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MEDICARE Hydrant Day

MEDICARE
Hydrant Day

Light and powerful daily moisturizer help combat skin ageing.
Uploaded by: flipper on

Ingredients overview

MEDICARE Hydrant Day
Ingredients explained

Aqua (Water)
Also-called: Water | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

C12-C15 Alkyl Benzoate
What-it-does: emollient, antimicrobial/antibacterial

An often used emollient with a light and silky feel. It's very mild to both skin and eyes and spreads nicely and easily. It's often used in sunscreens as it's also an excellent solvent for sunscreen agents. 

Saccharide Isomerate - goodie
What-it-does: moisturizer/humectant

A 100% natural and plant-derived moisturizer that mimics the natural carbohydrate fraction found in the upper layer of the skin. Its special magic power is to bind to the skin stronger and longer than other moisturizer ingredients do so it can keep the skin hydrated longer than usual.

Biosaccharide Gum-1 - goodie
What-it-does: soothing, moisturizer/humectant

Biosaccharide Gum-1 is a pretty interesting kind of sugar ingredient that is created from sorbitol via bacterial fermentation. 

According to the manufacturer it’s a “S.M.A.R.T.” sugar: it has Soothing, Moisturizing, Anti-aging, Restructuring and Touch properties. Let’s look at them quickly one by one.

Soothing: the manufacturer tested out the soothing effect in vivo (meaning on humans that is always a good thing!) by measuring how 3% Biosaccharide Gum-1 decreased the tingling sensation caused by 10% lactic acid. The result was good: the tingling was decreased by 47%.

Moisturizing: Compared to famous hyaluronic acid, it turns out that the two are great together. HA has a quicker effect and provides more instant hydration (much more hydration was measured after 1h of application), while our nice sugar has a somewhat delayed effect demonstrating stronger hydration after 3h of application. After 8 hours both had similar moisturizing effect. 

Anti-aging: According to ex-vivo tests (meaning not on humans, so do not trust it too much) Biosaccharide Gum-1 can stimulate a protein in our skin called sirtuin-1. This is supposed to help our skin cells to live longer, and function better. 

Resurfacing:  The sirtuin-1 stimulation also results in quicker cell renewal - something that happens anyway but slows down as we age. And the quicker cell renewal is good because it helps the regeneration of the barrier function. That is especially nice for fragile, sensitive skin.

Touch: our fermented sugar is not only good to the skin, but it also feels great on the skin. It gives a nice “soft touch” feeling and makes the products pleasant to use. 

The bottom line is that the above info is from the manufacturer (and we could not find any relevant independent research) so obviously take it with a grain of salt. But Biosaccharide Gum-1 does look as an interesting and promising ingredient that’s why it earned our goodie rating. 

Ethylhexyl Methoxycinnamate
Also-called: Octinoxate, Octyl Methoxycinnamate | What-it-does: sunscreen | Irritancy: 0 | Comedogenicity: 0

A clear, oil-soluble, "cosmetically-elegant" liquid that is the most commonly used chemical sunscreen. It absorbs UVB radiation (at wavelengths: 280-320 nm) with a peak protection at 310nm. 

It only protects against UVB and not UVA rays (the 320-400 nm range) – so always choose products that contain other sunscreens too. It is not very stable either, when exposed to sunlight, it kind of breaks down and loses its effectiveness (not instantly, but over time - it loses 10% of its SPF protection ability within 35 mins). To make it more stable it can be - and should be - combined with other sunscreen agents to give stable and broad-spectrum protection (the new generation sunscreen agent, Tinosorb S is a particularly good one for that).

Regarding safety, there are also some concerns around Octinoxate. In vitro (made in the lab not on real people) and animal studies have shown that it may produce hormonal (estrogen-like) effects. Do not panic, the studies were not conducted under real life conditions on real human people, so it is probably over-cautious to avoid Octinoxate altogether. However, if you are pregnant or a small child (under 2 yrs. old), choose a physical (zinc oxide/titanium dioxide) or new-generation Tinosorb based sunscreen, just to be on the super-safe side. :) 

Overall, Ethylhexyl Methoxycinnamate is an old-school chemical sunscreen agent. There are plenty of better options for sun protection today, but it is considered "safe as used" (and sunscreens are pretty well regulated) and it is available worldwide (can be used up to 10% in the EU and up to 7.5% in the US).

