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Bioderma Sébium Global

Bioderma
Sébium Global

Bioderma Sébium Global is an intensive purifying care for acne-prone skin. It allows to eliminate spots and blackheads while restoring the skin's clear aspect.
Uploaded by: hainpilav on 18/07/2019

Skim through

Ingredient name what-it-does irr., com. ID-Rating
Aqua/Water/Eau solvent
C12-13 Alkyl Lactate emollient
Citric Acid exfoliant, buffering goodie
Dipropylene Glycol solvent
Cyclopentasiloxane emollient, solvent
Sodium Hydroxide buffering
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 superstar
Methyl Methacrylate Crosspolymer
Zinc Gluconate anti-acne, soothing goodie
Salicylic Acid exfoliant, anti-acne, soothing, preservative superstar
Arachidyl Alcohol emollient, viscosity controlling
Dimethicone emollient 0, 1
Behenyl Alcohol emollient, viscosity controlling
Glyceryl Stearate emollient, emulsifying 0, 1-2
PEG-100 Stearate surfactant/​cleansing, emulsifying 0, 0
Silica viscosity controlling
Xanthan Gum viscosity controlling
Arachidyl Glucoside emulsifying
C30-45 Alkyl Cetearyl Dimethicone Crosspolymer emollient
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer viscosity controlling
Glycyrrhetinic Acid
Squalane skin-identical ingredient, emollient 0, 1 goodie
Bakuchiol cell-communicating ingredient goodie
Sodium Metabisulfite preservative
Xylitol moisturizer/​humectant goodie
Propylene Glycol moisturizer/​humectant, solvent 0, 0
Polysorbate 60 emulsifying, surfactant/​cleansing
Sorbitan Isostearate emulsifying 0, 1-2
Fructooligosaccharides moisturizer/​humectant
Mannitol moisturizer/​humectant goodie
Propyl Gallate antioxidant, perfuming
Caprylic/Capric Triglyceride emollient
Ginkgo Biloba Leaf Extract
Rhamnose moisturizer/​humectant
Laminaria Ochroleuca Extract
Fragrance (Parfum) perfuming icky

Bioderma Sébium Global
Ingredients explained

Also-called: Aqua;Water | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

What-it-does: emollient

We don't have description for this ingredient yet.

Citric Acid - goodie
What-it-does: exfoliant, buffering

Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA. 

So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh. 

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There is also some research showing that citric acid with regular use (think three months and 20% concentration) can help sun-damaged skin, increase skin thickness and some nice hydrating things called glycosaminoglycans in the skin. 

But according to a comparative study done in 1995, citric acid has less skin improving magic properties than glycolic or lactic acid. Probably that’s why citric acid is usually not used as an exfoliant but more as a helper ingredient in small amounts to adjust the pH of a formulation. 

What-it-does: solvent

A clear, colorless liquid that works as a solvent and viscosity decreasing ingredient. It also has great skin-moisturizing abilities. 

What-it-does: emollient, solvent

A super commonly used 5 unit long, cyclic structured silicone that is water-thin and does not stay on the skin but evaporates from it (called volatile silicone). Similar to other silicones, it gives skin and hair a silky, smooth feel

It's often combined with the non-volatile (i.e. stays on the skin) dimethicone as the two together form a water-resistant, breathable protective barrier on the skin without a negative tacky feel.

Also-called: lye | What-it-does: buffering

The unfancy name for it is lye. It’s a solid white stuff that’s very alkaline and used in small amounts to adjust the pH of the product and make it just right. 

For example, in case of AHA or BHA exfoliants, the right pH is super-duper important, and pH adjusters like sodium hydroxide are needed.  

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BTW, lye is not something new. It was already used by ancient Egyptians to help oil and fat magically turn into something else. Can you guess what? Yes, it’s soap. It still often shows up in the ingredient list of soaps and other cleansers.

Sodium hydroxide in itself is a potent skin irritant, but once it's reacted (as it is usually in skin care products, like exfoliants) it is totally harmless.

Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • A super common, safe, effective and cheap molecule used for more than 50 years
  • Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
  • Effective from as low as 3% with even more benefits at higher concentrations up to 20-40% (around 10% is a good usability-effectiveness sweet spot)
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

What-it-does: absorbent/mattifier

Porous spherical microbeads (tiny little balls) that can give an elegant silky texture to the products. They are also used to scatter light to reduce the look of fine lines on the skin, as well as to absorb excess oil and give a matt finish. 

