No7 Protect And Perfect Serum
No7

Protect And Perfect Serum

Clinically proven to be even more effective at reducing the appearance of fine lines.
Uploaded by: angie5070 on 03/01/2018

Ingredients overview

Dimethicone
what‑it‑does emollient
irritancy, com. 0 1
A very common silicone that gives both skin and hair a silky smooth feel. It also forms a protective barrier on the skin and fills in fine lines. Also used for scar treatment. [more]
,
Aqua (Water)
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
,
Dimethicone Crosspolymer
what‑it‑does viscosity controlling
A high-molecular-weight silicone elastomer (rubber-like elastic material) that is usually blended with a base silicone fluid (such as dimethicone or cyclopentasiloxane) to give the formula a silky smooth feel and to act as a thickening agent. [more]
,
Butylene Glycol
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
,
Glycerin
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
,
Alcohol Denat.
what‑it‑does antimicrobial/antibacterial | solvent | viscosity controlling
Alcohol with some additives to make it unconsumable. It is great solvent, penetration enhancer, creates cosmetically elegant, light formulas, great astringent, and antimicrobial. In large amounts, it can be very drying to the skin. [more]
,
Sodium Ascorbyl Phosphate
what‑it‑does antioxidant | anti-acne
The sodium salt form of skincare superstar, vitamin C. If you do not know what the big fuss about vitamin C is, you are missing out and you have to click here and read all the geeky details about it.Pure vitamin C (aka ascorbic acid, AA) is great and all, but its lack of stability is a big challenge for the cosmetics industry. [more]
,
Peg/Ppg-18/18 Dimethicone
what‑it‑does emulsifying
A silicone emulsifier that helps to create water in silicone emulsions. 
,
Magnesium Sulfate
what‑it‑does viscosity controlling
A helper ingredient that is used as a bulking and viscosity controlling agent. It can also be used as a heat generating agent in water-less formulas as it has an instant heat-generating chemical reaction with water.  [more]
, [more]
Phenoxyethanol
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
,
Cetyl Peg/Ppg-10/1 Dimethicone
what‑it‑does emulsifying | surfactant/cleansing
A silicone emulsifier that helps water and silicone oils to mix nicely together. 
,
Polyglyceryl-4 Isostearate
what‑it‑does emulsifying
,
Hexyl Laurate
what‑it‑does emollient
A fast spreading emollient ester (hexyl alcohol + lauric acid) that's used in water in oil emulsions or in water-free formulas. It gives a light skin feel. 
,
Retinyl Palmitate
what‑it‑does cell-communicating ingredient
An ester form of vitamin A (retinol + palmitic acid) that is pretty much the least effective member of the retinoid family. Its anti-aging effects are quite questionable as well as its behavior in the presence of UVA light. (Use it at night if possible!) [more]
,
Hydrolyzed Rice Protein, Propylene Glycol
what‑it‑does moisturizer/humectant | solvent | viscosity controlling
irritancy, com. 0 0
A common glycol that improves the freeze-thaw stability of products. It's also a solvent, humectant and to some extent a penetration enhancer. [more]
,
Tocopheryl Acetate
what‑it‑does antioxidant
irritancy, com. 0 0
