Skincare Collagen And Vitamin C Eye Serum
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Azure Skincare Collagen And Vitamin C Eye SerumIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
- It's a helper ingredient that improves the freeze-thaw stability of products
- It's also a solvent, humectant and to some extent a penetration enhancer
- It has a bad reputation among natural cosmetics advocates but cosmetic scientists and toxicology experts do not agree (read more in the geeky details section)
A sugar beet-derived amino acid derivative with nice skin protection and moisturization properties. Betaine's special thing is being an osmolyte, a molecule that helps to control cell-water balance. It is also a natural osmoprotectant, meaning that it attracts water away from the protein surface and thus protects them from denaturation and increases their thermodynamic stability.
It also gives sensorial benefits to the formula and when used in cleansers, it helps to make them milder and gentler.
The chemically chopped up version of the big protein molecule, collagen. It is often derived from fish or bovine sources and works as a nice moisturizer and humectant that helps the skin to hold onto water.
To understand a bit more what Hydrolyzed Collagen is, you have to know that proteins are large chains of amino acids connected with so-called peptide bonds. These bonds can be broken up when a water molecule is added and the resulting thing is a mix of shorter length amino acids, also called peptides. So Hydrolyzed Collagen is not really collagen, it is rather an undefined and varying mix of largish peptides. Based on a manufacturer's data, the whole, soluble collagen has an average molecular weight of 300 000 Da, while this chopped up mixture has an average MW of 12 000 Da (still pretty big).
The main thing of these largish peptides is to act as water-binding agents, and to make the skin nice and smooth (aka emollient). Hydrolyzed Collagen is also often used in cleansers as it can make harsh surfactants milder and in hair conditioners as it improves the flexibility and manageability of hair.
If you wanna know more about collagen in cosmetics, we have a shiny explanation about soluble collagen here >>
- Works best between a concentration of 5-20%
- Boosts the skin’s own collagen production
- Fades pigmentation and brown spots
- If used under sunscreen it boosts its UV protection
- Extremely unstable and oxidizes very easily in presence of light or air
- Stable in solutions with water only if pH is less than 3.5 or in waterless formulations
- Vit E + C work in synergy and provide superb photoprotection
- Ferulic acid doubles the photoprotection effect of Vit C+E and helps to stabilize Vit C
- Potent Vit. C serums might cause a slight tingling on sensitive skin
Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.
BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.
It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive.
A very common ingredient that can be found in all cell membranes. In cosmetics it's quite the multi-tasker: it's an emollient and water-binding ingredient but it's also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes.
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula.
A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular.
- GHK-Cu is a copper-peptide complex found naturally in yucky bodily fluids (plasma, saliva, and urine)
- It has unique wound healing properties by stimulating the breakdown of unhealthy, too large collagen in scar tissue and stimulating nice and healthy collagen production afterwards
- It stimulates the production of several important skin-identical ingredients (e.g. collagen, elastin, and glycosaminoglycans)
- It has significant anti-inflammatory and antioxidant effect
- There are a few promising studies showing GHK-Cu can improve skin elasticity, clarity, firmness and reduce lines and wrinkles
- It can improve hair growth by enlarging hair follicles (and bigger follicles produce longer, thicker hair)
- There are some urban legends about possible overdosing or facial hair problems (read more in geeky details)
If you see a cosmetic product that claims that it has "Botox-like effect" then two things are almost certain: one, the product overpromises and two, it contains Argireline.
So this one is the famous peptide that's marketed by its manufacturer as the "Botox in a jar". The basis for this claim is that it targets the same wrinkle forming mechanism (wrinkles caused by facial muscle movement) as Botox, but the way it works is very different. In addition, the extent to which it can prevent muscles from contracting (and to smooth wrinkles) is very different (otherwise why would anyone use still Botox?).
The manufacturer did several studies to prove that Argireline really works and it does (just not as well as Botox). In-vivo (made on real people) tests showed that using 10% Argireline solution around the eyes for 15 days decreased wrinkles depth by 17%, while a 5% Argireline formula applied for 28 days did almost the same with a decrease in wrinkle depth by 16.26%. A Spanish University also did some research and found that Argireline increased the level of skin moisturization and decreased both the depth and width of wrinkles "significantly".
