C25 Cream
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Dermaceutic C25 CreamIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
We don't have description for this ingredient yet.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
It's a type of glycol that - according to the manufacturer - is an extremely good replacement for other glycols like propylene or butylene glycol. Its main job is to be a solvent, but it has also very good antimicrobial properties and acts as a true preservative booster. Also helps with skin hydration without stickiness or tacky feel.
A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular.
A super commonly used 5 unit long, cyclic structured silicone that is water-thin and does not stay on the skin but evaporates from it (called volatile silicone). Similar to other silicones, it gives skin and hair a silky, smooth feel.
It's often combined with the non-volatile (i.e. stays on the skin) dimethicone as the two together form a water-resistant, breathable protective barrier on the skin without a negative tacky feel.
An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.
It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols. Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.
We don't have description for this ingredient yet.
A copolymer is a big molecule that consists not of one but of two repeating subunits. This particular copolymer is a handy helper ingredient to form nice gel textures.
It usually comes to the formula combined with emollients (such as C13-14 Isoparaffin, Isohexadecane, Isononyl Isononanoate or Squalane) and can be used as an emulsifier and/or thickener to produce milky gel emulsions with a soft and non-tacky skin feel.
A light-feeling, volatile (meaning it does not absorb into the skin but evaporates from it) silicone that gives skin a unique, silky and non-greasy feel. It has excellent spreading properties and leaves no oily residue or build-up.
A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.
Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.
It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".
A very common water-loving surfactant and emulsifier that helps to keep water and oil mixed nicely together.
It's often paired with glyceryl stearate - the two together form a super effective emulsifier duo that's salt and acid tolerant and works over a wide pH range. It also gives a "pleasing product aesthetics", so no wonder it's popular.
It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version.
According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E.
An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid).
Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier.
Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.
Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation.
If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.
As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily.
It's an ester form of vitamin A (retinol + palmitic acid) that belongs to the "retinoid family". The retinoid family is pretty much the royal family of skincare, with the king being the FDA-approved anti-aging ingredient tretinoin. Retinol is also a very famous member of the family, but it's like Prince George, two steps away from the throne. Retinyl palmitate will be then Prince Charlotte (George's little sister), quite far (3 steps) away from the throne.
By steps, we mean metabolic steps. Tretinoin, aka retinoic acid, is the active ingredient our skin cells can understand and retinyl palmitate (RP) has to be converted by our metabolic machinery to actually do something. The conversion is a 3 step one and looks like this:
retinyl palmitate --> retinol -- > retinaldehyde --> all-trans-retinoic acid
As we wrote in our lengthy retinol description the problem is that the conversion is not terribly effective. The evidence that RP is still an effective anti-aging ingredient is not very strong, in fact, it's weak. Dr. Leslie Baumann in her fantastic Cosmetic Dermatology book writes that RP is topically ineffective.
What's more, the anti-aging effectiveness is not the only questionable thing about RP. It also exibits questionable behaviour in the presence of UV light and was the center of a debate between the non-profit group, EWG (whose intentions are no doubt good, but its credibility is often questioned by scientists) and a group of scientists and dermatologists lead by Steven Q. Wang, MD, director of dermatologic surgery at Memorial-Sloan Kettering Cancer Centre.
Dr. Leslie Baumann wrote a great review of the debate and summarized the research available about retinyl palmitate here. It seems that there is a study showing RP being photo protective against UVB rays but there is also a study showing RP causing DNA damage and cytotoxicity in association with UVA.
We think that the truth lies somewhere in the middle, and we agree with Dr. Baumann's conclusion: "sufficient evidence to establish a causal link between RP and skin cancer has not been produced. Nor, I’m afraid, are there any good reasons to recommend the use of RP". We would add especially during the day!
Bottom line: If you wanna get serious about retinoids, RP is not your ingredient (retinol or tretinoin is!). However, if you use a product that you like and it also contains RP, there is no reason to throw it away. If possible use it at night, just to be on the safe side.
