Follow us on our new Insta page »
Dr. Diamond's Metacine Instafacial Plasma

Instafacial Plasma

Formulated with bioengineered human identical growth factors that simulate platelet-rich plasma’s ability to support skin repair & rejuvenation. Fortified with polypeptides & sodium hyaluronate, this weightless serum should be used morning & night. Leaves skin looking more lifted, firmer, tighter & luminous. When used in tandem with emulsion night cream, achieve clinically proven results.
Uploaded by: giovannac on

Skim through

Ingredient name what-it-does irr., com. ID-Rating
Water solvent
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
1,2-Hexanediol solvent
Nicotiana Benthamiana Hexapeptide-40 SH-Oligopeptide-1
N-Prolyl Palmitoyl Tripeptide-56 Acetate
SH-Oligopeptide-1 cell-communicating ingredient
SH-Oligopeptide-2 cell-communicating ingredient
SH-Polypeptide-1 cell-communicating ingredient
SH-Polypeptide-11 cell-communicating ingredient
SH-Polypeptide-9 cell-communicating ingredient
Acetyl Hexapeptide-8 cell-communicating ingredient, moisturizer/​humectant goodie
Acetyl Glutamine
Copper Tripeptide-1 cell-communicating ingredient, soothing, antioxidant goodie
Raphanus Sativus (Radish) Root Extract
Bacillus/Folic Acid Ferment Filtrate Extract antioxidant, moisturizer/​humectant
4-Hydroxyacetophenone antioxidant
Disodium Acetyl Glucosamine Phosphate moisturizer/​humectant goodie
Sodium Glucuronate moisturizer/​humectant
Sodium Hyaluronate skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Sodium Phytate chelating
Magnesium Sulfate viscosity controlling
Hydroxyethyl Cellulose viscosity controlling
Lecithin emollient, emulsifying goodie
Citric Acid buffering
Maltodextrin
Bio Propanediol solvent, moisturizer/​humectant
Butylene Glycol moisturizer/​humectant, solvent 0, 1
Bio-Pentylene Glycol solvent, moisturizer/​humectant
Ethylhexylglycerin preservative
Caprylyl Glycol moisturizer/​humectant, emollient
2-Phenoxyethanol preservative

Dr. Diamond's Metacine Instafacial Plasma
Ingredients explained

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

What-it-does: solvent

A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Also-called: Epidermal Growth Factor, EGF, rh-Oligopeptide-1 | What-it-does: cell-communicating ingredient

Sh-Oligopeptide-1 is the famous molecule, which is also called Epidermal Growth Factor or EGF. Chemically speaking, Growth Factors are largish peptides or smallish proteins, or to put it in another way, medium-length amino acid sequences (EGF consists of 53 amino acids).  Biologically speaking, Growth Factors are cellular signal molecules that can stimulate cell growth, proliferation, healing and/or differentiation. 

There are lots of Growth Factors and EGF is just one of them. The topic of "Growth Factors and skincare" is a big, confusing and controversial one and we will try our best to summarize the story for you, including the pros and the cons. 

Also-called: Insulin-like growth factor 1, IGF-1, rh-Oligopeptide-2 | What-it-does: cell-communicating ingredient

Sh-Oligopeptide-2 is also called Insulin-like growth factor 1 and it belongs to the same group of ingredients (Growth Factors) as its better-known sister, Epidermal Growth Factor or Sh-Oligopeptide-1. This guy consists of 70 amino acids and, similar to EGF, it is also claimed to stimulate cell proliferation and wound healing. There is also a study that indicates EGF and IGF1 work in synergy to promote keratinocyte (skin cell) proliferation. 

The topic of Growth Factors in skincare is complex and controversial. If you are new to it, read our shiny explanation on EGF to get a (hopefully) balanced impression about the pros and cons.

Also-called: Basic Fibroblast Growth Factor, FGF2, rh-Polypeptide-1 | What-it-does: cell-communicating ingredient

Sh-Polypeptide-1 is a cell signaling protein also called Basic Fibroblast Growth Factor and is twin sister to Acidic Fibroblast Growth Factor. We can write here pretty much the same things as we did on aFGF: it is a mitogenic (= stimulates cell proliferation) ingredient that stimulates fibroblast cell growth and proliferation. According to manufacturer info, it also stimulates the synthesis of collagen and other extracellular-matrix (the gooey stuff between cells) components. 

Growth Factors and skincare is a big, complicated and controversial topic, so if you wanna know more, we have a more detailed explanation on Epidermal Growth Factor, the most common one used in skincare.

