Toner the formula rx Azelaic Acid Serum- Potassium Azeloyl Diglycinate 20% +FUL Niacinamide 10% Serum (anti-blemish Brightening Treatment) +FUL Niacinamide 5% Serum (for Sensitive Skin) Acnemy Postzit Serum