Though its name says acid, it's not really an exfoliant. It's a plant extract with some antioxidant properties. Its main thing in cosmetic products is to neutralize the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. It's a natural alternative to sometimes bad-mouthed chelating agents, EDTAs.
- It’s the second most researched AHA after glycolic acid
- It gently lifts off dead skin cells to reveal newer, fresher, smoother skin
- It also has amazing skin hydrating properties
- In higher concentration (10% and up) it improves skin firmness, thickness and wrinkles
- Choose a product where you know the concentration and pH value because these two greatly influence effectiveness
- Don’t forget to use your sunscreen (in any case but especially so next to an AHA product)
- Primary fat-soluble antioxidant in our skin
- Significant photoprotection against UVB rays
- Vit C + Vit E work in synergy and provide great photoprotection
- Has emollient properties
- Easy to formulate, stable and relatively inexpensive
We don't have description for this ingredient yet.
We wholeheartedly support the rise of seedless grapes as fruit snacks, but when it comes to skincare, we are big fans of the seeds.
They contain the majority of the skin goodies that - similar to green tea - are mostly polyphenols (but not the same ones as in tea). The most abundant ones in grape are called proanthocyanidins, and 60-70% of them are found in the seeds (it's also often abbreviated as GSP - grape seed proanthocyanidins). In general, the darker the fruit, the more GSPs and other flavonoids it contains.
So what's so special about GSPs? Well, they are super-potent antioxidants, much stronger than Vitamin C or Vitamin E. And if that's not enough, GSPs and other flavonoids in grape also show UV protecting and anti-cancer properties.
It's definitely a goodie to spot on the INCI list.
A light, velvety, unique skin feel liquid that is a good solvent and also makes the skin feel nice and smooth (aka emollient). It's often used in makeup products mixed with silicones to give shine and slip to the product. It's also great for cleansing dirt and oil from the skin as well as for taking off make-up.
We don't have description for this ingredient yet.
Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.
BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.
It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive.
It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It can be naturally found in fruits and teas but can also be made synthetically.
No matter the origin, in small amounts (up to 1%) it’s a nice, gentle preservative. Has to be combined with some other nice preservatives, like potassium sorbate to be broad spectrum enough.
In high amounts, it can be a skin irritant, but don’t worry, it’s never used in high amounts.
A common little helper ingredient that helps water and oil to mix together, aka emulsifier.
The number at the end refers to the oil-loving part and the bigger the number the more emulsifying power it has. 20 is a weak emulsifier, rather called solubilizer used commonly in toners while 60 and 80 are more common in serums and creams.
It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It’s not a strong one and doesn’t really work against bacteria, but more against mold and yeast. To do that it has to break down to its active form, sorbic acid. For that to happen, there has to be water in the product and the right pH value (pH 3-4).
But even if everything is right, it’s not enough on its own. If you see potassium sorbate you should see some other preservative next to it too.
BTW, it’s also a food preservative and even has an E number, E202.
A big sugar molecule (polysaccharide) that is used as a natural thickening and gelling agent. It is similar to more commonly used Xanthan Gum, and the two are also often combined to create gel formulas or to stabilize emulsions.
The unfancy name for it is lye. It’s a solid white stuff that’s very alkaline and used in small amounts to adjust the pH of the product and make it just right.
For example, in case of AHA or BHA exfoliants, the right pH is super-duper important, and pH adjusters like sodium hydroxide are needed.
BTW, lye is not something new. It was already used by ancient Egyptians to help oil and fat magically turn into something else. Can you guess what? Yes, it’s soap. It still often shows up in the ingredient list of soaps and other cleansers.
Sodium hydroxide in itself is a potent skin irritant, but once it's reacted (as it is usually in skin care products, like exfoliants) it is totally harmless.