A form of vitamin E that works as an antioxidant. Compared to the pure form it's more stable, has longer shelf life, but it's also more poorly absorbed by the skin. [more]
,
Sorbitan Laurate
what‑it‑does emulsifying
,
Salicylic Acid
what‑it‑does exfoliant | anti-acne | soothing | preservative
One of the gold standard ingredients for treating problem skin. It can exfoliate skin both on the surface and in the pores (pH 3-4 needed) and it's a potent anti-inflammatory agent. [more]
,
Methylparaben
what‑it‑does preservative
The most common type of feared-by-everyone-mostly-without-scientific-reason parabens. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon. Apart from the general controversy around parabens (we wrote about it more here), there is a 2006 in-vitro (made in the lab not on real people) research about methylparaben (MP) showing [more]
,
Ethylparaben
what‑it‑does preservative
A very common type of feared-by-everyone-mostly-without-scientific-reason paraben. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon. [more]
,
Carbomer
what‑it‑does viscosity controlling
It’s a handy white powder that magically converts a liquid into a nice gel formula. [more]
,
Medicago Sativa (Alfalfa) Extract, Polysorbate 20
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0 0
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 
,
Hydroxyethylcellulose
what‑it‑does viscosity controlling
A helper ingredient that can thicken up cosmetic products and create beautiful gel formulas. It's derived from cellulose, the major component of the cell wall of green plants. 
,
Panax Ginseng Root Extract
what‑it‑does antioxidant | emollient
Ginseng - A traditional Korean medicine that has antioxidant properties, and is known to improve blood circulation. [more]
,
Morus Alba Leaf Extract, Sodium Benzoate
what‑it‑does preservative
A preservative that works mainly against fungi. Has to be combined with other preservatives. [more]
,
Acetyl Dipeptide-1 Cetyl Ester
what‑it‑does cell-communicating ingredient | soothing
 A soothing dipeptide (tyrosine + arginine) based molecule that functions as a "messenger of tranquility and muscle relaxation". It works via stimulating the skin nerve cells to release met-enkephalin, which is an opioid (i.e. relaxing, pain-relieving) messenger molecule. This means that Acetyl Dipeptide-1 Cetyl Ester can " [more]
,
Tocopherol
what‑it‑does antioxidant
irritancy, com. 2 2
Pure Vitamin E. Great antioxidant that gives significant photoprotection against UVB rays. Works in synergy with Vitamin C. [more]
,
Ethylhexylglycerin
what‑it‑does preservative
It can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too. [more]
,
Palmitoyl Tripeptide-1
what‑it‑does cell-communicating ingredient
A three amino acid peptide that is part of famous peptide duo, Matrixyl 3000. It's a type I collagen fragment that might be able to trick the skin to think that collagen broke down and it's time to create some new one. [more]
,
Palmitoyl Tetrapeptide-7
what‑it‑does cell-communicating ingredient
The pal of Palmitoyl Tripeptide-1 in Matrixyl 3000. A four amino acid peptide that works by reducing the production of the signal molecule, inteleukin-6 (IL-6) that promotes inflammation in the skin. [more]
[less]