What-it-does: anti-acne, soothing

If you are fighting acne and have looked into oral supplements, chances are that zinc gluconate sounds familiar to you. It is a zinc salt that has research proving it to be effective against inflammatory acne, though not quite as effective as the antibiotic minocycline (31.2% vs. 63.4% success rate). However, zinc supplements are easily available, have little-to-no side effects, so supplementing them with a 30mg per day dose can still be a good idea.

As for smearing zinc gluconate all over your face, it is also not a bad idea. Zinc has multiple magic abilities: it is antibacterial (including evil, acne-causing P. acnes) and sebum-regulating (5α-reductase inhibitor), great for acne-prone skin types. It also stimulates antioxidant enzyme systems (mainly superoxide dismutase) and has nice wound healing abilities acting mainly in the first, proliferation phase. So great for skin types in need of healing and soothing.

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What about the gluconate part? It is there to promote the absorption and bioavailability of zinc and also plays a role in cellular regeneration (involved in the synthesis of ribose sugars, structural components of DNA and RNA).

Salicylic Acid - superstar
Also-called: BHA | What-it-does: exfoliant, anti-acne, soothing, preservative
  • It's one of the gold standard ingredients for treating problem skin
  • It can exfoliate skin both on the surface and in the pores
  • It's a potent anti-inflammatory agent
  • It's more effective for treating blackheads than acne
  • For acne combine it with antibacterial agents like benzoyl peroxide or azelaic acid
Read all the geeky details about Salicylic Acid here >>

A fatty alcohol (the non-drying type with a long oil loving chain of 20 carbon atoms) that is used to increase the viscosity of the formula and it also helps the oily and the watery parts to stay nicely mixed together (called emulsion stabilizing). 

What-it-does: emollient | Irritancy: 0 | Comedogenicity: 1

Probably the most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.

As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity. 

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As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types). 

A fatty alcohol (the non-drying type with a long oil loving chain of 22 carbon atoms) that is used to increase the viscosity of the formula and it also helps the oily and the watery parts to stay nicely mixed together (called emulsion stabilizing). 

What-it-does: emollient, emulsifying | Irritancy: 0 | Comedogenicity: 1-2

A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.

Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.

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It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".

What-it-does: surfactant/cleansing, emulsifying | Irritancy: 0 | Comedogenicity: 0

A very common water-loving surfactant and emulsifier that helps to keep water and oil mixed nicely together. 

It's often paired with glyceryl stearate - the two together form a super effective emulsifier duo that's salt and acid tolerant and works over a wide pH range. It also gives a "pleasing product aesthetics", so no wonder it's popular.

A white powdery thing that's the major component of glass and sand. In cosmetics, it’s often in products that are supposed to keep your skin matte as it has great oil-absorbing abilities. It’s also used as a helper ingredient to thicken up products or suspend insoluble particles. 

It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little of xanthan gum will make it more gel-like.  Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). 

Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415). 

What-it-does: emulsifying

An ingredient that is created from the attachment of the water-loving sugar molecule, glucose, and an oil-loving 20 carbon long fatty chain. This makes it a partly water- and partly oil-soluble material, meaning it functions as an emulsifier helping oil and water to mix.  

Most often, it comes to the formula coupled with two fatty alcohol friends, Arachidyl and Behenyl alcohol, to make up an emulsifier trio trade named Montanov 202. As described by its manufacturer, the main thing of Montanonv 202 is that it gives creams a unique evanescent and light feel with a matt finish. It also leaves the skin soft, but not oily, is hypoallergenic and non-comedogenic making it perfect for both oily and sensitive skin formulas. 

What-it-does: emollient

We don't have description for this ingredient yet.

Also-called: Sepinov EMT 10 | What-it-does: viscosity controlling, emulsion stabilising

This long-named, polymer molecule (big molecule from repeated subunits) is a helper ingredient that's good at emulsifying and stabilizing oils into water-based formulas. It also acts as a thickening and gelling agent that creates nice, non-sticky and supple textures. It works over a very wide pH range (3-12) and can be used to thicken up low-ph formulas, such as exfoliants.

We don't have description for this ingredient yet.

Squalane - goodie
What-it-does: skin-identical ingredient, emollient | Irritancy: 0 | Comedogenicity: 1

It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated  (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life. 

It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are "emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, without being heavy or greasy.

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Another advantage of squalane is that it is pretty much compatible with all skin types and skin conditions. It is excellent for acne-prone skin and safe to use even if you have fungi-related skin issues, like seborrhea or fungal acne.

