Ingredients overview
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Moleculogy Starter Facial WashIngredients explained
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
A 100% vegetable origin, biodegradable, mild cleansing agent that gives moderate to high amount of foam. It's happy to work together with other surfactants (in general, that helps to create milder formulas).
Super common ingredient in all kinds of cleansing products: face and body washes, shampoos and foam baths.
Number one reason for its popularity has to do with bubbles. Everyone loves bubbles. And cocamidopropyl betaine is great at stabilizing them.
The other reason is that it’s mild and works very well combined with other cleansing agents and surfactants. The art of cleansing is usually to balance between properly cleansing but not over-cleansing and cocamidopropyl betaine is helpful in pulling off this balance right.
Oh, and one more nice thing: even though it’s synthetic it’s highly biodegradable.
More info on CAPB on Collins Beaty Pages.
We don't have description for this ingredient yet.
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
A big polymer molecule that has a bunch of different versions and thus different uses. It can act as a film former, as a thickening agent, or it can increase the water-resistance in sunscreens. It is also used to entrap pigments/inorganic sunscreens within a micron size matrix for even coverage and easy application.
It’s a little helper ingredient that helps to set the pH of a cosmetic formulation to be just right. It’s very alkaline (you know the opposite of being very acidic): a 1% solution has a pH of around 10.
It does not have the very best safety reputation but in general, you do not have to worry about it.
What is true is that if a product contains so-called N-nitrogenating agents (e.g.: preservatives like 2-Bromo-2-Nitropropane-1,3-Diol, 5-Bromo-5-Nitro- 1,3-Dioxane or sodium nitrate - so look out for things with nitro, nitra in the name) that together with TEA can form some not nice carcinogenic stuff (that is called nitrosamines). But with proper formulation that does not happen, TEA in itself is not a bad guy.
But let’s assume a bad combination of ingredients were used and the nitrosamines formed. :( Even in that case you are probably fine because as far as we know it cannot penetrate the skin.
But to be on the safe side, if you see Triethanolamine in an INCI and also something with nitra, nitro in the name of it just skip the product, that cannot hurt.
- It's a helper ingredient that improves the freeze-thaw stability of products
- It's also a solvent, humectant and to some extent a penetration enhancer
- It has a bad reputation among natural cosmetics advocates but cosmetic scientists and toxicology experts do not agree (read more in the geeky details section)
Acetamidoethoxyethanol is a high-performance moisturizer that's claimed to give both amazing instant and longer term (up to 30 hours) hydration to the skin. It works through interacting with water and keratin (skin protein) to keep the water molecules tightly bound in the upper layer of the skin. This binding mechanism supposedly ensures that Acetamidoethoxyethanol gives great hydration initially as well as over 30 hours.
It's also non-sticky, spreads nicely and easily on the skin and plays well with other common ingredients in the formula.
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
Citric acid comes from citrus fruits and is an AHA. If these magic three letters don’t tell you anything, click here and read our detailed description on glycolic acid, the most famous AHA.
So citric acid is an exfoliant, that can - just like other AHAs - gently lift off the dead skin cells of your skin and make it more smooth and fresh.
There is also some research showing that citric acid with regular use (think three months and 20% concentration) can help sun-damaged skin, increase skin thickness and some nice hydrating things called glycosaminoglycans in the skin.
But according to a comparative study done in 1995, citric acid has less skin improving magic properties than glycolic or lactic acid. Probably that’s why citric acid is usually not used as an exfoliant but more as a helper ingredient in small amounts to adjust the pH of a formulation.
Super common little helper ingredient that helps products to remain nice and stable for a longer time. It does so by neutralizing the metal ions in the formula (that usually get into there from water) that would otherwise cause some not so nice changes.
It is typically used in tiny amounts, around 0.1% or less.
We don't have description for this ingredient yet.
A helper ingredient that's used as a co-emulsifier (meaning next to other emulsifiers in the formula it helps water and oil to mix) and as a stabilization agent for foams. Also, has some antimicrobial activity so it can help to boost the effectiveness of the preservative system.