Highlights

Key Ingredients

Anti-acne: Sodium Ascorbyl Phosphate
what‑it‑does antioxidant | anti-acne
The sodium salt form of skincare superstar, vitamin C. If you do not know what the big fuss about vitamin C is, you are missing out and you have to click here and read all the geeky details about it.Pure vitamin C (aka ascorbic acid, AA) is great and all, but its lack of stability is a big challenge for the cosmetics industry. [more]
,
Salicylic Acid
what‑it‑does exfoliant | anti-acne | soothing | preservative
One of the gold standard ingredients for treating problem skin. It can exfoliate skin both on the surface and in the pores (pH 3-4 needed) and it's a potent anti-inflammatory agent. [more]
Antioxidant: Sodium Ascorbyl Phosphate
what‑it‑does antioxidant | anti-acne
The sodium salt form of skincare superstar, vitamin C. If you do not know what the big fuss about vitamin C is, you are missing out and you have to click here and read all the geeky details about it.Pure vitamin C (aka ascorbic acid, AA) is great and all, but its lack of stability is a big challenge for the cosmetics industry. [more]
,
Tocopheryl Acetate
what‑it‑does antioxidant
irritancy, com. 0 0
A form of vitamin E that works as an antioxidant. Compared to the pure form it's more stable, has longer shelf life, but it's also more poorly absorbed by the skin. [more]
,
Panax Ginseng Root Extract
what‑it‑does antioxidant | emollient
Ginseng - A traditional Korean medicine that has antioxidant properties, and is known to improve blood circulation. [more]
,
Tocopherol
what‑it‑does antioxidant
irritancy, com. 2 2
Pure Vitamin E. Great antioxidant that gives significant photoprotection against UVB rays. Works in synergy with Vitamin C. [more]
Cell-communicating ingredient: Retinyl Palmitate
what‑it‑does cell-communicating ingredient
An ester form of vitamin A (retinol + palmitic acid) that is pretty much the least effective member of the retinoid family. Its anti-aging effects are quite questionable as well as its behavior in the presence of UVA light. (Use it at night if possible!) [more]
,
Acetyl Dipeptide-1 Cetyl Ester
what‑it‑does cell-communicating ingredient | soothing
 A soothing dipeptide (tyrosine + arginine) based molecule that functions as a "messenger of tranquility and muscle relaxation". It works via stimulating the skin nerve cells to release met-enkephalin, which is an opioid (i.e. relaxing, pain-relieving) messenger molecule. This means that Acetyl Dipeptide-1 Cetyl Ester can " [more]
,
Palmitoyl Tripeptide-1
what‑it‑does cell-communicating ingredient
A three amino acid peptide that is part of famous peptide duo, Matrixyl 3000. It's a type I collagen fragment that might be able to trick the skin to think that collagen broke down and it's time to create some new one. [more]
,
Palmitoyl Tetrapeptide-7
what‑it‑does cell-communicating ingredient
The pal of Palmitoyl Tripeptide-1 in Matrixyl 3000. A four amino acid peptide that works by reducing the production of the signal molecule, inteleukin-6 (IL-6) that promotes inflammation in the skin. [more]
Exfoliant: Salicylic Acid
what‑it‑does exfoliant | anti-acne | soothing | preservative
One of the gold standard ingredients for treating problem skin. It can exfoliate skin both on the surface and in the pores (pH 3-4 needed) and it's a potent anti-inflammatory agent. [more]
Skin-identical ingredient: Glycerin
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
Soothing: Salicylic Acid
what‑it‑does exfoliant | anti-acne | soothing | preservative
One of the gold standard ingredients for treating problem skin. It can exfoliate skin both on the surface and in the pores (pH 3-4 needed) and it's a potent anti-inflammatory agent. [more]
,
Acetyl Dipeptide-1 Cetyl Ester
what‑it‑does cell-communicating ingredient | soothing
 A soothing dipeptide (tyrosine + arginine) based molecule that functions as a "messenger of tranquility and muscle relaxation". It works via stimulating the skin nerve cells to release met-enkephalin, which is an opioid (i.e. relaxing, pain-relieving) messenger molecule. This means that Acetyl Dipeptide-1 Cetyl Ester can " [more]

