Night Reset Retinol + Ceramide Sleep Treatment Cream
Ingredients overview
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Dot & Key Night Reset Retinol + Ceramide Sleep Treatment CreamIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
A clear, colorless, low viscosity, volatile (does not absorb into the skin but rather evaporates from it) silicone fluid that has excellent spreadability and leaves a light, silky and smooth feel on the skin.
According to manufacturer info, its big advantage is that it's compatible both with other silicones and with natural plant oils, so it's a great ingredient to formulate products with good-sounding, consumer-pleasing vegetable oils but still maintain a cosmetically elegant, non-greasy and non-tacky feel.
A high-molecular weight silicone elastomer gel (a rubber-like elastic material) that is usually combined with a silicone carrier fluid like Caprylyl Methicone. The blend has a viscous gel texture, gives smooth, powdery, nongreasy skin feel, and great spreadability.
It's also more compatible with natural vegetable oils than other silicone elastomer gels and works as a delivery aid both for oil-loving (e.g. sunscreens) and water-loving (vitamin C, Aloe Vera, Caffeine) materials.
A super commonly used 5 unit long, cyclic structured silicone that is water-thin and does not stay on the skin but evaporates from it (called volatile silicone). Similar to other silicones, it gives skin and hair a silky, smooth feel.
It's often combined with the non-volatile (i.e. stays on the skin) dimethicone as the two together form a water-resistant, breathable protective barrier on the skin without a negative tacky feel.
A high-molecular-weight silicone elastomer (rubber-like elastic material) that is usually blended with a base silicone fluid (such as dimethicone or cyclopentasiloxane) to give the formula a silky smooth feel and to act as a thickening agent.
It's a film-forming and thickening polymer (a large molecule composed of many repeated subunits) that comes to the formula usually as part of an emulsifier, thickener trio (with C13-14 Isoparaffin and Laureth-7, trade named Sepigel 305). This trio is an easy-to-use liquid that helps to create nice, non-tacky gel formulas.
It's a petroleum derived emollient and thickener. It often comes to the formula as part of an emulsifier, thickener trio (with Polyacrylamide and Laureth-7). This trio is an easy-to-use liquid that helps to create nice, non-tacky gel formulas.
A not-very-interesting helper ingredient that is used as an emulsifier and/or surfactant. Comes from a coconut oil derived fatty alcohol, lauryl alcohol.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
- It’s naturally in our skin and behaves there like a sponge
- It can bind up to 1000 times its own weight in water
- It is a big molecule from repeated subunits (polymer) so different molecular weight versions exist (unfortunately there is no way to determine MW from INCI list only)
- High-molecular-weight-HA (>500 kDa) is an excellent surface hydrator, skin protectant and can act as an osmotic pump helping water-soluble actives to penetrate deeper into the skin
- Low-molecular-weight-HA (< 500 kDa) can hydrate the skin somewhat deeper though it is still a big molecule and works mainly in the epidermis (outer layer of the skin)
- Low-molecular-weight-HA might also help the skin to repair itself by increasing its self-defense (~ 200kDa used in the study)
- Ultra-low-molecular-weight-HA (<50kDa) is a controversial ingredient and might work as a pro-inflammatory signal molecule
It’s a little helper ingredient that helps to set the pH of a cosmetic formulation to be just right. It’s very alkaline (you know the opposite of being very acidic): a 1% solution has a pH of around 10.
It does not have the very best safety reputation but in general, you do not have to worry about it.
What is true is that if a product contains so-called N-nitrogenating agents (e.g.: preservatives like 2-Bromo-2-Nitropropane-1,3-Diol, 5-Bromo-5-Nitro- 1,3-Dioxane or sodium nitrate - so look out for things with nitro, nitra in the name) that together with TEA can form some not nice carcinogenic stuff (that is called nitrosamines). But with proper formulation that does not happen, TEA in itself is not a bad guy.
But let’s assume a bad combination of ingredients were used and the nitrosamines formed. :( Even in that case you are probably fine because as far as we know it cannot penetrate the skin.
But to be on the safe side, if you see Triethanolamine in an INCI and also something with nitra, nitro in the name of it just skip the product, that cannot hurt.
Though its long name does not reveal it, this polymer molecule (big molecule from repeated subunits or monomers) is a relative to the super common, water-loving thickener, Carbomer. Both of them are big molecules that contain acrylic acid units, but Acrylates/C10-30 Alkyl Acrylate Crosspolymer also contains some other monomers that are hydrophobic, i.e. water-hating.
This means that our molecule is part water- and part oil-loving, so it not only works as a thickener but also as an emulsion stabilizer. It is very common in gel-type formulas that also contain an oil-phase as well as in cleansers as it also works with most cleansing agents (unlike a lot of other thickeners).
