Clinical Discoloration Repair Serum
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Paula's Choice Clinical Discoloration Repair SerumIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
- A multi-functional skincare superstar with several proven benefits for the skin
- Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
- Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
- Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
- Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
We don't have description for this ingredient yet.
A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular.
A clear, colorless, almost odorless oil that spreads nicely and easily and gives a velvet dry skin feel. It is good friends with sunscreen agents and helps to solubilize them. Also, it makes sunscreens feel lighter and spread easier.
We don't have description for this ingredient yet.
A biodegradable emollient that gives a fresh gliding sensation and a powdery after feel. It works well with all kinds of oils including natural and silicone oils.
A fatty alcohol (the non-drying type with a long oil loving chain of 22 carbon atoms) that is used to increase the viscosity of the formula and it also helps the oily and the watery parts to stay nicely mixed together (called emulsion stabilizing).
A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.
Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.
It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".
Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.
BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.
It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive.
The emollient plant oil coming from Milk Thistle, the yearling plant with purple flowers. Similar to many other plant oils, its main fatty acids are barrier-repairing linoleic (53%) and skin-nourishing oleic (21%) and also contains some antioxidant vitamin E (600 mg/kg).
It is claimed to be a cosmetically elegant oil that spreads easily and absorbs quickly into the skin. The manufacturer also recommends the oil for skin types suffering from chronic inflammatory disorders such as psoriasis or acne.
- Primary fat-soluble antioxidant in our skin
- Significant photoprotection against UVB rays
- Vit C + Vit E work in synergy and provide great photoprotection
- Has emollient properties
- Easy to formulate, stable and relatively inexpensive
We don't have description for this ingredient yet.
A very common ingredient that can be found in all cell membranes. In cosmetics it's quite the multi-tasker: it's an emollient and water-binding ingredient but it's also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes.
At first glance, you could think that Bakuchiol is your average plant extract. It is derived from the seeds of Psoralea Corylifolia, aka Babchi, a plant important in Indian and Chinese medicine. The molecule was first isolated in 1973 and several anti-something properties are known about it: it has anti-inflammatory, antioxidant, anti-tumor, anti-bacterial and hepatoprotective magical abilities like plenty of other Ayurvedic plant extracts.
What makes Bakuchiol a special snowflake is the recent discovery that it behaves on the skin in a way very similar to well-known skincare superstar, retinol. While chemically, it has nothing to do with the vitamin-A family, aka retinoids, comparative gene expression profiling (a fancy way of saying that they compared how retinol and bakuchiol modify the way skin cells behave and produce important skin proteins such as collagen) shows that retinol and bakuchiol regulate skin cell behavior in a similar way.
To be more specific, both Bakuchiol and retinol upregulate collagen I, III and IV production and downregulate MMP, the evil collagen attacking enzyme in our skin. This means more collagen stays in our skin and we all know that more collagen equals firmer, more wrinkle-free skin. A 12-week clinical study using a 0.5% Bakuchiol formula with 17 people using it twice a day confirmed a significant improvement in lines and wrinkles, elasticity, firmness and an overall reduction in photo-damage. Also, the test formula was very well tolerated, without any retinol-like side effects.
What's more, a 2018 double-blind study with 44 people compared 0.5% Bakuchiol with 0.5% retinol cream and found that "bakuchiol is comparable to retinol in its ability to improve photoaging and is better tolerated than retinol". A super promising result after 12 weeks.
If you are not a daredevil-type who doesn't want to stop using a super well-proven retinol for a newbie like Bakuchiol, we have good news. The two also work very nicely together and Bakuchiol can actually help to stabilize the otherwise unstable and hard to formulate retinol.
And we are still not done, as Bakuchiol shows not only anti-aging properties but also nice anti-acne effects. 1% Bakuchiol seems to be very effective in itself (57% reduction in acne after 6 weeks treatment) and even better when combined with 2% salicylic acid (67% reduction in acne after 6 weeks). We like that Bakuchiol is such a good team player! The molecule works against acne in multiple ways: It downregulates 5α-reductase (a sebum-controlling enzyme), it is antibacterial (including P. acnes), anti-inflammatory and it inhibits lipid-peroxidation, an evil oxidative process that is recently thought to be a very early trigger in the acne process.
