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ISDIN Isdinceutics Age Reverse

Isdinceutics Age Reverse

Protects the skin from pollution with Exo-P. Moisturises and remodels the contours of the face with reticulated hyaluronic acid and Syn-Hycan. Slows the formation of AGEs with Carnosine
Uploaded by: saramar on 20/06/2019

Highlights

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Ingredient name what-it-does irr., com. ID-Rating
Aqua (Water) solvent
Butylene Glycol moisturizer/​humectant, solvent 0, 1
Isodecyl Neopentanoate emollient
Propanediol solvent, moisturizer/​humectant
Niacinamide cell-communicating ingredient, skin brightening, anti-acne, moisturizer/​humectant superstar
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Betaine moisturizer/​humectant goodie
Caprylic/Capric Triglyceride emollient
Silica viscosity controlling
Dimethicone emollient 0, 1
Hydrogenated Polyisobutene emollient 2, 1
Stearyl Alcohol emollient, viscosity controlling 2, 2
Octyldodecanol emollient
Dipentaerythrityl Hexacaprylate/Hexacaprate emollient
Tridecyl Trimellitate emollient
Phenylpropanol perfuming, solvent
Ammonium Acryloyldimethyltaurate/VP Copolymer viscosity controlling
Acrylates/C10-30 Alkyl Acrylate Crosspolymer viscosity controlling
Caprylyl Glycol moisturizer/​humectant, emollient
Parfum (Fragrance) perfuming icky
Cetearyl Alcohol emollient, viscosity controlling 1, 2
Potassium Olivoyl Hydrolyzed Oat Protein surfactant/​cleansing
Glyceryl Stearate emollient, emulsifying 0, 1-2
Carnosine antioxidant, cell-communicating ingredient goodie
Tridecyl Stearate emollient
Neopentyl Glycol Dicaprylate/Dicaprate emollient
Glyceryl Oleate emollient, emulsifying
Pentylene Glycol solvent, moisturizer/​humectant
Sodium Hyaluronate Crosspolymer skin-identical ingredient, antioxidant, moisturizer/​humectant goodie
Disodium EDTA chelating
PEG-8 moisturizer/​humectant, solvent
Alteromonas Ferment Extract soothing goodie
Hydroxypropyl Cyclodextrin goodie
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate cell-communicating ingredient goodie
Tocopherol antioxidant 0-3, 0-3 goodie
Benzyl Alcohol preservative, perfuming, solvent, viscosity controlling
Potassium Sorbate preservative
Sodium Benzoate preservative
Ascorbyl Palmitate antioxidant 0, 2 icky
Magnesium Chloride viscosity controlling
Alcohol Denat antimicrobial/​antibacterial, solvent, viscosity controlling icky
Ascorbic Acid antioxidant, skin brightening superstar
Citric Acid exfoliant, buffering goodie
Palmitoyl Tripeptide-38 cell-communicating ingredient goodie
Ci 15985 (Yellow 6) colorant
Ci 19140 (Yellow 5) colorant

ISDIN Isdinceutics Age Reverse
Ingredients explained

Also-called: Water | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

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It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive. 

What-it-does: emollient

A  low molecular weight dry, silky emollient ester that gives a light and non-greasy feel to the formulas. It's great at reducing the oily or heavy feeling caused by certain ingredients such as sunscreen agents or pigments. It also gives improved emolliency, spreadability and a smooth, elegant feel on the skin.

Also-called: Zemea | What-it-does: solvent, moisturizer/humectant

Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved. 

It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. 

Niacinamide - superstar
Also-called: vitamin B3, nicotinamide | What-it-does: cell-communicating ingredient, skin brightening, anti-acne, moisturizer/humectant
  • A multi-functional skincare superstar with several proven benefits for the skin
  • Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
  • Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
  • Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
  • Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
Read all the geeky details about Niacinamide here >>

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot)
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

Betaine - goodie
What-it-does: moisturizer/humectant

A sugar beet derived amino acid derivative with nice skin protection and moisturization properties. Betain's special thing is being an osmolyte, a molecule that helps to control cell-water balance.  It is also a natural osmoprotectant, meaning that it attracts water away from the protein surface and thus protects them from denaturation and increases their thermodynamic stability. 

