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Hydrolyzed Sodium Hyaluronate

Also-called-like-this: miniHA
What-it-does: moisturizer/humectant

Details

It's a super small, chemically chopped up version of sodium hyaluronate. Its trade name is miniHA, and its molecular weight is 10 kDa. This counts as really tiny given that "normal" HA has a molecular weight of 0.5-2 million Da.

To be honest, low molecular weight (LMW), and especially this ultra-low molecular weight HA is a controversial ingredient. On the upside, it can penetrate the skin better (though 10kDa still counts as big!) and might be able to moisturize the deeper layers of the skin where normal HA cannot get. Also, according to the manufacturer of miniHA, it has better antioxidant activity than a 1.6MDa version HA and it also has better sun protection and after-sun repair abilities than the higher MW versions. It also works in synergy with higher molecular weight versions, and the combination of 0.1% 1.45MDa-HA + 0.1% 380 kDa-HA + 0.1% miniHA hydrated the skin significantly better than 0.3% 1.45MDa-HA alone.

On the downside, the biological role of LMW-HA in the skin is being a pro-inflammatory signaling agent and there is a study by another manufacturer called Evonik showing that HA versions with smaller than 50kDa molecular weight might be pro-inflammatory when put on the skin. Granted, the study was only done on reconstituted human epidermis, so it might or might not be like this on real human skin. 

If you wanna get confused and read much more about hyaluronic acid and what the different molecular weight versions might or might not do, click here and read our excruciatingly long description

Show me some proof

  • SOFW Journal, 11-2008, M. Farwick, P. Lersch, G. Strutz (Evonik), Low Molecular Weight Hyaluronic Acid: Its Effects on Epidermal Gene Expression and Skin Ageing

Products with Hydrolyzed Sodium Hyaluronate

HydroSkinCare Ha² Serum Comfort Zone Skin Regimen Ha Booster D'Care Face Up Double S Anti-Aging Serum The Ordinary Alpha Arbutin 2% + Ha Long 4 lashes Eyelash Serum Hylamide Booster;Low-Molecular Ha Perricone MD H2 Elemental Energy Hydrating Booster Serum Spring Letter Astaxanthin Essence Volition Celery Green Cream elf Hydrating Booster Drops NIOD Multi-Molecular Hyaluronic Complex Skinbetter Science Alto Defense Serum Wonjin Effect Medi Hydro Vial Mask BIOSSANCE Squalane + Micronutrient Fine Mist Farmacy Invincible NIOD Multi-Molecular Hyaluronic Complex 2 (Mmhc2) Farmacy Honey Drop Lightweight Moisturiser Peach and Lily Glass Skin Refining Serum Yoseido Birch Sap Concentrate Anti-Wrinkle Fresh Lotion Dermalogica Stress Positive Eye Lift DrJart+ Vital Hydra Solution Capsule Ampoule Hylamide Subq Anti-Age Advanced Serum Skin better Even Tone Correcting Serum™ Yoseido Birch Sap Concentrate Anti-Wrinkle Intense Lotion Yoseido Natural Birch Sap Nourishing Toner Intensive Moist Dermalogica Calm Water Gel Peter Thomas Roth Water Drench Hyaluronic Cloud Hydra-Gel Eye Patches SeneGence Facial Moisturizer Spf 20 Volition Rose Of Jericho Renewing Elixir COSRX Hydrium Watery Toner Farmacy Very Cherry Bright 15% Clean Vitamin C Serum With Acerola Cherry Honest Beauty Hydrogel Cream StriVectin Hyaluronic Dual Response Serum Estee Lauder Advanced Night Repair Intense Reset Concentrate Farmacy Clean Bee Ultra Gentle Facial Cleanser Ringana Anti-Wrinkle Serum Stubborn Cosmetics Skin Mercy Antioxidant Face Mist KORA ORGANICS Noni Bright Vitamin C Serum VENeffect Skin Calming Mist Benton Aloe Hyaluron Cream Farmacy Honeymoon Glow Aha Resurfacing Night Serum Stubborn Cosmetics Face Smooch Moisturizer (White Ingredients) dr. denese Firming Facial Collagen Night Serum Histoire Naturelle Lactobacillus Lotion Histoire Naturelle Lactobacillus Toner Honest Beauty Honestly Pure Retinol Serum Korres Black Pine 3D Sculpting, Firming & Lifting Face Serum Korres Golden Krocus Ageless Saffron Eye Elixir Stemm Density Stimuli KORA ORGANICS Noni Glow Sleeping Mask