A tripeptide (three amino acids attached to each other: Lys-Val-Lys) that's claimed to protect and boost collagen and improve skin texture.
The manufacturer did an in-vivo (made on real people) study with 45 volunteers and found that used twice daily for 84 days 1% and 2.5% Syn-Coll reduces the appearance of wrinkles by 7 and 12% respectively. In another study (also by the manufacturer) with 33 female Chinese volunteers, 77% of the participants felt that Syn-Coll visibly improved the firmness and elasticity of the skin after 4 weeks. What's more, 60% of the participants also noticed a reduction in the look of the pore size also after 4 weeks of treatment.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
- Retinol (pure Vitamin A) is probably the most proven anti-aging ingredient available OTC
- It has to be converted in the skin to retinoic acid to work its magic
- Once converted, it has the same effect as all-trans-retinoic acid, aka tretinoin
- A generally accepted ballpark number is that retinol is 10-to-20 times less potent than retinoic acid
- It makes skin less wrinkled, smoother, firmer and tighter
- It might also be helpful for acne prone skin as it normalizes keratinization and makes the pores produce less sebum
- Possible side effects and irritation are also much less than with retinoic acid
- Do not use whilst pregnant
One of the many types of ceramides that can be found naturally in the upper layer of the skin. Ceramides make up about 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated. It works even better when combined with its pal, Ceramide 1.
We wrote way more about ceramides at ceramide 1, so click here to know more.
We don't have description for this ingredient yet.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version.
According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E.
It's the acronym for Butylated Hydroxy Toluene. It's a common synthetic antioxidant that's used as a preservative.
There is some controversy around BHT. It's not a new ingredient, it has been used both as a food and cosmetics additive since the 1970s. Plenty of studies tried to examine if it's a carcinogen or not. This Truth in Aging article details the situation and also writes that all these studies examine BHT when taken orally.
As for cosmetics, the CIR (Cosmetic Ingredient Review) concluded that the amount of BHT used in cosmetic products is low (usually around 0.01-0.1%), it does not penetrate skin far enough to be absorbed into the bloodstream and it is safe to use in cosmetics.
We don't have description for this ingredient yet.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
As you may guess, if something is only recommended in products that you rinse off (cleansers and shampoos), then it’s probably not the best ingredient for the skin.
Methylisothiazolinone (MI) is a preservative that' super efficient against bacteria at surprisingly low concentrations. The problem with it though is that it can also sensitize and irritate the skin quite easily when it comes in leave-on formulas.
Currently, some countries are considering to ban it entirely (like Denmark) and the permitted use level is very low (under 0.01%). Luckily there are plenty of products on the market with other preservative options so if you are a better safe than sorry type it's probably best to avoid it.
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
It is typically used in tiny amounts, around 0.1% or less.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!).
If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.
Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!).
We don't have description for this ingredient yet.
The oil coming from the seeds of dog-rose, a wild rose species native to Europe, northwest Africa and western Asia. It's a nice emollient, moisturizing plant oil loaded with skin-nourishing fatty acids (linoleic acid - 51%, linolenic acid - 19% and oleic acid - 20%).
If you start to dig a bit deeper into the rosehip oil topic, you will soon see that there are lots of species of rose, and it's all a bit confusing to know what the differences and similarities between the oils of the different roses are. As far as our research can tell, here is the gist.
In skincare two major types of rosehip oil are used:
1. Rosa Rubiginosa that is a synonym for Rosa Eglanteria and for Rosa Mosqueta. We will call it RR from now on.
2. Rosa Canina, or RC
The oil content and composition of RR and RC is similar, but there are some differences: RR contains 8% of oil, while RC contains a bit more, 10%. However, the quality of RR oil seems to be a bit better: it contains 78% essential unsaturated fatty acids while RC contains only 71%. Also, the linoleic-oleic ratio of RR is better (3.3 vs 2.5) that might be important if your skin is acne-prone (as linoleic acid is good for acne and oleic is not).
There is one more important thing to mention: RR oil is famous for containing the miracle active, tretinoin. Though Wikipedia puts RR and RC oil under the same article called as Rose hip seed oil, the referenced research about tretinoin content examines only Rosa Rubiginosa. We looked for a research paper explicitly stating that Rosa Canina also contains tretinoin, but could not find one, so we can neither deny nor confirm it. What we could find is a paper mentioning the tocopherols (vitamin E) and carotenoids (pro-vitamin A) content of Rosa Canina oil that gives it some nice antioxidant properties.
All in all, it is a great emollient plant oil with great fatty acids beneficial for any skin type.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
We don't have description for this ingredient yet.
Jojoba Oil/Macadamia Seed Oil Esters is the major component of a skin surface lipid mimetic mixture trade named L22.