It also gives sensorial benefits to the formula and when used in cleansers, it helps to make them milder and gentler. 

What-it-does: emollient

A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, and it’s also easy to formulate with. No wonder it’s popular. 

A white powdery thing that's the major component of glass and sand. In cosmetics, it’s often in products that are supposed to keep your skin matte as it has great oil-absorbing abilities. It’s also used as a helper ingredient to thicken up products or suspend insoluble particles. 

What-it-does: emollient | Irritancy: 0 | Comedogenicity: 1

Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.

As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity. 

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As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types). 

What-it-does: emollient | Irritancy: 2 | Comedogenicity: 1

A synthetic liquid oil that can replace mineral oil or silicone oils in the cosmetic formulas. There are different grades depending on the molecular weight ranging from very light, volatile, non-residue leaving ones to more substantial, slight residue leaving ones.

Apart from leaving the skin soft and smooth (emollient), it's also used as a waterproofing agent in sunscreens or makeup products and as a shine enhancer in lip gloss formulas. 

What-it-does: emollient, viscosity controlling, emulsion stabilising | Irritancy: 2 | Comedogenicity: 2

A handy multi-tasker, white to light yellowish oil-loving wax that works very well in oil-in-water emulsions.  It makes your skin feel nice and smooth (emollient),  stabilizes oil-water mixes and gives body to them.

Oh, and one more thing: it's a so-called fatty alcohol - the good, emollient type of alcohol that is non-drying and non-irritating. It is often mixed with fellow fatty alcohol, Cetyl Alcohol, and the mixture is called Cetearyl Alcohol in the ingredient list. 

What-it-does: emollient

A clear, slightly yellow, odorless oil  that's a very common, medium-spreading emollient. It makes the skin feel nice and smooth and works in a wide range of formulas.

What-it-does: emollient

A medium viscosity, odorless oily liquid that leaves an excellent afterfeel, with the skin feeling soft and conditioned. The feel is described by the manufacturer as slightly oily but not tacky or sticky.

Dipentaerythrityl Hexacaprylate/Hexacaprate often comes to the formula mixed with two other emollients, Tridecyl Stearate, and Tridecyl Trimellitate, as the trio can match the aesthetic and textural properties of ruined-by-natural-marketers mineral oil.

What-it-does: emollient

A viscous, thick liquid emollient that gives lubricity and cushion at low use levels. It's great for night creams, eye area products, and skin treatment products due to the substantive film forming ability. 

What-it-does: perfuming, solvent

A naturally occurring floral component with a delicate scent that can mask the odor of other raw materials but is not noticeable in the final product. It also has remarkable antimicrobial and preservative boosting abilities and can help to create "preservative-free" formulas.

Also-called: Aristoflex AVC | What-it-does: viscosity controlling

A kind of polymer (big molecule from repeated subunits) that helps to create beautiful gel-like textures. It's also a texturizer and thickener for oil-in-water emulsions. It gives products a good skin feel and does not make the formula tacky or sticky. 

It works over a wide pH range and is used between 0.5-1.2%.

Though its long name does not reveal it, this polymer molecule (big molecule from repeated subunits or monomers) is a relative to the super common, water-loving thickener, Carbomer. Both of them are big molecules that contain acrylic acid units, but Acrylates/C10-30 Alkyl Acrylate Crosspolymer also contains some other monomers that are hydrophobic, i.e. water-hating. 

This means that our molecule is part water- and part oil-loving, so it not only works as a thickener but also as an emulsion stabilizer. It is very common in gel-type formulas that also contain an oil-phase as well as in cleansers as it also works with most cleansing agents (unlike a lot of other thickeners). 

It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol

The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.

Also-called: Fragrance, Parfum;Parfum/Fragrance | What-it-does: perfuming

Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!). 

