P.Calm

Retinolagen Ampoule Shot Cream

A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives. 

A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular. 

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

• It’s a polyhydroxy acid (PHA), that is often referred to as next generation AHA
• It gently lifts off dead skin cells form the skin surface making skin smooth and even
• In the long term it provides anti-aging benefits, like increased skin thickness and decreased wrinkles (though a tad less than even more proven superstar AHAs)
• It’s a great moisturizer and even helps to repair impaired skin barrier
• It’s antioxidant, and does not make your skin more sensitive to the sun
• It can be used even if your skin is very sensitive, rosacea prone or if you are post cosmetic procedure

At first glance, you could think that Bakuchiol is your average plant extract. It is derived from the seeds of Psoralea Corylifolia, aka Babchi, a plant important in Indian and Chinese medicine. The molecule was first isolated in 1973 and several anti-something properties are known about it: it has anti-inflammatory, antioxidant, anti-tumor, anti-bacterial and hepatoprotective magical abilities like plenty of other Ayurvedic plant extracts.

What makes Bakuchiol a special snowflake is the recent discovery that it behaves on the skin in a way very similar to well-known skincare superstar, retinol. While chemically, it has nothing to do with the vitamin-A family, aka retinoids, comparative gene expression profiling (a fancy way of saying that they compared how retinol and bakuchiol modify the way  skin cells behave and produce important skin proteins such as collagen) shows that retinol and bakuchiol regulate skin cell behavior in a similar way. 

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If you are reading here, we are pretty sure the words retinoids and retinol ring a bell, but if not, you are seriously missing out, please click here immediately to catch up.  The TL;DR version is that retinoids are the royal family of skincare with tretinoin being the king, the only FDA-approved ingredient to treat the signs of photoaging. Retinol is like a grandkid, it has to be converted (through two steps) in the skin to become retinoic acid. The conversion means retinol is both less effective and less harsh on the skin. 

So where does our current molecule, Retinal, aka Retinaldehyde fit into the family (btw, here is a nice visual family tree about who is who)?  Remember that retinol needed two conversion steps to become retinoic acid? Yes, you are right, Retinal is the intermediate step between retinoic acid and retinol, meaning it needs only one conversion step to become active in the skin. If we go with our royal family analogy, Retinal is Prince William, directly next in line to the throne. 

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• Works best between a concentration of 5-20%
• Boosts the skin’s own collagen production
• Fades pigmentation and brown spots
• If used under sunscreen it boosts its UV protection
• Extremely unstable and oxidizes very easily in presence of light or air
• Stable in solutions with water only if pH is less than 3.5 or in waterless formulations
• Vit E + C work in synergy and provide superb photoprotection
• Ferulic acid doubles the photoprotection effect of Vit C+E and helps to stabilize Vit C
• Potent Vit. C serums might cause a slight tingling on sensitive skin

We don't have description for this ingredient yet.

A sugar beet-derived amino acid derivative with nice skin protection and moisturization properties. Betaine's special thing is being an osmolyte, a molecule that helps to control cell-water balance.  It is also a natural osmoprotectant, meaning that it attracts water away from the protein surface and thus protects them from denaturation and increases their thermodynamic stability. 

It also gives sensorial benefits to the formula and when used in cleansers, it helps to make them milder and gentler. 

An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid). 

Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier. 

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• Retinol (pure Vitamin A) is probably the most proven anti-aging ingredient available OTC
• It has to be converted in the skin to retinoic acid to work its magic
• Once converted, it has the same effect as all-trans-retinoic acid, aka tretinoin
• A generally accepted ballpark number is that retinol is 10-to-20 times less potent than retinoic acid
• It makes skin less wrinkled, smoother, firmer and tighter
• It might also be helpful for acne prone skin as it normalizes keratinization and makes the pores produce less sebum
• Possible side effects and irritation are also much less than with retinoic acid
• Do not use whilst pregnant

Super common soothing ingredient. It can be found naturally in the roots & leaves of the comfrey plant, but more often than not what's in the cosmetic products is produced synthetically. 

It's not only soothing but it' also skin-softening and protecting and can promote wound healing.

Adenosine is an important little compound in our body that has a vital cell-signalling role. Research on smearing it on our face is also promising and shows so far a couple of things:

• It can help with wound healing
• It’s a good anti-inflammatory agent
• It might even help with skin’s own collagen production and improve skin firmness and elasticity
• It helps with barrier repair and protection
• It might be even useful for the hair helping with hair thickness and hair growth

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Turmeric is the yellow spice you probably know from curry and Indian food. It's also a traditional herbal medicine used in Ayurveda for its bunch of anti-something magic abilities including being anti-inflammatory, antimicrobial, antioxidant and anticarcinogenic. 

As for turmeric and skincare, we have good news: studies show that the root extract and its main biologically active component, curcumin can do multiple good things for the skin. Thanks to its anti-inflammatory and antimicrobial activity, it shows some promise for acne-prone skin and a small study from 2013 showed that it might be able to regulate sebum production. 

