Regeneration Cream Line F
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Susanne Kaufmann Regeneration Cream Line FIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
We don't have description for this ingredient yet.A multi-functional, silky feeling helper ingredient that can do quite many things. It's used as an emulsion stabilizer, solvent and a broad spectrum antimicrobial. According to manufacturer info, it's also a moisturizer and helps to make the product feel great on the skin. It works synergistically with preservatives and helps to improve water-resistance of sunscreens.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
Sunflower does not need a big intro as you probably use it in the kitchen as cooking oil, or you munch on the seeds as a healthy snack or you adore its big, beautiful yellow flower during the summer - or you do all of these and probably even more. And by even more we mean putting it all over your face as sunflower oil is one of the most commonly used plant oils in skincare.
It’s a real oldie: expressed directly from the seeds, the oil is used not for hundreds but thousands of years. According to The National Sunflower Association, there is evidence that both the plant and its oil were used by American Indians in the area of Arizona and New Mexico about 3000 BC. Do the math: it's more than 5000 years – definitely an oldie.
Our intro did get pretty big after all (sorry for that), so let's get to the point finally: sunflower oil - similar to other plant oils - is a great emollient that makes the skin smooth and nice and helps to keep it hydrated. It also protects the surface of the skin and enhances the damaged or irritated skin barrier. Leslie Bauman notes in Cosmetic Dermatology that one application of sunflower oil significantly speeds up the recovery of the skin barrier within an hour and sustains the results 5 hours after using it.
It's also loaded with fatty acids (mostly linoleic (50-74%) and oleic (14-35%)). The unrefined version (be sure to use that on your skin!) is especially high in linoleic acid that is great even for acne-prone skin. Its comedogen index is 0, meaning that it's pretty much an all skin-type oil.
Truth be told, there are many great plant oils and sunflower oil is definitely one of them.
It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version.
According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E.
Chamomile probably needs no introduction as it's one of the most widely used medicinal herbs. You probably drink it regularly as a nice, calming cup of tea and it's also a regular on skincare ingredient lists.
Cosmetic companies use it mainly for its anti-inflammatory properties. It contains the terpenoids chamazulene and bisabolol both of which show great anti-inflammatory action in animal studies. On top of that chamomile also has some antioxidant activity (thanks to some other active ingredients called matricine, apigenin and luteolin).
Though chamomile is usually a goodie for the skin, it's also not uncommon to have an allergic reaction to it.
A spray-dried or freeze-dried version of Aloe Leaf Juice. The point of both drying methods is to make water evaporate from the juice and leave just the "useful" components behind.
So the aloe powder has similar soothing, emollient and moisturizing properties as the juice. You can read a bit more about the juice here.
It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.
As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution".
In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).
What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists.
If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
Witch hazel is a smallish tree (up to 5m) that's native to North-America, has nice yellow flowers and is similar to the hazelnut bush (hence the name).
As for skincare, it's loaded with active components that have a bunch of magic properties, like astringent, anti-inflammatory, antioxidant and anti-bacterial. It's also a well-known vasoconstrictor (it makes the blood vessels narrower) and promotes the healing of broken skin by tightening up the skin proteins and thus creating a protective covering.
The complication, however, is that different extracts and distillates can be made from different parts of the plant (bark, twigs, and leaves are typically used) and different extraction methods from different parts produce different results. So if you see only Witch Hazel Extract or Witch Hazel Water on the ingredient list, it's a bit hard to know what you're actually getting but we will try to summarize the possibilities to give an idea.
The main biologically active components in Witch Hazel are hamamelitannin (a potent astringent and antioxidant), catechins (anti-inflammatory and antioxidant) and gallic acid (antibacterial). The bark extract contains by far the most hamamelitannin and it has the most gallic acid and catechins. The twigs contain fewer catechins, less gallic acid, and much less hamamelitannin (4.77% vs 0.18%). The leaves contain hardly any tannins (0.04%) or catechins and contain a medium amount of gallic acid (compared to the bark and twigs).
Witch Hazel also contains tiny amounts of the essential oil and fragrance component eugenol, but the amount is so small that it's probably not significant for the skin.
Apart from the differences in active components in different parts of the Witch Hazel bush, the extraction methods also vary. Witch Hazel Distillate contains 14% added alcohol according to the USP specifications and alcohol is, at best drying, and at worst skin-damaging. Luckily, there are also alcohol-free distillates, so if you prefer no alcohol check the ingredient list carefully. Witch Hazel Extracts can also be made in different ways: browsing Ulprospector, we could find hydroglycolic, hydroalcoholic and glicerine/water based extracts.
Well-known skin care expert, Paula Begoun rates witch hazel as poor and says, "depending on the form of witch hazel, you’re exposing your skin either to a sensitizing amount of alcohol or to tannins, or both." This might be the case if you are dealing with an alcoholic witch hazel bark water or extract, but looking at CosIng (the official INCI name listing of the EU), witch hazel bark water or witch hazel bark extract are not listed ingredients. Bark and leaf or bark and twig or all three are used together to create extracts, so the chance that there is too much hamamelitannin in the final cosmetic ingredient seems small. Also alcohol-free extracts and distillates exist; actually, the majority seem to be alcohol-free nowadays. So all in all, we think "Hamamelis Virginiana Extract" on the ingredient list is nothing to worry about.