Show all ingredients by function

Other Ingredients

Antimicrobial/antibacterial: Alcohol Denat.
what‑it‑does antimicrobial/antibacterial | solvent | viscosity controlling
Alcohol with some additives to make it unconsumable. It is great solvent, penetration enhancer, creates cosmetically elegant, light formulas, great astringent, and antimicrobial. In large amounts, it can be very drying to the skin. [more]
Emollient: Dimethicone
what‑it‑does emollient
irritancy, com. 0 1
A very common silicone that gives both skin and hair a silky smooth feel. It also forms a protective barrier on the skin and fills in fine lines. Also used for scar treatment. [more]
,
Hexyl Laurate
what‑it‑does emollient
A fast spreading emollient ester (hexyl alcohol + lauric acid) that's used in water in oil emulsions or in water-free formulas. It gives a light skin feel. 
,
Panax Ginseng Root Extract
what‑it‑does antioxidant | emollient
Ginseng - A traditional Korean medicine that has antioxidant properties, and is known to improve blood circulation. [more]
Emulsifying: Peg/Ppg-18/18 Dimethicone
what‑it‑does emulsifying
A silicone emulsifier that helps to create water in silicone emulsions. 
,
Cetyl Peg/Ppg-10/1 Dimethicone
what‑it‑does emulsifying | surfactant/cleansing
A silicone emulsifier that helps water and silicone oils to mix nicely together. 
,
Polyglyceryl-4 Isostearate
what‑it‑does emulsifying
,
Sorbitan Laurate
what‑it‑does emulsifying
,
Polysorbate 20
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0 0
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 
Moisturizer/humectant: Butylene Glycol
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
,
Glycerin
what‑it‑does skin-identical ingredient | moisturizer/humectant
irritancy, com. 0 0
A real oldie but a goodie. Great natural moisturizer and skin-identical ingredient that plays an important role in skin hydration and general skin health. [more]
,
Propylene Glycol
what‑it‑does moisturizer/humectant | solvent | viscosity controlling
irritancy, com. 0 0
A common glycol that improves the freeze-thaw stability of products. It's also a solvent, humectant and to some extent a penetration enhancer. [more]
Preservative: Phenoxyethanol
what‑it‑does preservative
Pretty much the current IT-preservative. It’s safe and gentle, and can be used up to 1% worldwide. [more]
,
Salicylic Acid
what‑it‑does exfoliant | anti-acne | soothing | preservative
One of the gold standard ingredients for treating problem skin. It can exfoliate skin both on the surface and in the pores (pH 3-4 needed) and it's a potent anti-inflammatory agent. [more]
,
Methylparaben
what‑it‑does preservative
The most common type of feared-by-everyone-mostly-without-scientific-reason parabens. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon. Apart from the general controversy around parabens (we wrote about it more here), there is a 2006 in-vitro (made in the lab not on real people) research about methylparaben (MP) showing [more]
,
Ethylparaben
what‑it‑does preservative
A very common type of feared-by-everyone-mostly-without-scientific-reason paraben. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon. [more]
,
Sodium Benzoate
what‑it‑does preservative
A preservative that works mainly against fungi. Has to be combined with other preservatives. [more]
,
Ethylhexylglycerin
what‑it‑does preservative
It can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too. [more]
Solvent: Aqua (Water)
what‑it‑does solvent
Normal (well kind of - it's purified and deionized) water. Usually the main solvent in cosmetic products. [more]
,
Butylene Glycol
what‑it‑does moisturizer/humectant | solvent
irritancy, com. 0 1
An often used glycol that works as a solvent, humectant, penetration enhancer and also gives a good slip to the products. [more]
,
Alcohol Denat.
what‑it‑does antimicrobial/antibacterial | solvent | viscosity controlling
Alcohol with some additives to make it unconsumable. It is great solvent, penetration enhancer, creates cosmetically elegant, light formulas, great astringent, and antimicrobial. In large amounts, it can be very drying to the skin. [more]
,
Propylene Glycol
what‑it‑does moisturizer/humectant | solvent | viscosity controlling
irritancy, com. 0 0
A common glycol that improves the freeze-thaw stability of products. It's also a solvent, humectant and to some extent a penetration enhancer. [more]
Surfactant/cleansing: Cetyl Peg/Ppg-10/1 Dimethicone
what‑it‑does emulsifying | surfactant/cleansing
A silicone emulsifier that helps water and silicone oils to mix nicely together. 
,
Polysorbate 20
what‑it‑does emulsifying | surfactant/cleansing
irritancy, com. 0 0
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 
Viscosity controlling: Dimethicone Crosspolymer
what‑it‑does viscosity controlling
A high-molecular-weight silicone elastomer (rubber-like elastic material) that is usually blended with a base silicone fluid (such as dimethicone or cyclopentasiloxane) to give the formula a silky smooth feel and to act as a thickening agent. [more]
,
Alcohol Denat.
what‑it‑does antimicrobial/antibacterial | solvent | viscosity controlling
Alcohol with some additives to make it unconsumable. It is great solvent, penetration enhancer, creates cosmetically elegant, light formulas, great astringent, and antimicrobial. In large amounts, it can be very drying to the skin. [more]
,
Magnesium Sulfate
what‑it‑does viscosity controlling
A helper ingredient that is used as a bulking and viscosity controlling agent. It can also be used as a heat generating agent in water-less formulas as it has an instant heat-generating chemical reaction with water.  [more]
,
Propylene Glycol
what‑it‑does moisturizer/humectant | solvent | viscosity controlling
irritancy, com. 0 0
A common glycol that improves the freeze-thaw stability of products. It's also a solvent, humectant and to some extent a penetration enhancer. [more]
,
Carbomer
what‑it‑does viscosity controlling
It’s a handy white powder that magically converts a liquid into a nice gel formula. [more]
,
Hydroxyethylcellulose
what‑it‑does viscosity controlling
A helper ingredient that can thicken up cosmetic products and create beautiful gel formulas. It's derived from cellulose, the major component of the cell wall of green plants. 