So what the heck is a skin surface lipid mimetic mixture? Let's start with skin surface lipids (SLSs): these are the oily substances that your skin produces (mainly the sebaceous glands, a smaller part comes from the epidermis) to keep the skin nice and moisturized. The main components are fatty acids (FAs), triglycerides, cholesterol, cholesteryl esters, wax esters, and squalene. This mixture has a super important role in keeping the skin barrier healthy.
So Jojoba Oil/Macadamia Seed Oil Esters is a jojoba and macadamia oil-derived ingredient that contains fatty acids, triglycerides, and wax esters. It comes to the formula with Squalene, Phytosteryl Macadamiate (botanical sourced version of cholesteryl ester) and Phytosterols (botanical version of cholesterol) in the ratios found in young, healthy adult skin.
So the main skill of L22 is barrier repair and skin hydration and the manufacturer did several double-blind, vehicle-controlled studies to show it really works. It compared 3% of L22 with 3% of olive oil or 3% of caprylic/capric triglyceride alone or combined with Ceramide 2 in a vehicle. 60 minutes after the application, barrier recovery was by far the best by the L22 + Ceramide 2 (0.1%) combination, followed by L22 alone, and then by Olive + Ceramide 2 and Olive alone. Skin hydration was measured 4 hours after application and again, the L22 + Ceramide 2 combination performed the best followed by L22 alone.
Another study compared 3% L22 with 3% petrolatum (the gold standard occlusive agent). After 1 hour, they performed similarly both for barrier repair and skin hydration, but after 2 weeks of use and a 1 week regression period, L22 showed significantly better results.
So the bottom line is: if barrier repair is something that you are interested in, the skin surface lipids of L22 can definitely be worth a try. Even better, if the formula also contains Ceramide 2.
Squalene is an oily liquid that originally comes from shark liver but luckily it can also be found in a couple of plant oils. Olive (0.6%), peanut (0.1%) and pumpkin (0.35%) oils contain it, though not in huge amounts.
What contains more of it, is the sebum (the oily stuff) that our skin produces. About 13% of human sebum is squalene, which means that it’s an important skin-identical ingredient and NMF (natural moisturizing factor).
Chemically speaking, it is an unsaturated (has double bonds) hydrocarbon (contains only carbon and hydrogen) molecule, that can undergo oxidation. On the pro side, this means that squalene can act as an antioxidant (while its no-double-bond version sister, squalane cannot), but on the con side, squalene is less stable and has a shorter shelf life.
This is probably the main reason why its no-double bond and hence more stable sister, squalane shows up more often on ingredient lists. Read about squalane here >>
Phytosteryl Macadamiate is the combination of phytosterol and fatty acids coming from Macadamia oil. It is a botanical version of cholesteryl esters found in skin surface lipids. It comes to the ingredient list as part of L22, a skin surface lipid mimetic whose main job is barrier repair and skin hydration.
We don't have description for this ingredient yet.
- Primary fat-soluble antioxidant in our skin
- Significant photoprotection against UVB rays
- Vit C + Vit E work in synergy and provide great photoprotection
- Has emollient properties
- Easy to formulate, stable and relatively inexpensive
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what‑it‑does | solvent |
what‑it‑does | emollient |
what‑it‑does | emollient | solvent |
what‑it‑does | viscosity controlling |
what‑it‑does | viscosity controlling |
what‑it‑does | emollient | viscosity controlling | solvent |
what‑it‑does | emulsifying | surfactant/cleansing |
what‑it‑does | skin-identical ingredient | moisturizer/humectant |
what‑it‑does | buffering |
irritancy, com. | 0, 2 |
what‑it‑does | viscosity controlling |
what‑it‑does | cell-communicating ingredient |
what‑it‑does | skin-identical ingredient | moisturizer/humectant |
irritancy, com. | 0, 0 |
what‑it‑does | cell-communicating ingredient |
what‑it‑does | skin-identical ingredient |
what‑it‑does | skin-identical ingredient | moisturizer/humectant |
irritancy, com. | 0, 0 |
what‑it‑does | antioxidant |
irritancy, com. | 0, 0 |
what‑it‑does | antioxidant | preservative |
what‑it‑does | antimicrobial/antibacterial | preservative |
what‑it‑does | preservative |
what‑it‑does | preservative |
what‑it‑does | chelating |
what‑it‑does | colorant |
irritancy, com. | 2, 2 |
what‑it‑does | antioxidant |
what‑it‑does | perfuming |
what‑it‑does | emollient | perfuming |
what‑it‑does | emollient |
what‑it‑does | soothing |
what‑it‑does | antioxidant |
what‑it‑does | skin-identical ingredient | emollient |
what‑it‑does | skin-identical ingredient | antioxidant | emollient |
what‑it‑does | emollient | skin-identical ingredient |
what‑it‑does | antioxidant |
irritancy, com. | 0-3, 0-3 |