If you are someone who likes to know what you put on your face than fragrance is not your best friend - no way to know what’s really in it.  

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Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!). 

What-it-does: emollient, viscosity controlling | Irritancy: 1 | Comedogenicity: 2

An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.  

It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols.  Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.

What-it-does: surfactant/cleansing

We don't have description for this ingredient yet.

What-it-does: emollient, emulsifying | Irritancy: 0 | Comedogenicity: 1-2

A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.

Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.

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It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".

Carnosine - goodie

Though its name does not reveal it, Carnosine is a peptide, a small, two amino acid (β-Ala-His) one. It is naturally present in high concentrations in muscle and brain tissues, but the one used in cosmetic products is biomimetic, meaning that it is synthetically produced in a lab to copy the natural thing. 

A 2017 review paper on topical peptides writes about Carnosine that it is a "well-documented aqueous antioxidant with wound healing activity".  

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Other than that we can write about manufacturer-done in-vitro (in the lab, not on real people) studies that show Carnosine to have anti-glycation properties. Glycation is the not-so-nice process that happens when we bombard our body with too much sugar that results in damaged body proteins and eventually in more wrinkles.  

Also, a manufacturer done in vitro study shows that carnosine might have collagen-boosing magic power. However, the 2017 research paper also mentions that even though Carnosine is a small molecule, it is water soluble and does not penetrate the skin past the top layers so we have some doubt if the collagen-boosting works in real life. We could find one anti-aging study made on real people that mentions Carnosine, but it was combined with a bunch of other anti-aging actives so it is pretty much impossible to know what Carnosine did or did not. 

One last thing to mention is that there is also a manufacturer done clinical study (done on real people) that shows carnosine being effective against the damages caused by infrared (IR) radiation. (source)

What-it-does: emollient

A clear, colorless oily liquid that works as a medium feel emollient. It absorbs very quickly into the skin, leaves no shine and gives a nice, velvety after-feel.

What-it-does: emollient

An emollient ester (basically an oil like liquid) with a light, elegant and silky feel. It gives a matte finish to the products.

It often comes together with two other esters (called Tridecyl Stearate and Tridecyl Trimellitate) as the three of them can be blended so that they mimic very closely the aesthetic and textural properties of controversial, but nice feeling mineral oil.

What-it-does: emollient, emulsifying

The attachment of glycerin and oleic acid that works mainly as a co-emulsifier and stabilizer to create stable water-oil mixes, aka emulsions. It is also popular in cleansing products as it helps to thicken them up and has some refatting and skin-smoothing effect. 

A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent and a broad spectrum antimicrobial. According to manufacturer info, it's also a moisturizer and helps to make the product feel great on the skin. It works synergistically with preservatives and helps to improve water-resistance of sunscreens. 

It's a special "cross-linked" from of IT-moisturizer, hyaluronic acid (HA). Cross-linked means that "normal" HA pieces (1-2 million Da molecular weight) are chemically bound togeather to create a big, "infinite" mesh.

The special HA mesh has a remarkable water-binding capacity, 5 times more than the already crazy water-binding capacity of "normal" HA. This water filled crosslinked HA gel forms a smooth film on the skin and continuously delivers the bound water, so it gives long-term moisturizing benefits.

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Btw, crosslinking HA was developed for dermal fillers (as crosslinking helps their longevity), and this guy is the topical version of FDA approved dermal filler called Hylan B gel. Smearing crosslinked version all over ourselves is a newish thing, and incoming evidence so far suggests that it's a great idea, even better than normal HA. 

A very recent, 2016 research article compared the topical moisturizing effect of crosslinked HA (not Hylan B gel specifically, but something called Resilient HA or RHA), HMW-HA and LMW-HA and found that "TEWL (that is trans-epidermal water loss, the water that evaporates from the skin) was reduced by 27.8% with RHA, and by 15.6% with HMW HA, but increased by 55.5% with LMW HA." (You can read much more about HMW and LMW HA here in the geeky details section.)

