Wrinkle Repair GF Complex
Ingredients overview
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Key Ingredients
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Arcona Wrinkle Repair GF ComplexIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular.
A common multi-tasker fatty acid. It makes your skin feel nice and smooth (emollient), gives body to cream type products and helps to stabilize water and oil mixes (aka emulsions).
A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.
Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.
It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".
An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.
It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols. Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
A so-called fatty (the good, non-drying kind of) alcohol that does all kinds of things in a skincare product: it makes your skin feel smooth and nice (emollient), helps to thicken up products and also helps water and oil to blend (emulsifier). Can be derived from coconut or palm kernel oil.
The freeze-dried, powder form of coconut water (also called the liquid coconut endosperm) that's claimed to be loaded with all kinds of skin-nourishing things: proteins, amino acids, sugars, vitamins, minerals and growth hormones (kinetin) that support healthy cell growth and skin hydration.
According to the manufacturer's double blind placebo controlled clinical study, 8 weeks of using a 1% Cococin cream increased skin elasticity by 31.1%.
Sh-Oligopeptide-1 is the famous molecule, which is also called Epidermal Growth Factor or EGF. Chemically speaking, Growth Factors are largish peptides or smallish proteins, or to put it in another way, medium-length amino acid sequences (EGF consists of 53 amino acids). Biologically speaking, Growth Factors are cellular signal molecules that can stimulate cell growth, proliferation, healing and/or differentiation.
There are lots of Growth Factors and EGF is just one of them. The topic of "Growth Factors and skincare" is a big, confusing and controversial one and we will try our best to summarize the story for you, including the pros and the cons.
EGF is a special snowflake when it comes to skincare as it was the first Growth Factor that made its way into cosmetic products and it is also the most common one. The American biochemist, Stanley Cohen discovered EGF and was awarded a Noble prize in 1986 for it. As the Noble prize may signify, the molecule is significant and powerful and directly stimulates the proliferation of epidermal cells.
When it comes to Sh-Oligopeptide-1 in a cosmetic product, it has pretty well-established wound healing and skin renewal properties. It might even do more than that. According to a 2012 study on a serum containing barley bioengineered epidermal growth factor, "clinical evaluations showed statistically significant improvement in the appearance of fine lines and rhytids, skin texture, pore size, and various dyschromatic conditions apparent within the first month of use, and continuing improvement trends for the duration of the study" (which was 3 months).
This all sounds amazing, "give me some EGF Serum", we can hear you say! But as we wrote in the intro, the topic is complex and controversial so here are some of the questions that keep coming up around slathering EGF all over our face.
The first and biggest concern is that if EGF is so good at stimulating cell proliferation, how does it relate to cancer? Is the definition of cancer not "cells proliferating out of control"? Most experts agree on this answer: EGF is mitogenic (= stimulates cell proliferation) but not mutagenic (= does not alter the cell to make it cancerous). If you do not have cancer, you will not get cancer from EGF. However, if you have cancerous cells, EGF will help them to spread, just like it helps healthy cells. So if you have a lot of moles, excessive UV exposure in the past, or if you have any of the skin cancer risk factors, we suggest you should think twice about using EGF products. The same is true if you have psoriasis, a skin disease related to the abnormal growth of epidermal skin cells. You do not want to add fuel to the fire with EGF.
Other (less serious) concerns are if EGF can properly penetrate the skin (as it is a medium-sized, polar molecule, so a special delivery system is probably needed), if it can affect collagen synthesis (or just works on the surface plumping up only the upmost layers of the skin) and if it has beneficial effects at all when used in isolation versus when used in a "conditioned media" that contains lots of growth factors resembling the synergistic balance found in the skin.
Overall, our impression is that EGF is definitely a potent molecule. Some EGF products have a cult-like following adding anecdotal evidence to the clinical studies showing EGF has a beneficial effect on the skin. If you like experimenting, by all means, go ahead (unless you have psoriasis or high skin cancer risk factors), but if you are a better safe than sorry type, stick to daily SPF + a good retinoid product. This duo is still the golden standard of anti-aging.