Glyceryl Polyacrylate

We don't have description for this ingredient yet.

Wheat Germ Oil
Also-called: Triticum Vulgare Germ Oil | What-it-does: emollient, moisturizer/humectant

We don't have description for this ingredient yet.

Cyclomethicone
What-it-does: emollient, moisturizer/humectant, solvent, viscosity controlling | Irritancy: 0 | Comedogenicity: 0

Cyclomethicone is not one type of silicone, but a whole mixture of them: it's a mix of specific chain length (4 to 7) cyclic structured silicone molecules. (There seems to be a confusion on the internet whether Cyclomethicone and Cyclopentasiloxane are the same. They are not the same, but Cyclopentasiloxane is part of the mixture that makes up Cyclomethicone). 

All the silicones in the Cyclomethicone mixture are volatile, meaning they evaporate from the skin or hair rather than stay on it. This means that Cyclomethicone has a light skin feel with none-to-minimal after-feel.  It also makes the formulas easy to spread and has nice emollient properties.

Polyacrylamide
What-it-does: viscosity controlling

It's a film-forming and thickening polymer (a large molecule composed of many repeated subunits) that comes to the formula usually as part of an emulsifier, thickener trio (with C13-14 Isoparaffin and Laureth-7, trade named Sepigel 305). This trio is an easy-to-use liquid that helps to create nice, non-tacky gel formulas. 

Beta-Glucan - goodie
What-it-does: soothing, moisturizer/humectant

Beta-Glucan is a nice big molecule composed of many smaller sugar molecules (called polysaccharide). It’s in the cell walls of yeast, some mushrooms, seaweeds, and cereals.

It’s a real goodie no matter if you eat it or put it on your face. Eating it is anti-diabetic, anti-cancer, and even lowers blood cholesterol. 

Putting it on your face also does a bunch of good things: it‘s shown to have wound healing properties, it’s a mild antioxidant, a great skin soother, and moisturizer, and it even shows promising anti-aging benefits. 

The manufacturer of the ingredient did a published study with 27 people and examined the effect of 0.1% beta-glucan. They found that despite the large molecular size beta-glucan does penetrate into the skin, even into the dermis (the middle layer of the skin where wrinkles form). After 8 weeks there was a significant reduction of wrinkle depth and height and skin roughness has also improved greatly. 

Bottom line: Beta-glucan is a great ingredient, especially for sensitive skin. It soothes, moisturizes, and has some anti-aging magic properties. 

Ectoin - goodie
Also-called: 28Extremoin

We don't have description for this ingredient yet.

Superoxide Dismutase - goodie
Also-called: SOD | What-it-does: antioxidant

Superoxide Dismutase - or in short SOD - is the body's smart antioxidant enzyme that protects the cells from highly reactive, cell-damaging superoxide radicals (O2−).

You have probably read the terms "free radicals" and "antioxidants" a thousand times, and you know that free radicals are the evil guys, and antioxidants are the good guys. So superoxide radical is a very common free radical that can cause all kinds of cell damages and superoxide dismutase is an enzyme that catalyzes the conversion of superoxide radicals into molecular oxygen and hydrogen peroxide (btw, this one has to be further converted by other antioxidant enzymes, called catalases).

The extra nice thing about SOD is that it remains intact during the neutralization process and can continue its magic, while non-enzymatic antioxidants (like vitamin E) are used up during neutralization.

The efficacy studies of topical SOD are promising. In-vitro (made in the lab) tests show that SOD is a more effective antioxidant than vitamin E, green tea extract, and MAP. There is also an in-vivo (made on real people) study that measured how SOD can reduce the redness caused by UV rays and it was much more effective than vitamin E (pure or acetate form) and ascorbyl palmitate. 