All in all, we think Sodium Hyaluronate Crosspolymer is an awesome version of HA, probably superior to traditional versions, so be happy to spot it on the ingredient list. 

What-it-does: chelating

Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.

A smallish polymer molecule (created from repeated units of Polyethylene glycol, aka PEG) that's used as a solubilizer and viscosity control agent.

It is a clear, colorless liquid that is water-soluble and water-binding (aka humectant) and can help to solubilize sparingly-water soluble things (e.g. vanilla, perfumes) into water-based formulas. Thanks to its water-binding ability, it also prevents the drying out of formulas, especially when combined with the fellow hygroscopic agent, sorbitol

What-it-does: soothing

A so-called exopolysaccharide (high-molecular-weight polymers) secreted by a microorganism living in hydrothermal deep vents. The manufacturer claims that it soothes and reduces irritation to sensitive skin against chemical (such as drying acne treatments or strong chemical exfoliants), mechanical (such as micro-cuts after shaving) and UVB aggressors.

It goes by the trade name "Phytodermina Lifting" that refers to two things: it's a "lifting" ingredient and it comes from plant raw materials. 

The manufacturer claims that it gives the skin a marked lifting effect, moisturizes, makes the skin soft and smooth, enhances brightness, and helps make-up to stay on after application.

Also-called: SYN-HYCAN | What-it-does: cell-communicating ingredient

A small, three amino acid synthetic tripeptide with a molecular weight smaller than 500 Da (500 Da is often referred to as the limit for proper skin penetration). 

The manufacturer claims that it can boost the synthesis of hyaluronic acid in the skin (up to 300% based on in-vitro tests) that is important for proper skin hydration and plumpness. It can also improve collagen fiber quality by increasing some structural skin elements (so-called proteoglycans), like decorin and lumican.

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The peptide is suggested for firming and remodelling treatments, as well as against skin sagging. It's also marketed as a "needle-free hyaluronan booster".

Tocopherol - goodie
Also-called: Vitamin E | What-it-does: antioxidant | Irritancy: 0-3 | Comedogenicity: 0-3
  • Primary fat-soluble antioxidant in our skin
  • Significant photoprotection against UVB rays
  • Vit C + Vit E work in synergy and provide great photoprotection
  • Has emollient properties
  • Easy to formulate, stable and relatively inexpensive
Read all the geeky details about Tocopherol here >>

It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It can be naturally found in fruits and teas but can also be made synthetically.

No matter the origin, in small amounts (up to 1%) it’s a nice, gentle preservative. Has to be combined with some other nice preservatives, like potassium sorbate to be broad spectrum enough.  

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In high amounts, it can be a skin irritant, but don’t worry, it’s never used in high amounts.

What-it-does: preservative

It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It’s not a strong one and doesn’t really work against bacteria, but more against mold and yeast. To do that it has to break down to its active form, sorbic acid. For that to happen, there has to be water in the product and the right pH value (pH 3-4). 

But even if everything is right, it’s not enough on its own. If you see potassium sorbate you should see some other preservative next to it too.

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BTW, it’s also a food preservative and even has an E number, E202.

What-it-does: preservative

A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi. 

It’s pH dependent and works best at acidic pH levels (3-5). It’s not strong enough to be used in itself so it’s always combined with something else, often with potassium sorbate.

Also-called: Form of Vitamin C | What-it-does: antioxidant | Irritancy: 0 | Comedogenicity: 2

A form of skincare superstar, vitamin C. Even though we are massive vitamin C fans,  Ascorbyl Palmitate  (AP) is our least favorite. (Btw, if you do not know what the big deal with vitamin C is then you are missing out. You must go and read our geeky details about it.) 

So, AP is one of the attempts by the cosmetics industry to solve the stability issues with vitamin C while preserving its benefits,  but it seems to fall short on several things.

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What's the problem?

Firstly, it's stability is only similar to that of pure ascorbic acid (AA), which means it is not really stable. A great study in the Journal of Cosmetic Dermatology compared a bunch of vitamin C derivatives and this derivative was the only one where the study said in terms of stability that it's "similar to AA". Not really that good.

