|Ingredient name||what-it-does||irr., com.||ID-Rating|
|Potassium Palmitoyl Hydrolyzed Wheat Protein||surfactant/cleansing|
|Glyceryl Stearate||emollient, emulsifying||0, 1-2|
|Cetearyl Alcohol||emollient, viscosity controlling, emulsifying, surfactant/cleansing||1, 2|
|Glyceryl Stearate SE||emulsifying||2, 3|
|Dicaprylyl Ether||emollient, solvent|
|Ethylhexyl Methoxycinnamate||sunscreen||0, 0|
|Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine||sunscreen||goodie|
|Ascorbyl Palmitate||antioxidant||0, 2||icky|
|Tocopheryl Acetate||antioxidant||0, 0|
|Xanthan Gum||viscosity controlling, emulsifying, surfactant/cleansing|
|Alcohol Denat||antimicrobial/antibacterial, solvent, viscosity controlling||icky|
|Caprylyl Glycol||moisturizer/humectant, emollient|
|Potassium Azeloyl Diglycinate||skin brightening, anti-acne, soothing||goodie|
Cetaphil RednesscontrolIngredients explained
We don't have description for this ingredient yet.
A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.
Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.
It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".
An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.
It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols. Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.
An oily kind of ingredient that can magically blend with water all by itself. This is called self-emulsifying and SE in its name stands for that.
The difference between "normal" Glyceryl Stearate and this guy is that the SE grade contains a small amount of water-loving soap molecules, such as sodium stearate. This increases Glyceryl Stearate's affinity for water and gives it stronger emulsifying abilities.
Other than that, it’s a nice emollient that gives a smooth and soft appearance to the skin.
You can read some more at Glyceryl Stearate >>
A clear, colorless and odorless oily liquid that works as a fast-spreading emollient with a dry skin feel.
A clear, oil-soluble, "cosmetically-elegant" liquid that is the most commonly used chemical sunscreen. It absorbs UVB radiation (at wavelengths: 280-320 nm) with a peak protection at 310nm.
It only protects against UVB and not UVA rays (the 320-400 nm range) – so always choose products that contain other sunscreens too. It is not very stable either, when exposed to sunlight, it kind of breaks down and loses its effectiveness (not instantly, but over time - it loses 10% of its SPF protection ability within 35 mins). To make it more stable it can be - and should be - combined with other sunscreen agents to give stable and broad-spectrum protection (the new generation sunscreen agent, Tinosorb S is a particularly good one for that).
Regarding safety, there are also some concerns around Octinoxate. In vitro (made in the lab not on real people) and animal studies have shown that it may produce hormonal (estrogen-like) effects. Do not panic, the studies were not conducted under real life conditions on real human people, so it is probably over-cautious to avoid Octinoxate altogether. However, if you are pregnant or a small child (under 2 yrs. old), choose a physical (zinc oxide/titanium dioxide) or new-generation Tinosorb based sunscreen, just to be on the super-safe side. :)
Overall, Ethylhexyl Methoxycinnamate is an old-school chemical sunscreen agent. There are plenty of better options for sun protection today, but it is considered "safe as used" (and sunscreens are pretty well regulated) and it is available worldwide (can be used up to 10% in the EU and up to 7.5% in the US).
The famous Avobenzone. It is a special snowflake as it is the only globally available chemical sunscreen agent that provides proper UVA protection (in the US, new generation sunscreen agents are not approved because of impossible FDA regulations). It is the global gold standard of UVA protection and is the most used UVA sunscreen in the world.
It gives very good protection across the whole UVA range (310-400 nm that is both UVA1 and UVA2) with a peak protection at 360 nm. The problem with it, though, is that it is not photostable and degrades in the sunlight. Wikipedia says that avobenzone loses 36% of its UV-absorption capacity after just one hour of sunlight (yep, this is one of the reasons why sunscreens have to be reapplied after a few hours).