Are you interested in Growth Factors and skincare? We have some more here:
- Human Fibroblast Conditioned Media - a growth factor cocktail used in some cosmetic products
- Insulin-like growth factor 1, aka sh-Oligopeptide -2 - a pal of EGF composed of 70 amino acids
- Vascular Endothelial Growth Factor, aka Sh-Polypeptide-9 - part of a GF cocktail trade named BIO-Placenta
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
Super common soothing ingredient. It can be found naturally in the roots & leaves of the comfrey plant, but more often than not what's in the cosmetic products is produced synthetically.
It's not only soothing but it' also skin-softening and protecting and can promote wound healing.
It's an ester form of vitamin A (retinol + palmitic acid) that belongs to the "retinoid family". The retinoid family is pretty much the royal family of skincare, with the king being the FDA-approved anti-aging ingredient tretinoin. Retinol is also a very famous member of the family, but it's like Prince George, two steps away from the throne. Retinyl palmitate will be then Prince Charlotte (George's little sister), quite far (3 steps) away from the throne.
By steps, we mean metabolic steps. Tretinoin, aka retinoic acid, is the active ingredient our skin cells can understand and retinyl palmitate (RP) has to be converted by our metabolic machinery to actually do something. The conversion is a 3 step one and looks like this:
retinyl palmitate --> retinol -- > retinaldehyde --> all-trans-retinoic acid
As we wrote in our lengthy retinol description the problem is that the conversion is not terribly effective. The evidence that RP is still an effective anti-aging ingredient is not very strong, in fact, it's weak. Dr. Leslie Baumann in her fantastic Cosmetic Dermatology book writes that RP is topically ineffective.
What's more, the anti-aging effectiveness is not the only questionable thing about RP. It also exibits questionable behaviour in the presence of UV light and was the center of a debate between the non-profit group, EWG (whose intentions are no doubt good, but its credibility is often questioned by scientists) and a group of scientists and dermatologists lead by Steven Q. Wang, MD, director of dermatologic surgery at Memorial-Sloan Kettering Cancer Centre.
Dr. Leslie Baumann wrote a great review of the debate and summarized the research available about retinyl palmitate here. It seems that there is a study showing RP being photo protective against UVB rays but there is also a study showing RP causing DNA damage and cytotoxicity in association with UVA.
We think that the truth lies somewhere in the middle, and we agree with Dr. Baumann's conclusion: "sufficient evidence to establish a causal link between RP and skin cancer has not been produced. Nor, I’m afraid, are there any good reasons to recommend the use of RP". We would add especially during the day!
Bottom line: If you wanna get serious about retinoids, RP is not your ingredient (retinol or tretinoin is!). However, if you use a product that you like and it also contains RP, there is no reason to throw it away. If possible use it at night, just to be on the safe side.
- Primary fat-soluble antioxidant in our skin
- Significant photoprotection against UVB rays
- Vit C + Vit E work in synergy and provide great photoprotection
- Has emollient properties
- Easy to formulate, stable and relatively inexpensive
A spray-dried or freeze-dried version of Aloe Leaf Juice. The point of both drying methods is to make water evaporate from the juice and leave just the "useful" components behind.
So the aloe powder has similar soothing, emollient and moisturizing properties as the juice. You can read a bit more about the juice here.
You probably know olive oil from the kitchen as a great and healthy option for salad dressing but it's also a great and healthy option to moisturize and nourish the skin, especially if it's on the dry side.
Similar to other emollient plant oils, it's loaded with nourishing fatty acids: oleic is the main component (55-83%), and also contains linoleic (3.5-20%) and palmitic acids (7-20%). It also contains antioxidant polyphenols, tocopherols (types of vitamin E) and carotenoids and it's one of the best plant sources of skin-identical emollient, Squalene.
