003-hy | Hydrating Face Cream
Ingredients overview
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Good Science Beauty 003-hy | Hydrating Face CreamIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
Unless you live under a rock you must have heard about shea butter. It's probably the most hyped up natural butter in skincare today. It comes from the seeds of African Shea or Karite Trees and used as a magic moisturizer and emollient.
But it's not only a simple emollient, it regenerates and soothes the skin, protects it from external factors (such as UV rays or wind) and is also rich in antioxidants (among others vitamin A, E, F, quercetin and epigallocatechin gallate). If you are looking for rich emollient benefits + more, shea is hard to beat.
Sunflower does not need a big intro as you probably use it in the kitchen as cooking oil, or you munch on the seeds as a healthy snack or you adore its big, beautiful yellow flower during the summer - or you do all of these and probably even more. And by even more we mean putting it all over your face as sunflower oil is one of the most commonly used plant oils in skincare.
It’s a real oldie: expressed directly from the seeds, the oil is used not for hundreds but thousands of years. According to The National Sunflower Association, there is evidence that both the plant and its oil were used by American Indians in the area of Arizona and New Mexico about 3000 BC. Do the math: it's more than 5000 years – definitely an oldie.
Our intro did get pretty big after all (sorry for that), so let's get to the point finally: sunflower oil - similar to other plant oils - is a great emollient that makes the skin smooth and nice and helps to keep it hydrated. It also protects the surface of the skin and enhances the damaged or irritated skin barrier. Leslie Bauman notes in Cosmetic Dermatology that one application of sunflower oil significantly speeds up the recovery of the skin barrier within an hour and sustains the results 5 hours after using it.
It's also loaded with fatty acids (mostly linoleic (50-74%) and oleic (14-35%)). The unrefined version (be sure to use that on your skin!) is especially high in linoleic acid that is great even for acne-prone skin. Its comedogen index is 0, meaning that it's pretty much an all skin-type oil.
Truth be told, there are many great plant oils and sunflower oil is definitely one of them.
The oil coming from the seeds of the yellow flowered safflower plant. Similar to other plant oils, it's loaded with nourishing and moisturizing fatty acids: it's a high linoleic acid oil (70%) and has only smaller amounts of oleic acid (11%) (this might be great for acne-prone skin). It also contains antioxidant vitamin E (44mg/100g alpha-tocopherol).
A light yellow liquid ester that gives a slightly dry, silky emollience on the skin. Its unique property is that it is both water-soluble as well as castor oil soluble. This dual solubility is a rare trait that enables the addition of water into waterless formulas, such as lipsticks or balms.
Glycereth-7 Trimethyl Ether is also very pH stable and dissolves salicylic acid so it can be a nice helper ingredient in alcohol-free (alcohol is a very good solvent for SA) salicylic acid formulas.
Isosorbide Dicaprylate (IDC) is a smart, oil-loving skin hydrator and barrier builder molecule. It works synergistically with glycerin as it up-regulates Aquaporin 3 (AQP3), an important transmembrane protein that transports our beloved friend glycerin, along with its’ hydrating groupie water molecules that surround it, into the cell. To put it more simply - AQP3 makes sure that glycerin and water are well distributed in the outer layer of the skin and thus the skin is well-hydrated.
IDC is also claimed to upregulate the expression of CD44 (a hyaluronic acid binding receptor), ceramide synthase (an enzyme required for ceramide synthesis), and decrease transepidermal water loss (TEWL).
The clinical study done by the manufacturer showed that a direct comparison between 2% IDC versus 2% glycerin lotions revealed a three-fold advantage of IDC in giving skin hydration. Severely dry skin treated with 2% IDC + 2% glycerin showed 133% improvement, whereas 35% improvement was observed with moderately dry skin.
- A multi-functional skincare superstar with several proven benefits for the skin
- Great anti-aging, wrinkle smoothing ingredient used at 4-5% concentration
- Fades brown spots alone or in combination with amino sugar, acetyl glucosamine
- Increases ceramide synthesis that results in a stronger, healthier skin barrier and better skin hydration
- Can help to improve several skin conditions including acne, rosacea, and atopic dermatitis
A white powdery thing that's the major component of glass and sand. In cosmetics, it’s often in products that are supposed to keep your skin matte as it has great oil-absorbing abilities. It’s also used as a helper ingredient to thicken up products or suspend insoluble particles.