An interesting polysaccharide (a big sugar molecule) obtained by bacterial fermentation. Its sugar sequence is rich in rhamnose, galactose, and glucuronic acid.
According to its manufacturer, Biosaccharide Gum-2 is a protecting agent against the damages from external aggressors that accelerate skin aging and it's a booster of skin comfort stimulating the release of pleasure molecules.
A really multi-functional helper ingredient that can do several things in a skincare product: it can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient, it can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products. And that is still not all: it can also boost the antimicrobial activity of preservatives.
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415).
We don't have description for this ingredient yet.
One of the many types of ceramides that can be found naturally in the upper layer of the skin. Ceramides make up about 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated. It works even better when combined with its pal, Ceramide 1.
We wrote way more about ceramides at ceramide 1, so click here to know more.
It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol.
The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.
A type of ceramide that can be found naturally in the upper layer of the skin. Ceramides make up 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated.
We have written way more about ceramides at ceramide 1, so click here to know more.
It's a type of lipid, a so-called sphingoid base that can be found naturally in the upper layer of the skin. It's found both in "free-form" and as part of famous skin lipids, ceramides.
There is emerging research about Phytosphingosine that shows that it has antimicrobial and cell-communicating properties and is considered part of the skin's natural defense system.
A 2007 study showed that Phytosphingosine even works against evil acne-causing bacteria, Propionibacterium acnes and shows promise as a complementing active ingredient in treating acne-prone skin thanks to its anti-inflammatory and antimicrobial activities.
A nice one to spot in the ingredient list. :)
It's one of the important lipids that can be found naturally in the outer layer of the skin. About 25% of the goopy stuff between our skin cells consists of cholesterol. Together with ceramides and fatty acids, they play a vital role in having a healthy skin barrier and keeping the skin hydrated.
Apart from being an important skin-identical ingredient, it's also an emollient and stabilizer.
A big molecule created from repeated subunits (a polymer of acrylic acid) that magically converts a liquid into a nice gel formula. It usually has to be neutralized with a base (such as sodium hydroxide) for the thickening to occur and it creates viscous, clear gels that also feel nice and non-tacky on the skin. No wonder, it is a very popular and common ingredient. Typically used at 1% or less in most formulations.
Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.
BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.
It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive.
A fancy name for sugar. Luckily when you put it on your skin it's good for you not like when you eat it. :) It has water-binding properties, which means that it helps to keep your skin nice and hydrated.
It’s the - sodium form - cousin of the famous NMF, hyaluronic acid (HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.
As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephen writes on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution".
In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checked Prospector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).
What seems to be a true difference, though, is that the salt form is more stable, easier to formulate and cheaper so it pops up more often on the ingredient lists.
If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
The extract of red seaweed that has nice film-forming, skin smoothing and moisturizing properties.
The manufacturer claims that thanks to biomimetic properties between skin proteins and carrageenans it has a very long-lasting action and can form a "second skin". It also gives a "slow-release" effect to oil-loving active ingredients and measurably reduces trans-epidermal water loss (that's pretty much a synonym of saying that it moisturizes the skin).
We don't have description for this ingredient yet.
Ceramides get quite a lot of hype recently and good news: there is a reason for that. But before we go into the details, let's just quickly define what the heck ceramides are:
They are waxy lipids that can be found naturally in the outer layer of the skin (called stratum corneum - SC). And they are there in big amounts! The goopy stuff between our skin cells is called extracellular matrix that consists mainly of lipids. And ceramides are about 50% of those lipids (the other important ones are cholesterol with 25% and fatty acids with 15%).
Ok, so now we know what ceramides are, let's see what they do in our skin: research shows clearly that they play a super important role in keeping the skin barrier healthy and the skin hydrated. If ceramides in the skin are decreased, more water can evaporate from the skin and there is less water remaining in the skin. So ceramides form kind of a "water-proof" protecting layer and make sure that our skin remains nice and hydrated.
Now the question is only this: If we put ceramides all over our face do they work as well as ceramides already naturally in our skin? Well, the answer is probably a no, but they do work to some extent. The BeautyBrains blog made a fantastic article about ceramides and they have listed a couple of examples about studies showing that ceramides - especially when used in certain ratios with cholesterol and fatty acids - do hydrate the skin and can help to repair the skin barrier.
