Enchanced Night Cream
Ingredients overview
Highlights
Key Ingredients
Other Ingredients
Skim through
Pure Biology Enchanced Night CreamIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.
It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols. Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tail part that makes them absolutely non-drying and non-irritating and are totally ok for the skin.
A common functional ingredient that helps to keep the oil-loving and water-loving ingredients together (emulsifier), stabilizes and thickens the products.
Chemically speaking, it is ethoxylated Cetearyl alcohol, meaning that some ethylene oxide is added to the fatty alcohol to increase the water-soluble part in the molecule. The result is that the mainly oil soluble, emollient fatty alcohol is converted to an emulsifier molecule that keeps oil and water mixed in creams. The number in the name of Ceteareth emulsifiers refers to the average number of ethylene oxide molecules added and 20 makes a good emulsifier.
An ester that comes from Cetearyl alcohol and the fatty acids of olive oil. It often comes to the formula coupled with Sorbitan Olivate as the two together form the well-known, natural emulsifier trade named Olivem 1000.
Other than helping oil and water to blend, the main thing of Olivem 1000 is generating liquid crystal structures that are similar to the lipid structures of the stratum corneum (the outermost layer of the skin). Thanks to this, Olivem 1000 doubles as an active ingredient with significant moisturizing, barrier-repairing and soothing properties.
It also helps to deliver water-soluble actives such as caffeine more effectively, and can even boost SPF in sunscreen formulas. Its typical use level is 1-5% and has wide compatibility with other actives and oils.
Overall, a real multi-tasker with nice sensorial properties. No wonder it is so popular.
An ester coming from sorbitol and the fatty acids of olive oil. It is part of the popular emulsifier trade named Olivem 1000 that is well-known for generating biomimetic liquid crystal structures. We have more info on Olivem 1000 at Cetearyl Olivate >>
A clear, colorless oil-like liquid that makes the skin feel smooth and nice (aka emollient) and it does so without it being greasy.
What's more, it can even reduce the heavy, greasy feel in products with high oil content. It's also fast-spreading meaning that it gives the formula a good, nice slip. It absorbs quickly into the skin and helps other ingredients to penetrate quicker and deeper.
Thanks to all this, it's one of the most commonly used emollients out there. There is just one little drawback: it has a high comedogenic index (5 out of 5...), so it might clog pores if you're prone to it.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
The oil coming from the seeds of the nice, little, yellow-flowered plant called Evening Primrose. Similar to other plant oils, it's loaded with nourishing and moisturizing fatty acids. It's a very rich source of linoleic acid (66-76%), and also contains the soothing and healing superstar fatty acid, gamma-linolenic acid (aka GLA, 7-12%) (Btw, the richest known source of GLA is the borage oil, but evening primrose still counts as a very good source of it). It also contains oleic acid, but not too much around 6-15%.
Since the 1980's, EPO is a well-known food supplement and there are quite a lot of studies examining what happens if you take it orally. It seems to be helpful with a bunch of things: atopic dermatitis, dry eyes, brittle nails, sunburn and even acne.
As for the skin, it's a great hydrating plant oil, that can also reduce inflammation and irritation. It's a superb healing agent that can truly help dry skin, not just on the surface by covering it (and not letting water to evaporate) but by initiating structural changes within the skin. If that's not enough, it also helps skin cell regeneration.
All in all, a real goodie especially for dry, easily irritated skin.
The oil coming from the pulp of one of the most nutritious fruits in the world, the avocado. It's loaded with the nourishing and moisturizing fatty acid, oleic (70%) and contains some others including palmitic (10%) and linoleic acid (8%). It also contains a bunch of minerals and vitamins A, E and D.
Avocado oil has extraordinary skin penetration abilities and can nourish different skin layers. It's a very rich, highly moisturizing emollient oil that makes the skin smooth and nourished. Thanks to its vitamin E content it also has some antioxidant properties. As a high-oleic plant oil, it is recommended for dry skin.