Also-called: Acidic Fibroblast growth factor, FGF1, rh-Polypeptide-11 | What-it-does: cell-communicating ingredient

Sh-Polypeptide-11 is a medium sized cell signaling molecule also called Acidic Fibroblast Growth Factor. It belongs to the same group of ingredients (Growth Factors) as its better-known sister, Epidermal Growth Factor or Sh-Oligopeptide-1. As its name suggests, FGF can stimulate the growth and proliferation of fibroblast cells (VIP cells that produce among other things collagen). According to manufacturer info, it also stimulates skin regeneration, wound healing and collagen and elastin synthesis. 

As for research, we could find an in-vitro study that proved that "Recombinant FGF-1 strongly stimulated fibroblast and keratinocyte proliferation. However, the transition of this protein through the SC required an appropriate carrier system - lipid spheres." 

Also-called: Vascular Endothelial Growth Factor, VEGF, rh-Polypeptide-9, part of BIO-Placenta | What-it-does: cell-communicating ingredient

Sh-Polypeptide-9 is a cell signaling protein also called Vascular Endothelial Growth Factor. As its name suggests, its main function is to stimulate the formation of blood vessels. As to what it does in cosmetic products, we found manufacturers info claiming that it plays a role in supplying fibroblast cells (VIP skin cells that make collagen) with nutrients, in the growth and migration of cells and in wound healing

It usually comes to the formula as part of a Growth Factor mix trade named BIO-Placenta, that combines EGF, IGF-1, FGF1, FGF2 and this guy to form a synergistic growth factor cocktail. BIO Placenta is claimed to do pretty much everything you would want from an anti-aging active including anti-wrinkle, skin rejuvenation, elasticity enhancement, moisturizing and cell vitalization properties. 

Also-called: Argireline, Acetyl Hexapeptide-3 | What-it-does: cell-communicating ingredient, moisturizer/humectant

If you see a cosmetic product that claims that it has "Botox-like effect" then two things are almost certain: one, the product overpromises and two, it contains Argireline. 

So this one is the famous peptide that's marketed by its manufacturer as the "Botox in a jar". The basis for this claim is that it targets the same wrinkle forming mechanism (wrinkles caused by facial muscle movement) as Botox, but the way it works is very different. In addition, the extent to which it can prevent muscles from contracting (and to smooth wrinkles) is very different (otherwise why would anyone use still Botox?). 

We don't have description for this ingredient yet.

Also-called: GHK-Cu, Copper Peptide | What-it-does: cell-communicating ingredient, soothing, antioxidant
  • GHK-Cu is a copper-peptide complex found naturally in yucky bodily fluids (plasma, saliva, and urine)
  • It has unique wound healing properties by stimulating the breakdown of unhealthy, too large collagen in scar tissue and stimulating nice and healthy collagen production afterwards
  • It stimulates the production of several important skin-identical ingredients (e.g. collagen, elastin, and glycosaminoglycans)
  • It has significant anti-inflammatory and antioxidant effect
  • There are a few promising studies showing GHK-Cu can improve skin elasticity, clarity, firmness and reduce lines and wrinkles
  • It can improve hair growth by enlarging hair follicles (and bigger follicles produce longer, thicker hair)
  • There are some urban legends about possible overdosing or facial hair problems (read more in geeky details)
Read all the geeky details about Copper Tripeptide-1 here >>

What-it-does: astringent

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

What-it-does: antioxidant

A handy multifunctional ingredient that works as a preservative booster, as well as an antioxidant and soothing agent

Also-called: NovHyal | What-it-does: moisturizer/humectant

It's a "bioengineered" from of skin building block N-acetylglucosamine-6-phosphate (NAG6P) that is used by the skin to  synthesize important skin-identical humectants like GAGs and hyaluronan.  

According to the manufacturer's in-vitro and ex-vivo (made in the lab not on real people) tests, NovHyal can boost GAGs production both in the upper and middle layer of the skin by 84% in 10 days. It can also increase hyaluronic acid synthesis by 282% in just 2 days. Sounds good, though some in-vivo tests (made on real people) would be nice.

What-it-does: moisturizer/humectant

We don't have description for this ingredient yet.

What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It’s the - sodium form - cousin of the famous NMFhyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

What-it-does: chelating

It’s one of those little helper ingredients that makes sure the product stays the same over time. No color change or anything like that. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. 

Also-called: Epsom salt | What-it-does: viscosity controlling

A helper ingredient that is used as a bulking and viscosity controlling agent. It is also an emulsion stabilizer in water-in-oil emulsions, where water droplets are dispersed in the continuous oil phase and not the other way round.

It can also be used as a heat generating agent in water-less formulas as it has an instant heat-generating chemical reaction with water. 

Also-called: HEC;Hydroxyethylcellulose | What-it-does: viscosity controlling, emulsion stabilising

A nice little helper ingredient that can thicken up cosmetic products and create beautiful gel formulas. It's derived from cellulose, the major component of the cell wall of green plants. It is compatible with most co-ingredients and gives a very good slip to the formulas. 

