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Potassium Azeloyl Diglycinate

Potassium Azeloyl Diglycinate


Official CosIng Information


A derivative of clinically proven, superstar ingredient Azelaic Acid and hydrating amino acid Glycine. Azelaic acid is an awesome ingredient with anti-inflammatory, skin lightening and anti-acne effects, but its insolubility (it's soluble neither in water nor in oil) makes it difficult to use it in a cosmetically elegant and versatile way. 

The solution is supposed to be Potassium Azeloyl Diglycinate, at least according to the manufacturer. The derivative is very water soluble, easy to use in nice formulas and inherits all the lovely properties of Azelaic acid. It acts as a skin brightening agent via Tyrosinase (a famous enzyme needed to make melanin) inhibition and also has significant sebum normalizing activity. 

Regarding research, we could find two studies where Potassium Azeloyl Diglycinate's name popped up. One study examined the management of rosacea and the other one researched the treatment of melasma. Both were successful (we mean people showed improvement :)) but our Azelaic acid derivative was combined with other actives so it's hard to know what to attribute to this guy only. 

Overall, a promising multi-function active that's worth checking out if you have pigmentation-prone, acne-prone or rosacea-prone skin.

Show me some proof

  • Berardesca, Enzo, et al. "Clinical and instrumental assessment of the effects of a new product based on hydroxypropyl chitosan and potassium azeloyl diglycinate in the management of rosacea." Journal of cosmetic dermatology 11.1 (2012): 37-41.
  • Viyoch, Jarupa, et al. "Effects of trans-4-(aminomethyl) cyclohexanecarboxylic acid/potassium azeloyl diglycinate/niacinamide topical emulsion in Thai adults with melasma: a single-center, randomized, double-blind, controlled study." Current Therapeutic Research 71.6 (2010): 345-359.
  • Veraldi, Stefano, et al. "Treatment of symptoms of erythemato-telangiectatic rosacea with topical potassium azeloyl diglycinate and hydroxypropyl chitosan: Results of a sponsor-free, multicenter, open study." Journal of Dermatological Treatment 26.2 (2015): 191-192.

Products with a known amount of Potassium Azeloyl Diglycinate

Other products with Potassium Azeloyl Diglycinate

Azelique Age Refining Pycnogenol Cream Dr. Medica Dermatological Anti-Acne Face Serum Garden of Wisdom Azelaic Acid 12% Serum (PAD) Garden of Wisdom Azelaic Acid Serum 8% Garden of Wisdom Azeloyl Glycine Serum Geek & Gorgeous Apad 20% Azelaic Acid Derivative Serum Mineraline Spot Treatment Gel Novaclear Whiten Advanced Whitening Serum Pharmaclinix Lightenex Gold Serum Skin Actives T-Zone Serum Umoua Anti-Acne Gel Bielenda Zielona Herbata Serum (Green Tea) Consult Beauté Champagne Beauté Facial Concentrate For Beloved One 7% Mandelic Acid + Azelaic Acid Gentle Renewing Brightening Peel Lamelle Clarity Corrective Am Sesderma Azelac Moisturizing Cream Tinkerskin Azelaic Glycine + Chamomile + Mandelic Acid Clarifying Toner Uncover Skincare Azelaic Acid Serum [ten.twelve] skincare Pines & Purity Clarifying Serum naturium AZELAIC TOPICAL ACID 10% Allies of Skin Promise Keeper Blemish Sleeping Facial Allies of Skin Promise Keeper™ Blemish Facial Colleen Rothschild Skincare Mandelic Acid Radiance Serum Defensil Pimple Defense Soap Dr. Brandt Skincare Dark Spots No More® Triple Acid Spot Minimizing Concentrate IdealDerm Rosa Gel Plenaire Violet Paste RESIBO Normalizing Serum. Sebum Control + Imperfections Serious Skincare Ultra-Mare Pure Marine Infusion Concentrated Treatment Pads Ahava Age Control Even Tone & Brightening Sheet Mask Dr Dennis Gross Ferulic Acid + Retinol Brightening Solution ETVOS Acne Vc Cream Gel Flawless Pimple Astringent HighDroxy Porify Solution Lamelle Clarity Active Control Lumière de Vie Lumière de Vie® Super Crème NIOD Re: Pigment REN Ready Steady Glow Daily Aha Tonic Skintegra Infrared Aisuanis Energy Complex Ahas Exfoliating Toner BE.LOVED Fruits&Flowers Hidden Powers Toner With Aha Acids Dr. Medica Dermatological Anti-Acne Face Cream Revolution Skincare Oily Skin Intense Peeling Solution Sesderma Sensyses Cleanser - Lightening Yamuna Stop!Acne Gel For Acne Allies of Skin Promise Keeper™ Blemish Sleeping Facial Azelique Age Refining Day Lotion, With Azelaic Acid Azelique Age Refining Night Cream Farsali Liquid Powder Oil Balancing Serum Glowbiotics Instant Resurfacing Pads