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Frankly Closer Pore Reducing Serum

Closer Pore Reducing Serum

Peptides are the building blocks of our bodies’ amino acids and proteins. They naturally occur in the skin, but they’re also a well-known skincare ingredient because of the many benefits it has. For one, peptides stimulate the skin’s collagen production, leading to reduced wrinkles and tighter pores.
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Skim through

Ingredient name what-it-does irr., com. ID-Rating
Water solvent
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Butylene Glycol moisturizer/​humectant, solvent 0, 1
Propanediol solvent, moisturizer/​humectant
1,2-Hexanediol solvent
Hydrolyzed Lupine Protein
Acetyl Hexapeptide-8 cell-communicating ingredient, moisturizer/​humectant goodie
Tripeptide-3
Acetyl Octapeptide-3 cell-communicating ingredient, moisturizer/​humectant goodie
Copper Tripeptide-1 cell-communicating ingredient, soothing, antioxidant goodie
Palmitoyl Pentapeptide-4 cell-communicating ingredient goodie
Palmitoyl Tetrapeptide-7 cell-communicating ingredient goodie
Palmitoyl Tripeptide-1 cell-communicating ingredient goodie
Tripeptide-1 cell-communicating ingredient goodie
Tripeptide-2
Adenosine cell-communicating ingredient goodie
Gluconolactone exfoliant, chelating superstar
Collagen moisturizer/​humectant goodie
Hydrolyzed Collagen emollient, moisturizer/​humectant goodie
Leuconostoc/Radish Root Ferment Filtrate antimicrobial/​antibacterial, preservative
Sodium Hyaluronate skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Hydroxyacetophenone antioxidant
Carbomer viscosity controlling 0, 1
Cellulose Gum viscosity controlling 0, 0
Tromethamine buffering
Betaine moisturizer/​humectant goodie
Xanthan Gum viscosity controlling
Ethylhexylglycerin preservative
Hydrolyzed Gardenia Florida Extract antioxidant
Hydrolyzed Malt Extract
Hydrolyzed Viola Tricolor Extract
Disodium EDTA chelating

Frankly Closer Pore Reducing Serum
Ingredients explained

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

Also-called: Zemea | What-it-does: solvent, moisturizer/humectant

Propanediol is a natural alternative for the often used and often bad-mouthed propylene glycol. It's produced sustainably from corn sugar and it's Ecocert approved. 

It's quite a multi-tasker: can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. 

What-it-does: solvent

A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives

We don't have description for this ingredient yet.

Also-called: Argireline, Acetyl Hexapeptide-3 | What-it-does: cell-communicating ingredient, moisturizer/humectant

If you see a cosmetic product that claims that it has "Botox-like effect" then two things are almost certain: one, the product overpromises and two, it contains Argireline. 

So this one is the famous peptide that's marketed by its manufacturer as the "Botox in a jar". The basis for this claim is that it targets the same wrinkle forming mechanism (wrinkles caused by facial muscle movement) as Botox, but the way it works is very different. In addition, the extent to which it can prevent muscles from contracting (and to smooth wrinkles) is very different (otherwise why would anyone use still Botox?). 

We don't have description for this ingredient yet.

Also-called: SNAP-8, Acetyl Glutamyl Heptapeptide-1 | What-it-does: cell-communicating ingredient, moisturizer/humectant

A newer and, molecule-wise, somewhat bigger version of the famous "Botox-like" peptide called Acetyl Hexapeptide-8 or Argireline. Just like Argireline, Acetyl Octapeptide-3 is also claimed to influence the muscle contraction process that results in a more relaxed and line-free face, especially around the forehead and the eyes.  

While Argireline counts as a pretty well-proven peptide, with multiple studies confirming its anti-wrinkle efficacy, we cannot say the same for Acetyl Octapeptide-3. What we have is the manufacturer's claim that comparing 10% Argireline with 10% SNAP-8 solution (that means 0.005% pure peptide powder) the SNAP-8 peptide did a bit better as it reduced wrinkles by 34.98% vs 27.05% reduction for Argireline (twice a day use for 28 days on 17 women). 

