Acure

Radically Rejuvenating Whipped Night Cream

An ester that comes from Cetearyl alcohol and the fatty acids of olive oil. It often comes to the formula coupled with Sorbitan Olivate as the two together form the well-known, natural emulsifier trade named Olivem 1000. 

Other than helping oil and water to blend, the main thing of Olivem 1000 is generating liquid crystal structures that are similar to the lipid structures of the stratum corneum (the outermost layer of the skin). Thanks to this, Olivem 1000 doubles as an active ingredient with significant moisturizing, barrier-repairing and soothing properties.

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An ester coming from sorbitol and the fatty acids of olive oil. It is part of the popular emulsifier trade named Olivem 1000 that is well-known for generating biomimetic liquid crystal structures. We have more info on Olivem 1000 at Cetearyl Olivate >>

If you have an interest in elephants and Africa, you have probably heard of elephants getting drunk from the fruit of the Marula tree. Though this seems to be only a legend, what is true is that the Marula fruit is really nice (and elephants do love to eat it) and there is a stone in it with several oil-rich kernels inside. 

So the Marula oil - similar to many other plant oils - is a really nice nourishing and moisturizing oil that can improve skin hydration and smoothness and it can even reduce skin redness. It's traditionally used in South Africa to massage babies with and as a body lotion for face, feet, and hands.

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We don't have description for this ingredient yet.

Sh-Oligopeptide-1 is the famous molecule, which is also called Epidermal Growth Factor or EGF. Chemically speaking, Growth Factors are largish peptides or smallish proteins, or to put it in another way, medium-length amino acid sequences (EGF consists of 53 amino acids).  Biologically speaking, Growth Factors are cellular signal molecules that can stimulate cell growth, proliferation, healing and/or differentiation. 

There are lots of Growth Factors and EGF is just one of them. The topic of "Growth Factors and skincare" is a big, confusing and controversial one and we will try our best to summarize the story for you, including the pros and the cons. 

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Sh-Oligopeptide-2 is also called Insulin-like growth factor 1 and it belongs to the same group of ingredients (Growth Factors) as its better-known sister, Epidermal Growth Factor or Sh-Oligopeptide-1. This guy consists of 70 amino acids and, similar to EGF, it is also claimed to stimulate cell proliferation and wound healing. There is also a study that indicates EGF and IGF1 work in synergy to promote keratinocyte (skin cell) proliferation. 

The topic of Growth Factors in skincare is complex and controversial. If you are new to it, read our shiny explanation on EGF to get a (hopefully) balanced impression about the pros and cons.

Sh-Polypeptide-1 is a cell signaling protein also called Basic Fibroblast Growth Factor and is twin sister to Acidic Fibroblast Growth Factor. We can write here pretty much the same things as we did on aFGF: it is a mitogenic (= stimulates cell proliferation) ingredient that stimulates fibroblast cell growth and proliferation. According to manufacturer info, it also stimulates the synthesis of collagen and other extracellular-matrix (the gooey stuff between cells) components. 

Growth Factors and skincare is a big, complicated and controversial topic, so if you wanna know more, we have a more detailed explanation on Epidermal Growth Factor, the most common one used in skincare.

Sh-Polypeptide-9 is a cell signaling protein also called Vascular Endothelial Growth Factor. As its name suggests, its main function is to stimulate the formation of blood vessels. As to what it does in cosmetic products, we found manufacturers info claiming that it plays a role in supplying fibroblast cells (VIP skin cells that make collagen) with nutrients, in the growth and migration of cells and in wound healing. 

It usually comes to the formula as part of a Growth Factor mix trade named BIO-Placenta, that combines EGF, IGF-1, FGF1, FGF2 and this guy to form a synergistic growth factor cocktail. BIO Placenta is claimed to do pretty much everything you would want from an anti-aging active including anti-wrinkle, skin rejuvenation, elasticity enhancement, moisturizing and cell vitalization properties. 