So far we were writing about ceramides in plural. It's because there are lots of different ceramides, a 2014 article writes that currently 12 base classes of ceramides are known with over 340 specific species. Chemically speaking, ceramides are the connection of a fatty acid and a sphingoid base and both parts can have different variations that result in the different types of ceramides.
Our current one, Ceramide 1, or more recently called Ceramide EOP, was the first one that was identified in 1982 and it's a special snowflake. It contains the essential fatty acid, linoleic acid and has a unique structure. It's believed that ceramide 1 plays a "binding role" in the lipid layers of the extracellular matrix. Along with ceramides 4 and 7, they also play a vital role in epidermal integrity and serve as the main storage areas for linoleic acid (a fatty acid that's also very important for barrier repair).
Oh, and one more thing: alkaline pH inhibits enzymes that help ceramide synthesis in our skin. So if you use a soap and you notice your skin is becoming dry, now you know why.
Hydrolyzed Hyaluronic Acid is a low molecular weight, chemically chopped up version of the naturally big molecule and current IT-moisturizer, Hyaluronic Acid (HA). The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to retain water, making it plump and elastic. As HA is a polymer, the subunits can be repeated many times (as a high-molecular-weight version), or just a few times (as a low-molecular-weight version).
We wrote in detail at HA about how different molecular weight versions do different things both as a component of the skin and as a skincare ingredient, so click here and read about all the details. Hydrolyzed Hyaluronic Acid can also come in different molecular-weight versions with different properties:
- 100-300 kDa version: apart from moisturizing, this size might also help the skin to repair itself by increasing its self-defense. It is also claimed to boost the wound healing process and is especially helpful for sensitive skin types (acne, rosacea, inflammation-related skin diseases).
- 50k Da version: this is the size that is claimed to be able to absorb into the skin and plump up wrinkles, so it is used mainly as an "anti-aging ingredient"
- below 50k, around 10k Da version: there is a Japanese version trade named Hyalo-Oligo that has only a 10k molecular weight and is claimed to penetrate the skin very well, have a unique touch and give deep and long-lasting moisturization. Based on the Evonik-research and the natural role of LMW-HA in the body working as a pro-inflammatory signal molecule, this ultra-low molecular weight version is a controversial ingredient.
If you wanna become a real HA-and-the-skin expert, you can read much more about the topic at hyaluronic acid (including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
Sodium Acetylated Hyaluronate is a variation of current IT moisturizer, Hyaluronic acid, where some water-loving -OH groups are replaced by amphipathic (partly water-loving and partly water-hating) acetyl groups. The modified molecule is claimed to have even better moisture retention ability than normal HA and better affinity to the skin surface.
The better affinity comes from the acetyl groups that act as tiny "anchors" to attach the HA molecule to the skin. Staying on top of the skin better and longer means longer-lasting surface hydration and improved elasticity. It is also less sticky and more cosmetically elegant than normal HA, so no wonder the nickname of this molecule is super hyaluronic acid.
- It’s naturally in our skin and behaves there like a sponge
- It can bind up to 1000 times its own weight in water
- It is a big molecule from repeated subunits (polymer) so different molecular weight versions exist (unfortunately there is no way to determine MW from INCI list only)
- High-molecular-weight-HA (>500 kDa) is an excellent surface hydrator, skin protectant and can act as an osmotic pump helping water-soluble actives to penetrate deeper into the skin
- Low-molecular-weight-HA (< 500 kDa) can hydrate the skin somewhat deeper though it is still a big molecule and works mainly in the epidermis (outer layer of the skin)
- Low-molecular-weight-HA might also help the skin to repair itself by increasing its self-defense (~ 200kDa used in the study)
- Ultra-low-molecular-weight-HA (<50kDa) is a controversial ingredient and might work as a pro-inflammatory signal molecule
It's a special "cross-linked" from of IT-moisturizer, hyaluronic acid (HA). Cross-linked means that "normal" HA pieces (1-2 million Da molecular weight) are chemically bound togeather to create a big, "infinite" mesh.