All in all, SOD is a really potent antioxidant and slathering it all over yourself is a great way to give the skin a little extra help in protecting itself from all the bad environmental things out there. 

Tocopherol Acetate
Also-called: Vitamin E Acetate;Tocopheryl Acetate | What-it-does: antioxidant | Irritancy: 0 | Comedogenicity: 0

It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version. 

According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E. 

Cetearyl Isononanoate
What-it-does: emollient

It's a clear, slightly yellowish oil (comes from coconut or palm kernel oil) that is used as a traditional, medium spreading emollient. 

Benzophenone-3 - icky
Also-called: Oxybenzone | What-it-does: sunscreen | Irritancy: 0 | Comedogenicity: 0

A chemical sunscreen agent that absorbs UVB and short UVA rays (280-350nm) with its peak protection at 288 nm. Unlike many other chemical sunscreens, it is highly stable but its UV absorbing abilities are weak so it always has to be combined with other sunscreen agents for proper protection. More often than not, it's used as a photostabilizer rather than a proper sunscreen agent as it can protect formulas nicely from UV damage.

Regarding safety, BP-3 is somewhat controversial. First, its molecules are small (228 Da) and very lipophilic (oil loving) and these properties result in very good absorption. The problem is that you want sunscreens on the top of your skin and not in your bloodstream, so for BP-3 this is a problem. In fact, it absorbs so well that 4 hours after application of a sunscreen product with BP-3, it can be detected in urine. 

Another concern of BP-3 is that it shows some estrogenic activity, though it's probably not relevant when applied topically to the skin. Estrogenic activity was confirmed only in-vitro (in test tubes) and when taken orally by lab animals, and not when used topically as you would normally. In fact, a 2004 follow-up study to examine the estrogenic effect of sunscreens when used topically on the whole body found that "the endogenous levels of reproductive hormones were unaffected" (even though BP-3 could be detected both in plasma and urine, so its absorption is no doubt too good).

If that was not enough, Wikipedia claims that BP-3 is nowadays the most common allergen found in sunscreens, and the always-trustworthy smartskincare writes that "[benzophenones] have been shown in some studies to promote the generation of potentially harmful free radicals".

On the up side, sunscreens are pretty well regulated in several parts of the world, and BP-3 is considered "safe as used" and is an allowed sunscreen agent everywhere. It can be used in concentrations of up to 10% in the EU and up to 6% in the US.

Overall, BP-3 is probably our least favorite sunscreen agent and we prefer sunscreens without it. However, if you find a formula that you love and contains BP-3, we do not think that you should throw it away. A sunscreen with BP-3 is definitely better than no sunscreen. 

Caprylic-Capric-Triglyceride
What-it-does: emollient

A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular. 

2-Bromo-2 Nitropropane-3 Diol
What-it-does: preservative

We don't have description for this ingredient yet.

Hydrolyzed Collagen - goodie
What-it-does: emollient, moisturizer/humectant

The chemically chopped up version of the big protein molecule, collagen. It is often derived from fish or bovine sources and works as a nice moisturizer and humectant that helps the skin to hold onto water.  

To understand a bit more what Hydrolyzed Collagen is, you have to know that proteins are large chains of amino acids connected with so-called peptide bonds. These bonds can be broken up when a water molecule is added and the resulting thing is a mix of shorter length amino acids, also called peptides. So Hydrolyzed Collagen is not really collagen, it is rather an undefined and varying mix of largish peptides. Based on a manufacturer's data, the whole, soluble collagen has an average molecular weight of 300 000 Da, while this chopped up mixture has an average MW of 12 000 Da (still pretty big). 

The main thing of these largish peptides is to act as water-binding agents, and to make the skin nice and smooth (aka emollient). Hydrolyzed Collagen is also often used in cleansers as it can make harsh surfactants milder and in hair conditioners as it improves the flexibility and manageability of hair. 

If you wanna know more about collagen in cosmetics, we have a shiny explanation about soluble collagen here >> 

Elastin

We don't have description for this ingredient yet.

Phenoxyethanol
What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10). 

It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.