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Sh-Polypeptide-11 is a medium sized cell signaling molecule also called Acidic Fibroblast Growth Factor. It belongs to the same group of ingredients (Growth Factors) as its better-known sister, Epidermal Growth Factor or Sh-Oligopeptide-1. As its name suggests, FGF can stimulate the growth and proliferation of fibroblast cells (VIP cells that produce among other things collagen). According to manufacturer info, it also stimulates skin regeneration, wound healing and collagen and elastin synthesis. 

As for research, we could find an in-vitro study that proved that "Recombinant FGF-1 strongly stimulated fibroblast and keratinocyte proliferation. However, the transition of this protein through the SC required an appropriate carrier system - lipid spheres." 

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Copper Palmitoyl Heptapeptide-14 is the payload peptide (a short chain of amino acids) in the encapsulated copper peptide technology trade named X50 Antiaging. The delivery system (called The Cosmetic Drone) is a high-tech capsule where our peptide is wrapped in a biocompatible polymer shell (created from Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol) and another peptide, which has an affinity to the fibroblast receptors, sits on the outside of the capsule and guides it to the right place in the skin. 

The right place in this case is the fibroblast cell (the important collagen-producing cell in the dermis), so once Copper Palmitoyl Heptapeptide-14 is there, it promotes the gene expression of both collagen and elastin. According to the 30-person in-vivo (made on real humans) test of the manufacturer, the participants experienced an average of 33% reduction in wrinkles and 19% increase in elasticity in 28 days. 

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Heptapeptide-15 Palmitate is the targeting peptide (a short chain of amino acids) that is part of the encapsulated copper peptide technology trade named X50 Antiaging. This smart guy sits at the outer part of the encapsulation shell and seeks out the all-important collagen-producing cells in the middle layer of the skin called fibroblasts. 

Once Heptapeptide-15 Palmitate binds to the receptors of the fibroblast, the cell internalizes the capsule, and the payload (in this case Copper Palmitoyl Heptapeptide-14) is released.  Continue here to read what the payload peptide is doing once it arrives at its target, the fibroblast cell. 

A four amino acid peptide with the amino sequence of glycine-glutamine-proline-arginine. It is attached to palmitic acid (a fatty acid)  to increase oil solubility and skin penetration. 

It works by reducing the production of the signal molecule, interleukin-6 (IL-6) which promotes inflammation in the skin and less inflammation means slower degradation of important things (like collagen) that results in younger looking skin for a longer time. 

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A really famous peptide that is part of Matrixyl 3000, the most sold peptide complex in the word. Before we go and find out what the big deal with Matrixyl 3000 is, let's just focus on Palmitoyl Tripeptide-1 itself for a bit.

It's a small three amino acid (they are the building blocks of all proteins) peptide with the amino sequence of glycine-histidine-lysine, or GHK. GHK is attached to palmitic acid (a fatty acid) to increase oil solubility and skin penetration. 

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Ferulic Acid (FA) is a goodie that can be found naturally in plant cell walls. There is a lot of it especially in the bran of grasses such as rice, wheat and oats. 

FA - whose main job is to be an antioxidant - owes its fame to a 2005 research that discovered that adding in 0.5% FA to a 15% Vitamin C + 1% Vitamin E solution not only stabilizes the highly unstable, divaish Vit C, but it also doubles the photoprotection abilities of the formula. 

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We don't have description for this ingredient yet.

Coconut Alkanes is a volatile (something that does not absorb into the skin but evaporates from it), naturally derived vegetable alkane coming from renewable sources. It is a light, oily liquid that works as an emollient and gives a smooth skin feel.

It's often combined with another emollient called Coco-Caprylate/Caprate and the two together can serve as a great replacement for some volatile silicones, like Cyclopentasiloxane. 