When it comes to cosmetic oils and hype, argan oil is for sure leading the way. Dubbed as the "liquid gold of Morocco", we have to admit we have some trouble determining why this oil enjoys such a special miracle status. Not that it's not good, it is good, even great but reading the research about argan and a bunch of other plant oils we just do not see the big, unique differentiating factor (though that might be our fault not reading enough, obvs.)
So, argan oil comes from the kernel of the argan fruit that comes from the argan tree that grows only in Morocco. The tree is slow growing and getting the oil is a hard job. The traditional process is that the ripe argan fruits fall from the tree, then goats eat them up and poop out the seeds. The seeds are collected and smashed with a stone to get the kernels inside. This part is the hard one as the seeds have extremely hard shells. Once the kernels are obtained, the oil is pressed out from them (the kernels contain about 50% oil).
As for skincare, argan oil is loaded with lots of skin goodies (but so are many other plant oils): it contains 80% nourishing and moisturizing unsaturated fatty acids, mainly oleic (38-50%), linoleic (28-38%) and palmitic (10-18%). It also contains a relatively large amount of antioxidant vitamin E (600-900 mg/kg, about twice as much as olive), small amounts of antioxidant phenols (including caffeic acid, ferulic acid, and epicatechin), as well as some rare sterols with soothing and anti-inflammatory properties.
Thanks to all the above goodness in argan oil, it can greatly nourish and moisturize the skin and hair. It's also claimed to be able to neutralize collagen-damaging free radicals, help reduce scars, and revitalize and improve skin elasticity. You can even read that argan might help acne-prone skin, but being a high oleic oil, we would be careful with that.
All in all, argan oil is a real goodie but we do not fully understand the special miracle status it enjoys.
A synthetic liquid oil that can replace mineral oil or silicone oils in the cosmetic formulas. There are different grades depending on the molecular weight ranging from very light, volatile, non-residue leaving ones to more substantial, slight residue leaving ones.
Apart from leaving the skin soft and smooth (emollient), it's also used as a waterproofing agent in sunscreens or makeup products and as a shine enhancer in lip gloss formulas.
A castor oil derived, white, lard-like helper ingredient that is used as a solubilizer to put fragrances (those are oil loving things) into water-based products such as toners.
A smallish polymer molecule (created from repeated units of Polyethylene glycol, aka PEG) that's used as a solubilizer and viscosity control agent.
It is a clear, colorless liquid that is water-soluble and water-binding (aka humectant) and can help to solubilize sparingly-water soluble things (e.g. vanilla, perfumes) into water-based formulas. Thanks to its water-binding ability, it also prevents the drying out of formulas, especially when combined with the fellow hygroscopic agent, sorbitol.
Unless you live under a rock you must have heard about shea butter. It's probably the most hyped up natural butter in skincare today. It comes from the seeds of African Shea or Karite Trees and used as a magic moisturizer and emollient.
But it's not only a simple emollient, it regenerates and soothes the skin, protects it from external factors (such as UV rays or wind) and is also rich in antioxidants (among others vitamin A, E, F, quercetin and epigallocatechin gallate). If you are looking for rich emollient benefits + more, shea is hard to beat.
It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.
As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution".
In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).
What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists.
If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
A super commonly used 5 unit long, cyclic structured silicone that is water-thin and does not stay on the skin but evaporates from it (called volatile silicone). Similar to other silicones, it gives skin and hair a silky, smooth feel.
It's often combined with the non-volatile (i.e. stays on the skin) dimethicone as the two together form a water-resistant, breathable protective barrier on the skin without a negative tacky feel.
A four-unit long, cyclic structured, super light silicone that is the small sister of the more commonly used 5-unit long cyclic structured Cyclopentasiloxane. It is a so-called volatile silicone that evaporates off the skin and hair rather than staying on it.
Similar to other silicones, it has excellent spreading properties and amazing silkiness. It is often blended with other silicones to achieve unique sensorial properties in the formula.
A thick, high molecular weight silicone that is usually diluted in another, lighter silicone fluid (like dimethicone or cyclopentasiloxane). The dimethiconol containing silicone blends leave a silky smooth, non-greasy film on the skin.