We feel that this description is becoming very long so we will just mention that Bakuchiol also seems to positively regulate hydration-related genes such as Aquaporin 3 and also shows some melanin-inhibiting properties.
Overall, we think Bakuchiol is an awesome molecule with lots of promise both for anti-aging and anti-acne. But the proof compared to the well-established superstars is far from solid, so in a skincare routine, we would rather add Bakuchiol next to retinol than straight up replace it. Unless you are a gimme-the-newest-shiny-thing-under-the-sun-type.
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol.
The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.
It's the chemically chopped up version of normal lecithin. Most often it's used to create liposomes and to coat and stabilize other ingredients.
Super common soothing ingredient. It can be found naturally in the roots & leaves of the comfrey plant, but more often than not what's in the cosmetic products is produced synthetically.
It's not only soothing but it' also skin-softening and protecting and can promote wound healing.
The emollient plant oil coming from the soybean. It is considered to be a nice, cost-effective base oil with moisturizing properties. As for its fatty acid profile, it contains 48-59% barrier-repairing linoleic acid, 17-30% nourishing oleic acid and also some (4.5-11%) potentially anti-inflammatory linolenic acid.
Similar to other glycols, it's a helper ingredient used as a solvent, or to thin out thick formulas and make them more nicely spreadable.
Hexylene Glycol is also part a preservative blend named Lexgard® HPO, where it helps the effectiveness of current IT-preservative, phenoxyethanol.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA.
So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh.
There is also some research showing that citric acid with regular use (think three months and 20% concentration) can help sun-damaged skin, increase skin thickness and some nice hydrating things called glycosaminoglycans in the skin.
But according to a comparative study done in 1995, citric acid has less skin improving magic properties than glycolic or lactic acid. Probably that’s why citric acid is usually not used as an exfoliant but more as a helper ingredient in small amounts to adjust the pH of a formulation.
It’s one of those little helper ingredients that makes sure the product stays the same over time. No color change or anything like that. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
Malic acid comes from apple and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA.
So malic acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh.
There is not much research out there about malic acid itself. We could find one comparative study, that compared the effectiveness of glycolic acid, lactic acid, citric acid and malic acid. The first two ones were the winners while malic and citric acid were less effective.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.
Also, it's an effective deodorant and a medium spreading emollient.
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| what‑it‑does | solvent |
| what‑it‑does | cell-communicating ingredient | skin brightening | anti-acne | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | skin brightening | soothing |
| what‑it‑does | emollient |
| what‑it‑does | emollient |
| what‑it‑does | solvent | emollient |
| what‑it‑does | emollient | viscosity controlling |
| what‑it‑does | emollient | emulsifying |
| irritancy, com. | 0, 1 |
| what‑it‑does | moisturizer/humectant | solvent |
| irritancy, com. | 0, 1 |
| what‑it‑does | emollient |
| what‑it‑does | antioxidant |
| irritancy, com. | 0-3, 0-3 |
| what‑it‑does | emollient | emulsifying |
| what‑it‑does | cell-communicating ingredient | antioxidant | antimicrobial/antibacterial |
| what‑it‑does | viscosity controlling |
| what‑it‑does | moisturizer/humectant | emollient |
| what‑it‑does | emollient | emulsifying |
| what‑it‑does | soothing |
| irritancy, com. | 0, 0 |
| what‑it‑does | emollient | perfuming |
| irritancy, com. | 0, 3 |
| what‑it‑does | solvent | emulsifying | perfuming | surfactant/cleansing |
| irritancy, com. | 0-1, 0-2 |
| what‑it‑does | emollient |
| what‑it‑does | buffering |
| what‑it‑does | chelating |
| what‑it‑does | exfoliant | buffering |
| what‑it‑does | preservative |
| what‑it‑does | preservative |