The cosmetic's industry is trying to solve the problem by combining avobenzone with other UV filters that enhance its stability (like octocrylene, Tinosorb S or Ensulizole) or by encapsulating it and while both solutions help, neither is perfect. Interestingly, the combination of avobenzone with mineral sunscreens (that is titanium dioxide and zinc oxide) is not a good idea. In the US, it is flat out prohibited as avobenzone becomes unstable when combined with mineral sunscreens.
As for safety, avobenzone has a pretty good safety profile. It counts as non-irritating, and unlike some other chemical sunscreens, it shows no estrogenic effect. The maximum concentration of avobenzone permitted is 5% in the EU and 3% in the US.
Its INCI name is a bit of a mouthful, but Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine is worth recognizing it as it is one of the best sunscreen agents known today. Unfortunately, it's not FDA-approved so you will not find it in sunscreens coming from the US (not because it's not good, but because US regulations make it impossible for newer sunscreen agents to get approved), but it is widely available in other parts of the world like Europe, Australia or Asia.
It is a broad-spectrum (covers the whole UVB and UVA range, 280-400 nm) chemical sunscreen agent with peak protections at about 310 and 345 nm and unlike older UV filters, it's very photostable. It hardly deteriorates in the presence of UV light and it's also useful in stabilizing other less stable sunscreen agents, like the famous UVA protector, avobenzone.
It's a new generation sunscreen agent that was specifically designed for high SPF and good UVA protection and based on a 2007 study that compared 18 sunscreen agents available in the EU it really had the best SPF protection (they used the highest concentration allowed by EU regulations from each 18 sunscreens and Trinosorb S gave an SPF 20 all by itself).
It is an oil-soluble, slightly yellowish powder that is not absorbed into the skin too much. This is good news for a sunscreen agent as it needs to be on the surface of the skin to do its job properly. Regarding Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine side effects, we have good news here as well: it has a great safety profile and unlike a couple of other chemical sunscreens, Trinosorb S (and M) does not show estrogenic activity.
Overall, we think Trinosorb S is one of the best sunscreen options available today.
Are you into sunscreen agents? We have shiny explanations (along with product lists) about others as well:
- Methylene Bis-Benzotriazolyl Tetramethylbutylphenol, aka Tinosorb M, the good buddy of our current molecule Tinosorb S
- Tris-Biphenyl Triazine, aka Tinosorb A2B, the newest addition to the Tinosorb family that protects strongly in an in-between wavelength that most other filters miss
- Ethylhexyl Triazone, aka Uvinul T 150, another new generation sunscreen agent with super-high UVB protection
- Diethylamino Hydroxybenzoyl Hexyl Benzoate, aka Uvinul A Plus, a new generation sunscreen for UVA protection
A very common ingredient that can be found in all cell membranes. In cosmetics it's quite the multi-tasker: it's an emollient and water-binding ingredient but it's also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes.
- Primary fat-soluble antioxidant in our skin
- Significant photoprotection against UVB rays
- Vit C + Vit E work in synergy and provide great photoprotection
- Has emollient properties
- Easy to formulate, stable and relatively inexpensive
A form of skincare superstar, vitamin C. Even though we are massive vitamin C fans, Ascorbyl Palmitate (AP) is our least favorite. (Btw, if you do not know what the big deal with vitamin C is then you are missing out. You must go and read our geeky details about it.)
So, AP is one of the attempts by the cosmetics industry to solve the stability issues with vitamin C while preserving its benefits, but it seems to fall short on several things.
What's the problem?
Firstly, it's stability is only similar to that of pure ascorbic acid (AA), which means it is not really stable. A great study in the Journal of Cosmetic Dermatology compared a bunch of vitamin C derivatives and this derivative was the only one where the study said in terms of stability that it's "similar to AA". Not really that good.
Second, a study that examined the skin absorption of vitamin C found that ascorbyl palmitate did not increase the skin levels of AA. This does not mean that ascorbyl palmitate cannot penetrate the skin (because it can, it's oil soluble and the skin likes to absorb oil soluble things) but this means that it's questionable if ascorbyl palmitate can be converted into pure Vit C in the skin. Even if it can be converted, the palmitate part of the molecule is more than the half of it, so the efficacy will not be good and we have never seen a serum that contains a decent (and proudly disclosed) amount of AP. We are highly skeptical what effect a tiny amount of AP has in a formula.