Overall, a great option for dry skin but less so for acne-prone or damaged skin.
Sweet, exotic and floral, it’ no surprise that Ylang Ylang is a popular essential oil. It is coming from the yellow, fragrant flowers of the Cananga tree native to tropical Asia and, similar to other essential oils, it is a chemically complex mixture with several pros and cons.
Unfortunately, these are a bit tricky to pin down as the composition varies largely depending on where it is sourced, how the oil is extracted and the grade of it that is used in the product, but we’ll do our best!
Let’s start with the easy stuff. The main components are fragrant molecules, including super common linalool (1-19%), benzyl benzoate (2-10%) and several others adding up to a max amount of 37.6% of EU sensitizers. The most expensive Extra grade is the most fragrant (has more benzyl acetate and cresyl methyl ether) and is used in high-end perfumes, while the First and Second grades are less fragrant, and used mainly in cosmetics.
Other than smelling nice and making cosmetic formulas also smell nice, Ylang Ylang might have some antimicrobial and antioxidant benefits and also works as an insect repellent. Its nice smell is also commonly known as being relaxing and calming (also backed up by a few recent studies), but it is an aromatherapy use case (when inhaled) so this probably does not count much skincare-wise.
On the other hand, the nice smell also means allergen fragrant components and 37.6% of EU sensitizers counts as quite high and the oil is considered to have high skin sensitization potential. It is a good idea to avoid if your skin is sensitive.
We don't have description for this ingredient yet.
We have to start by writing how fascinated we are by the amazing lavender fields of Provance and we do love pretty much everything about lavender: its look, its color, its scent.... but, when it comes to skincare, lavender is a questionable ingredient that you probably do not want in your skincare products.
First, let us start with the pros: it has a lovely scent, so no wonder that it is popular as a fragrance ingredient in natural products wanting to be free from synthetic fragrances but still wanting to smell nice. The scent of lavender is famous for having calming and relaxing properties and some smallish scientific studies do support that. Inhaled volatile compounds seem to have a soothing effect on the central nervous system and studies have shown that lavender aromatherapy can improve patient's anxiety and experience in hospitals.
Another pro is that lavender oil has some nice antimicrobial and antibacterial properties. It also has some local pain relieving and muscle relaxing magical powers. Lavender oil is also often claimed to have anti-inflammatory properties. We have found a study confirming this but it was the essential oil of the leaves and not the much more commonly used flowers and the two differ in their main chemical compounds very much. (The main components of the flower essential oil are linalyl acetate and linalool [around 80% the two together] while it is 1,8-Cineole [around 65%] in the essential oil of the leaves.)
Now, let us look at the cons: similar to a bunch of other essential oils, the main components of lavender oil are potentially irritating fragrant components. The two main components are linalyl acetate (about 50%) and linalool (about 35%) and both autoxidise on exposure to the air forming strong contact allergens. To make things even worse, lavender oil seems to be cytotoxic from concentrations as low as 0.25% (concentration up to 0.125% were ok).
There is also an often cited Japanese study that made patch tests with lavender oil for 9 years and found a huge increase in lavender oil sensitivity in 1997 (from 1.1% in 1990 to 8.7% in 1997 and 13.9% in 1998). This was the year when using dried lavender flowers in pillows, wardrobes, and elsewhere became fashionable in Japan, so it seems that increased exposure to lavender results in increased risk of sensitivity.
Overall, it makes us sad to write bad things about such a lovely plant, but when it comes to skincare, you will be better off without lavender.
We don't have description for this ingredient yet.
The essential oil coming from the rind of the orange (the sweet one). In general, the main component of citrus peel oils is limonene (83-97% for sweet orange peel), a super common fragrant ingredient that makes everything smell nice (but counts as a frequent skin sensitizer).
Other than that, citrus peel also contains the problematic compound called furanocoumarin that makes them mildly phototoxic. Orange peel contains less of it than some other citruses (like bergamot or lime), but still, be careful with it especially if it is in a product for daytime use.