This means, Acetyl Hexapeptide-8 does have some ability to smooth wrinkles (but not as well as Botox - sorry, if we sound like a broken record). Also, we have to agree with TruthInAging, that it's not a collagen builder and not a preventer of structural aging (think vitamin C, AHAs or retinol); it's just a quick fix. If you are looking for one, this could be your thing. If you are more of a "let's treat this aging thing properly" type, then it's probably not your thing.
A pretty famous and better-researched peptide consisting of five amino acids (the building blocks of all proteins). It was created in a joint effort by the French ingredient supplier, Sederma and the cosmetics industry big shot, Procter&Gamble.
The amino acid sequence of the peptide is lysine–threonine–threonine–lysine–serine (KTTKS). Sometimes, it's also called collagen pentapeptide, as it's a subfragment of skin-structure-giving type I collagen. The KTTKS amino sequence is then attached for better oil solubility and skin penetration to palmitic acid and BOOM; we get Palmitoyl Pentapeptide-4.
Though most research is manufacturer sponsored, the clinical studies about Palmitoyl Pentapeptide-4 are promising. In short, it can reduce fine lines, wrinkles and improve skin texture significantly (and at crazy low concentrations, the studies were done with just 3 ppm that is 0.0003%).
There are also studies comparing Palmitoyl Pentapeptide-4 with anti-aging gold standard, retinol. One of them compared 3ppm Pal-KTTKS with 700 ppm (0.07%) retinol and found that they showed similar wrinkle improving ability with the peptide showing better skin tolerability.
Bottom line, if you are into peptides, this is a good one to try.
The sodium salt form of skincare superstar, vitamin C. If you do not know what the big fuss about vitamin C is, you are missing out and you have to click here and read all the geeky details about it.
Pure vitamin C (aka ascorbic acid, AA) is great and all, but its lack of stability is a big challenge for the cosmetics industry. One solution is to create stable derivatives that can be absorbed into the skin, convert there to AA and do all the magic AA is proven to do (which is being an antioxidant, a collagen booster, and a skin brightener).
SAP (the vit C derivative, not the enterprise software, obvs) is a promising derivative that has great stability up to pH 7. The challenge with it though is skin penetration. Unfortunately, it seems to be limited, or to quote a great article from the Journal of Cosmetic Dermatology "topically applied ascorbyl phosphate salts are, at very best, poorly absorbed in comparison with AA". Regarding conversion to AA, there seems to be no data about it, so we can neither deny nor confirm it.
We have better news regarding the three magic abilities of vitamin C: there is in-vivo (tested on real people) data showing that SAP does have photo-protective (aka antioxidant) properties, though less than pure AA. SAP might also aid collagen boosting; in-vitro (made in the lab) data shows that it works, but is less effective than another vitamin C derivative, called MAP (that seems to be as effective as pure AA). As for skin-brightening, there is a trade publication with in-vivo data showing that SAP can fade brown spots.
Another thing SAP might be able to do is to help with acne. A 2005 study showed in vitro (in test tubes) that 1% SAP has a strong antimicrobial activity on evil acne causing P. acnes and it also showed in vivo (on real people) that 5% SAP can strongly improve the inflammatory and non-inflammatory lesions of acne vulgaris. In fact, the results were comparable or even slightly better than with 5% benzoyl peroxide.
And there is even more regarding SAP and acne. A nice double-blind study from 2009 showed that 5% SAP reduced the inflammatory lesions by 20.14% and 48.82% within 4 and 8 weeks respectively and when combined with 0.2% retinol the results were even better. With this combination treatment, the improvement was 29.28% after 4 weeks and 63.10% after 8 weeks of application.
Aside from research studies, anecdotal evidence also supports SAP being a promising vitamin C derivative. One of the best-selling (vitamin C) serums in Sephora is the Ole Henriksen Truth Serum, while on Amazon it's the OzNaturals Vitamin C 20 Serum. Another popular choice is the Mad Hippie Vitamin C serum, and all of these contain vitamin C in the form of SAP.
Overall, we think SAP is a goody! In terms of anti-aging, it's probably not as effective as pure Ascorbic Acid, but it's totally worth a try. However, if your skin is acne-prone, SAP is your form of Vitamin C and it's a must-try.
Beta-Glucan is a nice big molecule composed of many smaller sugar molecules (called polysaccharide). It’s in the cell walls of yeast, some mushrooms, seaweeds, and cereals.
It’s a real goodie no matter if you eat it or put it on your face. Eating it is anti-diabetic, anti-cancer, and even lowers blood cholesterol.