A type of oil soluble vitamin F that is used as an emollient. Read more at ethyl oleate.
It's the chemically chopped up version of normal lecithin. Most often it's used to create liposomes and to coat and stabilize other ingredients.
A handy multifunctional ingredient that works as a preservative booster, as well as an antioxidant and soothing agent.
A helper ingredient that functions as a film-forming polymer (big molecule from repeated subunits).
It usually comes to the formula as part of a thickener-emulsifier trio paired with Polyisobutene and Polysorbate 20. The three togeather have excellent thickening properties with remarkable emulsifying-stabilising abilities. They also have a nice silicone feel with glide-on spreading.
We don't have description for this ingredient yet.
A polymer (big molecule from repeated subunits) that's used as a gloss improver for lipsticks and lipglosses. Its stickiness also helps lip products to stay on longer.
Combined with polyacrylate-13 and polysorbate 20, it forms a very effective tickener-emulsifier trio.
It's a helper ingredient that helps to thicken up formulas and form a nice gel texture. It leaves a rich, elegant feel with a velvety finish on the skin and works over a wide pH range.
It's a common little helper ingredient that helps water and oil to mix together. Also, it can help to increase the solubility of some other ingredients in the formula.
It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.
As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution".
In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).
What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists.
If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
Though its name says acid, it's not really an exfoliant. It's a plant extract with some antioxidant properties. Its main thing in cosmetic products is to neutralize the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes. It's a natural alternative to sometimes bad-mouthed chelating agents, EDTAs.
A fatty acid that can be found naturally in the skin. In fact, it's the most common saturated fatty acid found in animals and plants.
As for skincare, it can make the skin feel nice and smooth in moisturizers (emollient) or it can act as a foam building cleansing agent in cleansers. It's also a very popular ingredient in shaving foams.
A helper ingredient that helps to make the products stay nice longer, aka preservative. It works mainly against fungi and has only milder effect against bacteria.
It is Ecocert and Cosmos approved, and is popular in natural products.
We don't have description for this ingredient yet.
Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of skincare big shot Vitamin C. If you do not know, why Vitamin C is such a big deal in skincare, click here and read all about it. We are massive vitamin C fans and have written about it in excruciating detail.
So now, you know that Vitamin C is great and all, but it's really unstable and gives cosmetics companies many headaches. To solve this problem they came up with vitamin C derivatives, and one of them is Tetrahexyldecyl Ascorbate (let's call it THDA in short).
It's a really promising candidate (see below), but while reading all the goodness about it in a minute, do not forget that derivatives not only have to be absorbed into the skin but also have to be converted to pure vitamin C (ascorbic acid or AA) and the efficacy of the conversion is often unknown. In addition, vitamin C's three magic properties (antioxidant, collagen booster, skin brightener) are all properly proven in-vivo (on real people), but for the derivatives, it's mostly in-vitro studies or in the case of THDA, it's in-vitro and done by an ingredient supplier.
With this context in mind let's see what THDA might be able to do. First, it is stable (if pH < 5), easy to formulate, and a joy to work with for a cosmetic chemist.
Second, because it's oil-soluble, its skin penetration abilities seem to be great. So great in fact, that it surpasses the penetration of pure vitamin C threefold at the same concentration and it penetrates successfully into the deeper layers of the skin (that is usually important to do some anti-aging work). There is also in-vitro data showing that it converts to AA in the skin.
Third, THDA seems to have all three magic abilities of pure vitamin C: it gives antioxidant protection from both UVB and UVA rays, it increases collagen synthesis (even more than AA) and it has a skin brightening effect by reducing melanogenesis by more than 80% in human melanoma cell cultures.