A biotechnologically derived ingredient that is produced by the fermentation of a marine bacteria living in the cold Antarctic Ocean. According to the manufacturer's info, it seems to have two different sets of magic properties: 

The first set includes skin-protecting and anti-aging abilities: it can help to protect the skin from dryness and redness due to cold weather and it also promotes skin regeneration and smoother skin surface by stimulating protein synthesis in the skin.  More specifically, these proteins are type I and IV collagen and elastin, all super important stuff for wrinkle-free, young looking skin (though these results came only from in-vitro tests and might or might not apply to living human skin). 

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• It's one of the gold standard ingredients for treating problem skin
• It can exfoliate skin both on the surface and in the pores
• It's a potent anti-inflammatory agent
• It's more effective for treating blackheads than acne
• For acne combine it with antibacterial agents like benzoyl peroxide or azelaic acid

A light emollient ester (C8-10 fatty acids connected to C12-18 fatty alcohols) that absorbs quickly and leaves a dry but silky finish on the skin. In terms of skin feel, it is similar to Dicaprylyl Carbonate, another commonly used light emollient. 

It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here.  The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.

As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit  "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution". 

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A non-essential amino acid  (important building block of collagen and elastin) that hydrates the skin. It is also used to set the pH of the cosmetic product (buffering).

The famous omega-6 fatty acid, the mother of all ω-6 fatty acids in our body. It is a so-called polyunsaturated fatty acid meaning it has more than one (in this case two) double bonds and a somewhat kinky structure that makes LA and LA-rich oils a thin liquid.

It is also an essential fatty acid meaning our body cannot synthesize it and has to take it from food. This is not hard at all as plenty of nuts (such as flax, poppy or sesame seeds) and vegetable oils (such as sunflower or safflower) are rich in LA. The hard thing seems to be eating enough omega-3-s, more specifically eating a healthy ratio of omega-6 to omega-3, but that is a topic for a what-is-good-to-eat-site and not for us. 

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The famous omega-3 fatty acid, the mother of all ω-3 fatty acids in our body. Next to linoleic acid, it is the other essential fatty acid that our body cannot synthesize and we have to ingest it from our food. It is also a PUFA, aka polyunsaturated fatty acid with three double bonds, a kinky chemical structure and thus a liquid consistency.

While linoleic acid is abundant in the skin, this is not the case with alpha-linolenic acid (ALA). It is not entirely clear if it is meant to be like that or if this is a consequence of not eating enough Omega-3 with the typical Western diet.

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A very common ingredient that can be found in all cell membranes. In cosmetics it's quite the multi-tasker: it's an emollient and water-binding ingredient but it's also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes. 

PCA stands for Pyrrolidone Carboxylic Acid and though it might not sound like it, it is a thing that can be found naturally in our skin. The sodium salt form of PCA is an important skin-identical ingredient and great natural moisturizer that helps the skin to hold onto water and stay nicely hydrated. 

PCA stands for Pyrrolidone Carboxylic Acid and though it might not sound like it, it is a thing that can be found naturally in our skin. In fact, after amino acids, it is the second biggest NMF component of the skin with 12% being PCA of the NMF composition of normal skin.  So similar to other NMFs, it's a skin goodie that helps the skin to hold onto water and stay nicely hydrated. 

A handy helper ingredient that helps water and oil to mix nicely together, aka emulsifier. It is especially recommended for protective, baby care and general purpose emollient creams. 

It also helps to disperse insoluble particles (think color pigments or zinc/titanium dioxide sunscreen) nice and even in cosmetic formulas. 

We don't have description for this ingredient yet.

Turmeric is the yellow spice you probably know from curry and Indian food. It's also a traditional herbal medicine used in Ayurveda for its bunch of anti-something magic abilities including being anti-inflammatory, antimicrobial, antioxidant and anticarcinogenic. 

As for turmeric and skincare, we have good news: studies show that the root extract and its main biologically active component, curcumin can do multiple good things for the skin. Thanks to its anti-inflammatory and antimicrobial activity, it shows some promise for acne-prone skin and a small study from 2013 showed that it might be able to regulate sebum production. 

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We don't have description for this ingredient yet.