Also-called: GHK-Cu, Copper Peptide | What-it-does: cell-communicating ingredient, soothing, antioxidant
  • GHK-Cu is a copper-peptide complex found naturally in yucky bodily fluids (plasma, saliva, and urine)
  • It has unique wound healing properties by stimulating the breakdown of unhealthy, too large collagen in scar tissue and stimulating nice and healthy collagen production afterwards
  • It stimulates the production of several important skin-identical ingredients (e.g. collagen, elastin, and glycosaminoglycans)
  • It has significant anti-inflammatory and antioxidant effect
  • There are a few promising studies showing GHK-Cu can improve skin elasticity, clarity, firmness and reduce lines and wrinkles
  • It can improve hair growth by enlarging hair follicles (and bigger follicles produce longer, thicker hair)
  • There are some urban legends about possible overdosing or facial hair problems (read more in geeky details)
Read all the geeky details about Copper Tripeptide-1 here >>

Also-called: Matrixyl, Pal-KTTKS, Formerly Palmitoyl Pentapeptide-3 | What-it-does: cell-communicating ingredient

A pretty famous and better-researched peptide consisting of five amino acids (the building blocks of all proteins). It was created in a joint effort by the French ingredient supplier, Sederma and the cosmetics industry big shot, Procter&Gamble.

The amino acid sequence of the peptide is lysine–threonine–threonine–lysine–serine (KTTKS). Sometimes, it's also called collagen pentapeptide, as it's a subfragment of skin-structure-giving type I collagen. The KTTKS amino sequence is then attached for better oil solubility and skin penetration to palmitic acid and BOOM; we get Palmitoyl Pentapeptide-4. 

Also-called: Part of Matrixyl 3000, Pal-GQPR, Previously Palmitoyl Tetrapeptide-3 | What-it-does: cell-communicating ingredient

A four amino acid peptide with the amino sequence of glycine-glutamine-proline-arginine. It is attached to palmitic acid (a fatty acid)  to increase oil solubility and skin penetration. 

It works by reducing the production of the signal moleculeinterleukin-6 (IL-6) which promotes inflammation in the skin and less inflammation means slower degradation of important things (like collagen) that results in younger looking skin for a longer time. 

Also-called: Part of Matrixyl 3000, Pal-GHK, Formerly also Palmitoyl Oligopeptide | What-it-does: cell-communicating ingredient

A really famous peptide that is part of Matrixyl 3000, the most sold peptide complex in the word. Before we go and find out what the big deal with Matrixyl 3000 is, let's just focus on Palmitoyl Tripeptide-1 itself for a bit.

It's a small three amino acid (they are the building blocks of all proteins) peptide with the amino sequence of glycine-histidine-lysine, or GHK. GHK is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration. 

Tripeptide-1 - goodie
Also-called: GHK, Kollaren | What-it-does: cell-communicating ingredient

A small, three amino acid (glycine-histidine-lysine or GHK) peptide that is famous for being a type I collagen fragment. The theory behind collagen-fragment peptides is that when collagen naturally breaks down in the skin, the resulting peptide fragments signal to the skin that it should get to work and create some nice, new collagen.

Adding in collagen fragment peptides, like GHK, might trick the skin into thinking that collagen has broken down and it's time to create some more. So Tripeptide-1 is believed to be able to stimulate collagen production in the skin, and more collagen means fewer wrinkles and younger looking skin. FYI; Tripeptide-1 is the same peptide that can be found in the famous Matrixyl 3000, but in Matrixyl a palmitic acid is attached to it to increase its oil solubility and thus skin penetration.

We don't have description for this ingredient yet.