Skim through

Ingredient name what-it-does irr., com. ID-Rating
Dimethicone emollient 0, 1
Aqua (Water) solvent
Dimethicone Crosspolymer viscosity controlling
Butylene Glycol moisturizer/​humectant, solvent 0, 1
Glycerin skin-identical ingredient, moisturizer/​humectant 0, 0 goodie
Alcohol Denat. antimicrobial/​antibacterial, solvent, viscosity controlling icky
Sodium Ascorbyl Phosphate antioxidant, anti-acne goodie
Peg/Ppg-18/18 Dimethicone emulsifying
Magnesium Sulfate viscosity controlling
Phenoxyethanol preservative
Cetyl Peg/Ppg-10/1 Dimethicone emulsifying, surfactant/​cleansing
Polyglyceryl-4 Isostearate emulsifying
Hexyl Laurate emollient
Retinyl Palmitate cell-communicating ingredient
Hydrolyzed Rice Protein
Propylene Glycol moisturizer/​humectant, solvent, viscosity controlling 0, 0
Tocopheryl Acetate antioxidant 0, 0
Sorbitan Laurate emulsifying
Salicylic Acid exfoliant, anti-acne, soothing, preservative superstar
Methylparaben preservative
Ethylparaben preservative
Carbomer viscosity controlling
Medicago Sativa (Alfalfa) Extract
Polysorbate 20 emulsifying, surfactant/​cleansing 0, 0
Hydroxyethylcellulose viscosity controlling
Panax Ginseng Root Extract antioxidant, emollient goodie
Morus Alba Leaf Extract
Sodium Benzoate preservative
Acetyl Dipeptide-1 Cetyl Ester cell-communicating ingredient, soothing goodie
Tocopherol antioxidant 2, 2 superstar
Ethylhexylglycerin preservative
Palmitoyl Tripeptide-1 cell-communicating ingredient goodie
Palmitoyl Tetrapeptide-7 cell-communicating ingredient goodie

Ingredients explained

What-it-does: emollient | Irritancy: 0 | Comedogenicity: 1

Probably the cheapest and most common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thick liquid.

As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier. Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it's nice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity. 

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As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it and smoothes the hair like no other thing. Depending on your hair type, it can be a bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types). 

Also-called: Aqua | What-it-does: solvent

Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product. 

It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water. 

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Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying. 

One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time. 

A high-molecular-weight silicone elastomer (rubber-like elastic material) that is usually blended with a base silicone fluid (such as dimethicone or cyclopentasiloxane) to give the formula a silky smooth feel and to act as a thickening agent.

What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1

Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.  

BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.

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It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive. 

Glycerin - goodie
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
  • A natural moisturizer that’s also in our skin
  • Super common, used for more than 50 years
  • Not only a simple moisturizer but plays an important role in keeping the stuff between our skin cells healthy
  • High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>

  • It's a super common and super debated skincare ingredient
  • It has several benefits: great solvent, penetration enhancer, creates cosmetically elegant, light formulas, great astringent and antimicrobial
  • It can be very drying if it's in the first few ingredients on an ingredient list
  • Some experts even think that regular exposure to alcohol damages skin barrier and causes inflammation though it's a debated opinion (read more in geeky details tab)
Read all the geeky details about Alcohol Denat. here >>

Also-called: Form of Vitamin C, SAP | What-it-does: antioxidant, anti-acne

The sodium salt form of skincare superstar, vitamin C. If you do not know what the big fuss about vitamin C is, you are missing out and you have to click here and read all the geeky details about it.

Pure vitamin C (aka ascorbic acid, AA) is great and all, but its lack of stability is a big challenge for the cosmetics industry. One solution is to create stable derivatives that can be absorbed into the skin, convert there to AA and do all the magic AA is proven to do (which is being an antioxidant, a collagen booster, and a skin brightener).

Expand to read more

SAP (the vit C derivative, not the enterprise software, obvs) is a promising derivative that has great stability up to pH 7. The challenge with it though is skin penetration. Unfortunately, it seems to be limited, or to quote a great article from the Journal of Cosmetic Dermatology "topically applied ascorbyl phosphate salts are, at very best, poorly absorbed in comparison with AA". Regarding conversion to AA, there seems to be no data about it, so we can neither deny nor confirm it.