One of the 9 types of ceramides that can be found naturally in the upper layer of the skin. Ceramides make up a big part (about 50%) of the goopy stuff that's between our skin cells (called extracellular matrix) and play a super important role in having a healthy skin barrier and keeping the skin hydrated.
We wrote way more about ceramides at ceramide 1, so click here to know more.
A tripeptide (three amino acids attached to each other: Lys-Val-Lys) that's claimed to protect and boost collagen and improve skin texture.
The manufacturer did an in-vivo (made on real people) study with 45 volunteers and found that used twice daily for 84 days 1% and 2.5% Syn-Coll reduces the appearance of wrinkles by 7 and 12% respectively. In another study (also by the manufacturer) with 33 female Chinese volunteers, 77% of the participants felt that Syn-Coll visibly improved the firmness and elasticity of the skin after 4 weeks. What's more, 60% of the participants also noticed a reduction in the look of the pore size also after 4 weeks of treatment.
We don't have description for this ingredient yet.
Aloe Vera is one of today’s magic plants. It does have some very nice properties indeed, though famous dermatologist Leslie Baumann warns us in her book that most of the evidence is anecdotal and the plant might be a bit overhyped.
What research does confirm about Aloe is that it’s a great moisturizer and has several anti-inflammatory (among others contains salicylates, polysaccharides, magnesium lactate and C-glucosyl chromone) as well as some antibacterial components. It also helps wound healing and skin regeneration in general. All in all definitely a goodie.
It's an ester form of vitamin A (retinol + palmitic acid) that belongs to the "retinoid family". The retinoid family is pretty much the royal family of skincare, with the king being the FDA-approved anti-aging ingredient tretinoin. Retinol is also a very famous member of the family, but it's like Prince George, two steps away from the throne. Retinyl palmitate will be then Prince Charlotte (George's little sister), quite far (3 steps) away from the throne.
By steps, we mean metabolic steps. Tretinoin, aka retinoic acid, is the active ingredient our skin cells can understand and retinyl palmitate (RP) has to be converted by our metabolic machinery to actually do something. The conversion is a 3 step one and looks like this:
retinyl palmitate --> retinol -- > retinaldehyde --> all-trans-retinoic acid
As we wrote in our lengthy retinol description the problem is that the conversion is not terribly effective. The evidence that RP is still an effective anti-aging ingredient is not very strong, in fact, it's weak. Dr. Leslie Baumann in her fantastic Cosmetic Dermatology book writes that RP is topically ineffective.
What's more, the anti-aging effectiveness is not the only questionable thing about RP. It also exibits questionable behaviour in the presence of UV light and was the center of a debate between the non-profit group, EWG (whose intentions are no doubt good, but its credibility is often questioned by scientists) and a group of scientists and dermatologists lead by Steven Q. Wang, MD, director of dermatologic surgery at Memorial-Sloan Kettering Cancer Centre.
Dr. Leslie Baumann wrote a great review of the debate and summarized the research available about retinyl palmitate here. It seems that there is a study showing RP being photo protective against UVB rays but there is also a study showing RP causing DNA damage and cytotoxicity in association with UVA.
We think that the truth lies somewhere in the middle, and we agree with Dr. Baumann's conclusion: "sufficient evidence to establish a causal link between RP and skin cancer has not been produced. Nor, I’m afraid, are there any good reasons to recommend the use of RP". We would add especially during the day!
Bottom line: If you wanna get serious about retinoids, RP is not your ingredient (retinol or tretinoin is!). However, if you use a product that you like and it also contains RP, there is no reason to throw it away. If possible use it at night, just to be on the safe side.
Super common soothing ingredient. It can be found naturally in the roots & leaves of the comfrey plant, but more often than not what's in the cosmetic products is produced synthetically.
It's not only soothing but it' also skin-softening and protecting and can promote wound healing.
It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version.
According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E.