Polysilicone-8

We don't have description for this ingredient yet.

Hyaluronic Acid - goodie
What-it-does: skin-identical ingredient, moisturizer/humectant
  • It’s naturally in our skin and behaves there like a sponge
  • It can bind up to 1000 times its own weight in water
  • It is a big molecule from repeated subunits (polymer) so different molecular weight versions exist (unfortunately there is no way to determine MW from INCI list only)
  • High-molecular-weight-HA (>500 kDa) is an excellent surface hydrator, skin protectant and can act as an osmotic pump helping water-soluble actives to penetrate deeper into the skin
  • Low-molecular-weight-HA (< 500 kDa) can hydrate the skin somewhat deeper though it is still a big molecule and works mainly in the epidermis (outer layer of the skin)
  • Low-molecular-weight-HA might also help the skin to repair itself by increasing its self-defense (~ 200kDa used in the study)
  • Ultra-low-molecular-weight-HA (<50kDa) is a controversial ingredient and might work as a pro-inflammatory signal molecule
Read all the geeky details about Hyaluronic Acid here >>

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot)
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

Aminobutyric Acid

We don't have description for this ingredient yet.

Magnesium Ascorbyl Phosphate - goodie
Also-called: Form of Vitamin C, MAP | What-it-does: skin brightening, antioxidant

A form of skincare superstar, Vitamin C. If you do not know, what the big deal about Vitamin C is, click here and read all about it, we will wait here for you. 

So now you know that pure vitamin C (aka ascorbic acid, AA) is really unstable and hard to formulate so the cosmetics industry is coming up with a bunch of derivatives to solve the problem and Magnesium Ascorbyl Phosphate (or MAP) is one of them.  

MAP does solve the stability problem: it's stable up to pH 7, so far so good. What is not so good is that, as the great review study about vitamin C derivatives in the Journal of Cosmetic Dermatology writes, MAP is "at very best, poorly absorbed in comparison to AA." 

Moreover,  derivatives not only have to be absorbed into the skin, they also have to be converted into pure AA. The good news is that in-vitro data shows that MAP does convert, but the bad news is we do not really know if the same is true on real, living human skin. Even if it does, we don't know how good the conversion rate is (but to be fair the same is true for all other derivatives).

Regarding the three magic abilities of pure vitamin C (antioxidant, collagen booster, skin brightener), there is no published data about MAP's antioxidant or photoprotection capabilities. We have better news about the other two things: in-vitro data shows that MAP can boost collagen synthesis similar to AA (though in the case of AA it's proven in-vivo) and even better, MAP is proven to work as a skin brightener in-vivo (on real people). 

Bottom line: when it comes to vitamin C derivatives, MAP is definitely an option. We especially recommend it if you are after skin brightening as this seems to be the strongest point of MAP. 

 

Centella Asiatica Extract (Gotu Kola) - goodie
Also-called: Gotu Kola, Tiger Grass | What-it-does: soothing, antioxidant, moisturizer/humectant

Centella Asiatica - or gotu kola as normal people call it  - has been used in folk medicine for hundreds of years. It’s traditionally used to improve small wounds, burns and scratches and it’s also a well known anti-inflammatory agent for eczema.

Recently science has taken an interest in Gotu Kola as well and it turns out it really has many active compounds with several benefits. Just for hard-core geeks, the main biologically active compounds are pentacyclic triterpenoid saponins called asiaticoside, madecassoside, asiatic and madecassic acid (also called centellosides).

One of the biological activities of the centellosides is to be able to stimulate GAGs  (glycosaminoglycans - polysaccharides that are part of the liquidy stuff between our skin cells), and especially hyaluronic acid synthesis in our skin. This is probably one of the reasons why Centella Asiatica Extract has nice skin moisturizing properties that was confirmed by a 25 people, four weeks study along with Centella's anti-inflammatory effects.

Madecassoside can also help in burn wound healing through increasing antioxidant activity and enhancing collagen synthesis. Asiaticoside was shown to increase antioxidant levels on rats skin when applied at 0.2%. 