So this all sounds really great, but these are only in-vitro results at this point. We could find Tetrahexyldecyl Ascorbate mentioned only in one published in-vivo study that examined the anti-aging properties of a silicone formula containing 10% AA and 7% THDA. The authors theorized that the 10% AA is released slowly from the silicon delivery system and probably stays in the upper layer of the skin to give antioxidant benefits, while THDA penetrates more rapidly and deeply and gives some wrinkle-reducing benefits. The study was a small (10 patients), double-blind experiment, and the formula did show some measurable anti-aging results. However, it is hard to know how much pure vitamin C or THDA can be thanked.
Bottom line: a really promising, but not well-proven vitamin C derivative that can be worth a try especially if you like experimenting (but if you like the tried and true, pure vitamin C will be your best bet).
It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version.
According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E.
We don't have description for this ingredient yet.
It's an ester form of vitamin A (retinol + palmitic acid) that belongs to the "retinoid family". The retinoid family is pretty much the royal family of skincare, with the king being the FDA-approved anti-aging ingredient tretinoin. Retinol is also a very famous member of the family, but it's like Prince George, two steps away from the throne. Retinyl palmitate will be then Prince Charlotte (George's little sister), quite far (3 steps) away from the throne.
By steps, we mean metabolic steps. Tretinoin, aka retinoic acid, is the active ingredient our skin cells can understand and retinyl palmitate (RP) has to be converted by our metabolic machinery to actually do something. The conversion is a 3 step one and looks like this:
retinyl palmitate --> retinol -- > retinaldehyde --> all-trans-retinoic acid
As we wrote in our lengthy retinol description the problem is that the conversion is not terribly effective. The evidence that RP is still an effective anti-aging ingredient is not very strong, in fact, it's weak. Dr. Leslie Baumann in her fantastic Cosmetic Dermatology book writes that RP is topically ineffective.
What's more, the anti-aging effectiveness is not the only questionable thing about RP. It also exibits questionable behaviour in the presence of UV light and was the center of a debate between the non-profit group, EWG (whose intentions are no doubt good, but its credibility is often questioned by scientists) and a group of scientists and dermatologists lead by Steven Q. Wang, MD, director of dermatologic surgery at Memorial-Sloan Kettering Cancer Centre.
Dr. Leslie Baumann wrote a great review of the debate and summarized the research available about retinyl palmitate here. It seems that there is a study showing RP being photo protective against UVB rays but there is also a study showing RP causing DNA damage and cytotoxicity in association with UVA.
We think that the truth lies somewhere in the middle, and we agree with Dr. Baumann's conclusion: "sufficient evidence to establish a causal link between RP and skin cancer has not been produced. Nor, I’m afraid, are there any good reasons to recommend the use of RP". We would add especially during the day!
Bottom line: If you wanna get serious about retinoids, RP is not your ingredient (retinol or tretinoin is!). However, if you use a product that you like and it also contains RP, there is no reason to throw it away. If possible use it at night, just to be on the safe side.
A tiny peptide with only two amino acids (amino acids are the building block of proteins, and peptides are a few amino acids attached together), Valine and Tryptophan. It's part of a 3 actives complex called Eyeliss (with HMC and Palmitoyl Tetrapeptide-7) that's supposed to fight under-eye bags.
The manufacturer claims that this dipeptide in Eyeliss can increase lymphatic circulation and the three actives together represent a "global approach to treating puffy eyes". The clinical study of the manufacturer with 20 people and 3% Eyeliss showed improvement after 56 days for 70% of the participants.
We don't have description for this ingredient yet.
We have to start by writing how fascinated we are by the amazing lavender fields of Provance and we do love pretty much everything about lavender: its look, its color, its scent.... but, when it comes to skincare, lavender is a questionable ingredient that you probably do not want in your skincare products.
First, let us start with the pros: it has a lovely scent, so no wonder that it is popular as a fragrance ingredient in natural products wanting to be free from synthetic fragrances but still wanting to smell nice. The scent of lavender is famous for having calming and relaxing properties and some smallish scientific studies do support that. Inhaled volatile compounds seem to have a soothing effect on the central nervous system and studies have shown that lavender aromatherapy can improve patient's anxiety and experience in hospitals.