Simply alcohol refers to ethanol and it's a pretty controversial ingredient. It has many instant benefits: it's a great solvent, penetration enhancer, creates cosmetically elegant, light formulas, great astringent and antimicrobial. No wonder it's popular in toners and oily skin formulas.
The downside is that it can be very drying if it's in the first few ingredients on an ingredient list.
Some experts even think that regular exposure to alcohol damages skin barrier and causes inflammation though it's a debated opinion. If you wanna know more, we wrote a more detailed explanation about what's the deal with alcohol in skincare products at alcohol denat. (it's also alcohol, but with some additives to make sure no one drinks it).
A mainly oil-loving, vegetable raw material based ingredient that helps water and oil to mix together, aka emulsifier. It can also function as a wetting and dispersing agent helping insoluble particles such as color pigments or inorganic sunscreens (zinc/titanium dioxide) to disperse nice and even in liquids.
Chemically speaking, it comes from the attachment of sorbitan (a dehydrated sorbitol (sugar) molecule) with the unsaturated fatty acid Oleic Acid, that creates a partly water (the sorbitan part) and partly oil soluble (oleic part) molecule.
A mildly viscous, amber-colored liquid with fatty odor, made from Castor Oil and polyethylene glycol (PEG).
If it were a person, we’d say, it’s agile, diligent & multifunctional. It’s mostly used as an emulsifier and surfactant but most often it is used to solubilize fragrances into water-based formulas.
Linalool is a super common fragrance ingredient. It’s kind of everywhere - both in plants and in cosmetic products. It’s part of 200 natural oils including lavender, ylang-ylang, bergamot, jasmine, geranium and it can be found in 90-95% of prestige perfumes on the market.
The problem with linalool is, that just like limonene it oxidises on air exposure and becomes allergenic. That’s why a product containing linalool that has been opened for several months is more likely to be allergenic than a fresh one.
A study made in the UK with 483 people tested the allergic reaction to 3% oxidised linalool and 2.3% had positive test results.
With a sweet, light and floral scent, Farnesol is a popular fragrancing ingredient to make your cosmetics that bit nicer to use. It starts its life as a colorless liquid that can either be synthetically created or extracted from loads of plants like citronella, neroli, ylang-ylang, and tuberose.
The reason we list it as icky is because Farnesol is one of the “EU 26 fragrances” that has to be labeled separately (and cannot be simply included in the term “fragrance/perfume” on the label) because of allergen potential, so it is best avoided if you have super sensitive skin.
A common fragrance ingredient that has a nice floral scent and also goes by the name Lilial. It is a known fragrance allergen and as of 1st of March 2022, it has been banned in the EU due to animal studies showing a possible link to infertility (in rats - so no need to panic even if you used a product before with Butylphenyl Methylpropional).
A common fragrance ingredient that smells like jasmine. It is one of the “EU 26 fragrances” that has to be labelled separately because of allergen potential. Best to avoid if your skin is sensitive.
A common fragrance ingredient that has a sweet scent somewhere between lily and fruity melon. Can be found in essential oils, such as lavender oil, orange flower oil or ylang-ylang.
In cosmetics, it can be used up to 1%. It’s one of the “EU 26 fragrances” that has to be labelled separately (and cannot be simply included in the term “fragrance/perfume” on the label) because of allergen potential. Best to avoid if your skin is sensitive.
A super common and cheap fragrance ingredient. It's in many plants, e.g. rosemary, eucalyptus, lavender, lemongrass, peppermint and it's the main component (about 50-90%) of the peel oil of citrus fruits.
It does smell nice but the problem is that it oxidizes on air exposure and the resulting stuff is not good for the skin. Oxidized limonene can cause allergic contact dermatitis and counts as a frequent skin sensitizer.
Limonene's nr1 function is definitely being a fragrance component, but there are several studies showing that it's also a penetration enhancer, mainly for oil-loving components.
All in all, limonene has some pros and cons, but - especially if your skin is sensitive - the cons probably outweigh the pros.