Lecithin - goodie
What-it-does: emollient, emulsifying

A very common ingredient that can be found in all cell membranes. In cosmetics it's quite the multi-tasker: it's an emollient and water-binding ingredient but it's also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes

What-it-does: buffering

Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA. 

So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh. 

It's a little helper ingredient coming from corn, rice or potato starch that can help to keep skin mat (absorbent), to stabilise emulsions, and to keep the product together (binding). 

Also-called: Zemea;Propanediol | What-it-does: solvent, moisturizer/humectant

Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved. 

It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. 

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent and a broad spectrum antimicrobial. According to manufacturer info, it's also a moisturizer and helps to make the product feel great on the skin. It works synergistically with preservatives and helps to improve water-resistance of sunscreens. 

What-it-does: preservative, deodorant

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient

It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol

The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
what‑it‑does solvent
A multi-functional helper ingredient that acts as a humectant and emollient. It's also a solvent and can boost the effectiveness of preservatives. [more]
what‑it‑does cell-communicating ingredient
Epidermal Growth Factor - a smallish protein that works as a potent cell signaling molecule. It stimulates cell proliferation, wound healing and skin renewal. Do not use if you have psoriasis or high skin cancer risk factors. [more]
what‑it‑does cell-communicating ingredient
Sh-Oligopeptide-2 is also called Insulin-like growth factor 1 and it belongs to the same group of ingredients (Growth Factors) as its better-known sister, Epidermal Growth Factor or Sh-Oligopeptide-1. [more]
what‑it‑does cell-communicating ingredient
Sh-Polypeptide-1 is a cell signaling protein also called Basic Fibroblast Growth Factor and is twin sister to Acidic Fibroblast Growth Factor. [more]
what‑it‑does cell-communicating ingredient
Sh-Polypeptide-11 is a medium sized cell signaling molecule also called Acidic Fibroblast Growth Factor. It belongs to the same group of ingredients (Growth Factors) as its better-known sister, Epidermal Growth Factor or Sh-Oligopeptide-1. [more]
what‑it‑does cell-communicating ingredient
Sh-Polypeptide-9 is a cell signaling protein also called Vascular Endothelial Growth Factor. As its name suggests, its main function is to stimulate the formation of blood vessels. [more]
what‑it‑does cell-communicating ingredient | moisturizer/humectant
Argireline - famous peptide that's often referred to as "Botox in a jar". In reality, it's nowhere near that powerful, but it can smooth wrinkles to some extent by preventing facial muscles from contracting. [more]
what‑it‑does cell-communicating ingredient | soothing | antioxidant
A copper-peptide complex that has unique wound healing and skin remodelling properties. It's also an anti-inflammatory and antioxidant agent. [more]
what‑it‑does antioxidant | moisturizer/humectant
what‑it‑does antioxidant
A handy multifunctional ingredient that works as a preservative booster, as well as an antioxidant and soothing agent.
what‑it‑does moisturizer/humectant
A "bioengineered" from of skin building block N-acetylglucosamine-6-phosphate (NAG6P). It's claimed to help the skin to synthesize important skin-identical humectants like GAGs and hyaluronic acid. [more]
what‑it‑does moisturizer/humectant
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
what‑it‑does chelating
It’s one of those little helper ingredients that makes sure the product stays the same over time. No color change or anything like that. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.  [more]
what‑it‑does viscosity controlling
A helper ingredient that is used as a bulking and viscosity controlling agent. It is also an emulsion stabilizer in water-in-oil emulsions, where water droplets are dispersed in the continuous oil phase and not the other way round. It can also be used as a heat generating agent in water-less formulas as it has an instant heat-generating chemical reaction with water. [more]
what‑it‑does viscosity controlling
A nice little helper ingredient that can thicken up cosmetic products and create beautiful gel formulas. It's derived from cellulose, the major component of the cell wall of green plants. [more]
what‑it‑does emollient | emulsifying
It's quite the multi-tasker: an emollient and water-binding ingredient but also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes.  [more]
what‑it‑does buffering
An AHA that comes from citrus fruits. It is usually used as a helper ingredient to adjust the pH of the formula. [more]
It's a little helper ingredient coming from corn, rice or potato starch that can help to keep skin mat (absorbent), to stabilise emulsions, and to keep the product together (binding). 
what‑it‑does solvent | moisturizer/humectant
A natural corn sugar derived glycol. It can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. [more]
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0, 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
what‑it‑does solvent | moisturizer/humectant
A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent, and a broad spectrum antimicrobial. [more]
what‑it‑does preservative
It can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too. [more]
what‑it‑does moisturizer/humectant | emollient
A handy multi-tasking ingredient that gives the skin a nice, soft feel and also boosts the effectiveness of other preservatives. [more]
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]