We even found a German study that compared the efficacy of Hamamelis ointment to panthenol ointment for soothing the skin in children (from 27 days to 11 years old). They observed 309 children and concluded that both ointments were similarly effective but the one with Hamamelis was even better tolerated (98.2% vs. 92.3% tolerated well the ointments in the two groups).
All in all, Witch Hazel Extract is a sloppy INCI name (btw, not in the CosIng listing), and you do not really know what you're getting. Most probably though, you are getting a goody with nice astringent, soothing, antibacterial, and even antioxidant properties.
We all know honey as the sweet, gooey stuff that is lovely to sweeten a good cup of tea and we have good news about putting honey all over our skin. It is just as lovely on the skin as it is in the tea.
The great review article about honey in the Journal of Cosmetic Dermatology writes that it is arguably the oldest skincare ingredient and evidence from around 4500 BC mentions honey in some eye cream recipes. Chemically speaking, it is a bee-derived, supersaturated sugar solution. About 95% of honey dry weight is sugar and the other 5% consists of a great number of other minor components including proteins, amino acids, vitamins, enzymes, and minerals.
This unique and complex chemical composition gives honey a bunch of nice skin care properties: it is very moisturizing, has soothing and antioxidant abilities as well as significant antibacterial and antifungal magic powers. There is also a lot of empirical evidence with emerging scientific backup that honey dressing promotes the healing of wounds and burns.
One tricky thing about honey though, is that it can have lots of different floral sources and different types of honey have a somewhat different composition and thus somewhat different properties. For example, the darker the honey the richer it is in antioxidant phenolic compounds. Two special types of honey are acacia and manuka. The former is unique and popular because of its higher than usual fructose content that makes it more water-soluble and easier to stabilize in cosmetic formulas. The latter comes from the Leptospermum Scoparium tree native to New Zeland and its special thing is its extra strong antibacterial power due to a unique component called methylglyoxal.
Overall, honey is a real skin-goodie in pretty much every shape and form, and it is a nice one to spot on the ingredient list.
A 100% natural and plant-derived moisturizer that mimics the natural carbohydrate fraction found in the upper layer of the skin. Its special magic power is to bind to the skin stronger and longer than other moisturizer ingredients do so it can keep the skin hydrated longer than usual.
An amino acid-based emulsifier that helps water and oil to mix and stay that way. It is considered as natural, environmentally friendly, and hypoallergenic.
It's the chemically chopped up version of normal lecithin. Most often it's used to create liposomes and to coat and stabilize other ingredients.
It's a little helper ingredient coming from corn, rice or potato starch that can help to keep skin mat (absorbent), to stabilise emulsions, and to keep the product together (binding).
A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.
Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.
It also occurs naturally in our body and is used as a food additive. As cosmetic chemist Colins writes it, "its safety really is beyond any doubt".
A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type and easy to formulate with. No wonder it’s popular.
A handy multi-tasker, white to light yellowish oil-loving wax that works very well in oil-in-water emulsions. It makes your skin feel nice and smooth (emollient), stabilizes oil-water mixes and gives body to them.
Oh, and one more thing: it's a so-called fatty alcohol - the good, emollient type of alcohol that is non-drying and non-irritating. It is often mixed with fellow fatty alcohol, Cetyl Alcohol, and the mixture is called Cetearyl Alcohol in the ingredient list.
A sugar based emulsifier that's especially great for low viscosity lotions or even sprays. It's effective in small amounts, only 1-1.5% is needed to form an emulsion. The resulting cream or lotion has great cosmetic properties with good spreadability and an enhanced soft skin feel.
Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA.
So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh.
There is also some research showing that citric acid with regular use (think three months and 20% concentration) can help sun-damaged skin, increase skin thickness and some nice hydrating things called glycosaminoglycans in the skin.
But according to a comparative study done in 1995, citric acid has less skin improving magic properties than glycolic or lactic acid. Probably that’s why citric acid is usually not used as an exfoliant but more as a helper ingredient in small amounts to adjust the pH of a formulation.
A little helper ingredient that is used to adjust the pH of the product. It also helps to keep products stay nice longer by neutralizing the metal ions in the formula (they usually come from water).
It's one of the important lipids that can be found naturally in the outer layer of the skin. About 25% of the goopy stuff between our skin cells consists of cholesterol. Together with ceramides and fatty acids, they play a vital role in having a healthy skin barrier and keeping the skin hydrated.
Apart from being an important skin-identical ingredient, it's also an emollient and stabilizer.
Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!).
If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.
Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!).
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| what‑it‑does | solvent |
| what‑it‑does | emollient |
| what‑it‑does | emollient |
| what‑it‑does | solvent | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | emollient |
| irritancy, com. | 0, 0 |
| what‑it‑does | antioxidant |
| irritancy, com. | 0, 0 |
| what‑it‑does | soothing | antioxidant |
| irritancy, com. | 0, 0 |
| what‑it‑does | soothing | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | soothing | antioxidant | antimicrobial/antibacterial |
| what‑it‑does | soothing | moisturizer/humectant | antimicrobial/antibacterial |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | emollient | emulsifying |
| what‑it‑does | emollient | emulsifying |
| irritancy, com. | 0, 1-2 |
| what‑it‑does | emollient |
| what‑it‑does | emollient | viscosity controlling | emulsifying | surfactant/cleansing |
| irritancy, com. | 2, 2 |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | buffering |
| what‑it‑does | chelating | buffering |
| what‑it‑does | skin-identical ingredient | emollient |
| irritancy, com. | 0, 0 |
| what‑it‑does | perfuming |