Second, a study that examined the skin absorption of vitamin C found that ascorbyl palmitate did not increase the skin levels of AA. This does not mean that ascorbyl palmitate cannot penetrate the skin (because it can, it's oil soluble and the skin likes to absorb oil soluble things) but this means that it's questionable if ascorbyl palmitate can be converted into pure Vit C in the skin. Even if it can be converted, the palmitate part of the molecule is more than the half of it, so the efficacy will not be good and we have never seen a serum that contains a decent (and proudly disclosed) amount of AP.  We are highly skeptical what effect a tiny amount of AP has in a formula.

Third, another study that wanted to examine the antioxidant properties of AP was surprised to find that even though AP does have nice antioxidant properties; following UVB radiation (the same one that comes from the sun) it also promotes lipid peroxidation and cytotoxicity. It was only an in-vitro study meaning that it was done on cell cultures and not on real people, but still, this also does not support the use of AP too much. 

The only good thing we can write about Ascorbyl Palmitate is that there is an in-vitro (made in the lab, not on real people) study showing that it might be able to boost collagen production.

Regarding the skin-brightening properties of pure vitamin C, this is another magic property AP does not have, or at least there is no data, not even in-vitro, about it.

Overall, Ascorbyl Palmitate is our least favorite vitamin C derivative. It is there in lots of products in tiny amounts (honestly, we do not really understand why), however, we do not know about any vitamin C serum featuring AP in high amounts. That is probably no coincidence. If you are into vitamin C, you can take a look at more promising derivatives here

What-it-does: viscosity controlling

A kind of salt that's used as a thickener in cosmetic products. 

  • It's a super common and super debated skincare ingredient
  • It has several benefits: great solvent, penetration enhancer, creates cosmetically elegant, light formulas, great astringent and antimicrobial
  • It can be very drying if it's in the first few ingredients on an ingredient list
  • Some experts even think that regular exposure to alcohol damages skin barrier and causes inflammation though it's a debated opinion (read more in geeky details tab)
Read all the geeky details about Alcohol Denat. here >>

Ascorbic Acid - superstar
Also-called: Vitamin C, L-ascorbic acid | What-it-does: antioxidant, skin brightening
  • Works best between a concentration of 5-20%
  • Boosts the skin’s own collagen production
  • Fades pigmentation and brown spots
  • If used under sunscreen it boosts its UV protection
  • Extremely unstable and oxidizes very easily in presence of light or air
  • Stable in solutions with water only if pH is less than 3.5 or in waterless formulations
  • Vit E + C work in synergy and provide superb photoprotection
  • Ferulic acid doubles the photoprotection effect of Vit C+E and helps to stabilize Vit C
  • Potent Vit. C serums might cause a slight tingling on sensitive skin
Read all the geeky details about Ascorbic Acid here >>

Citric Acid - goodie
What-it-does: exfoliant, buffering

Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA. 

So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh. 

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There is also some research showing that citric acid with regular use (think three months and 20% concentration) can help sun-damaged skin, increase skin thickness and some nice hydrating things called glycosaminoglycans in the skin. 

But according to a comparative study done in 1995, citric acid has less skin improving magic properties than glycolic or lactic acid. Probably that’s why citric acid is usually not used as an exfoliant but more as a helper ingredient in small amounts to adjust the pH of a formulation. 

Also-called: Matrixyl synthe'6 | What-it-does: cell-communicating ingredient

It's a pretty new peptide trade-named MATRIXYL™ synthe’6. The manufacturer claims that it can boost the production of 6 major components of the skin matrix (collagen I, III, IV, fibronectin, hyaluronic acid and laminin 5) that result in more even skin and fewer wrinkles particularly on the forehead and crow's feet. Using 2% of the active for two months daily, women reported a decrease in wrinkles by 31% up to 100%.

Also-called: Yellow 6 | What-it-does: colorant

We don't have description for this ingredient yet.