Third, another study that wanted to examine the antioxidant properties of AP was surprised to find that even though AP does have nice antioxidant properties; following UVB radiation (the same one that comes from the sun) it also promotes lipid peroxidation and cytotoxicity. It was only an in-vitro study meaning that it was done on cell cultures and not on real people, but still, this also does not support the use of AP too much.
The only good thing we can write about Ascorbyl Palmitate is that there is an in-vitro (made in the lab, not on real people) study showing that it might be able to boost collagen production.
Regarding the skin-brightening properties of pure vitamin C, this is another magic property AP does not have, or at least there is no data, not even in-vitro, about it.
Overall, Ascorbyl Palmitate is our least favorite vitamin C derivative. It is there in lots of products in tiny amounts (honestly, we do not really understand why), however, we do not know about any vitamin C serum featuring AP in high amounts. That is probably no coincidence. If you are into vitamin C, you can take a look at more promising derivatives here.
Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA.
So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh.
There is also some research showing that citric acid with regular use (think three months and 20% concentration) can help sun-damaged skin, increase skin thickness and some nice hydrating things called glycosaminoglycans in the skin.
But according to a comparative study done in 1995, citric acid has less skin improving magic properties than glycolic or lactic acid. Probably that’s why citric acid is usually not used as an exfoliant but more as a helper ingredient in small amounts to adjust the pH of a formulation.
It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version.
According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E.
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
We don't have description for this ingredient yet.
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
- It's a super common and super debated skincare ingredient
- It has several benefits: great solvent, penetration enhancer, creates cosmetically elegant, light formulas, great astringent and antimicrobial
- It can be very drying if it's in the first few ingredients on an ingredient list
- Some experts even think that regular exposure to alcohol damages skin barrier and causes inflammation though it's a debated opinion (read more in geeky details tab)
A colorless liquid used in small amounts as a so-called masking ingredient, meaning it can hide the natural not-so-nice smell of other cosmetic ingredients. It has a nice rose-like scent and can be found in several essential oils such as rose, neroli or geranium. It also has some antimicrobial activity and can boost the performance of traditional preservatives.
It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol.
The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.
A derivative of clinically proven, superstar ingredient Azelaic Acid and hydrating amino acid Glycine. Azelaic acid is an awesome ingredient with anti-inflammatory, skin lightening and anti-acne effects, but its insolubility (it's soluble neither in water nor in oil) makes it difficult to use it in a cosmetically elegant and versatile way.
The solution is supposed to be Potassium Azeloyl Diglycinate, at least according to the manufacturer. The derivative is very water soluble, easy to use in nice formulas and inherits all the lovely properties of Azelaic acid. It acts as a skin brightening agent via Tyrosinase (a famous enzyme needed to make melanin) inhibition and also has significant sebum normalizing activity.
Regarding research, we could find two studies where Potassium Azeloyl Diglycinate's name popped up. One study examined the management of rosacea and the other one researched the treatment of melasma. Both were successful (we mean people showed improvement :)) but our Azelaic acid derivative was combined with other actives so it's hard to know what to attribute to this guy only.
Overall, a promising multi-function active that's worth checking out if you have pigmentation-prone, acne-prone or rosacea-prone skin.
|what‑it‑does||emollient | emulsifying|
|irritancy, com.||0, 1-2|
|what‑it‑does||emollient | viscosity controlling | emulsifying | surfactant/cleansing|
|irritancy, com.||1, 2|
|irritancy, com.||2, 3|
|what‑it‑does||emollient | solvent|
|irritancy, com.||0, 0|
|what‑it‑does||emollient | emulsifying|
|irritancy, com.||0-3, 0-3|
|irritancy, com.||0, 2|
|irritancy, com.||0, 0|
|what‑it‑does||viscosity controlling | emulsifying | surfactant/cleansing|
|what‑it‑does||antimicrobial/antibacterial | solvent | viscosity controlling|
|what‑it‑does||moisturizer/humectant | emollient|
|what‑it‑does||skin brightening | anti-acne | soothing|