We have better news regarding the three magic abilities of vitamin C: there is in-vivo (tested on real people) data showing that SAP does have photo-protective (aka antioxidant) properties, though less than pure AA. SAP might also aid collagen boosting; in-vitro (made in the lab) data shows that it works, but is less effective than another vitamin C derivative, called MAP (that seems to be as effective as pure AA). As for skin-brightening, there is a trade publication with in-vivo data showing that SAP can fade brown spots

Another thing SAP might be able to do is to help with acne. A 2005 study showed in vitro (in test tubes) that 1% SAP has a strong antimicrobial activity on evil acne causing P. acnes and it also showed in vivo (on real people) that 5% SAP can strongly improve the inflammatory and non-inflammatory lesions of acne vulgaris. In fact, the results were comparable or even slightly better than with 5% benzoyl peroxide. 

And there is even more regarding SAP and acne. A nice double-blind study from 2009 showed that  5% SAP reduced the inflammatory lesions by 20.14% and 48.82% within 4 and 8 weeks respectively and when combined with 0.2% retinol the results were even better. With this combination treatment, the improvement was 29.28% after 4 weeks and 63.10% after 8 weeks of application. 

Aside from research studies, anecdotal evidence also supports SAP being a promising vitamin C derivative. One of the best-selling (vitamin C) serums in Sephora is the Ole Henriksen Truth Serum, while on Amazon it's the OzNaturals Vitamin C 20 Serum. Another popular choice is the Mad Hippie Vitamin C serum, and all of these contain vitamin C in the form of SAP. 

Overall, we think SAP is a goody!  In terms of anti-aging, it's probably not as effective as pure Ascorbic Acid, but it's totally worth a try. However, if your skin is acne-prone, SAP is your form of Vitamin C and it's a must-try.

What-it-does: emulsifying

A silicone emulsifier that helps to create water in silicone emulsions. 

Also-called: Epsom salt | What-it-does: viscosity controlling

A helper ingredient that is used as a bulking and viscosity controlling agent

It can also be used as a heat generating agent in water-less formulas as it has an instant heat-generating chemical reaction with water. 

What-it-does: preservative

It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.

It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic. 

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Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10). 

It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.

Also-called: Cetyl Dimethicone Copolyol | What-it-does: emulsifying, surfactant/cleansing

A silicone emulsifier that helps water and silicone oils to mix nicely together. 

What-it-does: emulsifying

We don't have description for this ingredient yet.

What-it-does: emollient

A fast spreading emollient ester (hexyl alcohol + lauric acid) that's used in water in oil emulsions or in water-free formulas. It gives a light skin feel. 

Also-called: Form of Retinoids | What-it-does: cell-communicating ingredient

It's an ester form of vitamin A (retinol + palmitic acid) that belongs to the "retinoid family". The retinoid family is pretty much the royal family of skincare, with the queen being the FDA-approved anti-aging ingredient tretinoin. Retinol is also a very famous member of the family, but it's like Prince William, two steps away from the throne. Retinyl palmitate will be then little Prince George, quite far (3 steps) away from the throne. 

By steps, we mean metabolic steps. Tretinoin, aka retinoic acid, is the active ingredient our skin cells can understand and retinyl palmitate (RP) has to be converted by our metabolic machinery to actually do something. The conversion is a 3 step one and looks like this:

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retinyl palmitate --> retinol -- > retinaldehyde --> all-trans-retinoic acid

As we wrote in our lengthy retinol description the problem is that the conversion is not terribly effective. The evidence that RP is still an effective anti-aging ingredient is not very strong, in fact, it's weak. Dr. Leslie Baumann in her fantastic Cosmetic Dermatology book writes that RP is topically ineffective

What's more, the anti-aging effectiveness is not the only questionable thing about RP. It also exibits questionable behaviour in the presence of UV light and was the center of a debate between the non-profit group, EWG (whose intentions are no doubt good, but its credibility is often questioned by scientists) and a group of scientists and dermatologists lead by Steven Q. Wang, MD,  director of dermatologic surgery at Memorial-Sloan Kettering Cancer Centre. 