The unsaturated (with double bonds) and hence less stable version of Squalane is Squalene, you can read about it here >> 

Bakuchiol - goodie
Also-called: Sytenol A, Phyto Retinol | What-it-does: cell-communicating ingredient

At first glance, you could think that Bakuchiol is your average plant extract. It is derived from the seeds of Psoralea Corylifolia, aka Babchi, a plant important in Indian and Chinese medicine. The molecule was first isolated in 1973 and several anti-something properties are known about it: it has anti-inflammatory, antioxidant, anti-tumor, anti-bacterial and hepatoprotective magical abilities like plenty of other Ayurvedic plant extracts.

What makes Bakuchiol a special snowflake is the recent discovery that it behaves on the skin in a way very similar to well-known skincare superstar, retinol. While chemically, it has nothing to do with the vitamin-A family, aka retinoids, comparative gene expression profiling (a fancy way of saying that they compared how retinol and bakuchiol modify the way  skin cells behave and produce important skin proteins such as collagen) shows that retinol and bakuchiol regulate skin cell behavior in a similar way. 

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To be more specific, both Bakuchiol and retinol upregulate collagen I, III and IV production and downregulate MMP, the evil collagen attacking enzyme in our skin. This means more collagen stays in our skin and we all know that more collagen equals firmer, more wrinkle-free skin.  A 12-week clinical study using a 0.5% Bakuchiol formula with 17 people using it twice a day confirmed a significant improvement in lines and wrinkles, elasticity, firmness and an overall reduction in photo-damage. Also, the test formula was very well tolerated, without any retinol-like side effects. 

What's more, a 2018 double-blind study with 44 people compared 0.5% Bakuchiol with 0.5% retinol cream and found that "bakuchiol is comparable to retinol in its ability to improve photoaging and is better tolerated than retinol". A super promising result after 12 weeks. 

If you are not a daredevil-type who doesn't want to stop using a super well-proven retinol for a newbie like Bakuchiol, we have good news. The two also work very nicely together and Bakuchiol can actually help to stabilize the otherwise unstable and hard to formulate retinol.

And we are still not done, as Bakuchiol shows not only anti-aging properties but also nice anti-acne effects. 1% Bakuchiol seems to be very effective in itself (57% reduction in acne after 6 weeks treatment) and even better when combined with 2% salicylic acid (67% reduction in acne after 6 weeks). We like that Bakuchiol is such a good team player!  The molecule works against acne in multiple ways: It downregulates 5α-reductase (a sebum-controlling enzyme), it is antibacterial (including P. acnes), anti-inflammatory and it inhibits lipid-peroxidation, an evil oxidative process that is recently thought to be a very early trigger in the acne process. 

We feel that this description is becoming very long so we will just mention that Bakuchiol also seems to positively regulate hydration-related genes such as Aquaporin 3 and also shows some melanin-inhibiting properties

Overall, we think Bakuchiol is an awesome molecule with lots of promise both for anti-aging and anti-acne. But the proof compared to the well-established superstars is far from solid, so in a skincare routine, we would rather add Bakuchiol next to retinol than straight up replace it. Unless you are a gimme-the-newest-shiny-thing-under-the-sun-type. 

What-it-does: preservative

We don't have description for this ingredient yet.

Xylitol - goodie
What-it-does: moisturizer/humectant

A type of sugar that's part of a moisturizing trio called Aquaxyl. You can read more about its magic properties at xylitylglucoside

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 0
  • It's a helper ingredient that improves the freeze-thaw stability of products
  • It's also a solvent, humectant and to some extent a penetration enhancer
  • It has a bad reputation among natural cosmetics advocates but cosmetic scientists and toxicology experts do not agree (read more in the geeky details section)
Read all the geeky details about Propylene Glycol here >>

A common little helper ingredient that helps water and oil to mix together, aka emulsifier.

What-it-does: emulsifying | Irritancy: 0 | Comedogenicity: 1-2

A handy helper ingredient that helps water and oil to mix nicely together, aka emulsifier. It is especially recommended for protective, baby care and general purpose emollient creams. 

It also helps to disperse insoluble particles (think color pigments or zinc/titanium dioxide sunscreen) nice and even in cosmetic formulas. 

What-it-does: moisturizer/humectant

We don't have description for this ingredient yet.

Mannitol - goodie
What-it-does: moisturizer/humectant

A type of sugar molecule, that has water-binding properties and helps to keep your skin hydrated

What-it-does: antioxidant, perfuming

We don't have description for this ingredient yet.

What-it-does: emollient

A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, and it’s also easy to formulate with. No wonder it’s popular. 

Also-called: Ginkgo Biloba Extract

We don't have description for this ingredient yet.

What-it-does: moisturizer/humectant

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Also-called: Fragrance, Parfum;Parfum/Fragrance | What-it-does: perfuming

Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!). 

If you are someone who likes to know what you put on your face than fragrance is not your best friend - no way to know what’s really in it.  