Centella Asiatica also often shows up in products that try to treat cellulite or striae. Of course, it cannot make a miracle but it might have some effect via regulating microcirculation and normalizing the metabolism in the cells of connective tissues. 

Bottom line: Gotu Kola is a great plant ingredient with proven wound healing, anti-inflammatory, and antioxidant properties. Nice to spot on any ingredient list.  

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does emollient | antimicrobial/antibacterial
An often used emollient with a light and silky feel. It's very mild to both skin and eyes and spreads nicely and easily. It's often used in sunscreens as it's also an excellent solvent for sunscreen agents. 
what‑it‑does moisturizer/humectant
A natural moisturizer that can bind to the skin stronger and longer than other similar ingredients so it can keep the skin hydrated longer than usual. [more]
what‑it‑does soothing | moisturizer/humectant
Biosaccharide Gum-1 is a pretty interesting kind of sugar ingredient that is created from sorbitol via bacterial fermentation.  According to the manufacturer it’s a “S.M.A.R.T.” sugar: [more]
what‑it‑does sunscreen
irritancy, com. 0, 0
Octinoxate - an old-school chemical sunscreen that absorbs UVB radiation (wavelengths: 280-320 nm). Not photostable and does not protect against UVA. [more]
what‑it‑does emollient | moisturizer/humectant
what‑it‑does emollient | moisturizer/humectant | solvent | viscosity controlling
irritancy, com. 0, 0
A mixture of 4 to 7 chain length cyclic silicones. It's a light, volatile ingredient that gives skin or hair a smooth feel and has emollient properties. [more]
what‑it‑does viscosity controlling
A film-forming and thickening polymer (a large molecule composed of many repeated subunits) that comes to the formula usually as part of an emulsifier, thickener trio. [more]
what‑it‑does soothing | moisturizer/humectant
A great skin soother and moisturizer, and it even shows promising anti-aging benefits. It‘s also shown to have wound healing properties and is a mild antioxidant. [more]
what‑it‑does antioxidant
Superoxide Dismutase - or in short SOD - is the body's smart antioxidant enzyme that protects the cells from highly reactive, cell-damaging superoxide radicals (O2−). You have probably read the terms "free radicals" [more]
what‑it‑does antioxidant
irritancy, com. 0, 0
A form of vitamin E that works as an antioxidant. Compared to the pure form it's more stable, has longer shelf life, but it's also more poorly absorbed by the skin. [more]
what‑it‑does emollient
A clear, slightly yellowish oil (comes from coconut or palm kernel oil) that is used as a traditional, medium spreading emollient.
what‑it‑does sunscreen
irritancy, com. 0, 0
A chemical sunscreen agent that absorbs UVB and short UVA rays (280-350nm). It's a highly stable but weak UVB absorber, that's often used as a photostabilizer in non-sunscreen proudcts. [more]
what‑it‑does emollient
A very common emollient that makes your skin feel nice and smooth. Comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. [more]
what‑it‑does preservative
what‑it‑does emollient | moisturizer/humectant
The chemically chopped up version of the big protein molecule, collagen. It is often derived from fish or bovine sources and works as a nice moisturizer and humectant that helps the skin to hold onto water.   To understand a bit more what Hydrolyzed Collagen is, you have to know that proteins are large chains of amino acids connected with so-called peptide bonds. [more]
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
A famous natural moisturizing factor that can bind up to 1000 times its own weight in water. Works as an excellent surface hydrator in skincare. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
what‑it‑does skin brightening | antioxidant
A form of skincare superstar, Vitamin C - it has proven skin-brightening abilities (in-vivo) and it might be able to boost collagen production as well (in-vitro). [more]
what‑it‑does soothing | antioxidant | moisturizer/humectant
Centella Asiatica - or gotu kola as normal people call it  - has been used in folk medicine for hundreds of years. It’s traditionally used to improve small wounds, burns and scratches and it’s also a well known anti-inflammatory agent for eczema. Recently science has taken an interest in Gotu Kola as well and it turns out it really has many active compounds with several benefits [more]
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