Putting it on your face also does a bunch of good things: it‘s shown to have intensive skin repairing & wound healing properties, it’s a mild antioxidant, a great skin soother, and moisturizer, and it even shows promising anti-aging benefits.
The manufacturer of the ingredient did a published study with 27 people and examined the effect of 0.1% beta-glucan. They found that despite the large molecular size the smaller factions of beta-glucan penetrate into the skin, even into the dermis (the middle layer of the skin where wrinkles form). After 8 weeks there was a significant reduction of wrinkle depth and height and skin roughness has also improved greatly.
Bottom line: Beta-glucan is a great ingredient, especially for sensitive or damaged skin. It soothes, moisturizes, and has some anti-aging magic properties.
A derivative of Urea, that works as a strong moisturizer and humectant meaning that it helps the skin to cling onto water and thus to make it hydrated and elastic.
According to manufacturer's data, Hydroxyethyl Urea has a similar moisturizing ability to glycerin (measured at 5%), but it feels nicer on the skin as it is non-sticky and non-tacky and gives a lubricous and moist feeling to the skin.
The extract coming from the juice containing leaves of the Aloe vera plant. It's usually a hydroglycolic extract (though oil extract for the lipid parts also exists) that has similar moisturizing, emollient and anti-inflammatory properties as the juice itself. We have written some more about aloe here.
Portulaca Oleracea is a nice succulent with bright yellow flowers and edible nutritious vegetables. It's a famous plant in Korean traditional medicine to treat infection and irritated skin.
Modern research confirms that it's loaded with skin-goodies: it's the richest green plant source of omega-3 fatty acids (α-linolenic acid), contains NMFs (polysaccharides and amino acids), vitamins (β-carotene), minerals, and antioxidants (yellow betaxanthins and reddish betacyanins). Thanks to all its beneficial components, Purslane Extract has several magic properties: it's a great anti-inflammatory and antioxidant agent and also has wound healing abilities.
A castor oil derived, white, lard-like helper ingredient that is used as a solubilizer to put fragrances (those are oil loving things) into water-based products such as toners.
It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.
As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution".
In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).
What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists.
If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
Glyceryl acrylate/acrylic acid copolymer is the fancy word for a common polymer (big molecule from repeated subunits), namely polyacrylic acid (aka carbomer when it comes to cosmetics) with glycerin attached to it in some places.
The main thing of this polymer is that it forms a hydrogel (trade named Lubrajel) that can sit on top of the skin and provide moisturizing, water-soluble ingredients such as glycerin to the skin. Think of it as a very thin, wet sponge that a cosmetic manufacturer can fill with good ingredients for your skin. It also works as a thickening agent (remember, it is a carbomer type of molecule), and can provide the skin with a nice slippery feel. It can also draw water to the skin (thank you, pendant glycerol groups!), providing skin hydration.
Also, don’t let people scare you into thinking polyacrylic acid is dangerous because of the toxicity of acrylic acid. Since acrylic acid is dangerous due to its ability to absorb into the skin (since it’s small), when you chain them together into a polymer (which is big), this danger is no longer significant.
An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid).
Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier.
Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.
Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation.
If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.
As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily.
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.
Also, it's an effective deodorant and a medium spreading emollient.
A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
It is typically used in tiny amounts, around 0.1% or less.
Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!).
If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.
Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!).
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| what‑it‑does | solvent |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | moisturizer/humectant | solvent |
| irritancy, com. | 0, 0 |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | emollient | moisturizer/humectant |
| what‑it‑does | antioxidant | skin brightening | buffering |
| what‑it‑does | moisturizer/humectant | solvent |
| irritancy, com. | 0, 1 |
| what‑it‑does | emollient | emulsifying |
| what‑it‑does | emulsifying | surfactant/cleansing |
| irritancy, com. | 0, 0 |
| what‑it‑does | emollient |
| what‑it‑does | cell-communicating ingredient | soothing | antioxidant |
| what‑it‑does | cell-communicating ingredient | moisturizer/humectant |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | antioxidant | anti-acne |
| what‑it‑does | soothing | moisturizer/humectant |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | soothing | emollient | moisturizer/humectant |
| what‑it‑does | soothing | antioxidant |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | moisturizer/humectant | viscosity controlling |
| what‑it‑does | soothing | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | viscosity controlling |
| what‑it‑does | preservative |
| what‑it‑does | solvent |
| what‑it‑does | preservative |
| what‑it‑does | chelating |
| what‑it‑does | perfuming |