Adenosine - goodie

Adenosine is an important little compound in our body that has a vital cell-signalling role. Research on smearing it on our face is also promising and shows so far a couple of things:

  • It can help with wound healing
  • It’s a good anti-inflammatory agent
  • It might even help with skin’s own collagen production and improve skin firmness and elasticity
  • It helps with barrier repair and protection
  • It might be even useful for the hair helping with hair thickness and hair growth
Gluconolactone - superstar
What-it-does: exfoliant, chelating
  • It’s a polyhydroxy acid (PHA), that is often referred to as next generation AHA
  • It gently lifts off dead skin cells form the skin surface making skin smooth and even
  • In the long term it provides anti-aging benefits, like increased skin thickness and decreased wrinkles (though a tad less than even more proven superstar AHAs)
  • It’s a great moisturizer and even helps to repair impaired skin barrier
  • It’s antioxidant, and does not make your skin more sensitive to the sun
  • It can be used even if your skin is very sensitive, rosacea prone or if you are post cosmetic procedure
Read all the geeky details about Gluconolactone here >>

Collagen - goodie
What-it-does: moisturizer/humectant

The big and important protein molecule that usually comes from animal skin such as fish or bovine. The gist of the "collagen in topical skincare" subject is to know that collagen in a jar has nothing to do with wrinkles but everything to do with skin hydration. We have a shiny explanation about this at soluble collagen, so click here to read more >> 

The chemically chopped up version of the big protein molecule, collagen. It is often derived from fish or bovine sources and works as a nice moisturizer and humectant that helps the skin to hold onto water.  

To understand a bit more what Hydrolyzed Collagen is, you have to know that proteins are large chains of amino acids connected with so-called peptide bonds. These bonds can be broken up when a water molecule is added and the resulting thing is a mix of shorter length amino acids, also called peptides. So Hydrolyzed Collagen is not really collagen, it is rather an undefined and varying mix of largish peptides. Based on a manufacturer's data, the whole, soluble collagen has an average molecular weight of 300 000 Da, while this chopped up mixture has an average MW of 12 000 Da (still pretty big). 

Also-called: Fermented Radish Root | What-it-does: antimicrobial/antibacterial, preservative

It's an alternative, natural preservative that comes from radishes fermented with Leuconostoc kimchii, a lactic acid bacteria that has been used to make traditional Korean dish, kimchi. During the fermentation process, a peptide is secreted from the bacteria that has significant antimicrobial properties

It is one of the more promising natural preservatives that can be used even alone (recommended at 2-4%), but it's not as effective as more common alternatives, like parabens or phenoxyethanol

What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0

It’s the - sodium form - cousin of the famous NMFhyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

What-it-does: antioxidant

A handy multifunctional ingredient that works as a preservative booster, as well as an antioxidant and soothing agent

What-it-does: viscosity controlling, emulsion stabilising | Irritancy: 0 | Comedogenicity: 1

A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula.  It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.

Also-called: Carboxymethyl Cellulose | What-it-does: viscosity controlling, emulsion stabilising | Irritancy: 0 | Comedogenicity: 0

A cellulose (the big molecule found in the cell wall of green plants) derivative that is used as an emulsion stabilizer and thickener

What-it-does: buffering

It's a little helper ingredient that helps to set the pH of the products to be right. It has an alkaline pH and can neutralize acidic ingredients.

Betaine - goodie
What-it-does: moisturizer/humectant

A sugar beet-derived amino acid derivative with nice skin protection and moisturization properties. Betaine's special thing is being an osmolyte, a molecule that helps to control cell-water balance.  It is also a natural osmoprotectant, meaning that it attracts water away from the protein surface and thus protects them from denaturation and increases their thermodynamic stability. 

It also gives sensorial benefits to the formula and when used in cleansers, it helps to make them milder and gentler. 

It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range. 

Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415). 

What-it-does: preservative, deodorant

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient

What-it-does: antioxidant

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

What-it-does: chelating

Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.

It is typically used in tiny amounts, around 0.1% or less.