It’s a common fragrance ingredient that is one of the “EU 26 fragrances” that has to be labelled separately (and cannot be simply included in the term “fragrance/perfume” on the label) because of allergen potential. Best to avoid if your skin is sensitive.
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
It is typically used in tiny amounts, around 0.1% or less.
Citronellol is a very common fragrance ingredient with a nice rose-like odor. In the UK, it’s actually the third most often listed perfume on the ingredient lists.
It can be naturally found in geranium oil (about 30%) or rose oil (about 25%).
As with all fragrance ingredients, citronellol can also cause allergic contact dermatitis and should be avoided if you have perfume allergy. In a 2001 worldwide study with 178 people with known sensitization to fragrances citronellol tested positive in 5.6% of the cases.
There is no known anti-aging or positive skin benefits of the ingredient. It’s in our products to make it smell nice.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
It’s a common fragrance ingredient that has a light floral smell. It’s one of the “EU 26 fragrances” that has to be labelled separately (and cannot be simply included in the term “fragrance/perfume” on the label) because of allergen potential. Best to avoid if your skin is sensitive.
Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!).
If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.
Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!).
A colorless or yellowish oil that's used as a fragrance. It has a spicy scent and can be found for example in basil, clove or cinnamon oil.
A 2006 in-vitro (made in the lab not on real people) study examined if clove oil is cytotoxic and found that not only clove oil but also its main constituent, eugenol is cytotoxic even at very low concentration (0.03%). It’s also one of the “EU 26 fragrances” that has to be labelled separately (and cannot be simply included in the term “fragrance/perfume” on the label) because of allergen potential. Best to avoid at least in leave-on products.
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| what‑it‑does | solvent |
| what‑it‑does | antioxidant | viscosity controlling |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | emollient |
| what‑it‑does | solvent |
| what‑it‑does | emollient |
| what‑it‑does | emollient | solvent |
| what‑it‑does | emollient | viscosity controlling | emulsifying | surfactant/cleansing |
| irritancy, com. | 1, 2 |
| what‑it‑does | surfactant/cleansing |
| what‑it‑does | viscosity controlling |
| what‑it‑does | emollient | solvent |
| what‑it‑does | emollient | emulsifying |
| irritancy, com. | 0, 1-2 |
| what‑it‑does | surfactant/cleansing | emulsifying |
| irritancy, com. | 0, 0 |
| what‑it‑does | antioxidant |
| irritancy, com. | 0, 0 |
| what‑it‑does | soothing | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | cell-communicating ingredient |
| irritancy, com. | 1-3, 1-3 |
| what‑it‑does | chelating |
| what‑it‑does | exfoliant | moisturizer/humectant | buffering |
| what‑it‑does | antioxidant |
| irritancy, com. | 0-3, 0-3 |
| what‑it‑does | skin brightening |
| what‑it‑does | antioxidant | antimicrobial/antibacterial |
| what‑it‑does | emollient | solvent |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | moisturizer/humectant | solvent |
| irritancy, com. | 0, 1 |
| what‑it‑does | preservative | perfuming | solvent | viscosity controlling |
| what‑it‑does | emulsifying | surfactant/cleansing |
| irritancy, com. | 0, 0 |
| what‑it‑does | preservative |
| what‑it‑does | viscosity controlling |
| what‑it‑does | buffering |
| what‑it‑does | antimicrobial/antibacterial | solvent | viscosity controlling |
| what‑it‑does | emulsifying |
| irritancy, com. | 0, 3 |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | perfuming |
| what‑it‑does | perfuming |
| what‑it‑does | perfuming |
| what‑it‑does | perfuming |
| what‑it‑does | perfuming |
| what‑it‑does | perfuming | solvent |
| what‑it‑does | perfuming |
| what‑it‑does | chelating |
| what‑it‑does | perfuming |
| what‑it‑does | preservative |
| what‑it‑does | perfuming |
| what‑it‑does | perfuming |
| what‑it‑does | perfuming |