The special HA mesh has a remarkable water-binding capacity, 5 times more than the already crazy water-binding capacity of "normal" HA. This water filled crosslinked HA gel forms a smooth film on the skin and continuously delivers the bound water, so it gives long-term moisturizing benefits.
Btw, crosslinking HA was developed for dermal fillers (as crosslinking helps their longevity), and this guy is the topical version of FDA approved dermal filler called Hylan B gel. Smearing crosslinked version all over ourselves is a newish thing, and incoming evidence so far suggests that it's a great idea, even better than normal HA.
A very recent, 2016 research article compared the topical moisturizing effect of crosslinked HA (not Hylan B gel specifically, but something called Resilient HA or RHA), HMW-HA and LMW-HA and found that "TEWL (that is trans-epidermal water loss, the water that evaporates from the skin) was reduced by 27.8% with RHA, and by 15.6% with HMW HA, but increased by 55.5% with LMW HA." (You can read much more about HMW and LMW HA here in the geeky details section.)
All in all, we think Sodium Hyaluronate Crosspolymer is an awesome version of HA, probably superior to traditional versions, so be happy to spot it on the ingredient list.
It's a super small, chemically chopped up version of sodium hyaluronate. Its trade name is miniHA, and its molecular weight is 10 kDa. This counts as really tiny given that "normal" HA has a molecular weight of 0.5-2 million Da.
To be honest, low molecular weight (LMW), and especially this ultra-low molecular weight HA is a controversial ingredient. On the upside, it can penetrate the skin better (though 10kDa still counts as big!) and might be able to moisturize the deeper layers of the skin where normal HA cannot get. Also, according to the manufacturer of miniHA, it has better antioxidant activity than a 1.6MDa version HA and it also has better sun protection and after-sun repair abilities than the higher MW versions. It also works in synergy with higher molecular weight versions, and the combination of 0.1% 1.45MDa-HA + 0.1% 380 kDa-HA + 0.1% miniHA hydrated the skin significantly better than 0.3% 1.45MDa-HA alone.
On the downside, the biological role of LMW-HA in the skin is being a pro-inflammatory signaling agent and there is a study by another manufacturer called Evonik showing that HA versions with smaller than 50kDa molecular weight might be pro-inflammatory when put on the skin. Granted, the study was only done on reconstituted human epidermis, so it might or might not be like this on real human skin.
If you wanna get confused and read much more about hyaluronic acid and what the different molecular weight versions might or might not do, click here and read our excruciatingly long description.
We don't have description for this ingredient yet.
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| what‑it‑does | solvent |
| what‑it‑does | surfactant/cleansing |
| what‑it‑does | surfactant/cleansing |
| what‑it‑does | surfactant/cleansing | surfactant/cleansing |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | viscosity controlling |
| what‑it‑does | buffering |
| irritancy, com. | 0, 2 |
| what‑it‑does | moisturizer/humectant | solvent |
| irritancy, com. | 0, 0 |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | preservative |
| what‑it‑does | buffering |
| what‑it‑does | chelating |
| what‑it‑does | perfuming | viscosity controlling |
| what‑it‑does | emulsifying |
| what‑it‑does | solvent |
| what‑it‑does | viscosity controlling |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | moisturizer/humectant | emollient |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | skin-identical ingredient | cell-communicating ingredient | anti-acne | antimicrobial/antibacterial |
| what‑it‑does | skin-identical ingredient | emollient |
| irritancy, com. | 0, 0 |
| what‑it‑does | viscosity controlling |
| irritancy, com. | 0, 1 |
| what‑it‑does | moisturizer/humectant | solvent |
| irritancy, com. | 0, 1 |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| irritancy, com. | 0, 0 |
| what‑it‑does | moisturizer/humectant | viscosity controlling |
| what‑it‑does | skin-identical ingredient |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | moisturizer/humectant |
| what‑it‑does | skin-identical ingredient | antioxidant | moisturizer/humectant |
| what‑it‑does | moisturizer/humectant |