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0, 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
what‑it‑does solvent | moisturizer/humectant
A natural corn sugar derived glycol. It can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. [more]
what‑it‑does solvent
A multi-functional helper ingredient that acts as a humectant and emollient. It's also a solvent and can boost the effectiveness of preservatives. [more]
what‑it‑does cell-communicating ingredient | moisturizer/humectant
Argireline - famous peptide that's often referred to as "Botox in a jar". In reality, it's nowhere near that powerful, but it can smooth wrinkles to some extent by preventing facial muscles from contracting. [more]
what‑it‑does cell-communicating ingredient | moisturizer/humectant
A newer and molecule-wise somewhat bigger version of famous "Botox-like" peptide, Argireline. It is also claimed to influence the muscle contraction process that results in a more relaxed and line-free face. [more]
what‑it‑does cell-communicating ingredient | soothing | antioxidant
A copper-peptide complex that has unique wound healing and skin remodelling properties. It's also an anti-inflammatory and antioxidant agent. [more]
what‑it‑does cell-communicating ingredient
Matrixyl - A 5 amino acid peptide with promising research showing that it can reduce fine lines, wrinkles and improve skin texture. [more]
what‑it‑does cell-communicating ingredient
The pal of Palmitoyl Tripeptide-1 in Matrixyl 3000. A four amino acid peptide that works by reducing the production of the signal molecule, inteleukin-6 (IL-6) that promotes inflammation in the skin. [more]
what‑it‑does cell-communicating ingredient
A three amino acid peptide that is part of famous peptide duo, Matrixyl 3000. It's a type I collagen fragment that might be able to trick the skin to think that collagen broke down and it's time to create some new one. [more]
what‑it‑does cell-communicating ingredient
A small, three amino acid (glycine-histidine-lysine or GHK) peptide that is famous for being a type I collagen fragment. The theory behind collagen-fragment peptides is that when collagen naturally breaks down in the skin, the resulting peptide fragments signal to the skin that it should get to work and create some nice, new collagen. [more]
what‑it‑does cell-communicating ingredient
An important compound in our body that has a vital cell-signalling role. It is wound healing, anti-inflammatory and can help with barrier repair. [more]
what‑it‑does exfoliant | chelating
A next generation AHA, a so-called PHA that gently exfoliates skin without irritation. It also moisturizes and helps the skin barrier. It also has antioxidant properties. [more]
what‑it‑does moisturizer/humectant
The big and important protein molecule that usually comes from animal skin such as fish or bovine. The gist of the "collagen in topical skincare" subject is to know that collagen in a jar has nothing to do with wrinkles but everything to do with skin hydration. [more]
what‑it‑does emollient | moisturizer/humectant
The chemically chopped up version of the big protein molecule, collagen. It is often derived from fish or bovine sources and works as a nice moisturizer and humectant that helps the skin to hold onto water.   To understand a bit more what Hydrolyzed Collagen is, you have to know that proteins are large chains of amino acids connected with so-called peptide bonds. [more]
what‑it‑does antimicrobial/antibacterial | preservative
It's an alternative, natural preservative that comes from radishes fermented with Leuconostoc kimchii, a lactic acid bacteria that has been used to make traditional Korean dish, kimchi. [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
It's the salt form of famous humectant and natural moisturizing factor, hyaluronic acid. It can bind huge amounts of water and it's pretty much the current IT-moisturizer. [more]
what‑it‑does antioxidant
A handy multifunctional ingredient that works as a preservative booster, as well as an antioxidant and soothing agent.
what‑it‑does viscosity controlling
irritancy, com. 0, 1
A handy white powder that magically converts a liquid into a nice gel formula. [more]
what‑it‑does viscosity controlling
irritancy, com. 0, 0
A cellulose (the big molecule found in the cell wall of green plants) derivative that is used as an emulsion stabilizer and thickener. 
what‑it‑does buffering
It's a little helper ingredient that helps to set the pH of the products to be right. It has an alkaline pH and can neutralize acidic ingredients.
what‑it‑does moisturizer/humectant
A sugar beet derived amino acid derivative with nice skin protection and moisturization properties. Its special thing is being an osmolyte, a molecule that helps to control cell-water balance.  [more]
what‑it‑does viscosity controlling
A super commonly used thickener and emulsion stabilizer. [more]
what‑it‑does preservative
It can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too. [more]
what‑it‑does antioxidant
what‑it‑does chelating
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. [more]