Another pro is that lavender oil has some nice antimicrobial and antibacterial properties. It also has some local pain relieving and muscle relaxing magical powers. Lavender oil is also often claimed to have anti-inflammatory properties. We have found a study confirming this but it was the essential oil of the leaves and not the much more commonly used flowers and the two differ in their main chemical compounds very much. (The main components of the flower essential oil are linalyl acetate and linalool [around 80% the two together] while it is 1,8-Cineole [around 65%] in the essential oil of the leaves.)
Now, let us look at the cons: similar to a bunch of other essential oils, the main components of lavender oil are potentially irritating fragrant components. The two main components are linalyl acetate (about 50%) and linalool (about 35%) and both autoxidise on exposure to the air forming strong contact allergens. To make things even worse, lavender oil seems to be cytotoxic from concentrations as low as 0.25% (concentration up to 0.125% were ok).
There is also an often cited Japanese study that made patch tests with lavender oil for 9 years and found a huge increase in lavender oil sensitivity in 1997 (from 1.1% in 1990 to 8.7% in 1997 and 13.9% in 1998). This was the year when using dried lavender flowers in pillows, wardrobes, and elsewhere became fashionable in Japan, so it seems that increased exposure to lavender results in increased risk of sensitivity.
Overall, it makes us sad to write bad things about such a lovely plant, but when it comes to skincare, you will be better off without lavender.
A semi-essential (infants cannot synthesize it, but adults can) amino acid that is one of the primary building blocks of hair keratin and skin collagen. It's a natural moisturizing factor, a skin hydrator and might also help to speed up wound healing.
Arginine usually has a positive charge (cationic) that makes it substantive to skin and hair (those are more negatively charged surfaces) and an excellent film former. Thanks to the positive charge, it also creates a complex with AHAs (AHAs like to lose a hydrogen ion and be negatively charged, so the positive and the negative ions attract each other) that causes a "time-release AHA effect" and reduces the irritation associated with AHAs.
A non-essential amino acid (the building blocks of skin proteins, like collagen or elastin), that the body can produce itself, but its production decreases with age. When you put it all over your face, it works as a moisturizer and maybe more.
According to great skincare blog Futurederm, glycine might help with wound healing and tissue repair and when used together with other amino acids, leucine and proline it might improve wrinkles.
BTW, it's also a building block of a bunch of important and famous peptides, including copper-tripeptide-1, palmitoyl tripeptide-1 or palmitoyl hexapeptide-12.
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| what‑it‑does | solvent |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | emollient |
| what‑it‑does | emollient |
| irritancy, com. | 0, 0 |
| what‑it‑does | antioxidant | emollient |
| irritancy, com. | 0, 0-2 |
| what‑it‑does | emollient |
| what‑it‑does | cell-communicating ingredient | moisturizer/humectant |
| what‑it‑does | cell-communicating ingredient | skin brightening | anti-acne | moisturizer/humectant |
| what‑it‑does | viscosity controlling |
| what‑it‑does | emollient | perfuming |
| what‑it‑does | emollient | emulsifying |
| what‑it‑does | antioxidant |
| what‑it‑does | emollient | viscosity controlling |
| what‑it‑does | viscosity controlling |
| what‑it‑does | viscosity controlling |
| what‑it‑does | emulsifying | surfactant/cleansing |
| irritancy, com. | 0, 0 |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | chelating |
| what‑it‑does | skin-identical ingredient | emollient | emulsifying |
| irritancy, com. | 0, 2 |
| what‑it‑does | preservative |
| what‑it‑does | emulsifying |
| what‑it‑does | antioxidant | skin brightening |
| what‑it‑does | antioxidant |
| irritancy, com. | 0, 0 |
| what‑it‑does | chelating |
| what‑it‑does | emollient |
| what‑it‑does | cell-communicating ingredient |
| irritancy, com. | 1-3, 1-3 |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | antimicrobial/antibacterial | perfuming |
| what‑it‑does | abrasive/scrub |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | skin-identical ingredient |