Also-called: Tartrazine, Yellow 5 | What-it-does: colorant

Ci 19140  or Tartrazine is a super common colorant in skincare, makeup, medicine & food. It’s a synthetic lemon yellow that's used alone or mixed with other colors for special shades. 

FDA says it's possible, but rare, to have an allergic-type reaction to a color additive. As an example, it mentions that Ci 19140 may cause itching and hives in some people but the colorant is always labeled so that you can avoid it if you are sensitive. 

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0, 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
what‑it‑does emollient
A  low molecular weight dry, silky emollient ester that gives a light and non-greasy feel to the formulas. [more]
what‑it‑does solvent | moisturizer/humectant
A natural corn sugar derived glycol. It can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. [more]
what‑it‑does cell-communicating ingredient | skin brightening | anti-acne | moisturizer/humectant
A multi-functional skincare superstar that has clinically proven anti-aging, skin lightening, anti-inflammatory and barrier repair properties. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
what‑it‑does moisturizer/humectant
A sugar beet derived amino acid derivative with nice skin protection and moisturization properties. Its special thing is being an osmolyte, a molecule that helps to control cell-water balance.  [more]
what‑it‑does emollient
A very common emollient that makes your skin feel nice and smooth. Comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. [more]
what‑it‑does viscosity controlling
A white powdery thing that can mattify the skin and thicken up cosmetic products. [more]
what‑it‑does emollient
irritancy, com. 0, 1
A very common silicone that gives both skin and hair a silky smooth feel. It also forms a protective barrier on the skin and fills in fine lines. Also used for scar treatment. [more]
what‑it‑does emollient
irritancy, com. 2, 1
A synthetic liquid oil that can replace mineral oil or silicone oils in the cosmetic formulas. There are different grades depending on the molecular weight ranging from very light, volatile, non-residue leaving ones to more substantial, slight residue leaving ones.Apart from leaving the skin soft and smooth (emollient), it' [more]
what‑it‑does emollient | viscosity controlling
irritancy, com. 2, 2
A handy multi-tasker, white to light yellowish oil-loving wax that works very well in oil-in-water emulsions.  It makes your skin feel nice and smooth (emollient),  stabilizes oil-water mixes and gives body to them.Oh, and one more thing: [more]
what‑it‑does emollient
A clear, slightly yellow, odorless oil  that's a very common, medium-spreading emollient. It makes the skin feel nice and smooth and works in a wide range of formulas.
what‑it‑does emollient
A medium viscosity, odorless oily liquid that leaves an excellent afterfeel, with the skin feeling soft and conditioned. The feel is described by the manufacturer as slightly oily but not tacky or sticky. Dipentaerythrityl Hexacaprylate/Hexacaprate often comes to the formula mixed with two other emollients, Tridecyl Stearate, and  [more]
what‑it‑does emollient
A viscous, thick liquid emollient that gives lubricity and cushion at low use levels. [more]
what‑it‑does perfuming | solvent
A naturally occurring floral component with a delicate scent that can mask the odor of other raw materials. It also has remarkable antimicrobial and preservative boosting abilities.
what‑it‑does viscosity controlling
A kind of polymer (big molecule from repeated subunits) that helps to create beautiful gel-like textures. It's also a texturizer and thickener for oil-in-water emulsions. [more]
what‑it‑does viscosity controlling
A common helper ingredient that stabilizes emulsions and helps to thicken up products. [more]
what‑it‑does moisturizer/humectant | emollient
A handy multi-tasking ingredient that gives the skin a nice, soft feel and also boosts the effectiveness of other preservatives. [more]
what‑it‑does perfuming
The generic term for nice smelling stuff put into cosmetic products so that the end product also smells nice. It is made up of 30 to 50 chemicals on average. [more]
what‑it‑does emollient | viscosity controlling
irritancy, com. 1, 2
A super common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams. [more]
what‑it‑does surfactant/cleansing