Dr. Leslie Baumann wrote a great review of the debate and summarized the research available about retinyl palmitate here.  It seems that there is a study showing RP being photo protective against UVB rays but there is also a study showing RP causing DNA damage and cytotoxicity in association with UVA. 

We think that the truth lies somewhere in the middle, and we agree with Dr. Baumann's conclusion: "sufficient evidence to establish a causal link between RP and skin cancer has not been produced. Nor, I’m afraid, are there any good reasons to recommend the use of RP". We would add especially during the day!

Bottom line: If you wanna get serious about retinoids, RP is not your ingredient (retinol or tretinoin is!). However, if you use a product that you like and it also contains RP, there is no reason to throw it away. If possible use it at night, just to be on the safe side.

We don't have description for this ingredient yet.

What-it-does: moisturizer/humectant, solvent, viscosity controlling | Irritancy: 0 | Comedogenicity: 0
  • It's a helper ingredient that improves the freeze-thaw stability of products
  • It's also a solvent, humectant and to some extent a penetration enhancer
  • It has a bad reputation among natural cosmetics advocates but cosmetic scientists and toxicology experts do not agree (read more in the geeky details section)
Read all the geeky details about Propylene Glycol here >>

Also-called: Vitamin E Acetate | What-it-does: antioxidant | Irritancy: 0 | Comedogenicity: 0

It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version. 

According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E. 

What-it-does: emulsifying

We don't have description for this ingredient yet.

Salicylic Acid - superstar
Also-called: BHA | What-it-does: exfoliant, anti-acne, soothing, preservative
  • It's one of the gold standard ingredients for treating problem skin
  • It can exfoliate skin both on the surface and in the pores (pH 3-4 needed)
  • It's a potent anti-inflammatory agent
  • It's more effective for treating blackheads than acne
  • For acne combine it with antibacterial agents like benzoyl peroxide or azelaic acid
Read all the geeky details about Salicylic Acid here >>

What-it-does: preservative

The most common type of feared-by-everyone-mostly-without-scientific-reason parabens. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon

Apart from the general controversy around parabens (we wrote about it more here), there is a 2006 in-vitro (made in the lab not on real people) research about methylparaben (MP) showing that when exposed to sunlight, MP treated skin cells suffered more harm than non-MP treated skin cells. The study was not done with real people on real skin but still - using a good sunscreen next to MP containing products is a good idea. (Well, in fact using a sunscreen is always a good idea. :))

What-it-does: preservative

A very common type of feared-by-everyone-mostly-without-scientific-reason paraben. It's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon. Read more about parabens here >>

What-it-does: viscosity controlling

It’s a handy white powder that magically converts a product into a nice gel formula. If you see gel in the name of a moisturiser type thing, chances are carbomer will be in the ingredient list. 

It’s not too common, but sometimes there is also a number after it. The reason for it is that carbomer in itself actually refers to a group of stuff and the number shows the weight and type of the molecule. 

Also-called: Alfalfa

We don't have description for this ingredient yet.

What-it-does: emulsifying, surfactant/cleansing | Irritancy: 0 | Comedogenicity: 0

It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula. 

What-it-does: viscosity controlling

A nice little helper ingredient that can thicken up cosmetic products and create beautiful gel formulas. It's derived from cellulose, the major component of the cell wall of green plants. 

Also-called: True Ginseng, Ginseng, Korean Ginseng | What-it-does: antioxidant, emollient

A  traditional Korean medicine used for more than 2000 years. Regarding skin care, its main thing seems to be enhancing skin nutrition and metabolism as a result of improving blood circulation.

It also contains biologically active components referred to as ginseng saponins (ginsenosides) that have potent antioxidant properties

We don't have description for this ingredient yet.

What-it-does: preservative

A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi. 

It’s pH dependent and works best at acidic pH levels (3-5). It’s not strong enough to be used in itself so it’s always combined with something else, often with potassium sorbate.