The emollient plant oil that comes from almonds. Similar to other plant oils, it is loaded with skin-nourishing fatty acids (oleic acid - 55-86% and linoleic acid 7-35%) and contains several other skin goodies such as antioxidant vitamin E and vitamin B versions.
It's a nice, basic oil that is often used due to its great smoothing, softening and moisturizing properties. It's also particularly good at treating dry brittle nails (source).
We don't have description for this ingredient yet.
Lonicera Japonica, or Japanese Honeysuckle as normal people call it, is a white-flowered honeysuckle known for being a traditional Chinese medicine. Modern research confirms that the plant has a super complex chemical composition with more than 140 compounds identified with possible anti-inflammatory, antibacterial, antiviral, antioxidative and hepatoprotective activities.
As for Lonicera Japonica Flower Extract in skin care, it can have two main roles. The first one is being an anti-inflammatory and soothing ingredient, probably due to chlorogenic acid, a polyphenol thought to be the main bioactive component of the flower.
The other possible role is being a natural preservative. If this is the case, it is coupled with its Italian Honeysuckle cousin to form a broad spectrum antimicrobial preservative blend. You can read about this more here.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA.
So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh.
There is also some research showing that citric acid with regular use (think three months and 20% concentration) can help sun-damaged skin, increase skin thickness and some nice hydrating things called glycosaminoglycans in the skin.
But according to a comparative study done in 1995, citric acid has less skin improving magic properties than glycolic or lactic acid. Probably that’s why citric acid is usually not used as an exfoliant but more as a helper ingredient in small amounts to adjust the pH of a formulation.
Though its name says acid, it's not really an exfoliant. It's a plant extract with some antioxidant properties. Its main thing in cosmetic products is to neutralize the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. It's a natural alternative to sometimes bad-mouthed chelating agents, EDTAs.
It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It’s not a strong one and doesn’t really work against bacteria, but more against mold and yeast. To do that it has to break down to its active form, sorbic acid. For that to happen, there has to be water in the product and the right pH value (pH 3-4).
But even if everything is right, it’s not enough on its own. If you see potassium sorbate you should see some other preservative next to it too.
BTW, it’s also a food preservative and even has an E number, E202.
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| what‑it‑does | solvent |
| what‑it‑does | emollient |
| what‑it‑does | emollient | viscosity controlling |
| irritancy, com. | 0, 2-3 |
| what‑it‑does | emollient | emulsifying |
| irritancy, com. | 0, 1 |
| what‑it‑does | emollient | viscosity controlling | emulsifying | surfactant/cleansing |
| irritancy, com. | 1, 2 |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | emollient | viscosity controlling |
| irritancy, com. | 2, 2 |
| what‑it‑does | emollient | moisturizer/humectant |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | soothing |
| irritancy, com. | 0, 0 |
| what‑it‑does | cell-communicating ingredient |
| irritancy, com. | 1-3, 1-3 |
| what‑it‑does | antioxidant |
| irritancy, com. | 0-3, 0-3 |
| what‑it‑does | soothing | moisturizer/humectant |
| what‑it‑does | antioxidant | emollient |
| irritancy, com. | 0, 0-2 |
| what‑it‑does | perfuming |
| what‑it‑does | perfuming |
| what‑it‑does | antimicrobial/antibacterial | perfuming |
| what‑it‑does | perfuming |
| what‑it‑does | perfuming |
| what‑it‑does | emollient |
| irritancy, com. | 0, 1-3 |
| what‑it‑does | perfuming |
| what‑it‑does | soothing | antimicrobial/antibacterial |
| what‑it‑does | emulsifying | perfuming |
| irritancy, com. | 0, 0-3 |
| what‑it‑does | emollient |
| what‑it‑does | buffering |
| what‑it‑does | chelating |
| what‑it‑does | preservative |