what‑it‑does emollient | emulsifying
irritancy, com. 0, 1-2
Waxy, white, solid stuff that helps water and oil to mix together and leaves the skin feeling soft and smooth. [more]
what‑it‑does antioxidant | cell-communicating ingredient
A biomimetic peptide with antioxidant, anti-glycation and maybe collagen boosting abilities. It also protects against damages caused by infrared radiation. [more]
what‑it‑does emollient
A clear, colorless oily liquid that works as a medium feel emollient. It absorbs very quickly into the skin, leaves no shine and gives a nice, velvety after-feel.
what‑it‑does emollient
An emollient ester (basically an oil like liquid) with a light, elegant and silky feel. It gives a matte finish to the products. [more]
what‑it‑does emollient | emulsifying
The attachment of glycerin and oleic acid that works mainly as a co-emulsifier and stabilizer to create stable water-oil mixes, aka emulsions. It is also popular in cleansing products as it helps to thicken them up and has some refatting and skin-smoothing effect.  [more]
what‑it‑does solvent | moisturizer/humectant
A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent, and a broad spectrum antimicrobial. [more]
what‑it‑does skin-identical ingredient | antioxidant | moisturizer/humectant
A special, "cross-linked" from of hyaluronic acid (HA). Claimed to have five times the water-binding capacity of normal HA, also acts as an antioxidant and gives skin long-term moisture. [more]
what‑it‑does chelating
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. [more]
what‑it‑does moisturizer/humectant | solvent
A smallish polymer molecule that is used as a solubilizer and viscosity control agent in cosmetic products. [more]
what‑it‑does soothing
An exopolysaccharide secreted by a microorganism living in hydrothermal deep vents. It protects the skin against chemical, mechanical and UV aggressions. [more]
It's a "lifting" ingredient coming from plant raw materials. The manufacturer claims that it moisturizes, gives the skin softness and smoothness, and helps make-up to stay on after application. [more]
what‑it‑does cell-communicating ingredient
A small, three amino acid synthetic tripeptide that is claimed to increase structural elements in the skin like hyaluronic acid and proteoglycans. Might be effective against skin sagging. [more]
what‑it‑does antioxidant
irritancy, com. 0-3, 0-3
Pure Vitamin E. Great antioxidant that gives significant photoprotection against UVB rays. Works in synergy with Vitamin C. [more]
what‑it‑does preservative | perfuming | solvent | viscosity controlling
It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It can be naturally found in fruits and teas but can also be made synthetically. No matter the origin, in small amounts (up to 1%) it’s a nice, gentle preservative. [more]
what‑it‑does preservative
A not so strong preservative that doesn’t really work against bacteria, but more against mold and yeast. [more]
what‑it‑does preservative
A preservative that works mainly against fungi. Has to be combined with other preservatives. [more]
what‑it‑does antioxidant
irritancy, com. 0, 2
An oil soluble vitamin C derivative that has mixed data about its effectiveness. [more]
what‑it‑does viscosity controlling
A kind of salt that's used as a thickener in cosmetic products.
what‑it‑does antimicrobial/antibacterial | solvent | viscosity controlling
Alcohol with some additives to make it unconsumable. It is great solvent, penetration enhancer, creates cosmetically elegant, light formulas, great astringent, and antimicrobial. In large amounts, it can be very drying to the skin. [more]
what‑it‑does antioxidant | skin brightening
Pure Vitamin C. A skincare superstar that is clinically proven to boost collagen production (in 5-20% concentration), fade hyperpigmentation and boost UV protection under sunscreen. Also, it's extremely unstable and hard to formulate. [more]
what‑it‑does exfoliant | buffering
An AHA that comes from citrus fruits. It is usually used as a helper ingredient to adjust the pH of the formula. [more]
what‑it‑does cell-communicating ingredient
Matrixyl synthe'6 - A peptide that is claimed to be able to boost the production of 6 major components of the skin matrix (including collagen and hyaluronic acid). [more]
what‑it‑does colorant
what‑it‑does colorant
A super common colorant with the color yellow. [more]