Also-called: Calmosensine | What-it-does: cell-communicating ingredient, soothing

 A soothing dipeptide (tyrosine + arginine) based molecule that functions as a "messenger of tranquility and muscle relaxation". It works via stimulating the skin nerve cells to release met-enkephalin, which is an opioid (i.e. relaxing, pain-relieving) messenger molecule. 

This means that Acetyl Dipeptide-1 Cetyl Ester can "signal" our skin cells to "relax" and it can instantly decrease skin irritations coming from heat, chemical stinging or mechanical stresses. It is also claimed to be able to prevent the onset of wrinkles and expression lines thanks to its muscle relaxation properties.

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Regarding the research, we could find one study that compared the calming effects of our guy with the soothing molecule called 4-T-Butylcyclohexanol. They irritated the skin with Capsaicin (the active in chili peppers) and examined how the test products relieved the burning/stinging sensation. They found that both molecules worked, but 4-t-Butylcyclohexanol worked somewhat better. 

Tocopherol - superstar
Also-called: Vitamin E | What-it-does: antioxidant | Irritancy: 2 | Comedogenicity: 2
  • Primary fat-soluble antioxidant in our skin
  • Significant photoprotection against UVB rays
  • Vit C + Vit E work in synergy and provide great photoprotection
  • Has emollient properties
  • Easy to formulate, stable and relatively inexpensive
Read all the geeky details about Tocopherol here >>

What-it-does: preservative

If you have spotted ethylhexylglycerin on the ingredient list, most probably you will see there also the current IT-preservative, phenoxyethanol. They are good friends because ethylhexylglycerin can boost the effectiveness of phenoxyethanol (and other preservatives) and as an added bonus it feels nice on the skin too.

Also, it's an effective deodorant and a medium spreading emollient

Also-called: Part of Matrixyl 3000, Pal-GHK, Formerly also Palmitoyl Oligopeptide | What-it-does: cell-communicating ingredient

A really famous peptide that is part of Matrixyl 3000, the most sold peptide complex in the word. Before we go and find out what the big deal with Matrixyl 3000 is, let's just focus on Palmitoyl Tripeptide-1 itself for a bit.

It's a small three amino acid (they are the building blocks of all proteins) peptide with the amino sequence of glycine-histidine-lysine, or GHK. GHK is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration. 

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The GHK part is the important one as it's a type I collagen fragment. When collagen naturally breaks down in the skin, the resulting peptide fragments signal to the skin that it should get to work and create some nice, new collagen. Adding in collagen fragment peptides, like GHK, might trick the skin into thinking that collagen has broken down and it's time to create some more.

Therefore, Palmitoyl Tripeptide-1 is believed to be able to stimulate collagen production in the skin, and more collagen means fewer wrinkles and younger looking skin. 

In Matrixyl 3000, Palmitoyl Tripeptide-1 is coupled with Palmitoyl Tetrapeptide-7  and the duo works in synergy to reduce wrinkles and give younger looking skin. According to the manufacturer's in-vivo (made on real people) test, applying 3% Matrixyl 3000 twice a day for 2 months resulted in all of the following things:

  • 39.4% reduction in surface occupied by deep wrinkles
  • 32.9% reduction in main wrinkle density
  • 19.9% reduction in main wrinkle average depth
  • 16% improvement in roughness
  • 16.2% in lifting effect
  • 5.5% improvement in elasticity
  • 15.5% improvement in skin tone

Manufacturer results, of course, always have to be taken with a pinch of salt, but if you like peptides, the Matryxil 3000 duo is one of the best-proven and most well-known ones and it's something that is worth trying.

Also-called: Part of Matrixyl 3000, Pal-GQPR, Previously Palmitoyl Tetrapeptide-3 | What-it-does: cell-communicating ingredient

A four amino acid peptide with the amino sequence of glycine-glutamine-proline-arginine. It is attached to palmitic acid (a fatty acid)  to increase oil solubility and skin penetration. 

It works by reducing the production of the signal moleculeinteleukin-6 (IL-6) which promotes inflammation in the skin and less inflammation means slower degradation of important things (like collagen) that results in younger looking skin for a longer time. 

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It works in synergy with its pal, Palmitoyl Tripeptide-1 in the famous Matrixyl 3000 complex. You can read some more about the famous duo here.

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