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Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!). 

You may also want to take a look at...

what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
what‑it‑does emollient
what‑it‑does exfoliant | buffering
An AHA that comes from citrus fruits. It is usually used as a helper ingredient to adjust the pH of the formula. [more]
what‑it‑does solvent
A clear, colorless liquid that works as a solvent and viscosity decreasing ingredient. It also has great skin-moisturizing abilities.  [more]
what‑it‑does emollient | solvent
It's a super commonly used water-thin volatile silicone that gives skin and hair a silky, smooth feel.  [more]
what‑it‑does buffering
Lye - A solid white stuff that’s very alkaline and used in small amount to adjust the pH of the product.  [more]
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0, 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
Porous spherical microbeads that can give an elegant silky texture to the products. They are also used to scatter light to reduce the look of fine lines on the skin, as well as to absorb excess oil and give a matt finish. 
what‑it‑does anti-acne | soothing
A zinc salt known for its soothing and wound healing properties as well as for its anti-acne properties.  [more]
what‑it‑does exfoliant | anti-acne | soothing | preservative
One of the gold standard ingredients for treating problem skin. It can exfoliate skin both on the surface and in the pores (pH 3-4 needed) and it's a potent anti-inflammatory agent. [more]
what‑it‑does emollient | viscosity controlling
A fatty alcohol (the non-drying type with a long oil loving chain of 20 carbon atoms) that is used to increase the viscosity of the formula and it also helps the oily and the watery parts to stay nicely mixed together (called emulsion stabilizing).  [more]
what‑it‑does emollient
irritancy, com. 0, 1
A very common silicone that gives both skin and hair a silky smooth feel. It also forms a protective barrier on the skin and fills in fine lines. Also used for scar treatment. [more]
what‑it‑does emollient | viscosity controlling
A fatty alcohol (the non-drying type) that is used to increase the viscosity of the formula and stabilize emulsions. [more]
what‑it‑does emollient | emulsifying
irritancy, com. 0, 1-2
Waxy, white, solid stuff that helps water and oil to mix together and leaves the skin feeling soft and smooth. [more]
what‑it‑does surfactant/cleansing | emulsifying
irritancy, com. 0, 0
A commonly used water-soluble surfactant and emulsifier. [more]
what‑it‑does viscosity controlling
A white powdery thing that can mattify the skin and thicken up cosmetic products. [more]
what‑it‑does viscosity controlling
A super commonly used thickener and emulsion stabilizer. [more]
what‑it‑does emulsifying
An ingredient that is created from the attachment of the water-loving sugar molecule, glucose, and an oil-loving 20 carbon long fatty chain. This makes it a partly water- and partly oil-soluble material, meaning it functions as an emulsifier helping oil and water to mix.   Most often, it comes to the formula coupled with two fatty alcohol friends, Arachidyl and Behenyl alcohol, to make [more]
what‑it‑does emollient
what‑it‑does viscosity controlling
A helper ingredient that's good at stabilizing water-based formulas and also serves as a thickener. [more]
what‑it‑does skin-identical ingredient | emollient
irritancy, com. 0, 1
An emollient and natural moisturizer that can be found also in the sebum (oily stuff our skin produces). It leaves a nice non-greasy, non-heavy feeling on the skin. [more]
what‑it‑does cell-communicating ingredient
At first glance, you could think that Bakuchiol is your average plant extract. It is derived from the seeds of Psoralea Corylifolia, aka Babchi, a plant important in Indian and Chinese medicine. [more]
what‑it‑does preservative
what‑it‑does moisturizer/humectant
A type of sugar that's part of a moisturizing trio called Aquaxyl. You can read more about its magic properties at xylitylglucoside.  [more]
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0, 0
A common glycol that improves the freeze-thaw stability of products. It's also a solvent, humectant and to some extent a penetration enhancer. [more]
what‑it‑does emulsifying | surfactant/cleansing
A common little helper ingredient that helps water and oil to mix together, aka emulsifier.
what‑it‑does emulsifying
irritancy, com. 0, 1-2
A handy helper ingredient that helps water and oil to mix nicely together. [more]
what‑it‑does moisturizer/humectant
what‑it‑does moisturizer/humectant
A type of sugar molecule, that has water-binding properties and helps to keep your skin hydrated.  [more]
what‑it‑does antioxidant | perfuming
what‑it‑does emollient
A very common emollient that makes your skin feel nice and smooth. Comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. [more]
what‑it‑does moisturizer/humectant
what‑it‑does perfuming
The generic term for nice smelling stuff put into cosmetic products so that the end product also smells nice. It is made up of 30 to 50 chemicals on average. [more]