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We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

We don't have description for this ingredient yet.

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

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A very common ingredient that can be found in all cell membranes. In cosmetics it's quite the multi-tasker: it's an emollient and water-binding ingredient but it's also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes. 

A copolymer is a big molecule that consists not of one but of two repeating subunits. This particular copolymer is a handy helper ingredient to form nice gel textures.

It usually comes to the formula combined with emollients (such as  C13-14 Isoparaffin, Isohexadecane, Isononyl Isononanoate or Squalane) and can be used as an emulsifier and/or thickener to produce milky gel emulsions with a soft and non-tacky skin feel. 

An ester that comes from Cetearyl alcohol and the fatty acids of olive oil. It often comes to the formula coupled with Sorbitan Olivate as the two together form the well-known, natural emulsifier trade named Olivem 1000. 

Other than helping oil and water to blend, the main thing of Olivem 1000 is generating liquid crystal structures that are similar to the lipid structures of the stratum corneum (the outermost layer of the skin). Thanks to this, Olivem 1000 doubles as an active ingredient with significant moisturizing, barrier-repairing and soothing properties.

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A polymer (big molecule from repeated subunits) that's used as a gloss improver for lipsticks and lipglosses. Its stickiness also helps lip products to stay on longer. 

Combined with polyacrylate-13 and polysorbate 20, it forms a very effective tickener-emulsifier trio.

An ester coming from sorbitol and the fatty acids of olive oil. It is part of the popular emulsifier trade named Olivem 1000 that is well-known for generating biomimetic liquid crystal structures. We have more info on Olivem 1000 at Cetearyl Olivate >>

A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula.  It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.

A semi-essential (infants cannot synthesize it, but adults can) amino acid that is one of the primary building blocks of hair keratin and skin collagen. It's a natural moisturizing factor, a skin hydrator and might also help to speed up wound healing. 

Arginine usually has a positive charge (cationic) that makes it substantive to skin and hair (those are more negatively charged surfaces) and an excellent film former.  Thanks to the positive charge, it also creates a complex with AHAs (AHAs like to lose a hydrogen ion and be negatively charged, so the positive and the negative ions attract each other) that causes a "time-release AHA effect" and reduces the irritation associated with AHAs. 

Glyceryl acrylate/acrylic acid copolymer is the fancy word for a common polymer (big molecule from repeated subunits), namely polyacrylic acid (aka carbomer when it comes to cosmetics) with glycerin attached to it in some places.

The main thing of this polymer is that it forms a hydrogel (trade named Lubrajel) that can sit on top of the skin and provide moisturizing, water-soluble ingredients such as glycerin to the skin. Think of it as a very thin, wet sponge that a cosmetic manufacturer can fill with good ingredients for your skin. It also works as a thickening agent (remember, it is a carbomer type of molecule), and can provide the skin with a nice slippery feel. It can also draw water to the skin (thank you, pendant glycerol groups!), providing skin hydration.

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We don't have description for this ingredient yet.

A mainly oil-loving, vegetable raw material based ingredient that helps water and oil to mix together, aka emulsifier. It can also function as a wetting and dispersing agent helping insoluble particles such as color pigments or inorganic sunscreens (zinc/titanium dioxide) to disperse nice and even in liquids.  

Chemically speaking, it comes from the attachment of sorbitan (a dehydrated sorbitol (sugar) molecule) with the unsaturated fatty acid Oleic Acid, that creates a partly water (the sorbitan part) and partly oil soluble (oleic part) molecule. 

A superabsorbent polymer (big molecule from repeated subunits) that has crazy water binding abilities. Sometimes its referred to as "waterlock" and can absorb 100 to 1000 times its mass in water. 

As for its use in cosmetic products, it is a handy multi-tasker that thickens up water-based formulas and also has some emulsifying and emulsion stabilizing properties. 

Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.

It is typically used in tiny amounts, around 0.1% or less.

It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 

It's the acronym for Butylated Hydroxy Toluene. It's a common synthetic antioxidant that's used as a preservative.

There is some controversy around BHT. It's not a new ingredient, it has been used both as a food and cosmetics additive since the 1970s. Plenty of studies tried to examine if it's a carcinogen or not. This Truth in Aging article details the situation and also writes that all these studies examine BHT when taken orally.

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It's the acronym for Butylated Hydroxy Anisole. It's a synthetic antioxidant that's used as a preservative. 

It's a somewhat controversial ingredient: The U.S. National Institutes of Health says that BHA is "reasonably anticipated to be a human carcinogen based on evidence of carcinogenicity in experimental animals" (source: wikipedia). But, and this is a big but: these experiments were made on animals and BHA was used in high doses as part of their diet. There is no evidence that the same is true when used in tiny amounts in cosmetics products. So you probably have nothing to worry about, but if you are a better safe than sorry type there are plenty of nice products without BHA to choose from. :)