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
Exactly what it sounds: nice smelling stuff put into cosmetic products so that the end product also smells nice. Fragrance in the US and parfum in the EU is a generic term on the ingredient list that is made up of 30 to 50 chemicals on average (but it can have as much as 200 components!).
If you are someone who likes to know what you put on your face then fragrance is not your best friend - there's no way to know what’s really in it.
Also, if your skin is sensitive, fragrance is again not your best friend. It’s the number one cause of contact allergy to cosmetics. It’s definitely a smart thing to avoid with sensitive skin (and fragrance of any type - natural is just as allergic as synthetic, if not worse!).
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It’s not a strong one and doesn’t really work against bacteria, but more against mold and yeast. To do that it has to break down to its active form, sorbic acid. For that to happen, there has to be water in the product and the right pH value (pH 3-4).
But even if everything is right, it’s not enough on its own. If you see potassium sorbate you should see some other preservative next to it too.
BTW, it’s also a food preservative and even has an E number, E202.
A controversial preservative that has formaldehyde-releasing properties. It works great against bacteria and also has mild fungicide abilities.
Cosmetic chemist, Colin wrote a great article about formaldehyde and DMDM Hydantoin. He writes that formaldehyde is the perfect example of "the dose makes the poison" principle. It's a natural stuff that can also be found in fresh fruits and vegetables, and eating it in tiny amounts is totally ok. However, in larger amounts (according to Wikipedia 30 mL of a solution containing 37% formaldehyde) it's deadly.
The amount of formaldehyde used in cosmetics either neat or through formaldehyde-releasing preservatives is tiny. Probably that is why the Cosmetic Ingredient Review Broad concluded both in 1988 and in 2008 that DMDM Hydantoin is "safe as used in cosmetics".
However, Colins argues that in the case of formaldehyde-releasing preservatives, formaldehyde is released slowly and the skin has probably not evolved to deal with that. The lingering formaldehyde might be toxic to the Langerhans Cells that are important for the skin's defense system. Another potential issue is that formaldehyde-releasers might also release other things while reacting with amino acids in the skin that is probably the explanation why some people are not allergic to formaldehyde but are allergic to formaldehyde-releasing preservatives. These are all theories, far from proven facts, but we feel that there are some justified reasons why formaldehyde-releasing preservatives and Dmdm Hydantoin count as controversial.
All in all, it's up to you to decide if you wanna avoid this preservative group or not. If so, there are other, less risky and more skin-friendly options out there.
You may also want to take a look at...
| what‑it‑does | solvent |
| what‑it‑does | emollient | viscosity controlling | emulsifying | surfactant/cleansing |
| irritancy, com. | 1, 2 |
| what‑it‑does | emulsifying | surfactant/cleansing |
| irritancy, com. | 3, 2 |
| what‑it‑does | emulsifying |
| what‑it‑does | emulsifying |
| what‑it‑does | emollient | perfuming |
| irritancy, com. | 3, 3-5 |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | soothing | emollient |
| irritancy, com. | 2, 3 |
| what‑it‑does | antioxidant | emollient |
| irritancy, com. | 0, 0-3 |
| what‑it‑does | antioxidant | emollient |
| what‑it‑does | emollient | viscosity controlling |
| irritancy, com. | 2, 1 |
| what‑it‑does | emulsifying | surfactant/cleansing |
| what‑it‑does | moisturizer/humectant | solvent |
| what‑it‑does | emollient |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | emollient | solvent |
| what‑it‑does | emollient | solvent |
| what‑it‑does | emollient | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | cell-communicating ingredient |
| what‑it‑does | soothing | moisturizer/humectant |
| what‑it‑does | cell-communicating ingredient |
| irritancy, com. | 1-3, 1-3 |
| what‑it‑does | soothing |
| irritancy, com. | 0, 0 |
| what‑it‑does | antioxidant |
| irritancy, com. | 0, 0 |
| what‑it‑does | viscosity controlling |
| what‑it‑does | perfuming |
| what‑it‑does | preservative |
| what‑it‑does | preservative |
| what‑it‑does | preservative |